ES2127106A1 - Derivados benzopiranicos con accion antagonista de los leucotrienos, procedimiento para su preparacion y utilizacion de los mismos. - Google Patents
Derivados benzopiranicos con accion antagonista de los leucotrienos, procedimiento para su preparacion y utilizacion de los mismos.Info
- Publication number
- ES2127106A1 ES2127106A1 ES09600682A ES9600682A ES2127106A1 ES 2127106 A1 ES2127106 A1 ES 2127106A1 ES 09600682 A ES09600682 A ES 09600682A ES 9600682 A ES9600682 A ES 9600682A ES 2127106 A1 ES2127106 A1 ES 2127106A1
- Authority
- ES
- Spain
- Prior art keywords
- group
- leukotriene
- benzopyran derivatives
- so2nr
- ch2o
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/45—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
- C07C45/54—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition of compounds containing doubly bound oxygen atoms, e.g. esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- C07D311/24—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Rheumatology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Dermatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Urology & Nephrology (AREA)
- Ophthalmology & Optometry (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pain & Pain Management (AREA)
- Otolaryngology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrane Compounds (AREA)
Abstract
Derivados benzopiránicos con acción antagonista de los leucotrienos, procedimiento para su preparación y utilización de los mismos. La invención describe derivados de fórmula I, A es un átomo de oxígeno, azufre o un grupo metileno; B y C son: a) cuando B es un heterociclo benzofusionado, U es un átomo de oxígeno, azufre o nitrógeno, Z-Y son átomos de carbono unidos por un enlace doble o sencillo y T es un enlace sencillo, un grupo metileno o carbonilo, C puede ser un grupo -CON{sup,7 R-, CSNR{sup,7 -, SO{sub,2 NR{sup,7 -, CH{sub,2 O-, -CH=CH-; b) cuando B es un grupo fenilo, C puede ser un grupo -SO{sub,2 NR{sup,7 -, CH{sub,2 O-, -CH=CH-; D es un grupo 5-tetrazolilo o -COOR{sup,8 , R{sup,8 es hidrógeno, (C{sub,1 -C{sub,4 )-alquilo o un grupo fenilalquilo; m y n son enteros entre 0 y 4. Presentan acción antagonista de los leucotrienos. Son utilizados como antiinflamatorios, antialérgicos o para tratamiento de enfermedades cardiovasculares.
Priority Applications (32)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES009600682A ES2127106B1 (es) | 1996-03-21 | 1996-03-21 | Derivados benzopiranicos con accion antagonista de los leucotrienos, procedimiento para su preparacion y utilizacion de los mismos. |
SI9730340T SI0888327T1 (en) | 1996-03-21 | 1997-03-20 | Benzopyran derivatives having leukotriene-antagonistic action |
EA199800738A EA001680B1 (ru) | 1996-03-21 | 1997-03-20 | Производные бензопирана, обладающие антагонистическим действием в отношении лейкотриена |
EE9800318A EE03526B1 (et) | 1996-03-21 | 1997-03-20 | Leukotrieen-antagonistliku toimega bensopüraanderivaadid, nende valmistamismeetod ja kasutamine |
US09/142,922 US5990142A (en) | 1996-03-21 | 1997-03-20 | Benzopyran derivatives having leukotriene-antagonistic action |
ES97914280T ES2176719T3 (es) | 1996-03-21 | 1997-03-20 | Derivados de benzopirano que tienen una accion antagonista de leucotrienos. |
BR9708215-5A BR9708215A (pt) | 1996-03-21 | 1997-03-20 | Derivados de benzopirano contendo ação antagonista de leucotrieno. |
KR10-1998-0707399A KR100378892B1 (ko) | 1996-03-21 | 1997-03-20 | 류코트리엔-길항활성을갖는벤조피란유도체 |
SK1272-98A SK282979B6 (sk) | 1996-03-21 | 1997-03-20 | Benzopyránové deriváty, spôsob ich prípravy a ich použitie |
UA98094930A UA65535C2 (en) | 1996-03-21 | 1997-03-20 | Benzopyran derivatives and a method for the preparation thereof |
CNB971931933A CN1182129C (zh) | 1996-03-21 | 1997-03-20 | 具有白细胞三烯拮抗作用的苯并吡喃衍生物 |
IL12629697A IL126296A (en) | 1996-03-21 | 1997-03-20 | Benzopyran derivatives having leukotriene antagonistic action, their preparation and pharmaceutical compositions containing them |
PT97914280T PT888327E (pt) | 1996-03-21 | 1997-03-20 | Derivados de benzopirano que possuem uma accao antagonistica dos leucotrienos |
NZ331953A NZ331953A (en) | 1996-03-21 | 1997-03-20 | Benzopyran derivatives having leukotriene-antagonistic action |
AU21587/97A AU707282B2 (en) | 1996-03-21 | 1997-03-20 | Benzopyran derivatives having leukotriene-antagonistic action |
DE69713300T DE69713300T2 (de) | 1996-03-21 | 1997-03-20 | Benzopyran derivate mit leukotrien-antagonistischer wirkung |
HU9901326A HUP9901326A3 (en) | 1996-03-21 | 1997-03-20 | Benzopyran derivatives having leukotriene-antagonistic action, pharmaceutical compositions containing these compounds, process for the preparation and use of these compounds and compositions |
EP97914280A EP0888327B1 (en) | 1996-03-21 | 1997-03-20 | Benzopyran derivatives having leukotriene-antagonistic action |
PCT/EP1997/001418 WO1997034885A1 (en) | 1996-03-21 | 1997-03-20 | Benzopyran derivatives having leukotriene-antagonistic action |
JP53315997A JP3914575B2 (ja) | 1996-03-21 | 1997-03-20 | ロイコトリエンアンタゴニスト作用を有するベンゾピラン誘導体 |
AT97914280T ATE219073T1 (de) | 1996-03-21 | 1997-03-20 | Benzopyran derivate mit leukotrien- antagonistischer wirkung |
DK97914280T DK0888327T3 (da) | 1996-03-21 | 1997-03-20 | Benzopyranderivater, som har antagonistisk virkning imod leukotriener |
CZ0299598A CZ296260B6 (cs) | 1996-03-21 | 1997-03-20 | Benzopyranové deriváty, zpusob jejich výroby a farmaceutický prostredek |
PL97329027A PL189562B1 (pl) | 1996-03-21 | 1997-03-20 | Pochodne benzopiranu o działaniu antagonistycznymdla leukotrienu i sposób ich wytwarzania |
TR1998/01857T TR199801857T2 (xx) | 1996-03-21 | 1997-03-20 | L�kotrien-antagonistik etkisine sahip olan benzopiran t�revleri. |
GEAP19974493A GEP20012416B (en) | 1996-03-21 | 1997-03-20 | Benzopyran Derivatives Having Leukotriene-Antagonistic Action |
CA002249402A CA2249402C (en) | 1996-03-21 | 1997-03-20 | Benzopyran derivatives having leukotriene-antagonistic action |
BG102775A BG63433B1 (bg) | 1996-03-21 | 1998-09-17 | Бензопиранови производни, имащи антагонистично действие спрямо левкотриени |
NO19984330A NO319612B1 (no) | 1996-03-21 | 1998-09-17 | Benzopyranderivater som har leukotrien-antagonistisk virkning, fremgangsmate for fremstilling og anvendelse derav |
YUP-407/98A RS49588B (sr) | 1996-03-21 | 1998-09-18 | Derivati benzopirana koji poseduju leukotrien-antagonističko dejstvo |
CU1998130A CU22777A3 (es) | 1996-03-21 | 1998-09-18 | Derivados de benzopirano que tienen acción antagonista para el leucotrieno |
HK99103747A HK1018701A1 (en) | 1996-03-21 | 1999-08-31 | Benzopyran derivatives having leukotriene-antagonistic action. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES009600682A ES2127106B1 (es) | 1996-03-21 | 1996-03-21 | Derivados benzopiranicos con accion antagonista de los leucotrienos, procedimiento para su preparacion y utilizacion de los mismos. |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2127106A1 true ES2127106A1 (es) | 1999-04-01 |
ES2127106B1 ES2127106B1 (es) | 1999-11-16 |
Family
ID=8294261
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES009600682A Expired - Lifetime ES2127106B1 (es) | 1996-03-21 | 1996-03-21 | Derivados benzopiranicos con accion antagonista de los leucotrienos, procedimiento para su preparacion y utilizacion de los mismos. |
ES97914280T Expired - Lifetime ES2176719T3 (es) | 1996-03-21 | 1997-03-20 | Derivados de benzopirano que tienen una accion antagonista de leucotrienos. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES97914280T Expired - Lifetime ES2176719T3 (es) | 1996-03-21 | 1997-03-20 | Derivados de benzopirano que tienen una accion antagonista de leucotrienos. |
Country Status (31)
Country | Link |
---|---|
US (1) | US5990142A (es) |
EP (1) | EP0888327B1 (es) |
JP (1) | JP3914575B2 (es) |
KR (1) | KR100378892B1 (es) |
CN (1) | CN1182129C (es) |
AT (1) | ATE219073T1 (es) |
AU (1) | AU707282B2 (es) |
BG (1) | BG63433B1 (es) |
BR (1) | BR9708215A (es) |
CA (1) | CA2249402C (es) |
CU (1) | CU22777A3 (es) |
CZ (1) | CZ296260B6 (es) |
DE (1) | DE69713300T2 (es) |
DK (1) | DK0888327T3 (es) |
EA (1) | EA001680B1 (es) |
EE (1) | EE03526B1 (es) |
ES (2) | ES2127106B1 (es) |
GE (1) | GEP20012416B (es) |
HK (1) | HK1018701A1 (es) |
HU (1) | HUP9901326A3 (es) |
IL (1) | IL126296A (es) |
NO (1) | NO319612B1 (es) |
NZ (1) | NZ331953A (es) |
PL (1) | PL189562B1 (es) |
PT (1) | PT888327E (es) |
RS (1) | RS49588B (es) |
SI (1) | SI0888327T1 (es) |
SK (1) | SK282979B6 (es) |
TR (1) | TR199801857T2 (es) |
UA (1) | UA65535C2 (es) |
WO (1) | WO1997034885A1 (es) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE60039120D1 (de) | 1999-11-24 | 2008-07-17 | Univ New York State Res Found | Katalytische rnas mit aminoacylierender aktivität |
ATE437946T1 (de) * | 2002-02-15 | 2009-08-15 | Univ New York State Res Found | Ribozyme mit breiter trna-aminoacylierungswirkung |
US7851486B2 (en) | 2002-10-17 | 2010-12-14 | Decode Genetics Ehf. | Susceptibility gene for myocardial infarction, stroke, and PAOD; methods of treatment |
WO2004035741A2 (en) * | 2002-10-17 | 2004-04-29 | Decode Genetics Ehf. | Susceptibility gene for myocardial infarction; methods of treatment |
ITTO20030140U1 (it) * | 2003-09-16 | 2005-03-17 | Interfila Srl | Matita cosmetica |
US7470798B2 (en) | 2003-09-19 | 2008-12-30 | Edison Pharmaceuticals, Inc. | 7,8-bicycloalkyl-chroman derivatives |
CN100475781C (zh) * | 2004-02-13 | 2009-04-08 | 沃尼尔·朗伯有限责任公司 | 雄激素受体调节剂 |
BRPI0507670A (pt) * | 2004-02-13 | 2007-07-17 | Warner Lambert Co | moduladores do receptor de androgênio |
WO2005100305A1 (en) | 2004-04-13 | 2005-10-27 | Warner-Lambert Company Llc | Androgen modulators |
BRPI0513020A (pt) * | 2004-07-08 | 2008-04-22 | Warner Lambert Co | moduladores de andrÈgenio, seus usos, composição farmacêutica, formulação farmacêutica tópica e artigo de fabricação |
CA2573457A1 (en) * | 2004-08-18 | 2006-02-23 | Warner-Lambert Company Llc | 4-(2-methoxy-phenoxy)-2-trifluoromethyl-benzonitrile as an androgen modulator |
TW200724139A (en) | 2005-05-05 | 2007-07-01 | Warner Lambert Co | Androgen modulators |
US20090170886A1 (en) * | 2005-08-08 | 2009-07-02 | Pfizer Inc | Androgen modulators |
US8188260B2 (en) * | 2005-12-06 | 2012-05-29 | The University Of Tokyo | Versatile acylation catalytic RNAs and uses thereof |
ITMI20061606A1 (it) * | 2006-08-09 | 2008-02-10 | Dipharma Spa | Procedimento per la preparazione di composti nitrilici |
