NO975901L - Vinyl-pyrrolidinon cefalosporiner med basiske substituenter - Google Patents
Vinyl-pyrrolidinon cefalosporiner med basiske substituenterInfo
- Publication number
- NO975901L NO975901L NO975901A NO975901A NO975901L NO 975901 L NO975901 L NO 975901L NO 975901 A NO975901 A NO 975901A NO 975901 A NO975901 A NO 975901A NO 975901 L NO975901 L NO 975901L
- Authority
- NO
- Norway
- Prior art keywords
- formula
- cephalosporins
- compounds
- vinyl pyrrolidinone
- basic substituents
- Prior art date
Links
- 229930186147 Cephalosporin Natural products 0.000 title abstract 2
- 229940124587 cephalosporin Drugs 0.000 title abstract 2
- -1 Vinyl pyrrolidinone cephalosporins Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- 208000035473 Communicable disease Diseases 0.000 abstract 2
- 150000002148 esters Chemical class 0.000 abstract 2
- 238000011321 prophylaxis Methods 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 238000011282 treatment Methods 0.000 abstract 2
- 239000013543 active substance Substances 0.000 abstract 1
- 150000001780 cephalosporins Chemical class 0.000 abstract 1
- 150000004677 hydrates Chemical class 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/572—Five-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
- C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP96120472 | 1996-12-19 | ||
| EP97119528 | 1997-11-07 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO975901D0 NO975901D0 (no) | 1997-12-16 |
| NO975901L true NO975901L (no) | 1998-06-22 |
Family
ID=26142379
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO975901A NO975901L (no) | 1996-12-19 | 1997-12-16 | Vinyl-pyrrolidinon cefalosporiner med basiske substituenter |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US5981519A (ko) |
| EP (1) | EP0849269B9 (ko) |
| JP (2) | JP3264877B2 (ko) |
| KR (3) | KR100395985B1 (ko) |
| CN (5) | CN1104436C (ko) |
| AT (1) | ATE220402T1 (ko) |
| AU (1) | AU729653B2 (ko) |
| CA (2) | CA2628224C (ko) |
| CY (1) | CY2400B1 (ko) |
| CZ (1) | CZ405797A3 (ko) |
| DE (1) | DE69713865T2 (ko) |
| DK (1) | DK0849269T3 (ko) |
| ES (1) | ES2179996T3 (ko) |
| HU (1) | HUP9702474A3 (ko) |
| IL (1) | IL122604A0 (ko) |
| MA (1) | MA26457A1 (ko) |
| NO (1) | NO975901L (ko) |
| NZ (1) | NZ329363A (ko) |
| PT (1) | PT849269E (ko) |
| TW (1) | TW415949B (ko) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5977381A (en) * | 1998-01-12 | 1999-11-02 | Hoffmann-La Roche Inc. | Process for making 3-amino-pyrolidine derivatives |
| IL139872A0 (en) * | 1998-06-15 | 2002-02-10 | Hoffmann La Roche | Derivatives of 3-(2-oxo-[1,3'] bipyrrolidinyl-3-ylidenemethyl) cephems |
| US6232306B1 (en) * | 1998-06-15 | 2001-05-15 | Hoffmann-La Roche Inc. | Derivatives of 3-(2-oxo-[1,3′]bipyrrolidinyl-3-ylidenemethyl)-cephams |
| AU1654900A (en) * | 1998-12-03 | 2000-06-19 | F. Hoffmann-La Roche Ag | Bi-pyrrolidinylvinl (carba) cephalosporins |
| US6384214B1 (en) | 1999-07-05 | 2002-05-07 | Basilea Pharmaceutica Ag | Process for producing cephalosporin derivatives |
| WO2001004127A1 (en) * | 1999-07-07 | 2001-01-18 | F. Hoffmann-La Roche Ag | Vinylpyrrolidinone derivatives with substituted thiazole ring |
| DE60123513T2 (de) | 2000-04-19 | 2007-05-10 | Basilea Pharmaceutica Ag | Verfahren zur Herstellung von D-Asparaginderivaten |
| US6504025B2 (en) * | 2000-05-24 | 2003-01-07 | Basilea Pharmaceutica Ag | Process for the preparation of vinyl-pyrrolidinone cephalosporin derivatives |
| CA2418970C (en) * | 2000-08-14 | 2011-03-22 | Basilea Pharmaceutica Ag | Preparation of n-protected-3-pyrrolidine-lactam substituted phosphonium salts |
| ITMI20012363A1 (it) * | 2001-11-09 | 2003-05-09 | Antibioticos Spa | Metodo per la sintesi di catene laterali di cefalosporine |
| WO2004085444A1 (en) | 2003-03-27 | 2004-10-07 | Basilea Pharmaceutica Ag | Cephalosporin in crystalline form |
| EP2308562B1 (en) * | 2003-12-25 | 2015-02-25 | Ono Pharmaceutical Co., Ltd. | Azetidine ring compounds and drugs comprising the same |
| US7569691B2 (en) * | 2005-04-20 | 2009-08-04 | Shin-Etsu Chemical Co., Ltd. | Protected piperazino group-bearing organoxysilane compound and making method |
| CN101245079B (zh) * | 2007-02-14 | 2010-07-07 | 山东轩竹医药科技有限公司 | 头孢抗生素衍生物 |
| CN101245077B (zh) * | 2007-02-14 | 2010-06-02 | 山东轩竹医药科技有限公司 | 头孢菌素衍生物 |
| KR20100093532A (ko) | 2007-10-25 | 2010-08-25 | 아카오젠, 인코포레이티드 | 카바세펨 β―락탐 항생제 |
| AR071318A1 (es) | 2008-04-15 | 2010-06-09 | Basilea Pharmaceutica Ag | Benzhidril ester del acido (6r,7r)-7-{2-(5-amino-[1,2,4]tiadiazol-3-il)-2-[(z)-tritiloxiimino]-acetilamino}-3-[(r)-1'-terc-butoxicarbonil-2-oxo-[1,3']bipirrolidinil-(3e)-ilidenometil]-8-oxo-5-tia-1-aza-biciclo[4.2.0]oct-2-eno-2-carboxilico cristalino; su elaboracion y uso |
| WO2010030810A1 (en) * | 2008-09-10 | 2010-03-18 | Achaogen, Inc. | Carbacephem beta-lactam antibiotics |
| WO2010072672A1 (en) | 2008-12-24 | 2010-07-01 | Basilea Pharmaceutica Ag | New crystal polymorphs of ceftobiprole |
| CN101899059B (zh) * | 2009-01-21 | 2012-02-15 | 山东轩竹医药科技有限公司 | 含有吡咯烷并环的头孢菌素衍生物 |
| CN102448966A (zh) * | 2009-05-25 | 2012-05-09 | 桑多斯股份公司 | 生产头孢托罗酯的方法 |
| CN102030766B (zh) * | 2009-09-30 | 2012-08-08 | 山东轩竹医药科技有限公司 | 含有二氢吡咯并杂环的头孢抗生素 |
| CN103864851B (zh) * | 2014-03-25 | 2016-08-17 | 华润赛科药业有限责任公司 | 作为前药的头孢吡普衍生物及其制备方法和用途 |
| US20240131034A1 (en) | 2022-10-10 | 2024-04-25 | Basilea Pharmaceutica International Ag, Allschwil | Methods of treating staphylococcus aureus bacteremia infections |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL94946A0 (en) * | 1989-07-13 | 1991-06-10 | Eisai Co Ltd | 3-substituted vinyl cephalosporin derivatives,their preparation and pharmaceutical compositions containing them |
| KR950704331A (ko) * | 1992-07-12 | 1995-11-17 | 후지야마 아키라 | 세펨 화합물 및 그의 약제학적 조성물(cephem compounds and their pharmaceutical compositions) |
| US5523400A (en) * | 1993-04-16 | 1996-06-04 | Hoffmann-La Roche Inc. | Cephalosporin antibiotics |
| PT620225E (pt) * | 1993-04-16 | 2003-03-31 | Basilea Pharmaceutica Ag | Derivados de cefalosporina |
| US5827845A (en) * | 1993-09-29 | 1998-10-27 | Meiji Seika Kaisha, Ltd. | Cephalosporin derivative |
| JPH08319291A (ja) * | 1995-05-25 | 1996-12-03 | Meiji Seika Kaisha Ltd | 新規セフェム誘導体 |
| AT403161B (de) * | 1995-07-19 | 1997-11-25 | Biochemie Gmbh | Verfahren zur herstellung von cephemverbindungen |
-
1997
- 1997-12-01 TW TW086118048A patent/TW415949B/zh not_active IP Right Cessation
- 1997-12-08 US US08/986,549 patent/US5981519A/en not_active Expired - Lifetime
- 1997-12-09 NZ NZ329363A patent/NZ329363A/xx unknown
- 1997-12-10 CA CA2628224A patent/CA2628224C/en not_active Expired - Lifetime
- 1997-12-10 CA CA002224438A patent/CA2224438C/en not_active Expired - Lifetime
- 1997-12-11 ES ES97121833T patent/ES2179996T3/es not_active Expired - Lifetime
- 1997-12-11 EP EP97121833A patent/EP0849269B9/en not_active Expired - Lifetime
- 1997-12-11 DE DE69713865T patent/DE69713865T2/de not_active Expired - Lifetime
- 1997-12-11 AT AT97121833T patent/ATE220402T1/de active
- 1997-12-11 PT PT97121833T patent/PT849269E/pt unknown
- 1997-12-11 DK DK97121833T patent/DK0849269T3/da active
- 1997-12-15 HU HU9702474A patent/HUP9702474A3/hu unknown
- 1997-12-15 IL IL12260497A patent/IL122604A0/xx unknown
- 1997-12-16 NO NO975901A patent/NO975901L/no not_active Application Discontinuation
- 1997-12-17 KR KR1019970069917A patent/KR100395985B1/ko not_active IP Right Cessation
- 1997-12-17 CZ CZ974057A patent/CZ405797A3/cs unknown
- 1997-12-18 AU AU48463/97A patent/AU729653B2/en not_active Expired
- 1997-12-18 CN CN97120875A patent/CN1104436C/zh not_active Expired - Lifetime
- 1997-12-18 MA MA24904A patent/MA26457A1/fr unknown
- 1997-12-18 CN CNB001337637A patent/CN1183141C/zh not_active Expired - Lifetime
- 1997-12-18 CN CNB001337629A patent/CN1163496C/zh not_active Expired - Lifetime
- 1997-12-19 JP JP35041397A patent/JP3264877B2/ja not_active Expired - Lifetime
-
2000
- 2000-11-03 CN CNB001337645A patent/CN1198833C/zh not_active Expired - Lifetime
- 2000-11-03 CN CN00133761A patent/CN1132833C/zh not_active Expired - Lifetime
-
2001
- 2001-03-29 KR KR1020010016369A patent/KR100310384B1/ko not_active IP Right Cessation
- 2001-03-29 KR KR1020010016370A patent/KR100331212B1/ko not_active IP Right Cessation
- 2001-05-28 JP JP2001158260A patent/JP4043203B2/ja not_active Expired - Fee Related
-
2003
- 2003-12-31 CY CY0300097A patent/CY2400B1/xx unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NO975901L (no) | Vinyl-pyrrolidinon cefalosporiner med basiske substituenter | |
| AU1025795A (en) | Prolineamide derivatives | |
| CA2030433A1 (en) | New isoquinoline- carboxamide amino acid derivatives useful for treatment of viral diseases | |
| AU5669298A (en) | Cyclosporin derivatives, their preparation and pharmaceutical compositions containing them | |
| NO20004624D0 (no) | Benzensulfonamid-derivater og deres anvendelse som medikamenter | |
| AP9801378A0 (en) | 9-amino-3- keto erythromycin derivatives. | |
| NO331002B1 (no) | Tioxantinderivater og farmasoytiske preparater med tioxantinderivater | |
| HUP0001269A2 (hu) | 2-Oxo-1-azetidin-szulfonsav-származékok és ezeket tartalmazó kombinált gyógyszerkészítmények | |
| TW375615B (en) | Galanthamine derivatives and their use as medicaments | |
| NZ237351A (en) | Cephalosporin derivative, medicaments, intermediate compound | |
| ES2052015T3 (es) | Un metodo de preparacion de una composicion farmaceutica. | |
| DE69302646D1 (de) | Benzimidazolverbindungen als Antibiotika gegen Campylobacter pylon | |
| MY135646A (en) | Indolyl derivatives | |
| HU893127D0 (en) | Process for the preparation of novel spiro-(imidazolidino-naphtaline) derivatives and pharmaceutical compositions containing such compounds as active ingredient | |
| NZ332687A (en) | use of 1-methyl-carbapenem derivatives as anti-helicobacter pylori agents | |
| AP9801235A0 (en) | Erythromycin derivatives. | |
| WO2001017955A3 (en) | Hydroxyacetamidobenzenesulphonamide derivatives | |
| NO20013601L (no) | Nye morfolinobenzamidsalter | |
| AU658175B2 (en) | Use of 2-iminothiazolidin-4-one derivatives as novel pharmaceutical active ingredients | |
| DE69429447D1 (de) | Verwendung von 2-aminopurinderivaten zur behandlung und prophylaxe der menschlichen herpesvirus 7 infektionen | |
| YU38497A (sh) | Derivati 1-karba-(detia)-cefalosporina, njihova proizvodnja, intermedijeri koji se koriste u toj proizvodnji, odgovarajući farmaceutski preparati i upotreba jedinjenja za proizvodnju farmaceutskih preparata | |
| MXPA99003849A (es) | Derivados 9a, 11b-deshidro de 9-oxima-3-ceto-6-0-metileritromicina. | |
| SE8900725L (sv) | Indolfoereningar och framstaellning daerav | |
| GEP19980890B (en) | Derivatives of N1-(1,2-Cis-halogeno¬-cyclopropyl) Substituted Pyridonecarbonic Acid | |
| KR890001561A (ko) | 세균감염 치료용 약제학적 제제 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |