DK409087D0 - Diselenobis benzoesyreamider af primaere heterocykliske aminer, fremgangsmaade til deres fremstilling samt farmaceutiske forbindelser indeholdende disse - Google Patents

Diselenobis benzoesyreamider af primaere heterocykliske aminer, fremgangsmaade til deres fremstilling samt farmaceutiske forbindelser indeholdende disse

Info

Publication number
DK409087D0
DK409087D0 DK409087A DK409087A DK409087D0 DK 409087 D0 DK409087 D0 DK 409087D0 DK 409087 A DK409087 A DK 409087A DK 409087 A DK409087 A DK 409087A DK 409087 D0 DK409087 D0 DK 409087D0
Authority
DK
Denmark
Prior art keywords
benzoic acid
acid amides
heterocyclic amines
nitro
alkoxy
Prior art date
Application number
DK409087A
Other languages
English (en)
Other versions
DK409087A (da
DK169407B1 (da
Inventor
Andre Welter
Axel Roemer
Sigurd Leyck
Michael John Parnham
Original Assignee
Nattermann A & Cie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nattermann A & Cie filed Critical Nattermann A & Cie
Publication of DK409087D0 publication Critical patent/DK409087D0/da
Publication of DK409087A publication Critical patent/DK409087A/da
Application granted granted Critical
Publication of DK169407B1 publication Critical patent/DK169407B1/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36Radicals substituted by singly-bound nitrogen atoms
    • C07D213/40Acylated substituent nitrogen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/75Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D261/00Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D261/14Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38Nitrogen atoms
    • C07D277/44Acylated amino or imino radicals
    • C07D277/46Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30Hetero atoms other than halogen
    • C07D333/36Nitrogen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Toxicology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Furan Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK409087A 1986-08-06 1987-08-05 Diselenobisbenzoesyreamider af primære heterocykliske aminer, fremgangsmåde til deres fremstilling samt farmaceutiske præparater indeholdende disse DK169407B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3626554 1986-08-06
DE19863626554 DE3626554A1 (de) 1986-08-06 1986-08-06 Diselenobis-benzoesaeureamide primaerer heterocyclischer amine, verfahren zur ihrer herstellung und diese enthaltende pharmazeutische praeparate

Publications (3)

Publication Number Publication Date
DK409087D0 true DK409087D0 (da) 1987-08-05
DK409087A DK409087A (da) 1988-02-07
DK169407B1 DK169407B1 (da) 1994-10-24

Family

ID=6306768

Family Applications (1)

Application Number Title Priority Date Filing Date
DK409087A DK169407B1 (da) 1986-08-06 1987-08-05 Diselenobisbenzoesyreamider af primære heterocykliske aminer, fremgangsmåde til deres fremstilling samt farmaceutiske præparater indeholdende disse

Country Status (19)

Country Link
US (1) US4910313A (da)
EP (1) EP0257306B1 (da)
JP (1) JPH0830060B2 (da)
KR (1) KR960001202B1 (da)
AT (1) ATE56436T1 (da)
AU (1) AU598285B2 (da)
CA (1) CA1303038C (da)
DD (1) DD261597A5 (da)
DE (2) DE3626554A1 (da)
DK (1) DK169407B1 (da)
ES (1) ES2017483B3 (da)
FI (1) FI85018C (da)
GR (1) GR3001180T3 (da)
HU (1) HU197753B (da)
IE (1) IE60366B1 (da)
NO (1) NO171215C (da)
PT (1) PT85501B (da)
SU (1) SU1597097A3 (da)
ZA (1) ZA875821B (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5128365A (en) * 1989-07-19 1992-07-07 The Trustees Of Columbia University In The City Of New York Compounds having glutathione peroxidase activity and use thereof
DE3937170A1 (de) * 1989-11-08 1991-05-16 Nattermann A & Cie Benzylselenobenzamide von aminopyridinen und picolylaminen
DE3937171A1 (de) * 1989-11-08 1991-05-16 Nattermann A & Cie Picolylselenobenzamide von aminopyridinen, anilinen und picolylaminen
CA2126465C (en) * 1992-01-17 2002-03-05 Kazuhisa Kodama Inhibitor for restenosis after percutaneous coronary arterioplasty
FR2757857B1 (fr) * 1996-12-27 1999-04-23 Oxis International Sa Diselenures et selenosulfures aromatiques, leur preparation et leurs utilisations, notamment therapeutiques
EP1174423A4 (en) 1999-03-31 2008-03-19 Arne Holmgren SUBSTRATES FOR THIOREDOXINE REDUCTASE
US7776925B2 (en) * 2002-03-06 2010-08-17 Duke University Reversing, postponing or preventing the occurrence of GTN tolerance and/or generation of reactive oxygen species from mitochondria
US10058542B1 (en) 2014-09-12 2018-08-28 Thioredoxin Systems Ab Composition comprising selenazol or thiazolone derivatives and silver and method of treatment therewith

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3027074A1 (de) * 1980-07-17 1982-02-18 A. Nattermann & Cie GmbH, 5000 Köln Benzisoselenazolon enthaltende pharmazeutische praeparate und ihre verwendung
DE3027073C2 (de) * 1980-07-17 1985-03-07 A. Nattermann & Cie GmbH, 5000 Köln Pharmazeutische Präparate, enthaltend 2-Phenyl-1,2-benzisoselenazol-3(2H)-on
DE3027075A1 (de) * 1980-07-17 1982-02-18 A. Nattermann & Cie GmbH, 5000 Köln Benzisoselenazolone, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
DE3226284A1 (de) * 1982-07-14 1984-01-19 A. Nattermann & Cie GmbH, 5000 Köln Neue benzisoselenazolone, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
DE3568775D1 (en) * 1984-06-22 1989-04-20 Nattermann A & Cie S-(carbamoyl-phenylselenyl) derivatives of glutathion and of amino mercaptocarboxylic acids, process for their preparation and pharmaceutical preparations containing them
DE3443467A1 (de) * 1984-11-29 1986-05-28 A. Nattermann & Cie GmbH, 5000 Köln Mercaptanderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
DE3663139D1 (en) * 1985-04-12 1989-06-08 Nattermann A & Cie Diseleno-bis-benzamides of primary and secondary amines, processes for their production and pharmaceutical preparations containing them
DE3515272C2 (de) * 1985-04-27 1993-10-14 Nattermann A & Cie Benzisoselenazolone, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Präparate

Also Published As

Publication number Publication date
SU1597097A3 (ru) 1990-09-30
DD261597A5 (de) 1988-11-02
US4910313A (en) 1990-03-20
DE3626554A1 (de) 1988-02-18
AU7665187A (en) 1988-02-11
FI873383A0 (fi) 1987-08-04
PT85501B (pt) 1990-06-29
IE60366B1 (en) 1994-07-13
GR3001180T3 (en) 1992-06-30
HU197753B (en) 1989-05-29
DK409087A (da) 1988-02-07
NO873231D0 (no) 1987-08-03
NO873231L (no) 1988-02-08
HUT44572A (en) 1988-03-28
CA1303038C (en) 1992-06-09
EP0257306A1 (en) 1988-03-02
NO171215B (no) 1992-11-02
JPH0830060B2 (ja) 1996-03-27
ES2017483B3 (es) 1991-02-16
ZA875821B (en) 1988-02-10
EP0257306B1 (en) 1990-09-12
FI873383A (fi) 1988-02-07
FI85018B (fi) 1991-11-15
ATE56436T1 (de) 1990-09-15
DE3764910D1 (de) 1990-10-18
AU598285B2 (en) 1990-06-21
PT85501A (en) 1987-09-01
NO171215C (no) 1993-02-10
JPS6379875A (ja) 1988-04-09
KR960001202B1 (ko) 1996-01-24
KR880002889A (ko) 1988-05-12
IE872033L (en) 1988-02-06
FI85018C (fi) 1992-02-25
DK169407B1 (da) 1994-10-24

Similar Documents

Publication Publication Date Title
FI892787A (fi) Analogiamenetelmä terapeuttisesti käyttökelpoisten 1-indolyylialkyyli-4-(substituoitu pyridinyyli)piperatsiinien valmistamiseksi
ATE136882T1 (de) Carbamidsäureester-derivate, mittel und herstellungsverfahren
ES2164164T3 (es) Derivados de aminotetrazol utiles como inhibidores de oxido nitrico sintasa.
EA200100755A1 (ru) 4-оксо-1,4-дигидро-3-хинолинкарбоксамиды как антивирусные агенты
SE8504014L (sv) Etylendiaminmonoamid-derivat
DK409087A (da) Diselenobis benzoesyreamider af primaere heterocykliske aminer, fremgangsmaade til deres fremstilling samt farmaceutiske forbindelser indeholdende disse
ES543788A0 (es) Procedimiento de preparacion de nuevos derivados a-etilben- zol con un grupo piridinometoxi sustituido y de sus sales deadicion acidas y cuaternarias
DK165247C (da) 2,3,4,5-substituerede 1,6-naphthyridinderivater, deres fremstilling samt anvendelse af disse til fremstilling af laegemidler til bekaempelse af cardiale, cerebrale og perifere karlidelser, myocardial iskaemi, cerebral infarkt, lungethrombose, stenoser, arterioscleroser og hjerte-kredsloebslidelser og laegemiddel indeholdende disse derivater
ATE205209T1 (de) Chinolincarbonsäurederivate und ihre salze
DE3781783T2 (de) N-alkyl-derivate von 2-amino-6,7-dimethoxytetralin, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen mit antihypertensiver wirkung.
FI861001A (fi) Benzo/c/-1,5-naftyridiner, foerfarande foer deras framstaellning och i deras framstaellning anvaendbara mellanprodukter samt deras anvaendning saosom laekemedel.
DK553482A (da) Fremgangsmaade til fremstilling af n,n-disubstituerede alkenamider og phenylalkenamider
SE7910430L (sv) Cyklododekanderivat jemte sett for deras framstellning
DE3685702T2 (de) Naphthalenische antipsoriasismittel und ihr herstellungsverfahren.
EA200100163A1 (ru) Новые производные 6-деоксиэритромицина, способ их получения и их применение в качестве лекарственных средств
ATE22683T1 (de) Substituiertes heterocyclylphenylsulphonyl und phosphonylamidine, verfahren zu deren herstellung und deren pharmazeutische anwendung.
TH2445A (th) ไพริมิดีนที่ถูกแทนที่

Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed