ES2031569T3 - Derivados de acidos quinolinocarboxilicos. - Google Patents

Derivados de acidos quinolinocarboxilicos.

Info

Publication number
ES2031569T3
ES2031569T3 ES198888117810T ES88117810T ES2031569T3 ES 2031569 T3 ES2031569 T3 ES 2031569T3 ES 198888117810 T ES198888117810 T ES 198888117810T ES 88117810 T ES88117810 T ES 88117810T ES 2031569 T3 ES2031569 T3 ES 2031569T3
Authority
ES
Spain
Prior art keywords
hydrogen
quinolinocarboxilic
derivatives
acids
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198888117810T
Other languages
English (en)
Inventor
Masahiro Kise
Masahiko Kitano
Masakuni Ozaki
Kenji Kazuno
Masahito Matsuda
Ichiro Shirahase
Jun Segawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nippon Shinyaku Co Ltd
Original Assignee
Nippon Shinyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Shinyaku Co Ltd filed Critical Nippon Shinyaku Co Ltd
Application granted granted Critical
Publication of ES2031569T3 publication Critical patent/ES2031569T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Dental Preparations (AREA)
  • Display Devices Of Pinball Game Machines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Quinoline Compounds (AREA)

Abstract

UN DERIVADO DEL ACIDO QUINOLINECARBOXILICO REPRESENTADO POR LA SIGUIENTE FORMULA GENERAL (I) Y UNA SAL FISIOLOGICAMENTE ACEPTABLE DE ELLO. EN LA CUAL R1 ES LIDIGENO, ALQUIL O SUBSTITUIDO O NO SUSTITUIDO FENIL; R2 ES NITROGENO O ALQUIL Y R3 ES HIDROGENO, ALOGENO O ALGOXI. ESTOS COMPONENTES EXIBIDOS DE ACTIVIDAD ANTIBACTERIAL SON UTILES COMO REMEDIO A VARIAS ENFERMEDADES INFECCIOSAS.
ES198888117810T 1987-11-07 1988-10-26 Derivados de acidos quinolinocarboxilicos. Expired - Lifetime ES2031569T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP28155087 1987-11-07

Publications (1)

Publication Number Publication Date
ES2031569T3 true ES2031569T3 (es) 1992-12-16

Family

ID=17640743

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198888117810T Expired - Lifetime ES2031569T3 (es) 1987-11-07 1988-10-26 Derivados de acidos quinolinocarboxilicos.

Country Status (14)

