HUP9801925A1 - Nátrium/hidrogén-csere inhibítorok alkalmazása protozoák által okozott betegségek kezelésére alkalmas gyógyszerkészítmények előállítására - Google Patents

Nátrium/hidrogén-csere inhibítorok alkalmazása protozoák által okozott betegségek kezelésére alkalmas gyógyszerkészítmények előállítására

Info

Publication number
HUP9801925A1
HUP9801925A1 HU9801925A HUP9801925A HUP9801925A1 HU P9801925 A1 HUP9801925 A1 HU P9801925A1 HU 9801925 A HU9801925 A HU 9801925A HU P9801925 A HUP9801925 A HU P9801925A HU P9801925 A1 HUP9801925 A1 HU P9801925A1
Authority
HU
Hungary
Prior art keywords
sodium
inhibitors
hydrogen
diseases caused
protozoons
Prior art date
Application number
HU9801925A
Other languages
English (en)
Inventor
Hans Jochen Lang
Michael Lanzer
Cecilia Sanchez
Jochen Wiesner
Stefan Wünsch
Original Assignee
Hoechst Marion Roussel Deutschland Gmbh.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel Deutschland Gmbh. filed Critical Hoechst Marion Roussel Deutschland Gmbh.
Publication of HU9801925D0 publication Critical patent/HU9801925D0/hu
Publication of HUP9801925A1 publication Critical patent/HUP9801925A1/hu
Publication of HUP9801925A3 publication Critical patent/HUP9801925A3/hu
Publication of HU225583B1 publication Critical patent/HU225583B1/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pyrrole Compounds (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

A találmány tárgya nátriűm/hidrőgén-csere inhibitőrők alkalmazásaprőtőzőák által őkőzőtt betegségek kezelésére vagy megelőzésérealkalmas gyógyszerkészítmények előállítására. A találmány értelmébennátriűm/hidrőgén-csere inhibitőrként előnyösen alkalmazhatók különbözőbezőilgűanidinszármazékők. ŕ
HU9801925A 1997-08-28 1998-08-26 Use of sodium-hydrogen-exchange-inhibitors for producing pharmaceutical compositions treating diseases caused by protozoons HU225583B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19737463A DE19737463A1 (de) 1997-08-28 1997-08-28 Verwendung von Inhibitoren des Natrium-Wasserstoff-Austauschers zur Herstellung eines Arzneimittels zur Behandlung von Erkrankungen, die durch Protozoen verursacht werden

Publications (4)

Publication Number Publication Date
HU9801925D0 HU9801925D0 (en) 1998-10-28
HUP9801925A1 true HUP9801925A1 (hu) 2000-02-28
HUP9801925A3 HUP9801925A3 (en) 2004-11-29
HU225583B1 HU225583B1 (en) 2007-03-28

Family

ID=7840411

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9801925A HU225583B1 (en) 1997-08-28 1998-08-26 Use of sodium-hydrogen-exchange-inhibitors for producing pharmaceutical compositions treating diseases caused by protozoons

Country Status (26)

Country Link
US (1) US6114393A (hu)
EP (1) EP0901788A3 (hu)
JP (1) JPH11171792A (hu)
KR (1) KR100567144B1 (hu)
CN (1) CN1244322C (hu)
AR (1) AR013949A1 (hu)
AU (1) AU738599B2 (hu)
BR (1) BR9803243A (hu)
CA (1) CA2246407A1 (hu)
CZ (1) CZ296815B6 (hu)
DE (1) DE19737463A1 (hu)
HK (1) HK1018589A1 (hu)
HR (1) HRP980468A2 (hu)
HU (1) HU225583B1 (hu)
ID (1) ID20794A (hu)
IL (1) IL125946A0 (hu)
MY (1) MY137406A (hu)
NO (1) NO320368B1 (hu)
NZ (1) NZ331566A (hu)
PL (1) PL191267B1 (hu)
RU (1) RU2225726C2 (hu)
SG (1) SG74074A1 (hu)
SK (1) SK285457B6 (hu)
TR (1) TR199801669A2 (hu)
TW (1) TW592690B (hu)
ZA (1) ZA987781B (hu)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9224739D0 (en) * 1992-11-26 1993-01-13 Wellcome Found Medicaments
JP4100910B2 (ja) * 1999-12-23 2008-06-11 ファイザー・プロダクツ・インク ヒドロゲル駆動の薬物剤形
US7375138B2 (en) * 2002-05-18 2008-05-20 Sanofi-Aventis Deutschland Gmbh Pentafluorosulfanylbenzoylguanidines, processes for their preparation, their use as medicaments or diagnostic aids, and medicaments comprising them
FR2840302B1 (fr) * 2002-06-03 2004-07-16 Aventis Pharma Sa Derives d'isoindolones, procede de preparation et intermediaire de ce procede a titre de medicaments et compositions pharmaceutiques les renfermant
US6878748B2 (en) 2002-06-13 2005-04-12 Aventis Pharma Deutschland Gmbh Fluorinated cycloalkyl-derivatized benzoylguanidines, process for their preparation, their uses as medicament, and medicament containing them
ES2894657T3 (es) * 2017-07-04 2022-02-15 Sanofi Sa Compuestos de etinilo, su preparación y su uso terapéutico para el tratamiento de la malaria

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1336871A (en) * 1970-01-02 1973-11-14 Wellcome Found Method for preparing biologically active substituted amidines
US4032655A (en) * 1974-05-15 1977-06-28 Bayer Aktiengesellschaft Phenylguanidines useful as anthelmintic agents
US4088780A (en) * 1974-05-15 1978-05-09 Bayer Aktiengesellschaft Substituted phenylguanidines and processes for their preparation and use
US4544670A (en) * 1982-08-24 1985-10-01 William H. Rorer, Inc. Method of treating coccidiosis with acyl guanidines
DE3929582A1 (de) * 1989-09-06 1991-03-07 Hoechst Ag Benzoylguanidine, verfahren zu ihrer herstellung, ihre verwendung als medikament sowie sie enthaltendes medikament
IN172842B (hu) * 1990-05-17 1993-12-11 Boots Pharmaceuticals Limited
AU3141693A (en) * 1991-11-22 1993-06-15 Friedman, Mark M. Non-peptidic surrogates of the arg-gly-asp sequence and pharmaceutical compositions comprising them
CZ284456B6 (cs) * 1992-02-15 1998-12-16 Hoechst Aktiengesellschaft Aminosubstituované benzoylguanidiny, způsob jejich přípravy, jejich použití jako léčiv a léčivo, které je obsahuje
GB9224739D0 (en) * 1992-11-26 1993-01-13 Wellcome Found Medicaments
DE4318658A1 (de) * 1993-06-04 1994-12-08 Hoechst Ag Substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE4318756A1 (de) * 1993-06-05 1994-12-08 Hoechst Ag Substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE19502644A1 (de) * 1995-01-28 1996-08-01 Merck Patent Gmbh 4-Amino-benzoylguanidin-Derivate
FR2734263B1 (fr) * 1995-05-17 1997-06-20 Fournier Ind & Sante Analogues de la 15-deoxyspergualine, leur procede de preparation et leur utilisation en therapeutique
DK0832094T3 (da) * 1995-06-07 2004-05-17 Genaera Corp Aminosterolforbindelser, som er nyttige som inhibitorer for natrium/proton-omskifteren (NHE), farmaceutiske fremgangsmåder og sammensætninger, som anvender sådanne inhibitorer, og fremgangsmåder til vurdering af den NHE-inhiberende effektivitet af for..
DE19542306A1 (de) * 1995-11-14 1997-05-15 Hoechst Ag Sulfonylamino-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament

Also Published As

Publication number Publication date
NZ331566A (en) 2001-03-30
PL191267B1 (pl) 2006-04-28
PL328265A1 (en) 1999-03-01
HRP980468A2 (en) 1999-06-30
HK1018589A1 (en) 1999-12-30
CN1244322C (zh) 2006-03-08
ID20794A (id) 1999-03-04
ZA987781B (en) 1999-05-27
NO983943D0 (no) 1998-08-27
HU9801925D0 (en) 1998-10-28
NO320368B1 (no) 2005-11-28
DE19737463A1 (de) 1999-03-04
RU2225726C2 (ru) 2004-03-20
SK285457B6 (sk) 2007-02-01
BR9803243A (pt) 2000-03-21
US6114393A (en) 2000-09-05
TW592690B (en) 2004-06-21
IL125946A0 (en) 1999-04-11
SK117498A3 (en) 1999-03-12
CZ296815B6 (cs) 2006-06-14
TR199801669A3 (tr) 1999-03-22
CA2246407A1 (en) 1999-02-28
KR19990023905A (ko) 1999-03-25
HUP9801925A3 (en) 2004-11-29
CN1209994A (zh) 1999-03-10
EP0901788A3 (de) 2004-01-02
AR013949A1 (es) 2001-01-31
JPH11171792A (ja) 1999-06-29
MY137406A (en) 2009-01-30
HU225583B1 (en) 2007-03-28
SG74074A1 (en) 2000-07-18
KR100567144B1 (ko) 2006-11-30
TR199801669A2 (xx) 1999-03-22
NO983943L (no) 1999-03-01
CZ272998A3 (cs) 1999-03-17
AU738599B2 (en) 2001-09-20
EP0901788A2 (de) 1999-03-17
AU8189498A (en) 1999-03-11

Similar Documents

Publication Publication Date Title
MX9604378A (es) Amidas de acido quinolin-2-carboxilico sustituidas, su preparacion y su empleo como medicamentos, asi como productos intermedios.
UA74346C2 (uk) Похідні амінодикарбонових кислот, їх застосування та лікарський засіб
ATE365720T1 (de) Agonisten von beta-adrenorezeptoren
YU21702A (sh) Supstituisani indoli za moduliranje nfkb aktivnosti
AP2088A (en) Phenethanolamine derivatives for treatment of respiratory diseases
MXPA02007942A (es) Derivados de pirrolopirimidinona, procesos de preparacion y uso.
YU56995A (sh) Soli derivata indola
NO20012158L (no) Substituerte 2-fenylbenzimidazoler, fremgangsmåte til fremstilling og anvendelse derav
BR9713465A (pt) Inibidores metalotprotease de amina cìclica sibstituìda
MXPA04002405A (es) Derivados de fenetanolamina para tratamiento de enfermedades respiratorias.
ATE388951T1 (de) Dpp-iv-inhibierende purin-derivative zur behandlung von diabetes
GB0112348D0 (en) Compounds
MX9503529A (es) Derivados de glicinamida, procedimiento para su preparacion y medicamentos que los contienen.
MXPA04005886A (es) Derivados de azaindolilalquilamina como ligandos de 5-hidroxitirptamina-6.
BR0115936A (pt) 2-anilino-benzimidazóis substituìdos e sua aplicação como inibidores de nhe
BR0206935A (pt) Composto, formulação farmacêutica, uso de um composto, método de tratamento e/ou profilaxia de condições associadas com a inibição da glicogênio sintase quinase-3, e, processo para a preparação de um composto
YU94103A (sh) Novi derivati sulfonske kiseline
HUP0004282A2 (hu) 2-Halogén-6-0-szubsztituált ketolidszármazékok
UA49884C2 (uk) ПОХІДНІ <font face="Symbol">a</font>-ГІДРОКСИКАРБОНОВОЇ КИСЛОТИ ТА ЛІКАРСЬКИЙ ЗАСІБ НА ЇХ ОСНОВІ
SE9903894D0 (sv) Novel compounds
UA83821C2 (ru) Производные бензолсульфонамидов, способ их получения и их применение для лечения воспалительных заболеваний и утоления боли
CA2266759A1 (en) 3-mercaptoacetylamino-1,5-substituted-2-oxo-azepan derivatives useful as inhibitors of matrix metalloproteinase
DE69819539D1 (de) Antithrombotische mittel
BR0113461A (pt) Compostos ou sais farmaceuticamente aceitáveis, composições farmacêuticas, método de tratamento de doença ou condição mediada por erab, hadh2 ou (beta)-amilóide em mamìferos, métodos de inibição ou modulação da atividade enzimática de erab ou hadh2 e método de tratamento de mal de alzheimer ou demência em mamìferos
HUP9801925A1 (hu) Nátrium/hidrogén-csere inhibítorok alkalmazása protozoák által okozott betegségek kezelésére alkalmas gyógyszerkészítmények előállítására

Legal Events

Date Code Title Description
MM4A Lapse of definitive patent protection due to non-payment of fees