NO329816B1 - Antistoffer mot humant IL-10, anvendelse av disse, DNA konstruksjoner, ekspresjonsvektor, fremgangsmate for fremstilling og farmasoytisk sammensetning - Google Patents
Antistoffer mot humant IL-10, anvendelse av disse, DNA konstruksjoner, ekspresjonsvektor, fremgangsmate for fremstilling og farmasoytisk sammensetning Download PDFInfo
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Classifications
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- C07—ORGANIC CHEMISTRY
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- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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- C07K—PEPTIDES
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- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
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- Ophthalmology & Optometry (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0001448.0A GB0001448D0 (en) | 2000-01-21 | 2000-01-21 | Organic compounds |
| PCT/EP2001/000591 WO2001053353A2 (en) | 2000-01-21 | 2001-01-19 | Recombinant antibodies to human interkleukin-1 beta |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO20023266D0 NO20023266D0 (no) | 2002-07-05 |
| NO20023266L NO20023266L (no) | 2002-08-28 |
| NO329816B1 true NO329816B1 (no) | 2010-12-27 |
Family
ID=9884137
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20023266A NO329816B1 (no) | 2000-01-21 | 2002-07-05 | Antistoffer mot humant IL-10, anvendelse av disse, DNA konstruksjoner, ekspresjonsvektor, fremgangsmate for fremstilling og farmasoytisk sammensetning |
Country Status (33)
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| US (4) | US20030124617A1 (ko) |
| EP (1) | EP1248804B2 (ko) |
| JP (2) | JP3978338B2 (ko) |
| KR (1) | KR100697126B1 (ko) |
| CN (1) | CN1395581B (ko) |
| AR (1) | AR027253A1 (ko) |
| AT (1) | ATE346868T1 (ko) |
| AU (1) | AU772949B2 (ko) |
| BR (1) | BR0107661A (ko) |
| CA (1) | CA2396212C (ko) |
| CO (1) | CO5261584A1 (ko) |
| CY (1) | CY1107989T1 (ko) |
| CZ (1) | CZ302738B6 (ko) |
| DE (1) | DE60124863T3 (ko) |
| DK (1) | DK1248804T4 (ko) |
| ES (1) | ES2274865T5 (ko) |
| GB (1) | GB0001448D0 (ko) |
| HK (1) | HK1050013A1 (ko) |
| HU (1) | HUP0204156A3 (ko) |
| IL (2) | IL150551A0 (ko) |
| MX (1) | MXPA02007091A (ko) |
| MY (1) | MY155269A (ko) |
| NO (1) | NO329816B1 (ko) |
| NZ (1) | NZ519936A (ko) |
| PE (1) | PE20011219A1 (ko) |
| PL (1) | PL207642B1 (ko) |
| PT (1) | PT1248804E (ko) |
| RU (1) | RU2264413C2 (ko) |
| SI (1) | SI1248804T2 (ko) |
| SK (1) | SK288054B6 (ko) |
| TR (1) | TR200201780T2 (ko) |
| WO (1) | WO2001053353A2 (ko) |
| ZA (1) | ZA200205659B (ko) |
Families Citing this family (40)
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| GB0001448D0 (en) * | 2000-01-21 | 2000-03-08 | Novartis Ag | Organic compounds |
| MXPA02012867A (es) | 2000-06-29 | 2003-09-05 | Abbott Lab | Anticuerpos de especificidad doble y metodos para la elaboracion y el uso de los mismos. |
| GB0020685D0 (en) | 2000-08-22 | 2000-10-11 | Novartis Ag | Organic compounds |
| JP2005518789A (ja) * | 2002-01-28 | 2005-06-30 | メダレックス， インク． | 前立腺特異性膜抗原（ｐｓｍａ）に対するヒトモノクローナル抗体 |
