NO873231L - Diselenobis-benzosyreamider av primaere heterocykliske aminer, samt fremgangsmaate for fremstilling av forbindelsene. - Google Patents

Diselenobis-benzosyreamider av primaere heterocykliske aminer, samt fremgangsmaate for fremstilling av forbindelsene.

Info

Publication number
NO873231L
NO873231L NO873231A NO873231A NO873231L NO 873231 L NO873231 L NO 873231L NO 873231 A NO873231 A NO 873231A NO 873231 A NO873231 A NO 873231A NO 873231 L NO873231 L NO 873231L
Authority
NO
Norway
Prior art keywords
compounds
diselenobis
heterocyclic amines
nitro
alkoxy
Prior art date
Application number
NO873231A
Other languages
English (en)
Other versions
NO171215B (no
NO171215C (no
NO873231D0 (no
Inventor
Andre Welter
Axel Roemer
Sigurd Leyck
Michael John Parnham
Original Assignee
Nattermann A & Cie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nattermann A & Cie filed Critical Nattermann A & Cie
Publication of NO873231D0 publication Critical patent/NO873231D0/no
Publication of NO873231L publication Critical patent/NO873231L/no
Publication of NO171215B publication Critical patent/NO171215B/no
Publication of NO171215C publication Critical patent/NO171215C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36Radicals substituted by singly-bound nitrogen atoms
    • C07D213/40Acylated substituent nitrogen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/75Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D261/00Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D261/14Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38Nitrogen atoms
    • C07D277/44Acylated amino or imino radicals
    • C07D277/46Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30Hetero atoms other than halogen
    • C07D333/36Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Toxicology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
  • Furan Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
NO873231A 1986-08-06 1987-08-03 Analogifremgangsmaate for fremstilling av terapeutisk virksomme diselenobis-benzosyreamider NO171215C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19863626554 DE3626554A1 (de) 1986-08-06 1986-08-06 Diselenobis-benzoesaeureamide primaerer heterocyclischer amine, verfahren zur ihrer herstellung und diese enthaltende pharmazeutische praeparate

Publications (4)

Publication Number Publication Date
NO873231D0 NO873231D0 (no) 1987-08-03
NO873231L true NO873231L (no) 1988-02-08
NO171215B NO171215B (no) 1992-11-02
NO171215C NO171215C (no) 1993-02-10

Family

ID=6306768

Family Applications (1)

Application Number Title Priority Date Filing Date
NO873231A NO171215C (no) 1986-08-06 1987-08-03 Analogifremgangsmaate for fremstilling av terapeutisk virksomme diselenobis-benzosyreamider

Country Status (19)

Country Link
US (1) US4910313A (no)
EP (1) EP0257306B1 (no)
JP (1) JPH0830060B2 (no)
KR (1) KR960001202B1 (no)
AT (1) ATE56436T1 (no)
AU (1) AU598285B2 (no)
CA (1) CA1303038C (no)
DD (1) DD261597A5 (no)
DE (2) DE3626554A1 (no)
DK (1) DK169407B1 (no)
ES (1) ES2017483B3 (no)
FI (1) FI85018C (no)
GR (1) GR3001180T3 (no)
HU (1) HU197753B (no)
IE (1) IE60366B1 (no)
NO (1) NO171215C (no)
PT (1) PT85501B (no)
SU (1) SU1597097A3 (no)
ZA (1) ZA875821B (no)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5128365A (en) * 1989-07-19 1992-07-07 The Trustees Of Columbia University In The City Of New York Compounds having glutathione peroxidase activity and use thereof
DE3937170A1 (de) * 1989-11-08 1991-05-16 Nattermann A & Cie Benzylselenobenzamide von aminopyridinen und picolylaminen
DE3937171A1 (de) * 1989-11-08 1991-05-16 Nattermann A & Cie Picolylselenobenzamide von aminopyridinen, anilinen und picolylaminen
KR100214453B1 (ko) * 1992-01-17 1999-08-02 스즈키 다다시 경피적 관상동맥 형성술 후의 재협착 억제제
FR2757857B1 (fr) * 1996-12-27 1999-04-23 Oxis International Sa Diselenures et selenosulfures aromatiques, leur preparation et leurs utilisations, notamment therapeutiques
EP1174423A4 (en) 1999-03-31 2008-03-19 Arne Holmgren SUBSTRATES FOR THIOREDOXINE REDUCTASE
US7776925B2 (en) * 2002-03-06 2010-08-17 Duke University Reversing, postponing or preventing the occurrence of GTN tolerance and/or generation of reactive oxygen species from mitochondria
US10058542B1 (en) 2014-09-12 2018-08-28 Thioredoxin Systems Ab Composition comprising selenazol or thiazolone derivatives and silver and method of treatment therewith

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3027075A1 (de) * 1980-07-17 1982-02-18 A. Nattermann & Cie GmbH, 5000 Köln Benzisoselenazolone, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
DE3027073C2 (de) * 1980-07-17 1985-03-07 A. Nattermann & Cie GmbH, 5000 Köln Pharmazeutische Präparate, enthaltend 2-Phenyl-1,2-benzisoselenazol-3(2H)-on
DE3027074A1 (de) * 1980-07-17 1982-02-18 A. Nattermann & Cie GmbH, 5000 Köln Benzisoselenazolon enthaltende pharmazeutische praeparate und ihre verwendung
DE3226284A1 (de) * 1982-07-14 1984-01-19 A. Nattermann & Cie GmbH, 5000 Köln Neue benzisoselenazolone, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
EP0165534B1 (de) * 1984-06-22 1989-03-15 A. Nattermann & Cie. GmbH S-(Carbamoyl-phenylselenyl)-Derivate des Glutathions und von Aminomercaptocarbonsäuren, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Präparate
DE3443467A1 (de) * 1984-11-29 1986-05-28 A. Nattermann & Cie GmbH, 5000 Köln Mercaptanderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
EP0198277B1 (de) * 1985-04-12 1989-05-03 A. Nattermann & Cie. GmbH Diselenobis-benzoesäureamide primärer und sekundärer Amine, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Präparate
DE3515272C2 (de) * 1985-04-27 1993-10-14 Nattermann A & Cie Benzisoselenazolone, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Präparate

Also Published As

Publication number Publication date
JPH0830060B2 (ja) 1996-03-27
DD261597A5 (de) 1988-11-02
ATE56436T1 (de) 1990-09-15
US4910313A (en) 1990-03-20
PT85501B (pt) 1990-06-29
IE60366B1 (en) 1994-07-13
GR3001180T3 (en) 1992-06-30
DK409087D0 (da) 1987-08-05
KR960001202B1 (ko) 1996-01-24
KR880002889A (ko) 1988-05-12
ZA875821B (en) 1988-02-10
HU197753B (en) 1989-05-29
ES2017483B3 (es) 1991-02-16
AU598285B2 (en) 1990-06-21
EP0257306B1 (en) 1990-09-12
AU7665187A (en) 1988-02-11
IE872033L (en) 1988-02-06
JPS6379875A (ja) 1988-04-09
DK169407B1 (da) 1994-10-24
FI85018B (fi) 1991-11-15
FI85018C (fi) 1992-02-25
NO171215B (no) 1992-11-02
PT85501A (en) 1987-09-01
SU1597097A3 (ru) 1990-09-30
FI873383A (fi) 1988-02-07
DE3764910D1 (de) 1990-10-18
FI873383A0 (fi) 1987-08-04
EP0257306A1 (en) 1988-03-02
NO171215C (no) 1993-02-10
CA1303038C (en) 1992-06-09
NO873231D0 (no) 1987-08-03
HUT44572A (en) 1988-03-28
DE3626554A1 (de) 1988-02-18
DK409087A (da) 1988-02-07

Similar Documents

Publication Publication Date Title
FI892787A (fi) Analogiamenetelmä terapeuttisesti käyttökelpoisten 1-indolyylialkyyli-4-(substituoitu pyridinyyli)piperatsiinien valmistamiseksi
ATE136882T1 (de) Carbamidsäureester-derivate, mittel und herstellungsverfahren
IT1229570B (it) Derivati fluorurati di acidi biliari, loro preparazione e composizioni farmaceutiche che li contengono.
ES2164164T3 (es) Derivados de aminotetrazol utiles como inhibidores de oxido nitrico sintasa.
SE8504014L (sv) Etylendiaminmonoamid-derivat
IT1229569B (it) Derivati di acidi biliari, loro preparazione e composizioni farmaceutiche che li contengono.
NO873231L (no) Diselenobis-benzosyreamider av primaere heterocykliske aminer, samt fremgangsmaate for fremstilling av forbindelsene.
DK163144C (da) Diethylaminoalkoxybenzhydrolderivater og farmaceutisk acceptable syreadditionssalte og kvaternaere ammoniumsalte deraf, fremgangsmaade til fremstilling heraf, farmaceutisk praeparat og fremgangsmaade til fremstilling heraf
ES2129073T3 (es) Derivados del acido 4-fenilcarbamoil-3-isoxazol-carboxilico con actividad antiinflamatoria.
ATE48276T1 (de) 1,6-naphthyridin-derivate, verfahren zu deren herstellung und diese enthaltende arzneimittel.
FR2449677B1 (fr) Nouveaux derives de benzoyl-2 glycylanilides substitues, leur preparation et leur application en tant que medicaments anxiolytiques
NO159927C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive aromatiske aminoacetylener.
ATE52776T1 (de) 1-phenyl-3-benzazepine.
LV5491A3 (lv) 2-tiazolidinona atvasinajumu iegusanas panemiens
DE3781783D1 (de) N-alkyl-derivate von 2-amino-6,7-dimethoxytetralin, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen mit antihypertensiver wirkung.
ES557208A0 (es) Un procedimiento para preparar derivados de dihidropirrol (112-b)-isoquinoleina
SE7910430L (sv) Cyklododekanderivat jemte sett for deras framstellning
ATE95697T1 (de) Uricosuretische zusammensetzung.
DK428686D0 (da) Naphthalenderivater
ES2056211T3 (es) Derivados de acilsulfonamida de acidos alfa-carbocicliltoluicos usados como antagonistas de leucotrienos.
IT1210914B (it) Eterociclilfenilsolfonil e fosfonilamidine sostituite, procedimento per la loro preparazione e loro uso farmaceutico.
EA200100163A1 (ru) Новые производные 6-деоксиэритромицина, способ их получения и их применение в качестве лекарственных средств