Country Link
US (1) US5086049A (es)
EP (1) EP0315828B1 (es)
JP (1) JPH0751579B2 (es)
KR (1) KR950011747B1 (es)
CN (1) CN1024194C (es)
AT (1) ATE74608T1 (es)
CA (1) CA1316925C (es)
DE (1) DE3869907D1 (es)
DK (1) DK172077B1 (es)
ES (1) ES2031569T3 (es)
FI (1) FI88618C (es)
IL (1) IL88303A (es)
NO (1) NO177934C (es)
ZA (1) ZA888186B (es)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3869906D1 (de) * 1987-11-07 1992-05-14 Nippon Shinyaku Co Ltd Chinolincarbonsaeure-derivate.
AU6641190A (en) * 1989-11-17 1991-06-13 Nippon Shinyaku Co. Ltd. Quinolinecarboxylic acid derivative
WO1992006099A1 (en) * 1990-10-03 1992-04-16 Nippon Shinyaku Co., Ltd. Quinolinecarboxylic acid derivative
NO304832B1 (no) * 1992-05-27 1999-02-22 Ube Industries Aminokinolonderivater samt middel mot HIV
CA2367373C (en) 1999-03-17 2011-09-20 Daiichi Pharmaceutical Co., Ltd. Medicinal compositions
BRPI0409930A (pt) 2003-04-30 2006-04-25 Nippon Shinyaku Co Ltd cristais de solvato derivado do ácido quinolinacarboxìlico
CN100351258C (zh) * 2003-04-30 2007-11-28 日本新药株式会社 喹啉羧酸衍生物溶剂化物的结晶
WO2005073239A1 (ja) * 2004-01-30 2005-08-11 Nippon Shinyaku Co., Ltd. キノリンカルボン酸誘導体の精製方法
CN1321997C (zh) * 2004-03-03 2007-06-20 刘玉辉 一种稳定的噻丁啶喹啉羧酸盐在制备抗感染药物中的应用
CN100360539C (zh) * 2005-09-23 2008-01-09 广州白云山制药股份有限公司广州白云山化学制药厂 普卢利沙星的制备方法
CN101003540A (zh) * 2006-01-18 2007-07-25 广州白云山制药股份有限公司广州白云山制药总厂 一种抗感染化合物和用途
WO2007082472A1 (en) * 2006-01-18 2007-07-26 Guangzhou Baiyunshan Pharmaceutical Co., Ltd. Guangzhou Baiyunshan Pharmaceutical Factory Anti-infective quinolone compound, preparation method thereof and use thereof
EP2137194A2 (en) * 2007-03-14 2009-12-30 Ranbaxy Laboratories Limited Process for the preparation of crystals of prulifloxacin
US20110034690A1 (en) * 2007-03-14 2011-02-10 Ranbaxy Laboratories Limited Process for the preparation of pure prulifloxacin
WO2009093268A1 (en) * 2008-01-23 2009-07-30 Ind-Swift Laboratories Limited Process for the preparation of highly pure prulifloxacin
CN101565428B (zh) * 2009-06-02 2011-06-29 重庆科瑞制药有限责任公司 普卢利沙星的制备方法
WO2011031745A1 (en) 2009-09-09 2011-03-17 Achaogen, Inc. Antibacterial fluoroquinolone analogs
CN102093393B (zh) * 2009-12-15 2014-03-26 南京长澳医药科技有限公司 一种制备普卢利沙星及其中间产物的方法
CN101768172B (zh) * 2010-01-13 2012-04-18 海南皇隆制药股份有限公司 用于抗感染的普卢利沙星的光学活性化合物和制备方法
CN102198135B (zh) * 2010-03-22 2013-05-08 北京联木医药技术发展有限公司 一种新型稳定的普卢利沙星盐酸盐在制备抗感染药物中的应用
IN2012MN02925A (es) * 2010-06-30 2015-05-22 Cipla Ltd
CN114751873A (zh) * 2022-04-25 2022-07-15 扬州市普林斯医药科技有限公司 一种1-(2,3-二氯苯基)哌嗪的制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57203067A (en) * 1981-06-10 1982-12-13 Kanebo Ltd Novel quinolinecarboxylic acid derivatives, their preparations, and antibacterial agent comprising them as active ingredient
JPS59227887A (ja) * 1983-06-09 1984-12-21 Nippon Shinyaku Co Ltd ナフチリジン誘導体
US4659734A (en) * 1983-08-15 1987-04-21 Nippon Shinyaku Co., Ltd. Olinecarboxylic acid derivatives
DE3504643A1 (de) * 1985-02-12 1986-08-14 Bayer Ag, 5090 Leverkusen 1-cyclopropyl-1,4-dihydro-4-oxo-7-(4-(2-oxo-1,3-dioxol-4-yl-methyl)-1-piperazinyl)-3-chinolin carbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
DE3542002A1 (de) * 1985-11-28 1987-06-04 Bayer Ag 1-cyclopropyl-6-fluor-1,4-dihydro-4-oxo-7- (1-piperazinyl)-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
JPS63107990A (ja) * 1986-05-14 1988-05-12 Nippon Shinyaku Co Ltd キノリンカルボン酸誘導体
US4882328A (en) * 1987-09-22 1989-11-21 Nippon Shinyaku Co. Ltd. Thiazetidine derivatives
DE3869906D1 (de) * 1987-11-07 1992-05-14 Nippon Shinyaku Co Ltd Chinolincarbonsaeure-derivate.

Also Published As

Publication number Publication date
DK172077B1 (da) 1997-10-13
CA1316925C (en) 1993-04-27
FI885128A (fi) 1989-05-08
US5086049A (en) 1992-02-04
NO884958D0 (no) 1988-11-07
EP0315828A1 (en) 1989-05-17
DK616388D0 (da) 1988-11-04
KR890008150A (ko) 1989-07-10
EP0315828B1 (en) 1992-04-08
JPH01294680A (ja) 1989-11-28
IL88303A (en) 1993-05-13
NO177934C (no) 1995-12-20
NO884958L (no) 1989-05-08
DK616388A (da) 1989-05-08
DE3869907D1 (de) 1992-05-14
CN1024194C (zh) 1994-04-13
ATE74608T1 (de) 1992-04-15
KR950011747B1 (en) 1995-10-09
CN1033055A (zh) 1989-05-24
FI885128A0 (fi) 1988-11-07
AU608911B2 (en) 1991-04-18
JPH0751579B2 (ja) 1995-06-05
ZA888186B (en) 1989-07-26
AU2467388A (en) 1989-05-11
NO177934B (no) 1995-09-11
FI88618B (fi) 1993-02-26
FI88618C (fi) 1993-06-10
IL88303A0 (en) 1989-06-30

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