| GB0303337D0 (en) | 2003-02-13 | 2003-03-19 | Celltech R&D Ltd | Biological products |
| EP1664796B1 (en) * | 2003-09-15 | 2010-12-15 | Oklahoma Medical Research Foundation | Method of using cytokine assays to diagnose, treat, and evaluate ankylosing spondylitis |
| WO2006121422A2 (en) | 2004-02-06 | 2006-11-16 | University Of Massachusetts | Antibodies against clostridium difficile toxins and uses thereof |
| EP1851245B1 (en) * | 2005-01-26 | 2012-10-10 | Amgen Fremont Inc. | Antibodies against interleukin-1 beta |
| JO3058B1 (ar) * | 2005-04-29 | 2017-03-15 | Applied Molecular Evolution Inc | الاجسام المضادة لمضادات -اي ال-6,تركيباتها طرقها واستعمالاتها |
| HUE029021T2 (en) | 2005-06-21 | 2017-02-28 | Xoma (Us) Llc | IL-1beta-binding antibodies and fragments thereof |
| US8105587B2 (en) * | 2005-10-26 | 2012-01-31 | Novartis Ag | Methods of treating arthritis using IL-1β binding molecules |
| EP1971366B1 (en) * | 2005-12-29 | 2014-07-30 | Janssen Biotech, Inc. | Human anti-il-23 antibodies, compositions, methods and uses |
| US7943328B1 (en) | 2006-03-03 | 2011-05-17 | Prometheus Laboratories Inc. | Method and system for assisting in diagnosing irritable bowel syndrome |
| EP2021026A1 (en) * | 2006-04-14 | 2009-02-11 | Novartis AG | Use of il-i antibodies for treating ophthalmic disorders |
| US20080085524A1 (en) * | 2006-08-15 | 2008-04-10 | Prometheus Laboratories Inc. | Methods for diagnosing irritable bowel syndrome |
| CA2673592C (en) * | 2006-12-20 | 2014-03-25 | Xoma Technology Ltd. | Methods for the treatment of il-1.beta. related diseases |
| US8324350B2 (en) * | 2006-12-29 | 2012-12-04 | Abbott Laboratories | Dual-specific IL-1α/IL-1β antibodies |
| AU2008219681A1 (en) | 2007-02-28 | 2008-09-04 | Merck Sharp & Dohme Corp. | Combination therapy for treatment of immune disorders |
| JP2010528086A (ja) * | 2007-05-29 | 2010-08-19 | ノバルティス アーゲー | 抗ｉｌ−１治療に関する新しい適応症 |
| DK2391650T3 (en) | 2007-12-20 | 2015-01-12 | Xoma Us Llc | Methods of treating gout |
| AU2009256072B2 (en) * | 2008-06-06 | 2015-05-28 | Xoma (Us) Llc | Methods for the treatment of rheumatoid arthritis |
| WO2010028273A1 (en) | 2008-09-05 | 2010-03-11 | Xoma Technology Ltd. | Methods for improvement of beta cell function |
| SI3202785T1 (sl) | 2009-10-26 | 2024-08-30 | F. Hoffmann-La Roche Ag | Postopek za proizvodnjo glikoziliranega imunoglobulina |
| CN102883748A (zh) * | 2010-05-07 | 2013-01-16 | 爱克索马技术有限公司 | 治疗IL-1β相关状况的方法 |
| DE102010033565B4 (de) * | 2010-07-27 | 2012-06-21 | Tetec Tissue Engineering Technologies Ag | Marker zur Bestimmung von Chondrozyten |
| KR102434557B1 (ko) | 2010-08-02 | 2022-08-23 | 리제너론 파아마슈티컬스, 인크. | Ｖｌ 도메인을 포함하는 결합 단백질을 생성하는 마우스 |
| US9085621B2 (en) | 2010-09-10 | 2015-07-21 | Apexigen, Inc. | Anti-IL-1β antibodies |
| PL2738259T3 (pl) * | 2011-02-25 | 2020-08-24 | Regeneron Pharmaceuticals, Inc. | Myszy adam6 |
| PT2739740T (pt) | 2011-08-05 | 2020-01-09 | Regeneron Pharma | Cadeia leve universal humanizada de murganhos |
| DE102011083595A1 (de) | 2011-09-28 | 2013-03-28 | Bayer Pharma AG | Inhibition der Wirkung von Interleukin 1 beta zur Behandlung der Endometriose |
| JP6320300B2 (ja) | 2011-12-19 | 2018-05-09 | ゾーマ （ユーエス） リミテッド ライアビリティ カンパニー | 座瘡を治療するための方法 |
| MX356429B (es) | 2011-12-20 | 2018-05-29 | Regeneron Pharma | Ratones con cadena ligera humanizada. |
| SI2814843T1 (sl) | 2012-02-13 | 2020-11-30 | Agency For Science, Technology And Research | IL-beta nevtralizirajoča humana monoklonska protitelesa |
| SG10201609277PA (en) | 2012-06-12 | 2017-01-27 | Regeneron Pharma | Humanized non-human animals with restricted immunoglobulin heavy chain loci |
| US20150266976A1 (en) | 2014-03-21 | 2015-09-24 | Regeneron Pharmaceuticals, Inc. | Vl antigen binding proteins exhibiting distinct binding characteristics |
| KR20210088756A (ko) | 2014-03-21 | 2021-07-14 | 리제너론 파마슈티칼스 인코포레이티드 | 단일 도메인 결합 단백질을 생산하는 비-인간 동물 |
| JP2018508224A (ja) | 2015-03-19 | 2018-03-29 | リジェネロン・ファーマシューティカルズ・インコーポレイテッドＲｅｇｅｎｅｒｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． | 抗原を結合する軽鎖可変領域を選択する非ヒト動物 |
| CN110818793A (zh) * | 2018-08-14 | 2020-02-21 | 中山康方生物医药有限公司 | 抗IL-1β的抗体、其药物组合物及其用途 |
| WO2020104943A2 (en) | 2018-11-20 | 2020-05-28 | Janssen Biotech, Inc. | Safe and effective method of treating psoriasis with anti-il-23 specific antibody |
| AU2020279987A1 (en) | 2019-05-23 | 2021-11-18 | Janssen Biotech, Inc. | Method of treating inflammatory bowel disease with a combination therapy of antibodies to IL-23 and TNF alpha |
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| US4772685A (en) | 1985-10-02 | 1988-09-20 | Merck & Co., Inc. | Immunogenic peptides of human interleukin-1 and the corresponding anti-peptide antibodies |
| US4935343A (en) * | 1986-08-08 | 1990-06-19 | Syntex (U.S.A.) Inc. | Monoclonal antibodies for interleukin-1β |
| FR2640146B1 (fr) * | 1988-12-08 | 1993-12-24 | Commissariat A Energie Atomique | Anticorps monoclonaux anti-interleukines 1(alpha) et 1(beta), leur procede de production et applications desdits anticorps a la detection des interleukines 1(alpha) et 1(beta) et en therapeutique |
| US5859205A (en) * | 1989-12-21 | 1999-01-12 | Celltech Limited | Humanised antibodies |
| GB8928874D0 (en) | 1989-12-21 | 1990-02-28 | Celltech Ltd | Humanised antibodies |
| GB9014932D0 (en) | 1990-07-05 | 1990-08-22 | Celltech Ltd | Recombinant dna product and method |
| JP3714683B2 (ja) * | 1992-07-30 | 2005-11-09 | 生化学工業株式会社 | 抗リウマチ剤 |
| US5429614A (en) | 1993-06-30 | 1995-07-04 | Baxter International Inc. | Drug delivery system |
| WO1995001997A1 (en) * | 1993-07-09 | 1995-01-19 | Smithkline Beecham Corporation | RECOMBINANT AND HUMANIZED IL-1β ANTIBODIES FOR TREATMENT OF IL-1 MEDIATED INFLAMMATORY DISORDERS IN MAN |
| US6051228A (en) | 1998-02-19 | 2000-04-18 | Bristol-Myers Squibb Co. | Antibodies against human CD40 |
| GB0001448D0 (en) * | 2000-01-21 | 2000-03-08 | Novartis Ag | Organic compounds |
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- 2001-01-19 CA CA2396212A patent/CA2396212C/en not_active Expired - Fee Related
- 2001-01-19 AT AT01905671T patent/ATE346868T1/de active
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2003
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2007
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