ATE74608T1 - Chinolincarbonsaeure-derivate. - Google Patents
Chinolincarbonsaeure-derivate.Info
- Publication number
- ATE74608T1 ATE74608T1 AT88117810T AT88117810T ATE74608T1 AT E74608 T1 ATE74608 T1 AT E74608T1 AT 88117810 T AT88117810 T AT 88117810T AT 88117810 T AT88117810 T AT 88117810T AT E74608 T1 ATE74608 T1 AT E74608T1
- Authority
- AT
- Austria
- Prior art keywords
- hydrogen
- acid derivatives
- alkyl
- quinolinecarbonic
- quinolinecarbonic acid
- Prior art date
Links
- 239000002253 acid Substances 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 150000002431 hydrogen Chemical class 0.000 abstract 2
- 208000035473 Communicable disease Diseases 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- LOAUVZALPPNFOQ-UHFFFAOYSA-N quinaldic acid Chemical class C1=CC=CC2=NC(C(=O)O)=CC=C21 LOAUVZALPPNFOQ-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Quinoline Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Dental Preparations (AREA)
- Display Devices Of Pinball Game Machines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP28155087 | 1987-11-07 | ||
| EP88117810A EP0315828B1 (de) | 1987-11-07 | 1988-10-26 | Chinolincarbonsäure-Derivate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE74608T1 true ATE74608T1 (de) | 1992-04-15 |
Family
ID=17640743
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT88117810T ATE74608T1 (de) | 1987-11-07 | 1988-10-26 | Chinolincarbonsaeure-derivate. |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US5086049A (de) |
| EP (1) | EP0315828B1 (de) |
| JP (1) | JPH0751579B2 (de) |
| KR (1) | KR950011747B1 (de) |
| CN (1) | CN1024194C (de) |
| AT (1) | ATE74608T1 (de) |
| CA (1) | CA1316925C (de) |
| DE (1) | DE3869907D1 (de) |
| DK (1) | DK172077B1 (de) |
| ES (1) | ES2031569T3 (de) |
| FI (1) | FI88618C (de) |
| IL (1) | IL88303A (de) |
| NO (1) | NO177934C (de) |
| ZA (1) | ZA888186B (de) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0315827B1 (de) * | 1987-11-07 | 1992-04-08 | Nippon Shinyaku Company, Limited | Chinolincarbonsäure-Derivate |
| WO1991007412A1 (fr) * | 1989-11-17 | 1991-05-30 | Nippon Shinyaku Co., Ltd. | Derive de l'acide quinolinecarboxylique |
| WO1992006099A1 (fr) * | 1990-10-03 | 1992-04-16 | Nippon Shinyaku Co., Ltd. | Derive d'acide quinolinecarboxylique |
| NO304832B1 (no) * | 1992-05-27 | 1999-02-22 | Ube Industries | Aminokinolonderivater samt middel mot HIV |
| AU3192700A (en) | 1999-03-17 | 2000-10-04 | Daiichi Pharmaceutical Co., Ltd. | Medicinal compositions |
| KR101088988B1 (ko) | 2003-04-30 | 2011-12-01 | 니뽄 신야쿠 가부시키가이샤 | 퀴놀린카르복실산 유도체 용매화물의 결정 |
| CN100351258C (zh) * | 2003-04-30 | 2007-11-28 | 日本新药株式会社 | 喹啉羧酸衍生物溶剂化物的结晶 |
| WO2005073239A1 (ja) * | 2004-01-30 | 2005-08-11 | Nippon Shinyaku Co., Ltd. | キノリンカルボン酸誘導体の精製方法 |
| CN1321997C (zh) * | 2004-03-03 | 2007-06-20 | 刘玉辉 | 一种稳定的噻丁啶喹啉羧酸盐在制备抗感染药物中的应用 |
| CN100360539C (zh) * | 2005-09-23 | 2008-01-09 | 广州白云山制药股份有限公司广州白云山化学制药厂 | 普卢利沙星的制备方法 |
| CN101003540A (zh) * | 2006-01-18 | 2007-07-25 | 广州白云山制药股份有限公司广州白云山制药总厂 | 一种抗感染化合物和用途 |
| WO2007082472A1 (fr) * | 2006-01-18 | 2007-07-26 | Guangzhou Baiyunshan Pharmaceutical Co., Ltd. Guangzhou Baiyunshan Pharmaceutical Factory | Composé de quinolone anti-infectueux, son procédé de préparation et son utilisation |
| EP2148883A1 (de) * | 2007-03-14 | 2010-02-03 | Ranbaxy Laboratories Limited | Verfahren zur herstellung von reinem prulifloxacin |
| EP2137194A2 (de) * | 2007-03-14 | 2009-12-30 | Ranbaxy Laboratories Limited | Verfahren zur herstellung von kristallen von prulifloxacin |
| WO2009093268A1 (en) * | 2008-01-23 | 2009-07-30 | Ind-Swift Laboratories Limited | Process for the preparation of highly pure prulifloxacin |
| CN101565428B (zh) * | 2009-06-02 | 2011-06-29 | 重庆科瑞制药有限责任公司 | 普卢利沙星的制备方法 |
| WO2011031745A1 (en) | 2009-09-09 | 2011-03-17 | Achaogen, Inc. | Antibacterial fluoroquinolone analogs |
| CN102093393B (zh) * | 2009-12-15 | 2014-03-26 | 南京长澳医药科技有限公司 | 一种制备普卢利沙星及其中间产物的方法 |
| CN101768172B (zh) * | 2010-01-13 | 2012-04-18 | 海南皇隆制药股份有限公司 | 用于抗感染的普卢利沙星的光学活性化合物和制备方法 |
| CN102198135B (zh) * | 2010-03-22 | 2013-05-08 | 北京联木医药技术发展有限公司 | 一种新型稳定的普卢利沙星盐酸盐在制备抗感染药物中的应用 |
| WO2012001357A1 (en) * | 2010-06-30 | 2012-01-05 | Cipla Limited | Crystalline form of prulifloxacin and processes for its preparation |
| CN114751873B (zh) * | 2022-04-25 | 2025-02-18 | 扬州市普林斯医药科技有限公司 | 一种1-(2,3-二氯苯基)哌嗪的制备方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS57203067A (en) * | 1981-06-10 | 1982-12-13 | Kanebo Ltd | Novel quinolinecarboxylic acid derivatives, their preparations, and antibacterial agent comprising them as active ingredient |
| JPS59227887A (ja) * | 1983-06-09 | 1984-12-21 | Nippon Shinyaku Co Ltd | ナフチリジン誘導体 |
| US4659734A (en) * | 1983-08-15 | 1987-04-21 | Nippon Shinyaku Co., Ltd. | Olinecarboxylic acid derivatives |
| DE3504643A1 (de) * | 1985-02-12 | 1986-08-14 | Bayer Ag, 5090 Leverkusen | 1-cyclopropyl-1,4-dihydro-4-oxo-7-(4-(2-oxo-1,3-dioxol-4-yl-methyl)-1-piperazinyl)-3-chinolin carbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel |
| DE3542002A1 (de) * | 1985-11-28 | 1987-06-04 | Bayer Ag | 1-cyclopropyl-6-fluor-1,4-dihydro-4-oxo-7- (1-piperazinyl)-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel |
| JPS63107990A (ja) * | 1986-05-14 | 1988-05-12 | Nippon Shinyaku Co Ltd | キノリンカルボン酸誘導体 |
| EP0312794B1 (de) * | 1987-09-22 | 1993-05-19 | Nippon Shinyaku Company, Limited | Thiazetidin-Derivate |
| EP0315827B1 (de) * | 1987-11-07 | 1992-04-08 | Nippon Shinyaku Company, Limited | Chinolincarbonsäure-Derivate |
-
1988
- 1988-10-19 JP JP63263568A patent/JPH0751579B2/ja not_active Expired - Lifetime
- 1988-10-26 DE DE8888117810T patent/DE3869907D1/de not_active Expired - Fee Related
- 1988-10-26 EP EP88117810A patent/EP0315828B1/de not_active Expired - Lifetime
- 1988-10-26 ES ES198888117810T patent/ES2031569T3/es not_active Expired - Lifetime
- 1988-10-26 AT AT88117810T patent/ATE74608T1/de active
- 1988-11-01 ZA ZA888186A patent/ZA888186B/xx unknown
- 1988-11-04 DK DK616388A patent/DK172077B1/da not_active IP Right Cessation
- 1988-11-05 CN CN88107689A patent/CN1024194C/zh not_active Expired - Lifetime
- 1988-11-07 IL IL88303A patent/IL88303A/xx not_active IP Right Cessation
- 1988-11-07 NO NO884958A patent/NO177934C/no unknown
- 1988-11-07 CA CA000582460A patent/CA1316925C/en not_active Expired - Lifetime
- 1988-11-07 FI FI885128A patent/FI88618C/fi not_active IP Right Cessation
- 1988-11-07 KR KR88014591A patent/KR950011747B1/ko not_active Expired - Lifetime
-
1991
- 1991-04-08 US US07/682,434 patent/US5086049A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP0315828B1 (de) | 1992-04-08 |
| AU2467388A (en) | 1989-05-11 |
| NO884958L (no) | 1989-05-08 |
| JPH01294680A (ja) | 1989-11-28 |
| CA1316925C (en) | 1993-04-27 |
| IL88303A (en) | 1993-05-13 |
| NO177934C (no) | 1995-12-20 |
| AU608911B2 (en) | 1991-04-18 |
| JPH0751579B2 (ja) | 1995-06-05 |
| KR950011747B1 (en) | 1995-10-09 |
| FI88618B (fi) | 1993-02-26 |
| CN1024194C (zh) | 1994-04-13 |
| EP0315828A1 (de) | 1989-05-17 |
| IL88303A0 (en) | 1989-06-30 |
| NO884958D0 (no) | 1988-11-07 |
| KR890008150A (ko) | 1989-07-10 |
| DK616388A (da) | 1989-05-08 |
| FI885128A7 (fi) | 1989-05-08 |
| ZA888186B (en) | 1989-07-26 |
| DK616388D0 (da) | 1988-11-04 |
| DE3869907D1 (de) | 1992-05-14 |
| CN1033055A (zh) | 1989-05-24 |
| US5086049A (en) | 1992-02-04 |
| NO177934B (no) | 1995-09-11 |
| FI88618C (fi) | 1993-06-10 |
| ES2031569T3 (es) | 1992-12-16 |
| FI885128A0 (fi) | 1988-11-07 |
| DK172077B1 (da) | 1997-10-13 |
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