YU38497A - Derivati 1-karba-(detia)-cefalosporina, njihova proizvodnja, intermedijeri koji se koriste u toj proizvodnji, odgovarajući farmaceutski preparati i upotreba jedinjenja za proizvodnju farmaceutskih preparata - Google Patents

Derivati 1-karba-(detia)-cefalosporina, njihova proizvodnja, intermedijeri koji se koriste u toj proizvodnji, odgovarajući farmaceutski preparati i upotreba jedinjenja za proizvodnju farmaceutskih preparata

Info

Publication number
YU38497A
YU38497A YU38497A YU38497A YU38497A YU 38497 A YU38497 A YU 38497A YU 38497 A YU38497 A YU 38497A YU 38497 A YU38497 A YU 38497A YU 38497 A YU38497 A YU 38497A
Authority
YU
Yugoslavia
Prior art keywords
pharmaceutical preparations
compounds
preparation
cefalosporine
detia
Prior art date
Application number
YU38497A
Other languages
English (en)
Inventor
Peter Angehrn
Paul Hebeisen
Ingrid Krauss-Heinze
Malcolm Page
Original Assignee
F. Hoffmann - La Roche Ag.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F. Hoffmann - La Roche Ag. filed Critical F. Hoffmann - La Roche Ag.
Publication of YU38497A publication Critical patent/YU38497A/sh

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D463/00Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D463/10Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D463/14Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
    • C07D463/16Nitrogen atoms
    • C07D463/18Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
    • C07D463/20Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D463/22Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen further substituted by nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Jedinjenja formule I u kojoj X predstavlja CH ili N a simboli R1, R2, R3, R, Q i n su definisani kao u opisu, kao i njihovi estri koji se lako hidrolizuju, farmaceutski prihvatljive soli pomenutih jedinjenja i hidrati jedinjenja formule I i njihovih estara i soli; postupak za proizvodnju tih jedinjenja; intermedijeri u postupku za proizvodnju tih jedinjenja; farmaceutski preparati koji sadrže ta jedinjenja za lečenje i profilaksu infektivnih bolesti; kao i upotreba jedinjenja za proizvodnju farmaceutskih preparata.
YU38497A 1996-09-23 1997-09-18 Derivati 1-karba-(detia)-cefalosporina, njihova proizvodnja, intermedijeri koji se koriste u toj proizvodnji, odgovarajući farmaceutski preparati i upotreba jedinjenja za proizvodnju farmaceutskih preparata YU38497A (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP96115210 1996-09-23

Publications (1)

Publication Number Publication Date
YU38497A true YU38497A (sh) 1999-12-27

Family

ID=8223209

Family Applications (1)

Application Number Title Priority Date Filing Date
YU38497A YU38497A (sh) 1996-09-23 1997-09-18 Derivati 1-karba-(detia)-cefalosporina, njihova proizvodnja, intermedijeri koji se koriste u toj proizvodnji, odgovarajući farmaceutski preparati i upotreba jedinjenja za proizvodnju farmaceutskih preparata

Country Status (23)

Country Link
US (1) US5939410A (sh)
JP (1) JPH10101670A (sh)
KR (1) KR100256473B1 (sh)
CN (1) CN1184110A (sh)
AR (1) AR008450A1 (sh)
AU (1) AU723176B2 (sh)
BR (1) BR9704770A (sh)
CA (1) CA2216222A1 (sh)
CO (1) CO4900072A1 (sh)
CZ (1) CZ292097A3 (sh)
HR (1) HRP970511A2 (sh)
HU (1) HUP9701548A3 (sh)
ID (1) ID18323A (sh)
IL (1) IL121798A0 (sh)
MA (1) MA26442A1 (sh)
NO (1) NO974366L (sh)
NZ (1) NZ328595A (sh)
PE (1) PE110098A1 (sh)
PL (1) PL322240A1 (sh)
SG (1) SG53049A1 (sh)
TR (1) TR199701011A2 (sh)
YU (1) YU38497A (sh)
ZA (1) ZA978332B (sh)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101835777A (zh) * 2007-10-25 2010-09-15 尔察祯有限公司 碳头孢烯β-内酰胺抗生素
WO2010030810A1 (en) * 2008-09-10 2010-03-18 Achaogen, Inc. Carbacephem beta-lactam antibiotics

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0112481A1 (en) * 1982-11-12 1984-07-04 Kyowa Hakko Kogyo Co., Ltd Beta-lactam compound
GB9213567D0 (en) * 1992-06-26 1992-08-12 Smithkline Beecham Plc Novel compounds
PT620225E (pt) * 1993-04-16 2003-03-31 Basilea Pharmaceutica Ag Derivados de cefalosporina
WO1996026943A1 (en) * 1995-02-27 1996-09-06 F.Hoffmann-La Roche Ag Derivatives of 3-pyrrolidylidene-2-one-cephalosporines
EP0761673A1 (en) * 1995-09-12 1997-03-12 F. Hoffmann-La Roche Ag Cephalosporin derivatives

Also Published As

Publication number Publication date
CN1184110A (zh) 1998-06-10
ZA978332B (en) 1998-03-23
CA2216222A1 (en) 1998-03-23
AU723176B2 (en) 2000-08-17
BR9704770A (pt) 1998-11-03
HUP9701548A3 (en) 2001-04-28
HRP970511A2 (en) 1998-08-31
NO974366L (no) 1998-03-24
US5939410A (en) 1999-08-17
AR008450A1 (es) 2000-01-19
IL121798A0 (en) 1998-02-22
JPH10101670A (ja) 1998-04-21
KR100256473B1 (ko) 2000-05-15
NZ328595A (en) 1999-01-28
CZ292097A3 (cs) 1998-04-15
PL322240A1 (en) 1998-03-30
HU9701548D0 (en) 1997-11-28
HUP9701548A2 (hu) 1999-05-28
CO4900072A1 (es) 2000-03-27
SG53049A1 (en) 1998-09-28
AU3838297A (en) 1998-01-15
MX9707201A (es) 1998-06-28
ID18323A (id) 1998-03-26
PE110098A1 (es) 1999-01-13
KR19980024863A (ko) 1998-07-06
TR199701011A2 (xx) 1998-04-21
NO974366D0 (no) 1997-09-22
MA26442A1 (fr) 2004-12-20

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YU38497A (sh) Derivati 1-karba-(detia)-cefalosporina, njihova proizvodnja, intermedijeri koji se koriste u toj proizvodnji, odgovarajući farmaceutski preparati i upotreba jedinjenja za proizvodnju farmaceutskih preparata
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