NO301168B1 - Fremgangsmåte for fremstilling av et konjugat av et antistoff rettet mot antigen - Google Patents
Fremgangsmåte for fremstilling av et konjugat av et antistoff rettet mot antigen Download PDFInfo
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- NO301168B1 NO301168B1 NO901986A NO901986A NO301168B1 NO 301168 B1 NO301168 B1 NO 301168B1 NO 901986 A NO901986 A NO 901986A NO 901986 A NO901986 A NO 901986A NO 301168 B1 NO301168 B1 NO 301168B1
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- tnf
- cells
- antibody
- antigen
- tumor
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Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
- A61K47/6851—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
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- Immunology (AREA)
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- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Ophthalmology & Optometry (AREA)
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- Cell Biology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Materials For Medical Uses (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
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US34823789A | 1989-05-05 | 1989-05-05 |
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NO901986A NO301168B1 (no) | 1989-05-05 | 1990-05-04 | Fremgangsmåte for fremstilling av et konjugat av et antistoff rettet mot antigen |
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EP (1) | EP0396387B1 (ko) |
JP (1) | JP3589459B2 (ko) |
KR (1) | KR0181294B1 (ko) |
CN (1) | CN1072505C (ko) |
AT (1) | ATE98873T1 (ko) |
AU (1) | AU645747B2 (ko) |
CA (1) | CA2015060C (ko) |
DE (1) | DE69005352T2 (ko) |
DK (1) | DK0396387T3 (ko) |
ES (1) | ES2060947T3 (ko) |
FI (1) | FI100092B (ko) |
HK (1) | HK1006678A1 (ko) |
IE (1) | IE63847B1 (ko) |
IL (1) | IL94167A (ko) |
NO (1) | NO301168B1 (ko) |
NZ (1) | NZ233413A (ko) |
PT (1) | PT93966B (ko) |
SA (1) | SA90110099B1 (ko) |
ZA (1) | ZA902949B (ko) |
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1990
- 1990-04-19 IE IE140590A patent/IE63847B1/en not_active IP Right Cessation
- 1990-04-19 ZA ZA902949A patent/ZA902949B/xx unknown
- 1990-04-20 CA CA002015060A patent/CA2015060C/en not_active Expired - Lifetime
- 1990-04-23 IL IL9416790A patent/IL94167A/xx not_active IP Right Cessation
- 1990-04-23 NZ NZ233413A patent/NZ233413A/en unknown
- 1990-04-23 AU AU53795/90A patent/AU645747B2/en not_active Ceased
- 1990-05-01 EP EP90304734A patent/EP0396387B1/en not_active Expired - Lifetime
- 1990-05-01 DE DE90304734T patent/DE69005352T2/de not_active Expired - Fee Related
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- 1990-05-01 AT AT90304734T patent/ATE98873T1/de not_active IP Right Cessation
- 1990-05-01 ES ES90304734T patent/ES2060947T3/es not_active Expired - Lifetime
- 1990-05-01 DK DK90304734.8T patent/DK0396387T3/da active
- 1990-05-04 FI FI902245A patent/FI100092B/fi active IP Right Grant
- 1990-05-04 PT PT93966A patent/PT93966B/pt not_active IP Right Cessation
- 1990-05-04 KR KR1019900006320A patent/KR0181294B1/ko not_active IP Right Cessation
- 1990-05-04 NO NO901986A patent/NO301168B1/no not_active IP Right Cessation
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IL94167A0 (en) | 1991-01-31 |
DK0396387T3 (da) | 1994-02-14 |
IE901405L (en) | 1990-11-05 |
FI902245A0 (fi) | 1990-05-04 |
ES2060947T3 (es) | 1994-12-01 |
KR0181294B1 (ko) | 1999-03-20 |
KR900017612A (ko) | 1990-12-19 |
NZ233413A (en) | 1992-05-26 |
CN1072505C (zh) | 2001-10-10 |
CN1047035A (zh) | 1990-11-21 |
JPH02306923A (ja) | 1990-12-20 |
SA90110099B1 (ar) | 2004-02-15 |
CA2015060C (en) | 2008-03-18 |
EP0396387A2 (en) | 1990-11-07 |
EP0396387B1 (en) | 1993-12-22 |
NO901986D0 (no) | 1990-05-04 |
CA2015060A1 (en) | 1990-11-05 |
IE63847B1 (en) | 1995-06-14 |
ZA902949B (en) | 1992-02-26 |
HK1006678A1 (en) | 1999-03-12 |
FI100092B (fi) | 1997-09-30 |
PT93966A (pt) | 1991-02-08 |
PT93966B (pt) | 1996-12-31 |
ATE98873T1 (de) | 1994-01-15 |
IL94167A (en) | 1997-02-18 |
AU5379590A (en) | 1990-11-08 |
JP3589459B2 (ja) | 2004-11-17 |
DE69005352T2 (de) | 1994-04-14 |
NO901986L (no) | 1990-11-06 |
EP0396387A3 (en) | 1991-04-03 |
DE69005352D1 (de) | 1994-02-03 |
AU645747B2 (en) | 1994-01-27 |
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