IT1234826B
(it)
*
|
1989-01-30 |
1992-05-29 |
Alfa Wassermann Spa |
Derivati eparinici e procedimento per la loro preparazione
|
IT1237518B
(it)
*
|
1989-11-24 |
1993-06-08 |
Renato Conti |
Eparine supersolfatate
|
USRE38743E1
(en)
|
1990-06-26 |
2005-06-14 |
Aventis Pharma S.A. |
Mixtures of particular LMW heparinic polysaccharides for the prophylaxis/treatment of acute thrombotic events
|
FR2663639B1
(fr)
*
|
1990-06-26 |
1994-03-18 |
Rhone Poulenc Sante |
Melanges de polysaccharides de bas poids moleculaires procede de preparation et utilisation.
|
FR2669932B1
(fr)
*
|
1990-12-03 |
1994-07-01 |
Sanofi Sa |
Nouvel heparosane-n,o-sulfate, son procede de preparation et les compositions pharmaceutiques qui le contiennent.
|
US5280016A
(en)
*
|
1991-03-29 |
1994-01-18 |
Glycomed Incorporated |
Non-anticoagulant heparin derivatives
|
NO921495L
(no)
*
|
1991-04-16 |
1992-10-19 |
Seikagaku Kogyo Co Ltd |
Oligosakkarid og fremgangsmaate for dets fremstilling
|
SE9101155D0
(sv)
*
|
1991-04-18 |
1991-04-18 |
Kabi Pharmacia Ab |
Novel heparin derivatives
|
WO1992019249A1
(en)
*
|
1991-05-02 |
1992-11-12 |
Yeda Research And Development Co. Ltd. |
Compositions for the prevention and/or treatment of pathological processes
|
US5861382A
(en)
*
|
1992-05-01 |
1999-01-19 |
Yeda Research And Development Co. Ltd. |
Methods for regulation of active TNF-α
|
US6750207B1
(en)
|
1992-05-01 |
2004-06-15 |
Yeda Research And Development Co. Ltd. |
Compositions for the regulation of cytokine activity
|
FR2691066B1
(fr)
*
|
1992-05-15 |
1995-06-09 |
Sanofi Elf |
Utilisation de glycosaminoglycanes exogenes, de leurs analogues ainsi que de leurs fragments, fractions et derives, pour la preparation de medicaments destines au traitement de thrombopenies.
|
NZ258367A
(en)
*
|
1992-11-10 |
1997-02-24 |
Yeda Res & Dev |
Oligosaccharide compositions comprising carboxylated and/or sulphated oligosaccharides for use in regulating tnf alpha production
|
US5696100A
(en)
*
|
1992-12-22 |
1997-12-09 |
Glycomed Incorporated |
Method for controlling O-desulfation of heparin and compositions produced thereby
|
US5650389A
(en)
*
|
1993-03-01 |
1997-07-22 |
University Of Alabama At Birmingham Research Foundation |
Methods for the inhibition of complement activation
|
FR2704226B1
(fr)
*
|
1993-04-22 |
1995-07-21 |
Sanofi Elf |
3-desoxy oligosaccharides, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
|
IT1264709B1
(it)
*
|
1993-07-12 |
1996-10-04 |
Italfarmaco Spa |
Derivati eparinici ad attivita' antimetastatica
|
US5583121A
(en)
*
|
1994-01-12 |
1996-12-10 |
Michigan State University |
Non-anticoagulant chemically modified heparinoids for treating hypovolemic shock and related shock syndromes
|
US6127347A
(en)
*
|
1994-01-12 |
2000-10-03 |
Univ Michigan |
Non-anticoagulant chemically modified heparinoids for treating hypovolemic shock and related shock syndromes
|
CA2189038A1
(en)
*
|
1994-05-06 |
1995-11-09 |
Kevin R. Holme |
O-desulfated heparin derivatives, methods of making and uses thereof
|
US5639469A
(en)
*
|
1994-06-15 |
1997-06-17 |
Minnesota Mining And Manufacturing Company |
Transmucosal delivery system
|
US6001820A
(en)
*
|
1995-03-31 |
1999-12-14 |
Hamilton Civic Hospitals Research Development Inc. |
Compositions and methods for inhibiting thrombogenesis
|
DE69623840D1
(de)
*
|
1995-03-31 |
2002-10-31 |
Hamilton Civic Hospitals Res |
Zusammensetzung zur Hemmung der Thromboseentstehung
|
US5763427A
(en)
*
|
1995-03-31 |
1998-06-09 |
Hamilton Civic Hospitals Research Development Inc. |
Compositions and methods for inhibiting thrombogenesis
|
US5744457A
(en)
*
|
1995-03-31 |
1998-04-28 |
Hamilton Civic Hospitals Research Development Inc. |
Compositions and methods for inhibiting thrombogenesis
|
WO1997016556A1
(en)
|
1995-10-30 |
1997-05-09 |
Massachusetts Institute Of Technology |
Rationally designed polysaccharide lyases derived from heparinase i
|
US6491965B1
(en)
*
|
1995-11-30 |
2002-12-10 |
Hamilton Civic Hospitals Research Development, Inc. |
Medical device comprising glycosaminoglycan-antithrombin III/heparin cofactor II conjugates
|
US7045585B2
(en)
*
|
1995-11-30 |
2006-05-16 |
Hamilton Civic Hospital Research Development Inc. |
Methods of coating a device using anti-thrombin heparin
|
US6562781B1
(en)
*
|
1995-11-30 |
2003-05-13 |
Hamilton Civic Hospitals Research Development Inc. |
Glycosaminoglycan-antithrombin III/heparin cofactor II conjugates
|
US5767269A
(en)
*
|
1996-10-01 |
1998-06-16 |
Hamilton Civic Hospitals Research Development Inc. |
Processes for the preparation of low-affinity, low molecular weight heparins useful as antithrombotics
|
FR2763848B1
(fr)
|
1997-05-28 |
2000-01-28 |
Rhone Poulenc Rorer Sa |
Utilisation des heparines de bas poids moleculaire pour la prevention et le traitement du trauma du systeme nerveux central
|
CA2293595A1
(en)
*
|
1997-06-06 |
1998-12-10 |
Hamilton Civic Hospitals Research Development, Inc. |
Modified low molecular weight heparin that inhibits clot associated coagulation factors
|
CA2310422A1
(en)
*
|
1997-11-20 |
1999-06-03 |
Ikuo Yamashina |
Low-molecular heparin modification and remedy for skin ulcer
|
US6498246B1
(en)
*
|
1998-02-26 |
2002-12-24 |
Seikagaku Corporation |
Glycosaminoglycan derivatives and processes for preparing same
|
US6028061A
(en)
*
|
1998-06-18 |
2000-02-22 |
Children's Medical Center Corp |
Angiogenesis inhibitors and use thereof
|
US7056504B1
(en)
|
1998-08-27 |
2006-06-06 |
Massachusetts Institute Of Technology |
Rationally designed heparinases derived from heparinase I and II
|
EP1109919A2
(en)
*
|
1998-08-27 |
2001-06-27 |
Massachusetts Institute Of Technology |
Rationally designed heparinases derived from heparinase i and ii
|
JP4633223B2
(ja)
*
|
1999-03-31 |
2011-02-16 |
生化学工業株式会社 |
血管内皮細胞増殖因子依存性血管内皮細胞増殖の抑制剤
|
JP4824170B2
(ja)
|
1999-04-23 |
2011-11-30 |
マサチューセッツ インスティテュート オブ テクノロジー |
ポリマーを表記するためのシステムおよび方法
|
KR20020032444A
(ko)
*
|
1999-06-30 |
2002-05-03 |
잭 허쉬 |
응괴 연관된 응고 인자를 억제하는 헤파린 조성물
|
US20080139503A1
(en)
*
|
2000-01-25 |
2008-06-12 |
Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. |
Derivatives of partially desulphated glycosaminoglycans as heparanase inhibitors, endowed with antiangiogenic activity and devoid of anticoagulating effect
|
US7781416B2
(en)
*
|
2000-01-25 |
2010-08-24 |
Sigma-Tau Research Switzerland S.A. |
Derivatives of partially desulphated glycosaminoglycans as heparanase inhibitors, endowed with antiangiogenic activity and devoid of anticoagulating effect
|
IT1316986B1
(it)
*
|
2000-01-25 |
2003-05-26 |
Sigma Tau Ind Farmaceuti |
Derivati glicosamminoglicani parzialmente desolfatati nonanticoagulanti ad attivita' antiangiogenica.
|
CA2402160C
(en)
*
|
2000-03-08 |
2012-02-14 |
Massachusetts Institute Of Technology |
Heparinase iii and uses thereof
|
JP4633233B2
(ja)
*
|
2000-06-29 |
2011-02-16 |
生化学工業株式会社 |
クラミジア感染症処置剤
|
CA2420890A1
(en)
*
|
2000-09-08 |
2002-03-14 |
Hamilton Civic Hospitals Research Development, Inc. |
Antithrombotic compositions
|
DE60138115D1
(de)
*
|
2000-09-12 |
2009-05-07 |
Massachusetts Inst Technology |
Verfahren und produkte, die mit niedermolekularem heparin assoziiert sind
|
AU2002224408B2
(en)
*
|
2000-10-18 |
2007-08-23 |
Massachusetts Institute Of Technology |
Methods and products related to pulmonary delivery of polysaccharides
|
HU230385B1
(hu)
*
|
2001-09-12 |
2016-03-29 |
SIGMA-TAU - Research Switzerland S.A |
Részlegesen deszulfatált glükóz-amino-glükánok származékai mint a heparanáz enzim inhibitorai, előállításuk és alkalmazásuk, valamint ilyen származékokat tartalmazó gyógyszerkészítmények
|
US7285536B2
(en)
|
2001-12-05 |
2007-10-23 |
Yeda Research And Development Co., Ltd. |
Anti-cancer therapeutic compounds
|
EP2402753A1
(en)
|
2002-03-11 |
2012-01-04 |
Momenta Pharmaceuticals, Inc. |
Analysis of sulfated polysaccharides
|
EP1551852A4
(en)
*
|
2002-04-25 |
2007-03-21 |
Momenta Pharmaceuticals Inc |
METHOD AND PRODUCTS FOR MUCOSAL DELIVERY
|
ITMI20031679A1
(it)
*
|
2003-08-29 |
2005-02-28 |
Opocrin Spa |
Processo per la produzione di eparine a basso peso
|
EP1582531A1
(en)
|
2004-03-24 |
2005-10-05 |
Aventis Pharma S.A. |
Process for oxidizing unfractionated heparins and detecting presence or absence of glycoserine in heparin and heparin products
|
WO2007019554A2
(en)
*
|
2005-08-08 |
2007-02-15 |
Momenta Pharmaceuticals, Inc. |
Polysaccharides for delivery of active agents
|
ATE552004T1
(de)
|
2005-11-30 |
2012-04-15 |
Istituto G Ronzoni |
Oral verabreichbare heparinderivate
|
US9139876B1
(en)
|
2007-05-03 |
2015-09-22 |
Momenta Pharmacueticals, Inc. |
Method of analyzing a preparation of a low molecular weight heparin
|
WO2009007224A1
(en)
*
|
2007-07-10 |
2009-01-15 |
Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. |
Low molecular weight heparin derivatives having neuroprotective activity
|
US8592393B2
(en)
*
|
2007-11-02 |
2013-11-26 |
Momenta Pharmaceuticals, Inc. |
Polysaccharide compositions and methods of use for the treatment and prevention of disorders associated with progenitor cell mobilization
|
US8569262B2
(en)
|
2007-11-02 |
2013-10-29 |
Momenta Pharmaceuticals, Inc. |
Polysaccharide compositions and methods of use for the treatment and prevention of disorders associated with progenitor cell mobilization
|
EP2205642B1
(en)
*
|
2007-11-02 |
2016-01-27 |
Momenta Pharmaceuticals, Inc. |
Non-anticoagulant polysaccharide compositions
|
US20110112050A1
(en)
*
|
2008-05-20 |
2011-05-12 |
Crystal Clear Partnership |
Separation of polysaccharides by charge density gradient
|
MY153697A
(en)
|
2008-05-30 |
2015-03-13 |
Momenta Pharmaceuticals Inc |
Saccharide structures and methods of making and using such structures
|
US8435795B2
(en)
*
|
2010-01-19 |
2013-05-07 |
Momenta Pharmaceuticals, Inc. |
Evaluating heparin preparations
|
BR112012026542A2
(pt)
|
2010-04-16 |
2016-07-12 |
Momenta Pharmaceuticals Inc |
abordagem seletiva de tecido
|
BR112012031906A2
(pt)
|
2010-06-17 |
2016-08-23 |
Momenta Pharmaceuticals Inc |
métodos e composições para modular o crescimento de cabelo e pelos.
|
US9068957B2
(en)
|
2011-02-21 |
2015-06-30 |
Momenta Pharmaceuticals, Inc. |
Evaluating heparin preparations
|
CN104144950B
(zh)
*
|
2011-12-19 |
2017-09-05 |
迪乐方有限责任公司 |
含有重复的二糖单元的非抗凝的葡糖胺聚糖及其医药用途
|
WO2013095215A1
(en)
|
2011-12-19 |
2013-06-27 |
Dilaforette Ab |
Low anticoagulant heparins
|
RU2014143017A
(ru)
*
|
2012-03-26 |
2016-05-20 |
Дилафор Аб |
Препараты для индукции родов
|
US10016449B2
(en)
|
2013-05-28 |
2018-07-10 |
Momenta Pharmaceuticals, Inc. |
Pharmaceutical compositions
|
GB2515315A
(en)
*
|
2013-06-19 |
2014-12-24 |
Dilafor Ab |
New Processes
|
CN108424474B
(zh)
*
|
2017-02-15 |
2023-07-25 |
清华大学 |
去抗凝肝素衍生物及其用于炎症性肠病的治疗
|
EP3997238A1
(en)
|
2019-07-09 |
2022-05-18 |
Optimvia, LLC |
Methods for synthesizing anticoagulant polysaccharides
|
EP4182452A1
(en)
|
2020-07-14 |
2023-05-24 |
Optimvia, LLC |
Methods for synthesizing non-anticoagulant heparan sulfate
|