DE3675778D1 - (2-amino-4-aryl-thiazol-5-yl)aethanol, und deren derivate mit diuretischer aktivitaet und verfahren zu deren herstellung. - Google Patents
(2-amino-4-aryl-thiazol-5-yl)aethanol, und deren derivate mit diuretischer aktivitaet und verfahren zu deren herstellung.Info
- Publication number
- DE3675778D1 DE3675778D1 DE8686116033T DE3675778T DE3675778D1 DE 3675778 D1 DE3675778 D1 DE 3675778D1 DE 8686116033 T DE8686116033 T DE 8686116033T DE 3675778 T DE3675778 T DE 3675778T DE 3675778 D1 DE3675778 D1 DE 3675778D1
- Authority
- DE
- Germany
- Prior art keywords
- derivatives
- aethanol
- thiazol
- aryl
- amino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/42—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/40—Unsubstituted amino or imino radicals
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP86116033A EP0267986B1 (de) | 1986-11-20 | 1986-11-20 | (2-Amino-4-aryl-thiazol-5-yl)Äthanol, und deren Derivate mit diuretischer Aktivität und Verfahren zu deren Herstellung |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3675778D1 true DE3675778D1 (de) | 1991-01-03 |
Family
ID=8195612
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8686116033T Expired - Fee Related DE3675778D1 (de) | 1986-11-20 | 1986-11-20 | (2-amino-4-aryl-thiazol-5-yl)aethanol, und deren derivate mit diuretischer aktivitaet und verfahren zu deren herstellung. |
Country Status (5)
Country | Link |
---|---|
US (1) | US4761422A (de) |
EP (1) | EP0267986B1 (de) |
JP (1) | JPS63135376A (de) |
AT (1) | ATE58532T1 (de) |
DE (1) | DE3675778D1 (de) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2110175A1 (en) * | 1991-05-30 | 1992-12-10 | Atsuro Nakazato | Aminoalkylthiazole derivative |
US5528235A (en) * | 1991-09-03 | 1996-06-18 | Edward D. Lin | Multi-status multi-function data processing key and key array |
JP5341516B2 (ja) * | 2005-09-13 | 2013-11-13 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | 2−アニリン−4−アリール置換チアゾール誘導体 |
CN101096363B (zh) | 2006-06-27 | 2011-05-11 | 中国人民解放军军事医学科学院毒物药物研究所 | 2,4,5-三取代噻唑类化合物、其制备方法、药物组合物及其制药用途 |
US8440701B2 (en) | 2007-10-18 | 2013-05-14 | Janssen Pharmaceutica Nv | Trisubstituted 1,2,4 triazoles |
JO2784B1 (en) | 2007-10-18 | 2014-03-15 | شركة جانسين فارماسوتيكا ان. في | 5,3,1 - Triazole substitute derivative |
NZ587669A (en) | 2008-03-19 | 2011-07-29 | Janssen Pharmaceutica Nv | Trisubstituted 1, 2, 4 -triazoles as nicotinic acetylcholine receptor modulators |
BRPI0912196A2 (pt) | 2008-05-09 | 2015-10-06 | Janssen Pharmaceutica Nv | pirazóis trissubstituídos como moduladores do receptor de acetilcolina. |
US9453002B2 (en) | 2013-08-16 | 2016-09-27 | Janssen Pharmaceutica Nv | Substituted imidazoles as N-type calcium channel blockers |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3806515A (en) * | 1968-07-31 | 1974-04-23 | W Houlihan | Certain 2-alkyl-3-phenyl-5,6-dihydroimidazo(2,1-b)thiazoles |
BE795907A (fr) * | 1972-02-25 | 1973-06-18 | Luso Farmaco Inst | 2-amino-4-arylthiazoles 5-substitues et leur preparation |
DE3049460A1 (de) * | 1980-12-30 | 1982-07-29 | Hoechst Ag, 6000 Frankfurt | "thiazolinderivate, verfahren zu ihrer herstellung, ihre verwendung sowie pharmazeutische praeparate auf basis dieser verbindungen |
-
1986
- 1986-11-19 US US06/932,929 patent/US4761422A/en not_active Expired - Fee Related
- 1986-11-20 AT AT86116033T patent/ATE58532T1/de not_active IP Right Cessation
- 1986-11-20 EP EP86116033A patent/EP0267986B1/de not_active Expired - Lifetime
- 1986-11-20 DE DE8686116033T patent/DE3675778D1/de not_active Expired - Fee Related
- 1986-11-21 JP JP61277902A patent/JPS63135376A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
EP0267986B1 (de) | 1990-11-22 |
ATE58532T1 (de) | 1990-12-15 |
EP0267986A1 (de) | 1988-05-25 |
JPS63135376A (ja) | 1988-06-07 |
US4761422A (en) | 1988-08-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |