DE3882895D1 - Imid-derivate, ihre herstellung und verwendung. - Google Patents

Imid-derivate, ihre herstellung und verwendung.

Info

Publication number
DE3882895D1
DE3882895D1 DE8888117836T DE3882895T DE3882895D1 DE 3882895 D1 DE3882895 D1 DE 3882895D1 DE 8888117836 T DE8888117836 T DE 8888117836T DE 3882895 T DE3882895 T DE 3882895T DE 3882895 D1 DE3882895 D1 DE 3882895D1
Authority
DE
Germany
Prior art keywords
production
imid
derivatives
imid derivatives
chem
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8888117836T
Other languages
English (en)
Other versions
DE3882895T2 (de
Inventor
Fujio Antoku
Mayumi Yoshigi
Ikutaro Saji
Kikuo Ishizumi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Pharmaceuticals Co Ltd
Original Assignee
Sumitomo Pharmaceuticals Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Pharmaceuticals Co Ltd filed Critical Sumitomo Pharmaceuticals Co Ltd
Publication of DE3882895D1 publication Critical patent/DE3882895D1/de
Application granted granted Critical
Publication of DE3882895T2 publication Critical patent/DE3882895T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Indole Compounds (AREA)
DE88117836T 1987-10-26 1988-10-26 Imid-Derivate, ihre Herstellung und Verwendung. Expired - Fee Related DE3882895T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP27146287 1987-10-26

Publications (2)

Publication Number Publication Date
DE3882895D1 true DE3882895D1 (de) 1993-09-09
DE3882895T2 DE3882895T2 (de) 1993-11-18

Family

ID=17500372

Family Applications (1)

Application Number Title Priority Date Filing Date
DE88117836T Expired - Fee Related DE3882895T2 (de) 1987-10-26 1988-10-26 Imid-Derivate, ihre Herstellung und Verwendung.

Country Status (6)

