NO312679B1 - N6 heterocykliske substituerte adenosinderivater, farmasöytisk sammensetning inneholdende samme, og anvendelse avsamme for fremstilling av preparat - Google Patents
N6 heterocykliske substituerte adenosinderivater, farmasöytisk sammensetning inneholdende samme, og anvendelse avsamme for fremstilling av preparat Download PDFInfo
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- NO312679B1 NO312679B1 NO19990787A NO990787A NO312679B1 NO 312679 B1 NO312679 B1 NO 312679B1 NO 19990787 A NO19990787 A NO 19990787A NO 990787 A NO990787 A NO 990787A NO 312679 B1 NO312679 B1 NO 312679B1
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- 230000036279 refractory period Effects 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000001632 sodium acetate Substances 0.000 description 1
- 235000017281 sodium acetate Nutrition 0.000 description 1
- 235000017557 sodium bicarbonate Nutrition 0.000 description 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 1
- 239000001509 sodium citrate Substances 0.000 description 1
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 239000008117 stearic acid Substances 0.000 description 1
- 239000001384 succinic acid Substances 0.000 description 1
- 229940124530 sulfonamide Drugs 0.000 description 1
- 150000003456 sulfonamides Chemical class 0.000 description 1
- 239000006228 supernatant Substances 0.000 description 1
- 238000013268 sustained release Methods 0.000 description 1
- 239000012730 sustained-release form Substances 0.000 description 1
- 230000002889 sympathetic effect Effects 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 235000012222 talc Nutrition 0.000 description 1
- 229940124597 therapeutic agent Drugs 0.000 description 1
- 230000002110 toxicologic effect Effects 0.000 description 1
- 231100000759 toxicological effect Toxicity 0.000 description 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
- C07H19/167—Purine radicals with ribosyl as the saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NO20020759A NO20020759D0 (no) | 1996-08-27 | 2002-02-15 | N<o>6</o> heterocykliske substituerte adenosinderivater |
| NO20020758A NO322459B1 (no) | 1996-08-27 | 2002-02-15 | N6 heterocykliske substituerte adenosinderivater, farmasoytiske sammensetninger omfattende samme, og anvendelse av samme for fremstilling av medikament. |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08702234 US5789416B1 (en) | 1996-08-27 | 1996-08-27 | N6 mono heterocyclic substituted adenosine derivatives |
| PCT/US1997/014724 WO1998008855A2 (fr) | 1996-08-27 | 1997-08-20 | Derives d'adenosine a substitution heterocyclique n6 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO990787D0 NO990787D0 (no) | 1999-02-19 |
| NO990787L NO990787L (no) | 1999-02-19 |
| NO312679B1 true NO312679B1 (no) | 2002-06-17 |
Family
ID=24820367
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19990787A NO312679B1 (no) | 1996-08-27 | 1999-02-19 | N6 heterocykliske substituerte adenosinderivater, farmasöytisk sammensetning inneholdende samme, og anvendelse avsamme for fremstilling av preparat |
| NO20020759A NO20020759D0 (no) | 1996-08-27 | 2002-02-15 | N<o>6</o> heterocykliske substituerte adenosinderivater |
| NO20020758A NO322459B1 (no) | 1996-08-27 | 2002-02-15 | N6 heterocykliske substituerte adenosinderivater, farmasoytiske sammensetninger omfattende samme, og anvendelse av samme for fremstilling av medikament. |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20020759A NO20020759D0 (no) | 1996-08-27 | 2002-02-15 | N<o>6</o> heterocykliske substituerte adenosinderivater |
| NO20020758A NO322459B1 (no) | 1996-08-27 | 2002-02-15 | N6 heterocykliske substituerte adenosinderivater, farmasoytiske sammensetninger omfattende samme, og anvendelse av samme for fremstilling av medikament. |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US5789416B1 (fr) |
| EP (3) | EP0992510B1 (fr) |
| JP (1) | JP3157842B2 (fr) |
| KR (1) | KR100331775B1 (fr) |
| CN (1) | CN100363377C (fr) |
| AT (2) | ATE202361T1 (fr) |
| AU (1) | AU726597B2 (fr) |
| BR (1) | BR9711444A (fr) |
| CA (1) | CA2264155C (fr) |
| CZ (1) | CZ296855B6 (fr) |
| DE (2) | DE69719816T2 (fr) |
| DK (2) | DK0920438T3 (fr) |
| ES (2) | ES2157593T3 (fr) |
| GE (1) | GEP20012419B (fr) |
| GR (1) | GR3036332T3 (fr) |
| HK (1) | HK1020967A1 (fr) |
| HU (1) | HU226057B1 (fr) |
| IL (2) | IL128652A0 (fr) |
| NO (3) | NO312679B1 (fr) |
| NZ (3) | NZ505428A (fr) |
| PL (1) | PL187635B1 (fr) |
| PT (1) | PT920438E (fr) |
| TR (2) | TR199900377T2 (fr) |
| UA (1) | UA62936C2 (fr) |
| WO (1) | WO1998008855A2 (fr) |
Families Citing this family (61)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL127947A0 (en) | 1999-01-07 | 1999-11-30 | Can Fite Technologies Ltd | Pharmaceutical use of adenosine agonists |
| US6790839B2 (en) | 1999-01-07 | 2004-09-14 | Can-Fite Biopharma Ltd. | Pharmaceutical administration of adenosine agonists |
| US6576619B2 (en) * | 1999-05-24 | 2003-06-10 | Cv Therapeutics, Inc. | Orally active A1 adenosine receptor agonists |
| WO2000075142A2 (fr) * | 1999-05-25 | 2000-12-14 | The Penn State Research Foundation | Inhibiteurs de methyltransferase d'adn |
| EP1420021A1 (fr) * | 1999-05-25 | 2004-05-19 | The Penn State Research Foundation | Inhibiteurs de méthyltransférase d'ADN |
| US6180615B1 (en) * | 1999-06-22 | 2001-01-30 | Cv Therapeutics, Inc. | Propargyl phenyl ether A2A receptor agonists |
| US6784165B1 (en) * | 1999-11-23 | 2004-08-31 | Aderis Pharmaceuticals, Inc. | Treatment of heart rhythm disturbances with N6-substituted-5′-(N-substituted) carboxamidoadenosines |
| US6294522B1 (en) * | 1999-12-03 | 2001-09-25 | Cv Therapeutics, Inc. | N6 heterocyclic 8-modified adenosine derivatives |
| US6605597B1 (en) * | 1999-12-03 | 2003-08-12 | Cv Therapeutics, Inc. | Partial or full A1agonists-N-6 heterocyclic 5′-thio substituted adenosine derivatives |
| US6258793B1 (en) * | 1999-12-03 | 2001-07-10 | Cv Therapeutics, Inc. | N6 heterocyclic 5′ modified adenosine derivatives |
| US6576620B2 (en) * | 1999-12-03 | 2003-06-10 | Cv Therapeutics, Inc. | Method of identifying partial adenosine A1 receptor agonists |
| ES2215146T3 (es) * | 2000-09-08 | 2004-10-01 | Cv Therapeutics, Inc. | Utilizacion de ribosidos purina como antiarritmicos. |
| GB0100623D0 (en) | 2001-01-10 | 2001-02-21 | Vernalis Res Ltd | Chemical compounds IV |
| EP1241176A1 (fr) * | 2001-03-16 | 2002-09-18 | Pfizer Products Inc. | Dérivés de purine pour le traitement de l'ischémie |
| US20050227933A1 (en) * | 2001-11-29 | 2005-10-13 | Benkovic Stephen J | Treatment of bacterial induced diseases using DNA methyl transferase inhibitors |
| WO2003059916A2 (fr) * | 2002-01-10 | 2003-07-24 | The Pennsylvania State Research Foundation | Procedes de preparation d'alkyl diarylborinates et d'acides diarylboroniques complexes |
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| KR20050097971A (ko) * | 2003-02-03 | 2005-10-10 | 씨브이 쎄러퓨틱스, 인코포레이티드 | Ａ₁아데노신 수용체의 부분 및 전 작용제 |
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| EP1633756B1 (fr) | 2003-04-09 | 2008-12-24 | Biogen Idec MA Inc. | Antagonistes de recepteur d'adenosine a2a |
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| EA011826B1 (ru) * | 2004-05-26 | 2009-06-30 | Инотек Фармасьютикалз Корпорейшн | Пуриновые производные в качестве агонистов аденозиновых арецепторов и способы их применения |
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| CN100451010C (zh) * | 2004-12-21 | 2009-01-14 | 厦门大学 | 一种合成(r)-3-氨基四氢呋喃的方法 |
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| CN100344768C (zh) * | 2005-11-24 | 2007-10-24 | 东华大学 | 一种3－(s)－氨基四氢呋喃的酶法合成方法 |
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| WO2010008582A2 (fr) | 2008-07-18 | 2010-01-21 | Rxi Pharmaceuticals Corporation | Système permettant d'administrer un médicament aux cellules phagocytaires |
| AU2009293658A1 (en) | 2008-09-22 | 2010-03-25 | James Cardia | Reduced size self-delivering RNAi compounds |
| WO2010059226A2 (fr) | 2008-11-19 | 2010-05-27 | Rxi Pharmaceuticals Corporation | Inhibition de map4k4 via arni |
| WO2010078536A1 (fr) | 2009-01-05 | 2010-07-08 | Rxi Pharmaceuticals Corporation | Inhibition de pcsk9 par arni |
| US9745574B2 (en) | 2009-02-04 | 2017-08-29 | Rxi Pharmaceuticals Corporation | RNA duplexes with single stranded phosphorothioate nucleotide regions for additional functionality |
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| CN106074591B (zh) | 2010-03-24 | 2020-01-14 | 菲奥医药公司 | 眼部症候中的rna干扰 |
| WO2011119969A1 (fr) | 2010-03-26 | 2011-09-29 | Inotek Pharmaceuticals Corporation | Procédé de réduction de la pression intraoculaire chez l'homme à l'aide de n6-cyclopentyladénosine (cpa), de dérivés ou de promédicaments de cpa |
| DE102011005232A1 (de) | 2011-03-08 | 2012-09-13 | AristoCon GmbH & Co. KG | Adenosin und seine Derivate zur Verwendung in der Schmerztherapie |
| DK2807178T3 (en) | 2012-01-26 | 2017-09-04 | Inotek Pharmaceuticals Corp | Anhydrous polymorphs of (2R, 3S, 4R, 5R) -5- (6- (cyclopentylamino) -9H-purin-9-yl) -3,4-dihydroxytetrahydrofuran-2-yl) methyl nitrate and processes for their preparation |
| SG11201506882YA (en) | 2013-03-15 | 2015-09-29 | Inotek Pharmaceuticals Corp | Ophthalmic formulations |
| US10934550B2 (en) | 2013-12-02 | 2021-03-02 | Phio Pharmaceuticals Corp. | Immunotherapy of cancer |
| CA2932753A1 (fr) | 2013-12-04 | 2015-06-11 | Rxi Pharmaceuticals Corporation | Methodes de traitement de cicatrisation a l'aide d'oligonucleotides chimiquement modifies |
| US11279934B2 (en) | 2014-04-28 | 2022-03-22 | Phio Pharmaceuticals Corp. | Methods for treating cancer using nucleic acids targeting MDM2 or MYCN |
| US20170051290A1 (en) | 2014-05-01 | 2017-02-23 | Rxi Pharmaceuticals Corporation | Methods for treatment of disorders in the front of the eye utilizing nucleic acid molecules |
