NO324949B1 - Fremgangsmate for fremstilling av dibenzo[b,f]azepiner - Google Patents

Fremgangsmate for fremstilling av dibenzo[b,f]azepiner

Info

Publication number
NO324949B1
NO324949B1 NO20023575A NO20023575A NO324949B1 NO 324949 B1 NO324949 B1 NO 324949B1 NO 20023575 A NO20023575 A NO 20023575A NO 20023575 A NO20023575 A NO 20023575A NO 324949 B1 NO324949 B1 NO 324949B1
Authority
NO
Norway
Prior art keywords
azepines
dibenzo
preparation
Prior art date
Application number
NO20023575A
Other languages
English (en)
Norwegian (no)
Other versions
NO20023575D0 (no
NO20023575L (no
Inventor
Peter Fuenfschilling
Daniel Kaufmann
Olivier Lohse
Ulrich Beutler
Werner Zaugg
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9885081&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO324949(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of NO20023575D0 publication Critical patent/NO20023575D0/no
Publication of NO20023575L publication Critical patent/NO20023575L/no
Publication of NO324949B1 publication Critical patent/NO324949B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
    • C07D223/22—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines
    • C07D223/24—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom
    • C07D223/26—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom having a double bond between positions 10 and 11
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
    • C07D223/22—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/30—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having the nitrogen atom of the carboxamide group bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/26—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a six-membered aromatic ring
    • C07C271/28—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a six-membered aromatic ring to a carbon atom of a non-condensed six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
    • C07D223/22—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines
    • C07D223/24—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom
    • C07D223/28—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom having a single bond between positions 10 and 11

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Epoxy Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
NO20023575A 2000-02-07 2002-07-26 Fremgangsmate for fremstilling av dibenzo[b,f]azepiner NO324949B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0002740.9A GB0002740D0 (en) 2000-02-07 2000-02-07 Organic compounds
PCT/EP2001/001330 WO2001056992A2 (en) 2000-02-07 2001-02-07 Dibenzo (b,f) azepine intermediates

Publications (3)

Publication Number Publication Date
NO20023575D0 NO20023575D0 (no) 2002-07-26
NO20023575L NO20023575L (no) 2002-07-26
NO324949B1 true NO324949B1 (no) 2008-01-14

Family

ID=9885081

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20023575A NO324949B1 (no) 2000-02-07 2002-07-26 Fremgangsmate for fremstilling av dibenzo[b,f]azepiner

Country Status (33)

Country Link
US (1) US7112673B2 (cs)
EP (2) EP1265868B1 (cs)
JP (1) JP4859322B2 (cs)
KR (5) KR20020071033A (cs)
CN (2) CN1244563C (cs)
AR (2) AR029442A1 (cs)
AT (2) ATE505459T1 (cs)
AU (1) AU767724B2 (cs)
BR (1) BR0107922A (cs)
CA (3) CA2639210C (cs)
CO (1) CO5271705A1 (cs)
CY (1) CY1111567T1 (cs)
CZ (1) CZ301572B6 (cs)
DE (2) DE60144456D1 (cs)
DK (1) DK2067772T3 (cs)
ES (2) ES2324900T3 (cs)
GB (1) GB0002740D0 (cs)
HU (1) HU229420B1 (cs)
IL (3) IL150613A0 (cs)
MX (1) MXPA02007629A (cs)
MY (1) MY136474A (cs)
NO (1) NO324949B1 (cs)
NZ (1) NZ520329A (cs)
PE (1) PE20011078A1 (cs)
PL (2) PL217225B1 (cs)
PT (2) PT1265868E (cs)
RU (1) RU2303591C2 (cs)
SI (1) SI2067772T1 (cs)
SK (1) SK287217B6 (cs)
TR (1) TR200201655T2 (cs)
TW (1) TWI284638B (cs)
WO (1) WO2001056992A2 (cs)
ZA (1) ZA200206219B (cs)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2407173C (en) 2001-10-09 2009-09-29 Max India Limited Process for the preparation of 10-methoxycarbamazepine
EP1302464A1 (en) * 2001-10-09 2003-04-16 Max India Limited Process for preparation of 10-methoxycarbamazepine
EP1513816A4 (en) * 2002-06-14 2009-12-16 Taro Pharmaceuticals Usa Inc PROCESS FOR THE PRODUCTION OF 5H-DIBENZ (B, F) AZEPINE-5-CARBOXAMIDE
ITMI20040452A1 (it) 2004-03-09 2004-06-09 Clariant Lsm Italia Spa Processo per la preparazione di oxcarbazepina
GEP20115364B (en) 2005-05-10 2011-12-26 Intermune Inc Method for modulation of stress-activated protein kinase system
WO2007127630A1 (en) * 2006-04-26 2007-11-08 Supernus Pharmaceuticals, Inc Controlled released preparations of oxcarbazepine having sigmoidal release profile
US20090082335A1 (en) * 2007-09-26 2009-03-26 Protia, Llc Deuterium-enriched oxcarbazepine
MX2010012848A (es) 2008-06-03 2011-03-01 Intermune Inc Compuestos y metodos para tratar trastornos inflamatorios y fibroticos.
IN2015DN02296A (cs) 2012-09-26 2015-08-21 Ranbaxy Lab Ltd
AR092742A1 (es) 2012-10-02 2015-04-29 Intermune Inc Piridinonas antifibroticas
US11465978B2 (en) 2013-09-11 2022-10-11 The Administrators Of The Tulane Educational Fund Anthranilic amides and the use thereof
CN110452216B (zh) 2014-04-02 2022-08-26 英特穆恩公司 抗纤维化吡啶酮类

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4847374A (en) * 1987-01-27 1989-07-11 Ciba-Geigy Corporation Process for the manufacture of N,N-(Dibenzohexatrienylene)ureas
DE4305502A1 (de) * 1993-02-23 1994-08-25 Basf Ag Ortho-substituierte 2-Methoxyiminophenylessigsäuremethylamide
IT1272897B (it) 1995-01-13 1997-07-01 I F C Iniziative Finanziaarie Processo per la produzione di 10-oxo-10,11-diidro-sh- -dibenz(b,f) azepin-5-carbossiammide
US6355680B1 (en) * 1996-02-20 2002-03-12 Exocell, Inc. Albumin-binding compounds that prevent nonenzymatic glycation and that may be used for treatment of glycation-related pathologies
IT1283594B1 (it) 1996-04-12 1998-04-22 Trifarma Srl Derivati della 5h-dibenz- (b,f)-azepin-5-carbossiammide, loro preparazione e uso come sostanze ad azione medicinale
AU756586C (en) * 1997-07-01 2004-01-29 Warner-Lambert Company 2-(4-bromo or 4-iodo phenylamino) benzoic acid derivatives and their use as MEK inhibitors
US6048856A (en) 1997-12-17 2000-04-11 Novo Nordisk A/S Heterocyclic compounds

Also Published As

Publication number Publication date
CY1111567T1 (el) 2015-10-07
EP2067772A2 (en) 2009-06-10
RU2002123334A (ru) 2004-01-10
BR0107922A (pt) 2002-10-22
CA2724295C (en) 2011-07-26
ATE505459T1 (de) 2011-04-15
AU4237301A (en) 2001-08-14
PE20011078A1 (es) 2001-11-16
CN1394204A (zh) 2003-01-29
AR079237A2 (es) 2012-01-04
CA2639210C (en) 2011-05-03
IL150613A (en) 2010-05-17
KR20100018069A (ko) 2010-02-16
CA2395601C (en) 2010-01-05
KR100931753B1 (ko) 2009-12-14
NZ520329A (en) 2003-11-28
EP1265868A2 (en) 2002-12-18
CZ301572B6 (cs) 2010-04-21
RU2303591C2 (ru) 2007-07-27
CA2639210A1 (en) 2001-08-09
PT2067772E (pt) 2011-07-13
CN100455572C (zh) 2009-01-28
KR20090102882A (ko) 2009-09-30
KR20080003016A (ko) 2008-01-04
JP4859322B2 (ja) 2012-01-25
NO20023575D0 (no) 2002-07-26
PL392476A1 (pl) 2010-11-22
HUP0300243A3 (en) 2005-07-28
AU767724B2 (en) 2003-11-20
SK11262002A3 (sk) 2003-02-04
HU229420B1 (en) 2013-12-30
PT1265868E (pt) 2009-07-15
ES2363490T3 (es) 2011-08-05
KR20080103608A (ko) 2008-11-27
DK2067772T3 (da) 2011-07-18
CA2724295A1 (en) 2001-08-09
GB0002740D0 (en) 2000-03-29
HK1052501A1 (en) 2003-09-19
EP2067772B1 (en) 2011-04-13
IL150613A0 (en) 2003-02-12
CO5271705A1 (es) 2003-04-30
EP2067772A3 (en) 2009-08-19
KR20020071033A (ko) 2002-09-11
PL214039B1 (pl) 2013-06-28
JP2003521536A (ja) 2003-07-15
CN1721409A (zh) 2006-01-18
HUP0300243A2 (hu) 2003-06-28
TR200201655T2 (tr) 2002-11-21
ZA200206219B (en) 2003-04-04
US7112673B2 (en) 2006-09-26
MXPA02007629A (es) 2002-12-13
US20030032800A1 (en) 2003-02-13
AR029442A1 (es) 2003-06-25
KR101216285B1 (ko) 2012-12-28
PL217225B1 (pl) 2014-06-30
NO20023575L (no) 2002-07-26
ATE427938T1 (de) 2009-04-15
SK287217B6 (sk) 2010-03-08
WO2001056992A3 (en) 2002-01-24
WO2001056992A2 (en) 2001-08-09
SI2067772T1 (sl) 2011-08-31
PL356404A1 (en) 2004-06-28
CA2395601A1 (en) 2001-08-09
EP1265868B1 (en) 2009-04-08
TWI284638B (en) 2007-08-01
IL188183A (en) 2011-02-28
CN1244563C (zh) 2006-03-08
CZ20022676A3 (cs) 2002-11-13
DE60144456D1 (de) 2011-05-26
MY136474A (en) 2008-10-31
ES2324900T3 (es) 2009-08-19
KR100966209B1 (ko) 2010-06-25
DE60138271D1 (de) 2009-05-20

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Legal Events

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MM1K Lapsed by not paying the annual fees