NO304952B1 - Plasmider for anvendelse ved fremstilling av en plasminogenaktivator og anvendelse av plasmidet - Google Patents
Plasmider for anvendelse ved fremstilling av en plasminogenaktivator og anvendelse av plasmidet Download PDFInfo
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- NO304952B1 NO304952B1 NO902720A NO902720A NO304952B1 NO 304952 B1 NO304952 B1 NO 304952B1 NO 902720 A NO902720 A NO 902720A NO 902720 A NO902720 A NO 902720A NO 304952 B1 NO304952 B1 NO 304952B1
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- 230000000977 initiatory effect Effects 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
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- 229910052943 magnesium sulfate Inorganic materials 0.000 description 1
- 235000019341 magnesium sulphate Nutrition 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 108020004999 messenger RNA Proteins 0.000 description 1
- DEQXHPXOGUSHDX-UHFFFAOYSA-N methylaminomethanetriol;hydrochloride Chemical compound Cl.CNC(O)(O)O DEQXHPXOGUSHDX-UHFFFAOYSA-N 0.000 description 1
- 238000010369 molecular cloning Methods 0.000 description 1
- 239000000178 monomer Substances 0.000 description 1
- 208000010125 myocardial infarction Diseases 0.000 description 1
- YPZRWBKMTBYPTK-UHFFFAOYSA-N oxidized gamma-L-glutamyl-L-cysteinylglycine Natural products OC(=O)C(N)CCC(=O)NC(C(=O)NCC(O)=O)CSSCC(C(=O)NCC(O)=O)NC(=O)CCC(N)C(O)=O YPZRWBKMTBYPTK-UHFFFAOYSA-N 0.000 description 1
- 239000008188 pellet Substances 0.000 description 1
- 239000012071 phase Substances 0.000 description 1
- 239000008363 phosphate buffer Substances 0.000 description 1
- 230000000865 phosphorylative effect Effects 0.000 description 1
- 229920002401 polyacrylamide Polymers 0.000 description 1
- 238000002264 polyacrylamide gel electrophoresis Methods 0.000 description 1
- 229920001184 polypeptide Polymers 0.000 description 1
- 235000015277 pork Nutrition 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 235000019260 propionic acid Nutrition 0.000 description 1
- 108020001775 protein parts Proteins 0.000 description 1
- IUVKMZGDUIUOCP-BTNSXGMBSA-N quinbolone Chemical compound O([C@H]1CC[C@H]2[C@H]3[C@@H]([C@]4(C=CC(=O)C=C4CC3)C)CC[C@@]21C)C1=CCCC1 IUVKMZGDUIUOCP-BTNSXGMBSA-N 0.000 description 1
- 239000011541 reaction mixture Substances 0.000 description 1
- 238000002271 resection Methods 0.000 description 1
- 108091008146 restriction endonucleases Proteins 0.000 description 1
- 238000004007 reversed phase HPLC Methods 0.000 description 1
- 239000012266 salt solution Substances 0.000 description 1
- 239000000523 sample Substances 0.000 description 1
- 229960002055 saruplase Drugs 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 238000010532 solid phase synthesis reaction Methods 0.000 description 1
- 235000011069 sorbitan monooleate Nutrition 0.000 description 1
- 239000001593 sorbitan monooleate Substances 0.000 description 1
- 229940035049 sorbitan monooleate Drugs 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6456—Plasminogen activators
- C12N9/6462—Plasminogen activators u-Plasminogen activator (3.4.21.73), i.e. urokinase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/67—General methods for enhancing the expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21073—Serine endopeptidases (3.4.21) u-Plasminogen activator (3.4.21.73), i.e. urokinase
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Saccharide Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3923866 | 1989-07-19 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO902720D0 NO902720D0 (no) | 1990-06-19 |
| NO902720L NO902720L (no) | 1991-01-21 |
| NO304952B1 true NO304952B1 (no) | 1999-03-08 |
Family
ID=6385369
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO902720A NO304952B1 (no) | 1989-07-19 | 1990-06-19 | Plasmider for anvendelse ved fremstilling av en plasminogenaktivator og anvendelse av plasmidet |
Country Status (30)
| Country | Link |
|---|---|
| US (1) | US5637503A (ko) |
| EP (1) | EP0408945B1 (ko) |
| JP (1) | JP3236284B2 (ko) |
| KR (1) | KR0167761B1 (ko) |
| AT (1) | ATE131534T1 (ko) |
| AU (1) | AU631662B2 (ko) |
| CA (1) | CA2020656C (ko) |
| DD (1) | DD298426A5 (ko) |
| DE (2) | DE4020438A1 (ko) |
| DK (1) | DK0408945T3 (ko) |
| ES (1) | ES2083399T3 (ko) |
| FI (1) | FI102386B (ko) |
| GR (1) | GR3019294T3 (ko) |
| HK (1) | HK1005193A1 (ko) |
| HR (1) | HRP920596B1 (ko) |
| HU (1) | HU214243B (ko) |
| IE (1) | IE901849A1 (ko) |
| IL (1) | IL94529A (ko) |
| LT (1) | LT3611B (ko) |
| LV (1) | LV10120B (ko) |
| MT (1) | MTP1063B (ko) |
| NO (1) | NO304952B1 (ko) |
| NZ (1) | NZ234542A (ko) |
| PL (1) | PL166199B1 (ko) |
| PT (1) | PT94776B (ko) |
| RU (1) | RU2073720C1 (ko) |
| SI (1) | SI9011347B (ko) |
| SK (1) | SK280028B6 (ko) |
| YU (1) | YU48371B (ko) |
| ZA (1) | ZA904006B (ko) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2067226A1 (ko) * | 1969-11-27 | 1971-08-20 | Cefilac | |
| DE4101736A1 (de) * | 1991-01-22 | 1992-07-23 | Gruenenthal Gmbh | Neue als plasminogenaktivatoren einsetzbare polypeptide, dafuer codierende plasmide und verfahren zu deren herstellung und deren verwendung |
| DE4440892A1 (de) * | 1994-11-17 | 1996-05-23 | Gruenenthal Gmbh | Proteine mit fibrinolytischen und gerinnungshemmenden Eigenschaften |
| DE4442665A1 (de) * | 1994-11-30 | 1996-06-05 | Gruenenthal Gmbh | Chimäre Proteine mit fibrinolytischen und thrombinhemmenden Eigenschaften |
| KR100467034B1 (ko) * | 1996-12-27 | 2006-04-07 | 주식회사 엘지생활건강 | 압축성형타입오일케익화장료및그의제조방법 |
| KR100372233B1 (ko) * | 1997-03-12 | 2003-06-11 | 주식회사 코리아나화장품 | 미백 파우더, 그의 제조방법 및 그를 함유하는 메이크업 미백 화장료 |
| KR100341638B1 (ko) * | 2000-03-17 | 2002-06-22 | 유상옥,송운한 | 기능성 표면처리 분체의 제조 방법 및 이를 함유하는메이크업 화장료 조성물 |
| JP4124639B2 (ja) * | 2002-12-17 | 2008-07-23 | 株式会社日本触媒 | 大腸菌を用いたｓ−ヒドロキシニトリルリアーゼの製造方法 |
| US7906276B2 (en) * | 2004-06-30 | 2011-03-15 | Kimberly-Clark Worldwide, Inc. | Enzymatic detection techniques |
| UA100692C2 (ru) | 2007-05-02 | 2013-01-25 | Мериал Лимитед | Днк-плазмиды, имеющие повышенную экспрессию и стабильность |
| RU2553533C2 (ru) * | 2013-10-23 | 2015-06-20 | Общество с ограниченной ответственностью "Международный биотехнологический центр "Генериум" ("МБЦ "Генериум") | Способ выделения и очистки рекомбинантной человеческой проурокиназы м5 |
| CN104555732A (zh) * | 2015-01-18 | 2015-04-29 | 河南省中原起重机械总厂 | 一种多功能门式起重机 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4370417A (en) * | 1980-04-03 | 1983-01-25 | Abbott Laboratories | Recombinant deoxyribonucleic acid which codes for plasminogen activator |
| US4558010A (en) * | 1980-04-03 | 1985-12-10 | Abbott Laboratories | Recombinant deoxyribonucleic acid which codes for plasminogen activator and method of making plasminogen activator protein therefrom |
| FI88932C (fi) * | 1982-04-15 | 1993-07-26 | Genentech Inc | Framstaellning av funktionellt maenskligt urokinasprotein |
| US4710464A (en) * | 1984-09-27 | 1987-12-01 | Eli Lilly And Company | Transcription terminators |
| DE3680838D1 (de) * | 1985-01-25 | 1991-09-19 | Sagami Chem Res | Stabilisierte menschliche prourokinase. |
| FR2594845B1 (fr) * | 1986-02-21 | 1989-12-01 | Genetica | Preparation par voie microbiologique de l'activateur tissulaire humain du plasminogene (t-pa) et conversion de l'enzyme ainsi obtenue en sa forme active |
| FI100106B (fi) * | 1986-12-05 | 1997-09-30 | Novartis Ag | Menetelmä plasminogeenin yksisäikeisen yhdistelmäaktivaattorin valmist amiseksi |
| HU208712B (en) * | 1987-08-10 | 1993-12-28 | Lepetit Spa | Method for preparing single or double strained glycolised human urokinase and pharmaceutical composition comprising same |
| EP0372005A4 (en) * | 1987-10-30 | 1990-06-26 | Oncogen | EXPRESSION SYSTEMS FOR THE PREPARATION OF POLYPEPTIDES IN PROKARYOTIC CELLS. |
-
1990
- 1990-05-22 IE IE184990A patent/IE901849A1/en not_active Application Discontinuation
- 1990-05-23 ZA ZA904006A patent/ZA904006B/xx unknown
- 1990-05-28 IL IL94529A patent/IL94529A/xx not_active IP Right Cessation
- 1990-06-19 NO NO902720A patent/NO304952B1/no not_active IP Right Cessation
- 1990-06-20 SK SK3067-90A patent/SK280028B6/sk unknown
- 1990-06-25 HU HU903970A patent/HU214243B/hu not_active IP Right Cessation
- 1990-06-27 DE DE4020438A patent/DE4020438A1/de not_active Withdrawn
- 1990-06-28 MT MT1063A patent/MTP1063B/xx unknown
- 1990-06-29 AT AT90112400T patent/ATE131534T1/de not_active IP Right Cessation
- 1990-06-29 DE DE59009961T patent/DE59009961D1/de not_active Expired - Fee Related
- 1990-06-29 DK DK90112400.8T patent/DK0408945T3/da active
- 1990-06-29 ES ES90112400T patent/ES2083399T3/es not_active Expired - Lifetime
- 1990-06-29 EP EP90112400A patent/EP0408945B1/de not_active Expired - Lifetime
- 1990-07-06 CA CA002020656A patent/CA2020656C/en not_active Expired - Fee Related
- 1990-07-09 AU AU58832/90A patent/AU631662B2/en not_active Ceased
- 1990-07-11 YU YU134790A patent/YU48371B/sh unknown
- 1990-07-11 SI SI9011347A patent/SI9011347B/sl unknown
- 1990-07-12 US US07/551,907 patent/US5637503A/en not_active Expired - Fee Related
- 1990-07-17 PL PL90286087A patent/PL166199B1/pl unknown
- 1990-07-17 NZ NZ234542A patent/NZ234542A/xx unknown
- 1990-07-18 DD DD90342894A patent/DD298426A5/de not_active IP Right Cessation
- 1990-07-18 KR KR1019900010860A patent/KR0167761B1/ko not_active IP Right Cessation
- 1990-07-18 JP JP18816990A patent/JP3236284B2/ja not_active Expired - Fee Related
- 1990-07-18 RU SU4831114/13A patent/RU2073720C1/ru not_active IP Right Cessation
- 1990-07-18 FI FI903640A patent/FI102386B/fi not_active IP Right Cessation
- 1990-07-19 PT PT94776A patent/PT94776B/pt not_active IP Right Cessation
-
1992
- 1992-09-29 HR HRP-1347/90A patent/HRP920596B1/xx not_active IP Right Cessation
- 1992-11-13 LV LVP-92-204A patent/LV10120B/lv unknown
-
1993
- 1993-07-12 LT LTIP776A patent/LT3611B/lt not_active IP Right Cessation
-
1996
- 1996-03-13 GR GR960400698T patent/GR3019294T3/el unknown
-
1998
- 1998-05-19 HK HK98104295A patent/HK1005193A1/xx not_active IP Right Cessation
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Legal Events
| Date | Code | Title | Description |
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| MM1K | Lapsed by not paying the annual fees |