| EP3188799B1 (fr) | 2014-09-05 | 2022-07-06 | Phio Pharmaceuticals Corp. | Méthodes de traitement de troubles cutanés et du vieillissement à l'aide d'acides nucléiques ciblant tyr ou mmp1 |
| JP6983752B2 (ja) | 2015-07-06 | 2021-12-17 | フィオ ファーマシューティカルズ コーポレーションPhio Pharmaceuticals Corp. | スーパーオキシドディスムターゼ１（ｓｏｄ１）を標的とする核酸分子 |
| WO2017007825A1 (fr) | 2015-07-06 | 2017-01-12 | Rxi Pharmaceuticals Corporation | Procédés pour le traitement de troubles neurologiques à l'aide d'une petite molécule synergique et approche thérapeutique utilisant des acides nucléiques |
| JP2018531037A (ja) | 2015-10-19 | 2018-10-25 | アールエックスアイ ファーマシューティカルズ コーポレーション | 長い非コードｒｎａを標的とする減少したサイズの自己送達型核酸化合物 |
| CN105218490B (zh) * | 2015-11-10 | 2017-05-03 | 山东川成医药股份有限公司 | 一种（r）‑3‑氨基四氢呋喃的制备方法 |
| US20230002766A1 (en) | 2019-11-08 | 2023-01-05 | Phio Pharmaceuticals Corp. | Chemically modified oligonucleotides targeting bromodomain containing protein 4 (brd4) for immunotherapy |
| EP4085136A1 (fr) | 2019-12-31 | 2022-11-09 | Phio Pharmaceuticals Corp. | Oligonucléotides chimiquement modifiés présentant une administration systémique améliorée |
| WO2023015264A1 (fr) | 2021-08-04 | 2023-02-09 | Phio Pharmaceuticals Corp. | Immunothérapie anticancéreuse utilisant des cellules tueuses naturelles traitées avec des oligonucléotides chimiquement modifiés |
| EP4381070A2 (fr) | 2021-08-04 | 2024-06-12 | Phio Pharmaceuticals Corp. | Oligonucléotides chimiquement modifiés |
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| DE2460929A1 (de) * | 1974-12-21 | 1976-06-24 | Boehringer Sohn Ingelheim | Neue xanthinderivate, verfahren zu ihrer herstellung und ihre anwendung |
| US4364922A (en) * | 1980-10-14 | 1982-12-21 | University Of Virginia Alumni Patents Foundation | Adenosine antagonists in the treatment and diagnosis of A-V node conduction disturbances |
| JPS57171998A (en) * | 1981-04-15 | 1982-10-22 | Fujisawa Pharmaceut Co Ltd | Adenosine derivative and its salt, preparation thereof and medicinal composition containing the same |
| DE3138397A1 (de) * | 1981-09-26 | 1983-04-07 | Hoechst Ag, 6230 Frankfurt | "arzneimittel, darin enthaltene vicinale dihydroxyalkylxanthine und herstellungsverfahren fuer diese xanthinverbindungen" |
| AU577743B2 (en) * | 1984-10-26 | 1988-09-29 | Warner-Lambert Company | N6-benzopyrano and benzothiopyrano adenosines |
| AU8274187A (en) * | 1986-10-31 | 1988-05-25 | Warner-Lambert Company | Heteroaromatic derivatives of adenosine |
| US4954504A (en) * | 1986-11-14 | 1990-09-04 | Ciba-Geigy Corporation | N9 -cyclopentyl-substituted adenine derivatives having adenosine-2 receptor stimulating activity |
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| US4980379A (en) * | 1988-06-30 | 1990-12-25 | The University Of Virginia | Use of adenosine antagonists in the treatment of bradyarrhythmias and hemodynamic depression associated with cardiopulmonary resucitation and/or cardiovascular collapse |
| IE882585L (en) * | 1988-08-25 | 1990-02-25 | Prendergast Patrick T | Viral treatment system |
| DE8817122U1 (de) * | 1988-12-22 | 1993-02-04 | Boehringer Ingelheim Kg, 55218 Ingelheim | Neue Xanthinderivate mit Adenosinantogenistischer Wirkung |
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| DE4019892A1 (de) * | 1990-06-22 | 1992-01-02 | Boehringer Ingelheim Kg | Neue xanthinderivate |
| US5432164A (en) * | 1991-10-24 | 1995-07-11 | Novo Nordisk A/S | C2,N6 -disubstituted adenosine derivatives |
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-
1996
- 1996-08-27 US US08702234 patent/US5789416B1/en not_active Expired - Lifetime
-
1997
- 1997-08-20 DE DE69719816T patent/DE69719816T2/de not_active Expired - Lifetime
- 1997-08-20 ES ES97938502T patent/ES2157593T3/es not_active Expired - Lifetime
- 1997-08-20 KR KR1019997001563A patent/KR100331775B1/ko not_active IP Right Cessation
- 1997-08-20 IL IL12865297A patent/IL128652A0/xx active IP Right Grant
- 1997-08-20 CA CA002264155A patent/CA2264155C/fr not_active Expired - Fee Related
- 1997-08-20 DK DK97938502T patent/DK0920438T3/da active
- 1997-08-20 UA UA99021148A patent/UA62936C2/uk unknown
- 1997-08-20 AU AU40809/97A patent/AU726597B2/en not_active Ceased
- 1997-08-20 CZ CZ0061499A patent/CZ296855B6/cs not_active IP Right Cessation
- 1997-08-20 NZ NZ505428A patent/NZ505428A/en unknown
- 1997-08-20 PL PL97331853A patent/PL187635B1/pl not_active IP Right Cessation
- 1997-08-20 WO PCT/US1997/014724 patent/WO1998008855A2/fr active IP Right Grant
- 1997-08-20 DE DE69705312T patent/DE69705312T2/de not_active Expired - Lifetime
- 1997-08-20 TR TR1999/00377T patent/TR199900377T2/xx unknown
- 1997-08-20 JP JP51173698A patent/JP3157842B2/ja not_active Expired - Fee Related
- 1997-08-20 DK DK99119389T patent/DK0992510T3/da active
- 1997-08-20 BR BR9711444-8A patent/BR9711444A/pt active Search and Examination
- 1997-08-20 AT AT97938502T patent/ATE202361T1/de active
- 1997-08-20 AT AT99119389T patent/ATE234323T1/de active
- 1997-08-20 NZ NZ334095A patent/NZ334095A/xx not_active IP Right Cessation
- 1997-08-20 EP EP99119389A patent/EP0992510B1/fr not_active Expired - Lifetime
- 1997-08-20 GE GEAP19974728A patent/GEP20012419B/en unknown
- 1997-08-20 ES ES99119389T patent/ES2189330T3/es not_active Expired - Lifetime
- 1997-08-20 TR TR2002/02287T patent/TR200202287T2/xx unknown
- 1997-08-20 EP EP97938502A patent/EP0920438B1/fr not_active Expired - Lifetime
- 1997-08-20 CN CNB971991790A patent/CN100363377C/zh not_active Expired - Fee Related
- 1997-08-20 HU HU0001640A patent/HU226057B1/hu not_active IP Right Cessation
- 1997-08-20 PT PT97938502T patent/PT920438E/pt unknown
- 1997-08-20 EP EP00123879A patent/EP1081155A3/fr not_active Withdrawn
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1999
- 1999-02-19 NO NO19990787A patent/NO312679B1/no not_active IP Right Cessation
- 1999-02-22 IL IL128652A patent/IL128652A/en not_active IP Right Cessation
- 1999-12-30 HK HK99106191A patent/HK1020967A1/xx not_active IP Right Cessation
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2001
- 2001-06-08 NZ NZ512242A patent/NZ512242A/xx not_active IP Right Cessation
- 2001-08-06 GR GR20010401184T patent/GR3036332T3/el unknown
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2002
- 2002-02-15 NO NO20020759A patent/NO20020759D0/no not_active Application Discontinuation
- 2002-02-15 NO NO20020758A patent/NO322459B1/no not_active IP Right Cessation
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