CN102304052A (zh) * | 2011-07-28 | 2012-01-04 | 浙江大学 | 一种制备5-溴-2-羟基-3-硝基苯乙酮的方法 |
CN103980257B (zh) * | 2014-05-28 | 2016-04-27 | 苏州开元民生科技股份有限公司 | 8-硝基-2-四氮唑基-4-羰基苯并吡喃的合成方法 |
CN104402711A (zh) * | 2014-11-12 | 2015-03-11 | 平湖优康药物研发有限公司 | 一种抗哮喘药物普伦斯特中间体的合成工艺 |
CN113651788B (zh) * | 2021-09-16 | 2023-11-21 | 东华理工大学 | 一种3-胺烷基色酮化合物及其制备方法 |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0395144A (ja) * | 1989-08-04 | 1991-04-19 | Ono Pharmaceut Co Ltd | アミノフェノール誘導体の製造方法 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4977162A (en) * | 1989-07-13 | 1990-12-11 | Rorer Pharmaceutical Corporation | Quinolinyl-chromone derivatives and use for treatment of hypersensitive ailments |
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1996
- 1996-03-21 ES ES009600682A patent/ES2127106B1/es not_active Expired - Lifetime
-
1997
- 1997-03-20 GE GEAP19974493A patent/GEP20012416B/en unknown
- 1997-03-20 WO PCT/EP1997/001418 patent/WO1997034885A1/en active IP Right Grant
- 1997-03-20 SK SK1272-98A patent/SK282979B6/sk not_active IP Right Cessation
- 1997-03-20 KR KR10-1998-0707399A patent/KR100378892B1/ko not_active IP Right Cessation
- 1997-03-20 PL PL97329027A patent/PL189562B1/pl not_active IP Right Cessation
- 1997-03-20 NZ NZ331953A patent/NZ331953A/xx not_active IP Right Cessation
- 1997-03-20 CN CNB971931933A patent/CN1182129C/zh not_active Expired - Fee Related
- 1997-03-20 IL IL12629697A patent/IL126296A/en not_active IP Right Cessation
- 1997-03-20 AT AT97914280T patent/ATE219073T1/de not_active IP Right Cessation
- 1997-03-20 BR BR9708215-5A patent/BR9708215A/pt not_active Application Discontinuation
- 1997-03-20 AU AU21587/97A patent/AU707282B2/en not_active Ceased
- 1997-03-20 CZ CZ0299598A patent/CZ296260B6/cs not_active IP Right Cessation
- 1997-03-20 HU HU9901326A patent/HUP9901326A3/hu unknown
- 1997-03-20 JP JP53315997A patent/JP3914575B2/ja not_active Expired - Fee Related
- 1997-03-20 TR TR1998/01857T patent/TR199801857T2/xx unknown
- 1997-03-20 SI SI9730340T patent/SI0888327T1/xx unknown
- 1997-03-20 EP EP97914280A patent/EP0888327B1/en not_active Expired - Lifetime
- 1997-03-20 US US09/142,922 patent/US5990142A/en not_active Expired - Fee Related
- 1997-03-20 EE EE9800318A patent/EE03526B1/xx not_active IP Right Cessation
- 1997-03-20 EA EA199800738A patent/EA001680B1/ru unknown
- 1997-03-20 CA CA002249402A patent/CA2249402C/en not_active Expired - Fee Related
- 1997-03-20 PT PT97914280T patent/PT888327E/pt unknown
- 1997-03-20 UA UA98094930A patent/UA65535C2/uk unknown
- 1997-03-20 DE DE69713300T patent/DE69713300T2/de not_active Expired - Fee Related
- 1997-03-20 ES ES97914280T patent/ES2176719T3/es not_active Expired - Lifetime
- 1997-03-20 DK DK97914280T patent/DK0888327T3/da active
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1998
- 1998-09-17 NO NO19984330A patent/NO319612B1/no not_active IP Right Cessation
- 1998-09-17 BG BG102775A patent/BG63433B1/bg unknown
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1999
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Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0395144A (ja) * | 1989-08-04 | 1991-04-19 | Ono Pharmaceut Co Ltd | アミノフェノール誘導体の製造方法 |
Non-Patent Citations (1)
Title |
---|
CHEMICAL ABSTRACTS, Vol. 115, no 17, 1991, abstract 182817, pagina 874 & JP 03095144 A (ONO PHARMA) 19.04.1991 * |
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