Country Link
US (1) US4937249A (de)
EP (1) EP0314098B1 (de)
AT (1) ATE92489T1 (de)
CA (1) CA1335289C (de)
DE (1) DE3882895T2 (de)
ES (1) ES2059468T3 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5364866A (en) * 1989-05-19 1994-11-15 Hoechst-Roussel Pharmaceuticals, Inc. Heteroarylpiperidines, pyrrolidines and piperazines and their use as antipsychotics and analetics
US5776963A (en) * 1989-05-19 1998-07-07 Hoechst Marion Roussel, Inc. 3-(heteroaryl)-1- (2,3-dihydro-1h-isoindol-2-yl)alkyl!pyrrolidines and 3-(heteroaryl)-1- (2,3-dihydro-1h-indol-1-yl)alkyl!pyrrolidines and related compounds and their therapeutic untility
US5561128A (en) * 1989-05-19 1996-10-01 Hoechst-Roussel Pharmaceuticals, Inc. N-[(4-(heteroaryl)-1-piperidinyl)alkyl]-10,11-dihydro-5H-dibenz[B,F]azepines and related compounds and their therapeutic utility
US5703088A (en) * 1989-08-21 1997-12-30 Beth Israel Deaconess Medical Center, Inc. Topical application of spiperone or derivatives thereof for treatment of pathological conditions associated with immune responses
FR2671350A1 (fr) * 1991-01-08 1992-07-10 Adir Nouveaux derives de benzisoxazole et de benzisothiazole, leur procede de preparation, et les compositions pharmaceutiques les renfermant.
US5574041A (en) * 1990-03-16 1996-11-12 Beth Israel Hospital Association Use of spiperone derivatives as immunosuppressant agents
JP2800953B2 (ja) * 1990-07-06 1998-09-21 住友製薬株式会社 新規なイミド誘導体
US5055476A (en) * 1990-08-13 1991-10-08 Hoechst-Roussel Pharmaceuticals Incorporated 3-(1,2-benzisoxazol-3-yl)-4-pyridinamines and derivatives
US5532240A (en) * 1991-12-26 1996-07-02 Yoshitomi Pharmaceutical Industries, Ltd. Condensed thiophene compound and pharmaceutical use thereof
GB9202915D0 (en) * 1992-02-12 1992-03-25 Wellcome Found Chemical compounds
US5693645A (en) * 1992-12-23 1997-12-02 Beth Israel Deaconess Medical Center, Inc. Use of spiperone or spiperone derivatives as immunosuppressant agents
FR2749304B1 (fr) * 1996-06-04 1998-06-26 Adir Nouveaux derives du 3-(piperid-4-yl)1,2-benzisoxazole et du 3-(piperazin-4-yl)1,2-benzisoxazole, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
JP2004262812A (ja) * 2003-02-28 2004-09-24 Rohto Pharmaceut Co Ltd 眼圧低下剤
CN102952064A (zh) * 2011-08-19 2013-03-06 天津药物研究院 一种医药中间体顺式-外-二环[2.2.1]庚烷-2.3-二甲酰亚胺的制备方法
CN111909124A (zh) * 2020-08-03 2020-11-10 江西司太立制药有限公司 一种顺式-2,3-降冰片烷二羧酸酐的制备方法
CN114685349B (zh) * 2020-12-28 2023-10-24 四川科瑞德制药股份有限公司 顺-外-二环[2.2.1]庚烷-2,3-二甲酰亚胺的制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0000254B1 (de) * 1977-06-20 1981-06-10 Beecham Group Plc Antithrombotisches 2-(Gamma-(1-piperidinyl)1,2-Benzisothiazol-3-on, seine therapeutisch zulässigen Säureadditionssalze, ihre Herstellung und ihre Präparate
DE3048663A1 (de) * 1980-12-23 1982-07-22 Grünenthal GmbH, 5190 Stolberg Neue lactamverbindungen, diese enthaltende arzneimittel und verfahren zur herstellung dieser verbindungen und arzneimittel
US4355037A (en) * 1981-11-12 1982-10-19 Hoechst-Roussel Pharmaceuticals 3-(4-Piperidyl)-1,2-benzisoxales
US4408053A (en) * 1981-11-12 1983-10-04 Hoechst-Roussel Pharmaceuticals Inc. (4-Piperidyl)-substituted phenyl ketones
US4408054A (en) * 1981-11-12 1983-10-04 Hoechst-Roussel Pharmaceuticals Inc. Oximes of 4-benzoyl-piperidines
US4352811A (en) * 1981-11-12 1982-10-05 Hoechst-Roussel Pharmaceuticals Inc. 3-(1-Substituted-4-piperidyl)-1,2-benzisoxazoles
US4411901A (en) * 1981-12-23 1983-10-25 Mead Johnson & Company Benzisothiazole and benzisoxazole piperazine derivatives
US4390544A (en) * 1982-04-09 1983-06-28 Hoechst-Roussel Pharmaceuticals Inc. {1-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-4-(2-oxo-1-benzimidazolinyl}p
US4524206A (en) * 1983-09-12 1985-06-18 Mead Johnson & Company 1-Heteroaryl-4-(2,5-pyrrolidinedion-1-yl)alkyl)piperazine derivatives
US4804663A (en) * 1985-03-27 1989-02-14 Janssen Pharmaceutica N.V. 3-piperidinyl-substituted 1,2-benzisoxazoles and 1,2-benzisothiazoles
JP2660407B2 (ja) * 1986-09-26 1997-10-08 住友製薬株式会社 新規なイミド誘導体

Also Published As

Publication number Publication date
US4937249A (en) 1990-06-26
DE3882895T2 (de) 1993-11-18
ATE92489T1 (de) 1993-08-15
ES2059468T3 (es) 1994-11-16
EP0314098B1 (de) 1993-08-04
EP0314098A3 (en) 1990-01-03
CA1335289C (en) 1995-04-18
EP0314098A2 (de) 1989-05-03

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee