UA100692C2 - Днк-плазмиды, имеющие повышенную экспрессию и стабильность - Google Patents

Днк-плазмиды, имеющие повышенную экспрессию и стабильность

Info

Publication number
UA100692C2
UA100692C2 UAA200912372A UAA200912372A UA100692C2 UA 100692 C2 UA100692 C2 UA 100692C2 UA A200912372 A UAA200912372 A UA A200912372A UA A200912372 A UAA200912372 A UA A200912372A UA 100692 C2 UA100692 C2 UA 100692C2
Authority
UA
Ukraine
Prior art keywords
dna
stability
increased expression
plasmids
appealing
Prior art date
Application number
UAA200912372A
Other languages
English (en)
Ukrainian (uk)
Inventor
Жан-Кристоф Одоне
Original Assignee
Мериал Лимитед
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Мериал Лимитед filed Critical Мериал Лимитед
Publication of UA100692C2 publication Critical patent/UA100692C2/ru

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C12N15/68—Stabilisation of the vector
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression

Abstract

Изобретение относится к ДНК-плазмиде с повышенной экспрессией экзогенных полипептидов, таких как антиген, эпитоп, иммуноген, пептид или полипептид, который представляет интерес, и стабильностью, к способам, пригодным для ДНК-вакцинации.
UAA200912372A 2007-05-02 2007-05-02 Днк-плазмиды, имеющие повышенную экспрессию и стабильность UA100692C2 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2007/010547 WO2008136790A1 (en) 2007-05-02 2007-05-02 Dna plasmids having improved expression and stability

Publications (1)

Publication Number Publication Date
UA100692C2 true UA100692C2 (ru) 2013-01-25

Family

ID=38728755

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200912372A UA100692C2 (ru) 2007-05-02 2007-05-02 Днк-плазмиды, имеющие повышенную экспрессию и стабильность

Country Status (14)

Country Link
EP (1) EP2147105B1 (ru)
JP (1) JP2010525812A (ru)
KR (1) KR101445903B1 (ru)
CN (1) CN102016045A (ru)
AU (1) AU2007352618B2 (ru)
BR (1) BRPI0721630A2 (ru)
CA (1) CA2684923C (ru)
DK (1) DK2147105T3 (ru)
HR (1) HRP20130643T1 (ru)
IN (1) IN2009DN07240A (ru)
MX (1) MX2009011851A (ru)
SI (1) SI2147105T1 (ru)
UA (1) UA100692C2 (ru)
WO (1) WO2008136790A1 (ru)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9045759B2 (en) 2009-01-21 2015-06-02 James Arthur Williams DNA plasmids with improved copy number
CN104726505A (zh) * 2015-03-31 2015-06-24 上海交通大学 一种利用基因工程蓝藻生产三碳化合物的方法

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CA2684923A1 (en) 2008-11-13
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SI2147105T1 (sl) 2013-08-30
BRPI0721630A2 (pt) 2013-10-15
IN2009DN07240A (ru) 2015-07-24
CA2684923C (en) 2015-01-06
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WO2008136790A1 (en) 2008-11-13
CN102016045A (zh) 2011-04-13

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