DE69627533D1 - Herstellung von einem kristallinen amoxicillinsalz - Google Patents

Herstellung von einem kristallinen amoxicillinsalz

Info

Publication number
DE69627533D1
DE69627533D1 DE69627533T DE69627533T DE69627533D1 DE 69627533 D1 DE69627533 D1 DE 69627533D1 DE 69627533 T DE69627533 T DE 69627533T DE 69627533 T DE69627533 T DE 69627533T DE 69627533 D1 DE69627533 D1 DE 69627533D1
Authority
DE
Germany
Prior art keywords
salt
production
pct
crystalline
amoxicilline
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69627533T
Other languages
English (en)
Other versions
DE69627533T2 (de
Inventor
Joan Cabre
Jose Diago
Asuncion Esteve
Johannes Ludescher
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Biochemie GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9521921.8A external-priority patent/GB9521921D0/en
Priority claimed from GBGB9611088.7A external-priority patent/GB9611088D0/en
Application filed by Biochemie GmbH filed Critical Biochemie GmbH
Publication of DE69627533D1 publication Critical patent/DE69627533D1/de
Application granted granted Critical
Publication of DE69627533T2 publication Critical patent/DE69627533T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DE69627533T 1995-10-26 1996-10-28 Herstellung von einem kristallinen amoxicillinsalz Expired - Lifetime DE69627533T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9521921.8A GB9521921D0 (en) 1995-10-26 1995-10-26 Organic compounds
GBGB9611088.7A GB9611088D0 (en) 1996-05-28 1996-05-28 Organic compounds
PCT/EP1996/004682 WO1997015579A1 (en) 1995-10-26 1996-10-28 Production of a crystalline salt of amoxicillin

Publications (2)

Publication Number Publication Date
DE69627533D1 true DE69627533D1 (de) 2003-05-22
DE69627533T2 DE69627533T2 (de) 2003-12-18

Family

ID=26308006

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69627533T Expired - Lifetime DE69627533T2 (de) 1995-10-26 1996-10-28 Herstellung von einem kristallinen amoxicillinsalz

Country Status (11)

Country Link
US (1) US6103897A (de)
EP (1) EP0871632B1 (de)
JP (1) JP4104166B2 (de)
AT (1) ATE237621T1 (de)
AU (1) AU7494496A (de)
DE (1) DE69627533T2 (de)
DK (1) DK0871632T3 (de)
ES (1) ES2197253T3 (de)
PT (1) PT871632E (de)
TW (1) TW347383B (de)
WO (1) WO1997015579A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002517398A (ja) * 1998-06-01 2002-06-18 スミスクライン・ビーチャム・コーポレイション アモキシシリンの結晶性塩の製造方法
US6211384B1 (en) 1999-08-30 2001-04-03 Novartis Pharmaceuticals Corp. Methods for the acylation of amine compounds
AT412213B (de) * 2000-05-30 2004-11-25 Sandoz Ag Verfahren zur trocknung von amoxicillin oder amoxicillin-hältigen, oralen, festen pharmazeutischen zusammensetzungen unter verwendung eines gases mit einer definierten gasfeuchte
CN101633663B (zh) * 2009-08-28 2011-12-21 沈阳顺旺动物药业有限公司 一种青霉素类钠、钾盐的合成方法
CN102838620B (zh) * 2012-09-05 2014-07-30 河北科技大学 一种阿莫西林钠结晶的制备工艺

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1286199A (en) * 1970-03-16 1972-08-23 Beecham Group Ltd Penicillins
US3932386A (en) * 1973-06-18 1976-01-13 American Home Products Corporation Sodium 6-(L-aminocyclohexane carboxamido)penicillanic acid
GB1464026A (en) * 1974-09-25 1977-02-09 Beecham Group Ltd Preparation of beta-lactam antibiotics
GB1463563A (en) * 1974-10-10 1977-02-02 Beecham Group Ltd Pharmaceutical compositions
EP0131147B2 (de) * 1983-06-10 1996-12-04 Beecham Group p.l.c. Kristallines Amoxycillin-Salz
DE3431273A1 (de) * 1984-08-25 1986-03-06 Bayer Ag, 5090 Leverkusen Kristallines natriumsalz der d-6-((alpha)-(2-oxo-3-furfuryl-iden-amino-imidazolidin-1-yl)-carbonylamino)-thienyl-2-acetamido)-penicillansaeure, verfahren zur herstellung und seine verwendung in arzneimitteln
ES8606871A1 (es) * 1985-10-21 1986-06-01 Antibioticos Sa Un procedimiento de preparacion de amoxicilina sodica
IT1255716B (it) * 1992-10-05 1995-11-10 Procedimento per la preparazione di antibiotici beta-lattamici sterili

Also Published As

Publication number Publication date
JP4104166B2 (ja) 2008-06-18
US6103897A (en) 2000-08-15
JPH11515011A (ja) 1999-12-21
DE69627533T2 (de) 2003-12-18
DK0871632T3 (da) 2003-07-28
TW347383B (en) 1998-12-11
EP0871632B1 (de) 2003-04-16
ATE237621T1 (de) 2003-05-15
ES2197253T3 (es) 2004-01-01
AU7494496A (en) 1997-05-15
PT871632E (pt) 2003-08-29
WO1997015579A1 (en) 1997-05-01
EP0871632A1 (de) 1998-10-21

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: SANDOZ AG, BASEL, CH

8328 Change in the person/name/address of the agent

Representative=s name: KROHER, STROBEL RECHTS- UND PATENTANWAELTE, 80336

8328 Change in the person/name/address of the agent

Representative=s name: DR. SCHOEN & PARTNER, 80336 MUENCHEN