ATE195518T1 - Verfahren zur herstellung von 10-oxo-10, 11- dihydro-5h-dibenz(b,f)azepin-5-carboxamid - Google Patents

Verfahren zur herstellung von 10-oxo-10, 11- dihydro-5h-dibenz(b,f)azepin-5-carboxamid

Info

Publication number
ATE195518T1
ATE195518T1 AT96900104T AT96900104T ATE195518T1 AT E195518 T1 ATE195518 T1 AT E195518T1 AT 96900104 T AT96900104 T AT 96900104T AT 96900104 T AT96900104 T AT 96900104T AT E195518 T1 ATE195518 T1 AT E195518T1
Authority
AT
Austria
Prior art keywords
pct
dibenz
azepine
carboxamide
dihydro
Prior art date
Application number
AT96900104T
Other languages
English (en)
Inventor
Alberto Milanese
Original Assignee
Four Plus One Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Four Plus One Limited filed Critical Four Plus One Limited
Application granted granted Critical
Publication of ATE195518T1 publication Critical patent/ATE195518T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
    • C07D223/22—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT96900104T 1995-01-13 1996-01-03 Verfahren zur herstellung von 10-oxo-10, 11- dihydro-5h-dibenz(b,f)azepin-5-carboxamid ATE195518T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITMI950056A IT1272897B (it) 1995-01-13 1995-01-13 Processo per la produzione di 10-oxo-10,11-diidro-sh- -dibenz(b,f) azepin-5-carbossiammide
PCT/EP1996/000004 WO1996021649A1 (en) 1995-01-13 1996-01-03 A PROCESS FOR THE PREPARATION OF 10-OXO-10,11-DIHYDRO-5H-DIBENZ(b,f)AZEPIN-5-CARBOXAMIDE

Publications (1)

Publication Number Publication Date
ATE195518T1 true ATE195518T1 (de) 2000-09-15

Family

ID=11370213

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96900104T ATE195518T1 (de) 1995-01-13 1996-01-03 Verfahren zur herstellung von 10-oxo-10, 11- dihydro-5h-dibenz(b,f)azepin-5-carboxamid

Country Status (11)

Country Link
US (1) US5808058A (de)
EP (1) EP0847390B1 (de)
AT (1) ATE195518T1 (de)
AU (1) AU4347996A (de)
DE (1) DE69609843T2 (de)
DK (1) DK0847390T3 (de)
ES (1) ES2150093T3 (de)
GR (1) GR3034844T3 (de)
IT (1) IT1272897B (de)
PT (1) PT847390E (de)
WO (1) WO1996021649A1 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT408224B (de) * 1999-03-15 2001-09-25 Dsm Fine Chem Austria Gmbh Verfahren zur herstellung von oxcarbazepin
GB0002740D0 (en) * 2000-02-07 2000-03-29 Novartis Ag Organic compounds
IL157351A0 (en) * 2001-02-12 2004-02-19 Teva Pharma New crystal forms of oxcarbazepine and processes for their preparation
GB0112812D0 (en) * 2001-05-25 2001-07-18 Portela & Ca Sa Mthd for preparation of 10, 11-dihydro-10-hydroxy-5H-dibenz/B,F/azepine-5-c arboxamide and 10,11-dihydro-10-oxo-5H-dibenz/B,F/azepine-5-carb oxamide therefrom
US6670472B2 (en) 2001-10-09 2003-12-30 Max India Limited Process for the preparation of 10-methoxycarbamazepine
EP1302464A1 (de) * 2001-10-09 2003-04-16 Max India Limited Verfahren zur Herstellung von 10-Methoxycarbamazepin
CA2486560A1 (en) * 2002-06-14 2003-12-24 Taro Pharmaceuticals U.S.A., Inc. Method of preparing a 5h-dibenz[b,f]azepine-5-carboxamide
EP1678140A2 (de) * 2003-10-20 2006-07-12 Amoli Organics Ltd. Neues verfahren zur herstellung von 10-oxo-10,11-dihydro-5h-dibenz[ b,f] azepin-5-carbonsäureamid (oxcarbazepin) über das 10-methoxy-5h-dibenz[b,f]azepin-5-carbonylchlorid-zwischenprodukt
ITMI20040452A1 (it) * 2004-03-09 2004-06-09 Clariant Lsm Italia Spa Processo per la preparazione di oxcarbazepina
US7459553B2 (en) * 2004-03-11 2008-12-02 Glenmark Generics Ltd. Process for the preparation of carboxamide compounds
WO2005096709A2 (en) * 2004-03-11 2005-10-20 Sun Pharmaceutical Industries Limited A process for the preparation of 10,11-dihydro-10-oxo-5h-dibenz[b,f]azepine-5-carboxamide
CA2471666C (en) * 2004-06-18 2009-10-13 Apotex Pharmachem Inc. An improved process for the preparation of oxcarbazepine and related intermediates
US20070032647A1 (en) * 2004-10-15 2007-02-08 Amoli Organics Ltd. Novel process for preparation of 10-oxo-10, 11-dihydro-5h-dibenz [b,f] azepine-5-carbox- amide (oxcarbazepine) via intermediate, 10-methoxy-5h-debenz[b,f] azepine-5-carbonyl- chloride
GB2422149A (en) * 2005-01-14 2006-07-19 Portela & Ca Sa Process for the preparation of 10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide
MX2008013675A (es) * 2006-04-26 2009-03-06 Supernus Pharmaceuticals Inc Preparaciones de liberacion controlada de oxcarbacepina que tienen perfil de liberacion sigmoidal.
WO2007141798A1 (en) * 2006-06-07 2007-12-13 Jubilant Organosys Limited Process for producing oxcarbazepine via an 11-alkoxy-10-halo-dihydroiminostilbene intermediate
WO2008012837A1 (en) * 2006-07-24 2008-01-31 Jubilant Organosys Limited Process for producing 10-oxo-l10, 11-dihydr0-5h-dibenz [b, f] azepine-5-carboxamide starting from 5-cyanoiminostilbene
US8530647B2 (en) * 2008-05-08 2013-09-10 Mylan Laboratories Limited Process for the preparation of oxcarbazepine
EP2697662B1 (de) 2011-04-13 2018-06-06 Codexis, Inc. Biokatalytisches verfahren zur herstellung von eslicarbazepin und analoga davon
US20150065704A1 (en) 2011-07-13 2015-03-05 Ketan Hirpara Process for the preparation and purification of eslicarbazepine acetate and intermediates thereof
WO2014049550A1 (en) 2012-09-26 2014-04-03 Ranbaxy Laboratories Limited Process for the preparation of oxcarbazepine and its use as intermediate in the preparation of eslicarbazepine acetate

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH500196A (de) * 1969-03-10 1970-12-15 Ciba Geigy Ag Verfahren zur Herstellung von neuen Azepinderivaten
FR2045705A1 (en) * 1969-06-24 1971-03-05 Rhone Poulenc Sa Fungicidal dihydrodibenzaxepine derivs
US4847374A (en) * 1987-01-27 1989-07-11 Ciba-Geigy Corporation Process for the manufacture of N,N-(Dibenzohexatrienylene)ureas
DE4307181C1 (de) * 1993-03-08 1994-11-10 Dresden Arzneimittel Verfahren zur Herstellung von 5H-Dibenz/b,f/azepin-5-carboxamid

Also Published As

Publication number Publication date
DK0847390T3 (da) 2000-11-06
US5808058A (en) 1998-09-15
IT1272897B (it) 1997-07-01
DE69609843T2 (de) 2001-01-18
ITMI950056A0 (it) 1995-01-13
PT847390E (pt) 2000-11-30
ES2150093T3 (es) 2000-11-16
EP0847390A1 (de) 1998-06-17
WO1996021649A1 (en) 1996-07-18
EP0847390B1 (de) 2000-08-16
GR3034844T3 (en) 2001-02-28
ITMI950056A1 (it) 1996-07-13
AU4347996A (en) 1996-07-31
DE69609843D1 (de) 2000-09-21

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