NO984330D0 - Benzopyranderivater som har leukotrien-antagonistisk virkning - Google Patents

Benzopyranderivater som har leukotrien-antagonistisk virkning

Info

Publication number
NO984330D0
NO984330D0 NO984330A NO984330A NO984330D0 NO 984330 D0 NO984330 D0 NO 984330D0 NO 984330 A NO984330 A NO 984330A NO 984330 A NO984330 A NO 984330A NO 984330 D0 NO984330 D0 NO 984330D0
Authority
NO
Norway
Prior art keywords
pct
compounds
antagonistic effect
benzopyran derivatives
sec
Prior art date
Application number
NO984330A
Other languages
English (en)
Other versions
NO984330L (no
NO319612B1 (no
Inventor
Germano Carganico
David Mauleon Casellas
Jaime Pascual Avellana
Ma Luisa Garcia Perez
Albert Palomer Benet
Original Assignee
Menarini Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Menarini Lab filed Critical Menarini Lab
Publication of NO984330D0 publication Critical patent/NO984330D0/no
Publication of NO984330L publication Critical patent/NO984330L/no
Publication of NO319612B1 publication Critical patent/NO319612B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/14Decongestants or antiallergics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/45Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/54Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition of compounds containing doubly bound oxygen atoms, e.g. esters
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/24Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Otolaryngology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
NO19984330A 1996-03-21 1998-09-17 Benzopyranderivater som har leukotrien-antagonistisk virkning, fremgangsmate for fremstilling og anvendelse derav NO319612B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES009600682A ES2127106B1 (es) 1996-03-21 1996-03-21 Derivados benzopiranicos con accion antagonista de los leucotrienos, procedimiento para su preparacion y utilizacion de los mismos.
PCT/EP1997/001418 WO1997034885A1 (en) 1996-03-21 1997-03-20 Benzopyran derivatives having leukotriene-antagonistic action

Publications (3)

Publication Number Publication Date
NO984330D0 true NO984330D0 (no) 1998-09-17
NO984330L NO984330L (no) 1998-10-09
NO319612B1 NO319612B1 (no) 2005-08-29

Family

ID=8294261

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19984330A NO319612B1 (no) 1996-03-21 1998-09-17 Benzopyranderivater som har leukotrien-antagonistisk virkning, fremgangsmate for fremstilling og anvendelse derav

Country Status (31)

Country Link
US (1) US5990142A (no)
EP (1) EP0888327B1 (no)
JP (1) JP3914575B2 (no)
KR (1) KR100378892B1 (no)
CN (1) CN1182129C (no)
AT (1) ATE219073T1 (no)
AU (1) AU707282B2 (no)
BG (1) BG63433B1 (no)
BR (1) BR9708215A (no)
CA (1) CA2249402C (no)
CU (1) CU22777A3 (no)
CZ (1) CZ296260B6 (no)
DE (1) DE69713300T2 (no)
DK (1) DK0888327T3 (no)
EA (1) EA001680B1 (no)
EE (1) EE03526B1 (no)
ES (2) ES2127106B1 (no)
GE (1) GEP20012416B (no)
HK (1) HK1018701A1 (no)
HU (1) HUP9901326A3 (no)
IL (1) IL126296A (no)
NO (1) NO319612B1 (no)
NZ (1) NZ331953A (no)
PL (1) PL189562B1 (no)
PT (1) PT888327E (no)
RS (1) RS49588B (no)
SI (1) SI0888327T1 (no)
SK (1) SK282979B6 (no)
TR (1) TR199801857T2 (no)
UA (1) UA65535C2 (no)
WO (1) WO1997034885A1 (no)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE397672T1 (de) 1999-11-24 2008-06-15 Univ New York State Res Found Katalytische rnas mit aminoacylierender aktivität
CA2476425C (en) * 2002-02-15 2012-04-17 The Research Foundation Of State University Of New York At Buffalo Ribozymes with broad trna aminoacylation activity
WO2004035741A2 (en) * 2002-10-17 2004-04-29 Decode Genetics Ehf. Susceptibility gene for myocardial infarction; methods of treatment
US7851486B2 (en) 2002-10-17 2010-12-14 Decode Genetics Ehf. Susceptibility gene for myocardial infarction, stroke, and PAOD; methods of treatment
ITTO20030140U1 (it) * 2003-09-16 2005-03-17 Interfila Srl Matita cosmetica
US20050065099A1 (en) * 2003-09-19 2005-03-24 Gail Walkinshaw Treatment of mitochondrial diseases
CN100475781C (zh) * 2004-02-13 2009-04-08 沃尼尔·朗伯有限责任公司 雄激素受体调节剂
AP2006003700A0 (en) 2004-02-13 2006-08-31 Warner Lambert Co Androgen receptor modulators
US7507860B2 (en) 2004-04-13 2009-03-24 Pfizer Inc. Androgen modulators
BRPI0513020A (pt) * 2004-07-08 2008-04-22 Warner Lambert Co moduladores de andrÈgenio, seus usos, composição farmacêutica, formulação farmacêutica tópica e artigo de fabricação
EP1781599A1 (en) * 2004-08-18 2007-05-09 Warner-Lambert Company LLC Androgen modulators
TW200724139A (en) * 2005-05-05 2007-07-01 Warner Lambert Co Androgen modulators
US20090170886A1 (en) * 2005-08-08 2009-07-02 Pfizer Inc Androgen modulators
JP5119444B2 (ja) * 2005-12-06 2013-01-16 国立大学法人 東京大学 多目的アシル化触媒とその用途
ITMI20061606A1 (it) * 2006-08-09 2008-02-10 Dipharma Spa Procedimento per la preparazione di composti nitrilici
CN102304052A (zh) * 2011-07-28 2012-01-04 浙江大学 一种制备5-溴-2-羟基-3-硝基苯乙酮的方法
CN103980257B (zh) * 2014-05-28 2016-04-27 苏州开元民生科技股份有限公司 8-硝基-2-四氮唑基-4-羰基苯并吡喃的合成方法
CN104402711A (zh) * 2014-11-12 2015-03-11 平湖优康药物研发有限公司 一种抗哮喘药物普伦斯特中间体的合成工艺
CN113651788B (zh) * 2021-09-16 2023-11-21 东华理工大学 一种3-胺烷基色酮化合物及其制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4977162A (en) * 1989-07-13 1990-12-11 Rorer Pharmaceutical Corporation Quinolinyl-chromone derivatives and use for treatment of hypersensitive ailments
JPH0395144A (ja) * 1989-08-04 1991-04-19 Ono Pharmaceut Co Ltd アミノフェノール誘導体の製造方法

Also Published As

Publication number Publication date
ES2127106B1 (es) 1999-11-16
CA2249402A1 (en) 1997-09-25
PL329027A1 (en) 1999-03-01
HUP9901326A3 (en) 2000-12-28
AU2158797A (en) 1997-10-10
US5990142A (en) 1999-11-23
GEP20012416B (en) 2001-04-25
SK282979B6 (sk) 2003-01-09
CN1214048A (zh) 1999-04-14
WO1997034885A1 (en) 1997-09-25
EP0888327B1 (en) 2002-06-12
HK1018701A1 (en) 1999-12-30
DE69713300T2 (de) 2002-09-26
CZ296260B6 (cs) 2006-02-15
DK0888327T3 (da) 2002-09-16
JP3914575B2 (ja) 2007-05-16
CA2249402C (en) 2006-10-24
EA001680B1 (ru) 2001-06-25
CN1182129C (zh) 2004-12-29
EE9800318A (et) 1999-04-15
PT888327E (pt) 2002-11-29
SI0888327T1 (en) 2002-10-31
SK127298A3 (en) 1999-03-12
DE69713300D1 (de) 2002-07-18
NZ331953A (en) 1999-03-29
ATE219073T1 (de) 2002-06-15
EA199800738A1 (ru) 1999-06-24
HUP9901326A2 (hu) 1999-08-30
TR199801857T2 (xx) 1998-12-21
CU22777A3 (es) 2002-07-24
BR9708215A (pt) 2000-01-04
KR20000064682A (ko) 2000-11-06
BG102775A (en) 1999-08-31
KR100378892B1 (ko) 2005-11-14
NO984330L (no) 1998-10-09
NO319612B1 (no) 2005-08-29
IL126296A (en) 2002-08-14
EP0888327A1 (en) 1999-01-07
ES2127106A1 (es) 1999-04-01
YU40798A (en) 1999-11-22
AU707282B2 (en) 1999-07-08
BG63433B1 (bg) 2002-01-31
JP2000506878A (ja) 2000-06-06
EE03526B1 (et) 2001-10-15
PL189562B1 (pl) 2005-08-31
UA65535C2 (en) 2004-04-15
IL126296A0 (en) 1999-05-09
RS49588B (sr) 2007-06-04
CZ299598A3 (cs) 1999-03-17
ES2176719T3 (es) 2002-12-01

Similar Documents

Publication Publication Date Title
NO984330D0 (no) Benzopyranderivater som har leukotrien-antagonistisk virkning
DK0687268T3 (da) Spiroazacykliske derivater som substans P-antagonister
SE9504661D0 (sv) New compounds
BR0315296A (pt) Derivados do ciclohexanol espirocìclicos
NO992400L (no) Nye substituerte pyrazolderivater
TR200200579T2 (tr) Amino-tirazolpiridin türevleri.
SE9604786D0 (sv) New compounds
NO991732L (no) Nye heterocyklylmetylsubstituerte pyrazolderivater
BR0209580A (pt) Derivados de ciclohexan-1, 4 diamina substituìdos
TR200101969T2 (tr) Enflamasyon tedavisi için sübstitüe edilmiş benzopiran analogları.
TNSN05045A1 (en) Indole or benzimidazole derivatives for modulating ikappab kinase
ES2164657T3 (es) Derivados aza-biciclicos puenteados como antagonistas de la sustancia p.
AU2003282233A1 (en) Quinoline derivatives as glucokinase ligands
MX9804597A (es) Derivados de bencimidazol sustituidos por naftilo como anticoagulantes.
NO965516D0 (no) Sterolderivater anvendt til regulering av meiose
FI964332A (fi) Eräiden metaanibisfosfonihappojohdannaisten käyttö proteesin löystymisen ja proteesin vaelluksen estämiseen
BR9610277A (pt) Derivados de piperazino como antagonistas de neurowuinina
DE69523155D1 (de) Benzimidazolonderivate mit zentraler dopaminerger aktivität
SE9802208D0 (sv) Novel compounds
MX9300779A (es) 3-(1h-tetrazol-5-y1)-4h-pyrido[1,2-a]pirimidina-4-onas composiciones farmaceuticas que las contienen y su preparacion de las mismas
UY26426A1 (es) Nuevos compuestos
SE9802209D0 (sv) Novel compounds
SE9504662D0 (sv) New compounds
NO992066L (no) Piperazinoderivater som neurokininantagonister
DK0891326T3 (da) Nye D-vitaminanaloger

Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees