NO934195L - Substituerte 3-aminokinuklidiner - Google Patents

Substituerte 3-aminokinuklidiner

Info

Publication number
NO934195L
NO934195L NO934195A NO934195A NO934195L NO 934195 L NO934195 L NO 934195L NO 934195 A NO934195 A NO 934195A NO 934195 A NO934195 A NO 934195A NO 934195 L NO934195 L NO 934195L
Authority
NO
Norway
Prior art keywords
compounds
aminoquinuclidines
substituted
disorders
antagonists
Prior art date
Application number
NO934195A
Other languages
English (en)
Other versions
NO305173B1 (no
NO934195D0 (no
Inventor
Fumitaka Ito
Toshihide Kokura
Masami Nakane
Kunio Satake
Hiroaki Wakabayashi
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of NO934195D0 publication Critical patent/NO934195D0/no
Publication of NO934195L publication Critical patent/NO934195L/no
Publication of NO305173B1 publication Critical patent/NO305173B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Medicinal Preparation (AREA)
NO934195A 1991-05-22 1993-11-19 Substituerte 3-aminokinuklidiner NO305173B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP14682691 1991-05-22
PCT/US1992/004002 WO1992020676A1 (en) 1991-05-22 1992-05-19 Substituted 3-aminoquinuclidines

Publications (3)

Publication Number Publication Date
NO934195D0 NO934195D0 (no) 1993-11-19
NO934195L true NO934195L (no) 1993-11-19
NO305173B1 NO305173B1 (no) 1999-04-12

Family

ID=15416402

Family Applications (1)

Application Number Title Priority Date Filing Date
NO934195A NO305173B1 (no) 1991-05-22 1993-11-19 Substituerte 3-aminokinuklidiner

Country Status (25)

Country Link
EP (1) EP0585328B1 (no)
KR (1) KR100246065B1 (no)
CN (1) CN1041827C (no)
AT (1) ATE211743T1 (no)
AU (1) AU658898B2 (no)
BR (1) BR9206044A (no)
CA (1) CA2109415C (no)
CZ (1) CZ247993A3 (no)
DE (2) DE69232334T2 (no)
DK (1) DK0585328T3 (no)
EG (1) EG20218A (no)
ES (1) ES2168260T3 (no)
FI (1) FI935134A (no)
HU (1) HUT65771A (no)
IE (1) IE921662A1 (no)
IL (1) IL101960A (no)
MX (1) MX9202449A (no)
NO (1) NO305173B1 (no)
NZ (2) NZ272941A (no)
PL (4) PL170513B1 (no)
PT (1) PT100514B (no)
RU (1) RU2092486C1 (no)
UA (1) UA26401C2 (no)
WO (1) WO1992020676A1 (no)
ZA (1) ZA923773B (no)

Families Citing this family (69)

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US5138060A (en) * 1991-01-03 1992-08-11 Pfizer Inc. Process and intermediates for preparing azabicyclo(2.2.2)octan-3-imines
UA39168C2 (uk) * 1991-06-20 2001-06-15 Пфайзер, Інк. Фторалкоксифенільні похідні піперидину або хінуклідину, що є антагоністами речовини p і фармацевтична композиція на їх основі
JP2656702B2 (ja) * 1992-03-23 1997-09-24 ファイザー製薬株式会社 ペプチド性キヌクリジン
AU4224993A (en) * 1992-08-19 1994-03-15 Pfizer Inc. Substituted benzylamino nitrogen containing non-aromatic heterocycles
JP2656699B2 (ja) * 1992-10-21 1997-09-24 ファイザー製薬株式会社 置換ベンジルアミノキヌクリジン
US5837711A (en) * 1992-10-28 1998-11-17 Pfizer Inc. Substituted quinuclidines as substance P antagonists
JP2656700B2 (ja) * 1992-10-28 1997-09-24 ファイザー製薬株式会社 置換キヌクリジン誘導体
DE69328975T2 (de) * 1992-12-10 2000-11-09 Pfizer Inc., New York Aminomethylen substituierte heterocyclische verbindungen und ihre verwendung alssubstanz p antagonisten
JP2822274B2 (ja) * 1993-05-19 1998-11-11 ファイザー製薬株式会社 Ｐ物質拮抗剤としてのヘテロ原子置換アルキルベンジルアミノキヌクリジン類
IL109646A0 (en) * 1993-05-19 1994-08-26 Pfizer Heteroatom substituted alkyl benzylamino-quinuclidines
US5393762A (en) * 1993-06-04 1995-02-28 Pfizer Inc. Pharmaceutical agents for treatment of emesis
DE69413822T2 (de) * 1993-07-15 1999-02-25 Pfizer Inc., New York, N.Y. Benzyloxychinuclidine als substanz p antagonisten
DE69433744T2 (de) * 1993-09-17 2004-10-14 Pfizer Inc. 3-amino-5-carboxy-substituierte piperidine und 3-amino-4-carboxy-substituierte pyrrolidine als tachykinin-antagonisten
US6083943A (en) * 1993-09-17 2000-07-04 Pfizer Inc Substituted azaheterocyclecarboxylic acid
EP0653208A3 (en) * 1993-11-17 1995-10-11 Pfizer Substance P antagonists for the treatment or prevention of sunburn.
EP0659409A3 (en) * 1993-11-23 1995-08-09 Pfizer Substance P antagonists for the inhibition of angiogenesis.
EP0655246A1 (en) * 1993-11-30 1995-05-31 Pfizer Inc. Substance P antagonists for the treatment of disorders caused by helicobacter pylori or other spiral urease-positive gram-negative bacteria
FR2728165A1 (fr) 1994-12-19 1996-06-21 Oreal Utilisation d'un antagoniste de substance p pour le traitement des rougeurs cutanees d'origine neurogene
FR2728169A1 (fr) 1994-12-19 1996-06-21 Oreal Utilisation d'un antagoniste de substance p pour le traitement des prurits et des dysesthesies oculaires ou palpebrales
FR2728166A1 (fr) 1994-12-19 1996-06-21 Oreal Composition topique contenant un antagoniste de substance p
PE8798A1 (es) * 1995-07-17 1998-03-02 Pfizer Procedimiento de separacion de los enantiomeros del 1-azabiciclo[2.2.2] octan-3-amina, 2-(difenilmetil) -n- [[2-metoxi-5-(1-metiletil) fenil] metil]
TW458774B (en) 1995-10-20 2001-10-11 Pfizer Antiemetic pharmaceutical compositions
FR2741262B1 (fr) 1995-11-20 1999-03-05 Oreal Utilisation d'un antagoniste de tnf-alpha pour le traitement des rougeurs cutanees d'origine neurogene
MX9706944A (es) * 1996-09-12 1998-08-30 Pfizer Quinuclidinas sustituidas con tetrazolilo como antagonistas de la sustancia p.
NZ329807A (en) * 1997-04-23 2000-07-28 Pfizer NK-1 receptor antagonists and P receptor antagonists 2-Diarylmethyl-3-amino-1-azabicyclo[2.2.2]octane derivatives and amino substituted N-containing rings as agents for treating irritable bowel syndrome
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US7163949B1 (en) 1999-11-03 2007-01-16 Amr Technology, Inc. 4-phenyl substituted tetrahydroisoquinolines and use thereof
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US6861526B2 (en) * 2002-10-16 2005-03-01 Pfizer Inc. Process for the preparation of (S,S)-cis-2-benzhydryl-3-benzylaminoquinuclidine
NZ552397A (en) 2004-07-15 2011-04-29 Amr Technology Inc Aryl-and heteroaryl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
ATE550019T1 (de) 2005-05-17 2012-04-15 Merck Sharp & Dohme Cis-4-ä(4-chlorophenyl)sulfonylü-4-(2,5- difluorophenyl)cyclohexanepropansäure zur behandlug von krebs
KR101589551B1 (ko) 2005-07-15 2016-02-02 알바니 몰레큘라 리써치, 인크. 아릴- 및 헤테로아릴-치환된 테트라히드로벤자제핀, 및 노르에피네프린, 도파민 및 세로토닌의 재흡수를 차단하기 위한 용도
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US20110218176A1 (en) 2006-11-01 2011-09-08 Barbara Brooke Jennings-Spring Compounds, methods, and treatments for abnormal signaling pathways for prenatal and postnatal development
PL2109608T3 (pl) 2007-01-10 2011-08-31 Msd Italia Srl Indazole podstawione grupą amidową jako inhibitory polimerazy poli(ADP-rybozy)-(PARP)
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CA2682727C (en) 2007-04-02 2016-03-22 Banyu Pharmaceutical Co., Ltd. Indoledione derivative
CA2690191C (en) 2007-06-27 2015-07-28 Merck Sharp & Dohme Corp. 4-carboxybenzylamino derivatives as histone deacetylase inhibitors
KR20100126467A (ko) 2008-03-03 2010-12-01 타이거 파마테크 티로신 키나아제 억제제
US9156812B2 (en) 2008-06-04 2015-10-13 Bristol-Myers Squibb Company Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine
UA105182C2 (ru) 2008-07-03 2014-04-25 Ньюрексон, Інк. Бензоксазины, бензотиазины и родственные соединения, которые имеют ингибирующую nos активность
WO2010114780A1 (en) 2009-04-01 2010-10-07 Merck Sharp & Dohme Corp. Inhibitors of akt activity
US8802696B2 (en) 2009-05-12 2014-08-12 Albany Molecular Research, Inc. 7-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroisoqu inoli and use thereof
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BR112012008849A2 (pt) 2009-10-14 2015-09-22 Schering Corp composto, composição farmacêutica, e, uso de um composto
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CN103068980B (zh) 2010-08-02 2017-04-05 瑟纳治疗公司 使用短干扰核酸（siNA）的RNA干扰介导的联蛋白（钙粘蛋白关联蛋白质），β1（CTNNB1）基因表达的抑制
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Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990005525A1 (en) * 1988-11-23 1990-05-31 Pfizer Inc. Quinuclidine derivatives as substance p antagonists

Also Published As

Publication number Publication date
CN1068571A (zh) 1993-02-03
UA26401C2 (uk) 1999-08-30
DE9290057U1 (de) 1994-01-05
HUT65771A (en) 1994-07-28
ZA923773B (en) 1993-11-22
MX9202449A (es) 1993-03-01
EP0585328B1 (en) 2002-01-09
PL171921B1 (pl) 1997-06-30
FI935134A0 (fi) 1993-11-19
IL101960A0 (en) 1994-04-12
NO305173B1 (no) 1999-04-12
DE69232334D1 (de) 2002-02-14
KR100246065B1 (en) 2000-04-01
EP0585328A1 (en) 1994-03-09
PL172069B1 (pl) 1997-07-31
CN1041827C (zh) 1999-01-27
FI935134A (fi) 1993-11-19
PL170513B1 (en) 1996-12-31
BR9206044A (pt) 1995-03-01
HU9303307D0 (en) 1994-03-28
ATE211743T1 (de) 2002-01-15
AU1927592A (en) 1992-12-30
ES2168260T3 (es) 2002-06-16
NZ272941A (en) 1997-05-26
EG20218A (en) 1997-11-30
NO934195D0 (no) 1993-11-19
IL101960A (en) 1999-03-12
PT100514B (pt) 1999-06-30
AU658898B2 (en) 1995-05-04
CZ247993A3 (en) 1994-07-13
DE69232334T2 (de) 2002-11-14
PL170525B1 (en) 1996-12-31
RU2092486C1 (ru) 1997-10-10
CA2109415C (en) 1998-12-29
CA2109415A1 (en) 1992-11-23
PT100514A (pt) 1993-09-30
IE921662A1 (en) 1992-12-02
DK0585328T3 (da) 2002-02-11
NZ242880A (en) 1995-10-26
WO1992020676A1 (en) 1992-11-26

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Legal Events

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MM1K Lapsed by not paying the annual fees

Free format text: LAPSED IN NOVEMBER 2001