NO332574B1 - Preparat omfattende etylendicystein-ligander konjugert til en malrettende ligand, metode for syntetisering av en etylendicystein-ligand, anvendelse og sett - Google Patents
Preparat omfattende etylendicystein-ligander konjugert til en malrettende ligand, metode for syntetisering av en etylendicystein-ligand, anvendelse og sett Download PDFInfo
- Publication number
- NO332574B1 NO332574B1 NO20025729A NO20025729A NO332574B1 NO 332574 B1 NO332574 B1 NO 332574B1 NO 20025729 A NO20025729 A NO 20025729A NO 20025729 A NO20025729 A NO 20025729A NO 332574 B1 NO332574 B1 NO 332574B1
- Authority
- NO
- Norway
- Prior art keywords
- ligand
- 99mtc
- tumor
- ethylenedicysteine
- targeting ligand
- Prior art date
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- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
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- A61K51/0453—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
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- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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| US8043603B2 (en) | 2002-02-07 | 2011-10-25 | Endocyte, Inc. | Folate targeted enhanced tumor and folate receptor positive tissue optical imaging technology |
| US8043602B2 (en) | 2002-02-07 | 2011-10-25 | Endocyte, Inc. | Folate targeted enhanced tumor and folate receptor positive tissue optical imaging technology |
| CN1649628A (zh) * | 2002-02-26 | 2005-08-03 | 天藤制药株式会社 | 向脂质体中包封金属络合物的方法 |
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| US7824661B2 (en) | 2002-03-11 | 2010-11-02 | Molecular Insight Pharmaceuticals, Inc. | Technetium- and rhenium-bis(heteroaryl) complexes, and methods of use thereof |
| CN101648028B (zh) * | 2002-05-06 | 2012-11-21 | 恩多塞特公司 | 维生素-定向的显象剂 |
| CN101985443A (zh) * | 2002-11-07 | 2011-03-16 | 得克萨斯大学体系董事会 | 乙二半胱氨酸（ec）-药物结合物、组合物及用于组织特异性疾病显像的方法 |
| SI1592457T1 (sl) * | 2003-01-27 | 2012-12-31 | Endocyte, Inc. | Konjugat folat-vinblastin kot zdravilo |
| US9050378B2 (en) | 2003-12-10 | 2015-06-09 | Board Of Regents, The University Of Texas System | N2S2 chelate-targeting ligand conjugates |
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| EP1827239B1 (en) * | 2004-12-23 | 2019-04-17 | Purdue Research Foundation | Positron emission tomography imaging method |
| WO2006107794A2 (en) * | 2005-04-01 | 2006-10-12 | The Board Of Regents Of The University Of Texas System | Poly(peptide) as a chelator: methods of manufacture and uses |
| JP5175723B2 (ja) | 2005-07-05 | 2013-04-03 | パーデュー・リサーチ・ファウンデーション | 単球介在性疾患を治療するための組成物の調製 |
| US10925977B2 (en) * | 2006-10-05 | 2021-02-23 | Ceil>Point, LLC | Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications |
| EP2087337A4 (en) | 2006-11-03 | 2010-09-08 | Purdue Research Foundation | METHOD AND DEVICE FOR EX-VIVO FLOW CYTOMETRY |
| US20100104511A1 (en) * | 2006-11-22 | 2010-04-29 | The Board Of Regents Of The University Of Texas System | Methods and compositions using chelator-antibody conjugates |
| CA2677792C (en) | 2007-02-07 | 2015-04-14 | Purdue Research Foundation | Positron emission tomography imaging method |
| WO2008119036A2 (en) * | 2007-03-27 | 2008-10-02 | Radiomedix Inc. | Compositions for targeted imaging and therapy |
| CA2688308A1 (en) | 2007-05-25 | 2008-12-04 | Purdue Research Foundation | Method of imaging localized infections |
| WO2009120244A1 (en) * | 2008-03-24 | 2009-10-01 | The Board Of Regents Of The University Of Texas System | Image-guided therapy of myocardial disease: composition, manufacturing and applications |
| CN101721720B (zh) * | 2008-10-29 | 2011-08-24 | 阮建评 | 硝咪唑-氨基酸化合型核素乏氧造影剂及其前体 |
| US20110085969A1 (en) * | 2009-10-09 | 2011-04-14 | Rollo F David | Chelator-targeting ligand conjugates for cardiovascular imaging |
| US20110280770A1 (en) * | 2010-05-12 | 2011-11-17 | Jeffrey Lacy | Nanogenerator |
| CA2843313C (en) | 2011-06-20 | 2018-02-13 | Radiomedix Inc. | Compositions, methods of synthesis and use of carbohydrate targeted agents |
| PL2830666T3 (pl) | 2012-03-26 | 2021-03-08 | Board Of Regents, The University Of Texas System | Skuteczna synteza koniugatów etylenodicysteina-cukier do obrazowania i terapii |
| US9886546B2 (en) | 2012-11-20 | 2018-02-06 | General Electric Company | Methods and apparatus to label radiology images |
| EA035171B1 (ru) * | 2013-11-14 | 2020-05-08 | Эндосайт, Инк. | Конъюгаты на основе связывающихся с psma лигандов или ингибиторов psma для позитронно-эмиссионной томографии |
| ES2811347T3 (es) | 2015-08-14 | 2021-03-11 | Endocyte Inc | Método de formación de imágenes con un compuesto quelante |
| US10905783B2 (en) | 2015-11-27 | 2021-02-02 | Michal RIVLIN | Glucosamine and derivatives thereof in imaging |
| US20200276338A1 (en) * | 2017-09-19 | 2020-09-03 | The Governors Of The University Of Alberta | Bioreductively-activated compounds, their prodrugs, radiopharmaceuticals, the compositions, and their applications in multimodal theranostic management of hypoxia diseases including cancer |
| RU2692451C2 (ru) * | 2017-10-02 | 2019-06-24 | Федеральное государственное бюджетное научное учреждение "Томский национальный исследовательский медицинский центр" Российской академии наук ("Томский НИМЦ") | Способ радионуклидной диагностики опухолей головного мозга |
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