DE3781783D1 - N-alkyl-derivate von 2-amino-6,7-dimethoxytetralin, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen mit antihypertensiver wirkung. - Google Patents

N-alkyl-derivate von 2-amino-6,7-dimethoxytetralin, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen mit antihypertensiver wirkung.

Info

Publication number
DE3781783D1
DE3781783D1 DE8787830449T DE3781783T DE3781783D1 DE 3781783 D1 DE3781783 D1 DE 3781783D1 DE 8787830449 T DE8787830449 T DE 8787830449T DE 3781783 T DE3781783 T DE 3781783T DE 3781783 D1 DE3781783 D1 DE 3781783D1
Authority
DE
Germany
Prior art keywords
amino
alkyl derivatives
dimethoxytetraline
production
pharmaceutical compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8787830449T
Other languages
English (en)
Other versions
DE3781783T2 (de
Inventor
Mauro Marzi
Maria Ornella Tinti
Fabio Romano Di
Domenico Misiti
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sigma Tau Industrie Farmaceutiche Riunite SpA
Original Assignee
Sigma Tau Industrie Farmaceutiche Riunite SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Industrie Farmaceutiche Riunite SpA filed Critical Sigma Tau Industrie Farmaceutiche Riunite SpA
Publication of DE3781783D1 publication Critical patent/DE3781783D1/de
Application granted granted Critical
Publication of DE3781783T2 publication Critical patent/DE3781783T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE8787830449T 1986-12-23 1987-12-21 N-alkyl-derivate von 2-amino-6,7-dimethoxytetralin, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen mit antihypertensiver wirkung. Expired - Fee Related DE3781783T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT48779/86A IT1199339B (it) 1986-12-23 1986-12-23 N-alchil derivati della 2-ammino-6,7-dimetossi tetralina,procedimenti per la loro preparazione e composizioni farmaceutiche ad attivita'an tiipertensiva che li contengono

Publications (2)

Publication Number Publication Date
DE3781783D1 true DE3781783D1 (de) 1992-10-22
DE3781783T2 DE3781783T2 (de) 1993-02-25

Family

ID=11268513

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8787830449T Expired - Fee Related DE3781783T2 (de) 1986-12-23 1987-12-21 N-alkyl-derivate von 2-amino-6,7-dimethoxytetralin, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen mit antihypertensiver wirkung.

Country Status (8)

Country Link
US (1) US5047433A (de)
EP (1) EP0273017B1 (de)
JP (1) JP2545105B2 (de)
AT (1) ATE80608T1 (de)
DE (1) DE3781783T2 (de)
ES (1) ES2035105T3 (de)
GR (1) GR3006342T3 (de)
IT (1) IT1199339B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1230931B (it) * 1989-06-27 1991-11-08 Chiesi Farma Spa Derivati di 2 ammino 1,2,3,4 tetraidronaftalene ad attivita' cardiovascolare, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono
IT1241988B (it) * 1990-06-15 1994-02-02 Sigma Tau Ind Farmaceuti 2- amminotetraline-6, 7-sostituite attive come immunomodulanti e composizioni farmaceutiche che le contengono
IL104567A (en) * 1992-02-03 1997-03-18 Fujisawa Pharmaceutical Co Ethanolamine derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same
IT1278045B1 (it) * 1995-03-09 1997-11-17 Sigma Tau Ind Farmaceuti Uso di 2-amminotetraline-6,7-sostituite per la preparazione di composizioni farmaceutiche atte al trattamento dello shock, e di

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3709996A (en) * 1963-08-02 1973-01-09 Aspro Nicholas Ltd Pharmaceutical compositions containing n-cyclopropyl-1-aminoindane compounds and adapted for administration to obtain inhibition of monoamine oxidase enzyme and process
GB1187017A (en) * 1966-07-16 1970-04-08 Aspro Nicholas Ltd Substituted 1-Amino Indanes and Tetrahydronaphthalens
US3629463A (en) * 1969-04-15 1971-12-21 Aspro Nicholas Ltd Pharmaceutical compositions containing n-cyclopropyl-1-amino-1 2 3 4-tetrahydronaphthalenes and use of such n-cyclopropyl compounds as hypotensives
US3930022A (en) * 1972-07-03 1975-12-30 Squibb & Sons Inc Certain tetrahydronaphthalenes used in the treatment of cardiac arrhythmia
US4181738A (en) * 1976-11-30 1980-01-01 Cornell Research Foundation, Inc. Catecholamine derivatives, a process for their preparation and pharmaceutical compositions thereof
US4314082A (en) * 1978-07-14 1982-02-02 American Hospital Supply Corporation Derivatives of 2-amino-6,7-dihydroxytetrahydro naphthalene (ADTN)
EP0033789B1 (de) * 1980-01-30 1984-03-07 American Hospital Supply Corporation 2-alpha-Methyl-dopaminimino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalin, seine Salze, und Verfahren zu dessen Herstellung
EP0168505B1 (de) * 1984-05-22 1989-08-09 Whitby Research Incorporated Substituierte 2-Aminotetraline und Verfahren zur Herstellung
IL79323A (en) * 1985-07-10 1990-03-19 Sanofi Sa Phenylethanolaminotetralines,their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
ES2035105T3 (es) 1993-04-16
IT1199339B (it) 1988-12-30
JPS63190858A (ja) 1988-08-08
US5047433A (en) 1991-09-10
GR3006342T3 (de) 1993-06-21
DE3781783T2 (de) 1993-02-25
EP0273017A2 (de) 1988-06-29
ATE80608T1 (de) 1992-10-15
EP0273017B1 (de) 1992-09-16
EP0273017A3 (en) 1989-03-01
JP2545105B2 (ja) 1996-10-16
IT8648779A0 (it) 1986-12-23

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Legal Events

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8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee