IT1272897B - Processo per la produzione di 10-oxo-10,11-diidro-sh- -dibenz(b,f) azepin-5-carbossiammide - Google Patents

Processo per la produzione di 10-oxo-10,11-diidro-sh- -dibenz(b,f) azepin-5-carbossiammide

Info

Publication number
IT1272897B
IT1272897B ITMI950056A ITMI950056A IT1272897B IT 1272897 B IT1272897 B IT 1272897B IT MI950056 A ITMI950056 A IT MI950056A IT MI950056 A ITMI950056 A IT MI950056A IT 1272897 B IT1272897 B IT 1272897B
Authority
IT
Italy
Prior art keywords
pct
dibenz
azepin
carbamoylation
sec
Prior art date
Application number
ITMI950056A
Other languages
English (en)
Inventor
Alberto Milanese
Original Assignee
I F C Iniziative Finanziaarie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by I F C Iniziative Finanziaarie filed Critical I F C Iniziative Finanziaarie
Publication of ITMI950056A0 publication Critical patent/ITMI950056A0/it
Priority to ITMI950056A priority Critical patent/IT1272897B/it
Priority to AU43479/96A priority patent/AU4347996A/en
Priority to ES96900104T priority patent/ES2150093T3/es
Priority to PCT/EP1996/000004 priority patent/WO1996021649A1/en
Priority to PT96900104T priority patent/PT847390E/pt
Priority to EP96900104A priority patent/EP0847390B1/en
Priority to AT96900104T priority patent/ATE195518T1/de
Priority to DE69609843T priority patent/DE69609843T2/de
Priority to DK96900104T priority patent/DK0847390T3/da
Priority to US08/765,481 priority patent/US5808058A/en
Publication of ITMI950056A1 publication Critical patent/ITMI950056A1/it
Application granted granted Critical
Publication of IT1272897B publication Critical patent/IT1272897B/it
Priority to GR20000402532T priority patent/GR3034844T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
    • C07D223/22—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines
ITMI950056A 1995-01-13 1995-01-13 Processo per la produzione di 10-oxo-10,11-diidro-sh- -dibenz(b,f) azepin-5-carbossiammide IT1272897B (it)

Priority Applications (11)

Application Number Priority Date Filing Date Title
ITMI950056A IT1272897B (it) 1995-01-13 1995-01-13 Processo per la produzione di 10-oxo-10,11-diidro-sh- -dibenz(b,f) azepin-5-carbossiammide
AT96900104T ATE195518T1 (de) 1995-01-13 1996-01-03 Verfahren zur herstellung von 10-oxo-10, 11- dihydro-5h-dibenz(b,f)azepin-5-carboxamid
ES96900104T ES2150093T3 (es) 1995-01-13 1996-01-03 Procedimiento para la preparacion de 10-oxo-10,11-dihidro-5h-dibenz(b,f)acepin-5-carboxamida.
PCT/EP1996/000004 WO1996021649A1 (en) 1995-01-13 1996-01-03 A PROCESS FOR THE PREPARATION OF 10-OXO-10,11-DIHYDRO-5H-DIBENZ(b,f)AZEPIN-5-CARBOXAMIDE
PT96900104T PT847390E (pt) 1995-01-13 1996-01-03 Processo para a preparacaode 10-oxo-10,11-di-hidro-5h-dibenz(b,f)azepin-5-carboxamida
EP96900104A EP0847390B1 (en) 1995-01-13 1996-01-03 A PROCESS FOR THE PREPARATION OF 10-OXO-10,11-DIHYDRO-5H-DIBENZ(b,f)AZEPIN-5-CARBOXAMIDE
AU43479/96A AU4347996A (en) 1995-01-13 1996-01-03 A process for the preparation of 10-oxo-10,11-dihydro-5h-dibenz(b,f)azepin-5-carboxamide
DE69609843T DE69609843T2 (de) 1995-01-13 1996-01-03 Verfahren zur herstellung von 10-oxo-10, 11-dihydro-5h-dibenz(b,f)azepin-5-carboxamid
DK96900104T DK0847390T3 (da) 1995-01-13 1996-01-03 Fremgangsmåde til fremstilling af 10-oxo-10,11-dihydro-5H-dibenz(b,f)azepin-5-carboxamid
US08/765,481 US5808058A (en) 1995-01-13 1996-01-03 Process for the preparation of 10-OXO-10, 11-dihydro-5H-dibenz (b,f) azepin-5-carboxamide
GR20000402532T GR3034844T3 (en) 1995-01-13 2000-11-14 A PROCESS FOR THE PREPARATION OF 10-OXO-10,11-DIHYDRO-5H-DIBENZ(b,f)AZEPIN-5-CARBOXAMIDE

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI950056A IT1272897B (it) 1995-01-13 1995-01-13 Processo per la produzione di 10-oxo-10,11-diidro-sh- -dibenz(b,f) azepin-5-carbossiammide

Publications (3)

Publication Number Publication Date
ITMI950056A0 ITMI950056A0 (it) 1995-01-13
ITMI950056A1 ITMI950056A1 (it) 1996-07-13
IT1272897B true IT1272897B (it) 1997-07-01

Family

ID=11370213

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI950056A IT1272897B (it) 1995-01-13 1995-01-13 Processo per la produzione di 10-oxo-10,11-diidro-sh- -dibenz(b,f) azepin-5-carbossiammide

Country Status (11)

Country Link
US (1) US5808058A (it)
EP (1) EP0847390B1 (it)
AT (1) ATE195518T1 (it)
AU (1) AU4347996A (it)
DE (1) DE69609843T2 (it)
DK (1) DK0847390T3 (it)
ES (1) ES2150093T3 (it)
GR (1) GR3034844T3 (it)
IT (1) IT1272897B (it)
PT (1) PT847390E (it)
WO (1) WO1996021649A1 (it)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT408224B (de) * 1999-03-15 2001-09-25 Dsm Fine Chem Austria Gmbh Verfahren zur herstellung von oxcarbazepin
GB0002740D0 (en) * 2000-02-07 2000-03-29 Novartis Ag Organic compounds
JP2004526706A (ja) * 2001-02-12 2004-09-02 テバ ファーマシューティカル インダストリーズ リミティド オクスカルバゼピンの新しい結晶形態及びそれらの調製方法
GB0112812D0 (en) * 2001-05-25 2001-07-18 Portela & Ca Sa Mthd for preparation of 10, 11-dihydro-10-hydroxy-5H-dibenz/B,F/azepine-5-c arboxamide and 10,11-dihydro-10-oxo-5H-dibenz/B,F/azepine-5-carb oxamide therefrom
CA2407173C (en) 2001-10-09 2009-09-29 Max India Limited Process for the preparation of 10-methoxycarbamazepine
EP1302464A1 (en) * 2001-10-09 2003-04-16 Max India Limited Process for preparation of 10-methoxycarbamazepine
WO2003106414A2 (en) 2002-06-14 2003-12-24 Taro Pharmaceuticals U.S.A., Inc. Method of preparing a 5h-dibenz[b,f]azepine-5-carboxamide
EP1678140A2 (en) * 2003-10-20 2006-07-12 Amoli Organics Ltd. Novel process for preparation of 10-oxo-10, 11-dihydro-5h-dibenz [b,f]azepine-5-carboxamide (oxcarbazepine) via intermediate, 10-methoxy-5h-dibenz [b,f] azepine-5-carbonylchloride
ITMI20040452A1 (it) * 2004-03-09 2004-06-09 Clariant Lsm Italia Spa Processo per la preparazione di oxcarbazepina
US7459553B2 (en) * 2004-03-11 2008-12-02 Glenmark Generics Ltd. Process for the preparation of carboxamide compounds
US7982032B2 (en) * 2004-03-11 2011-07-19 Sun Pharmaceutical Industries Limited Process for the preparation of 10,11-dihydro-10-oxo-5H-dibenz[b,f]azepine-5-carboxamide
CA2471666C (en) * 2004-06-18 2009-10-13 Apotex Pharmachem Inc. An improved process for the preparation of oxcarbazepine and related intermediates
US20070032647A1 (en) * 2004-10-15 2007-02-08 Amoli Organics Ltd. Novel process for preparation of 10-oxo-10, 11-dihydro-5h-dibenz [b,f] azepine-5-carbox- amide (oxcarbazepine) via intermediate, 10-methoxy-5h-debenz[b,f] azepine-5-carbonyl- chloride
GB2422149A (en) 2005-01-14 2006-07-19 Portela & Ca Sa Process for the preparation of 10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide
EP2359830B1 (en) * 2006-04-26 2012-09-19 Supernus Pharmaceuticals, Inc. Controlled released preparations of oxcarbazepine having sigmoidal release profile
WO2007141798A1 (en) * 2006-06-07 2007-12-13 Jubilant Organosys Limited Process for producing oxcarbazepine via an 11-alkoxy-10-halo-dihydroiminostilbene intermediate
CA2658675A1 (en) * 2006-07-24 2008-01-31 Jubilant Organosys Limited Process for producing 10-oxo-10, 11-dihydr0-5h-dibenz [b, f] azepine-5-carboxamide starting from 5-cyanoiminostilbene
WO2009139001A2 (en) * 2008-05-08 2009-11-19 Matrix Laboratories Ltd An improved process for the preparation of oxcarbazepine
EP2697662B1 (en) 2011-04-13 2018-06-06 Codexis, Inc. Biocatalytic process for preparing eslicarbazepine and analogs thereof
US20150065704A1 (en) 2011-07-13 2015-03-05 Ketan Hirpara Process for the preparation and purification of eslicarbazepine acetate and intermediates thereof
WO2014049550A1 (en) 2012-09-26 2014-04-03 Ranbaxy Laboratories Limited Process for the preparation of oxcarbazepine and its use as intermediate in the preparation of eslicarbazepine acetate

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH500196A (de) * 1969-03-10 1970-12-15 Ciba Geigy Ag Verfahren zur Herstellung von neuen Azepinderivaten
FR2045705A1 (en) * 1969-06-24 1971-03-05 Rhone Poulenc Sa Fungicidal dihydrodibenzaxepine derivs
US4847374A (en) * 1987-01-27 1989-07-11 Ciba-Geigy Corporation Process for the manufacture of N,N-(Dibenzohexatrienylene)ureas
DE4307181C1 (de) * 1993-03-08 1994-11-10 Dresden Arzneimittel Verfahren zur Herstellung von 5H-Dibenz/b,f/azepin-5-carboxamid

Also Published As

Publication number Publication date
ATE195518T1 (de) 2000-09-15
PT847390E (pt) 2000-11-30
GR3034844T3 (en) 2001-02-28
DK0847390T3 (da) 2000-11-06
ITMI950056A0 (it) 1995-01-13
EP0847390A1 (en) 1998-06-17
WO1996021649A1 (en) 1996-07-18
EP0847390B1 (en) 2000-08-16
AU4347996A (en) 1996-07-31
ES2150093T3 (es) 2000-11-16
DE69609843D1 (de) 2000-09-21
US5808058A (en) 1998-09-15
DE69609843T2 (de) 2001-01-18
ITMI950056A1 (it) 1996-07-13

Similar Documents

Publication Publication Date Title
IT1272897B (it) Processo per la produzione di 10-oxo-10,11-diidro-sh- -dibenz(b,f) azepin-5-carbossiammide
DE59507973D1 (de) Verfahren zur herstellung von umhüllten tabletten
ATE170216T1 (de) Bruch- und lagerstabile, polyfunktionelle reinigungstabletten, verfahren zu ihrer herstellung und ihre verwendung
DE68904326T3 (de) Physiologisch aktive Substanzen enthaltende Mikrosphären des Polymilchsäuretyps sowie Verfahren zu deren Herstellung.
BR9105939A (pt) Processo para a producao simultanea de xilitol e etanol
MY109052A (en) Method for preparing biodegradable films from plant- based raw materials
ATE287258T1 (de) Verfahren zur herstellung von liposomen
WO1995024497A3 (en) Enzymatic preparation of polysaccharides
DE69823662D1 (de) 1,4,7,10-tetraazabicyclo(8.2.2)tetradecan-2-on, verfahren zu ihrer herstellung und ihrer verwendung für die herstellung von tetraazamacrocyclen
ATE178316T1 (de) Verfahren zur herstellung von aminoalkylguanidinen
MX169967B (es) Procedimiento para la produccion de gama butirolactona
PL319692A1 (en) Method of obtaining substituted 3-amino benzonitriles
NL1000276C2 (nl) Werkwijze ter vervaardiging van vezels uit poly(p-fenyleen- tereftaalamide).
ATE200485T1 (de) Verfahren zur herstellung und isolierung von atracurium besylate
GR3031588T3 (en) Process for preparing (s) (+)-4,4'-(1-methyl-1,2-ethanediyl)-bis(2,6-piperazinedione).
BR9807458A (pt) Processo para produzir ácido láctico e seus produtos.
ATE222585T1 (de) Verfahren zur herstellung von 4-hydroxy-2- pyrrolidon
DE59803194D1 (de) Verfahren zur herstellung von 1,3-disubstituierten 2-nitroguanidinen
DE69627533D1 (de) Herstellung von einem kristallinen amoxicillinsalz
ES2038616T3 (es) Un procedimiento para preparar 2,3-dihidro-1-(8-metil-1,2,4-triazolo(4,3-b)piridazin-6-il)-4-(1h)-piridinona.
EP0901996A4 (en) METHOD FOR PRODUCING OPTICALLY ACTIVE AMINES
DE69613101D1 (de) Verfahren zur herstellung von palatinitol
DE69618340T2 (de) Verfahren zur herstellung von substituierten anthrachinonen und deren verwendung zur herstellung von rheinen
EP0528694A3 (en) Method for producing optically active 3-substituted-2-norbornanones and their intermediates
ATE180765T1 (de) Verfahren zur reduktion von aminosäuren und deren derivaten

Legal Events

Date Code Title Description
0001 Granted