NO2019037I1 - pegvaliase - Google Patents

pegvaliase

Info

Publication number
NO2019037I1
NO2019037I1 NO2019037C NO2019037C NO2019037I1 NO 2019037 I1 NO2019037 I1 NO 2019037I1 NO 2019037 C NO2019037 C NO 2019037C NO 2019037 C NO2019037 C NO 2019037C NO 2019037 I1 NO2019037 I1 NO 2019037I1
Authority
NO
Norway
Prior art keywords
pegvaliase
Prior art date
Application number
NO2019037C
Other languages
English (en)
Original Assignee
Biomarin Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39868905&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO2019037(I1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Biomarin Pharm Inc filed Critical Biomarin Pharm Inc
Publication of NO2019037I1 publication Critical patent/NO2019037I1/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/51—Lyases (4)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Obesity (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
NO2019037C 2007-05-25 2019-10-16 pegvaliase NO2019037I1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/807,227 US7534595B2 (en) 2006-06-12 2007-05-25 Compositions of prokaryotic phenylalanine ammonia-lyase and methods of using compositions thereof
PCT/US2008/006661 WO2008153776A1 (en) 2007-05-25 2008-05-23 Compositions of prokaryotic phenylalanine ammonia-lyase and methods of using said compositions

Publications (1)

Publication Number Publication Date
NO2019037I1 true NO2019037I1 (no) 2019-10-16

Family

ID=39868905

Family Applications (1)

Application Number Title Priority Date Filing Date
NO2019037C NO2019037I1 (no) 2007-05-25 2019-10-16 pegvaliase

Country Status (30)

Country Link
US (1) US7534595B2 (no)
EP (2) EP2152868B1 (no)
JP (1) JP5670183B2 (no)
KR (2) KR20150038753A (no)
CN (1) CN101842482B (no)
AR (2) AR066716A1 (no)
AU (1) AU2008263190B2 (no)
BR (1) BRPI0811267B8 (no)
CA (1) CA2687450C (no)
CL (1) CL2008001497A1 (no)
CY (2) CY1116894T1 (no)
DK (1) DK2152868T3 (no)
EA (1) EA018443B1 (no)
ES (1) ES2551315T3 (no)
HK (1) HK1135141A1 (no)
HR (1) HRP20151268T1 (no)
HU (2) HUE025784T2 (no)
IL (1) IL202132A (no)
LT (1) LTC2152868I2 (no)
LU (1) LUC00133I2 (no)
MX (1) MX2009012453A (no)
MY (1) MY151413A (no)
NL (1) NL301011I2 (no)
NO (1) NO2019037I1 (no)
PE (1) PE20090315A1 (no)
PL (1) PL2152868T3 (no)
PT (1) PT2152868E (no)
SI (1) SI2152868T1 (no)
TW (1) TWI418633B (no)
WO (1) WO2008153776A1 (no)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
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US7531341B1 (en) 2006-06-12 2009-05-12 Biomarin Pharmaceutical Inc. Compositions of prokaryotic phenylalanine ammonia-lyase and methods of using compositions thereof
US7534595B2 (en) * 2006-06-12 2009-05-19 Biomarin Pharmaceutical Inc. Compositions of prokaryotic phenylalanine ammonia-lyase and methods of using compositions thereof
US7537923B2 (en) 2007-08-17 2009-05-26 Biomarin Pharmaceutical Inc. Compositions of prokaryotic phenylalanine ammonia-lyase and methods of treating cancer using compositions thereof
US20110201022A1 (en) 2008-07-30 2011-08-18 Biomarin Pharmaceutical Inc. Assays for detection of phenylalanine ammonia-lyase and antibodies to phenylalanine ammonia-lyase
ES2582459T3 (es) * 2010-02-04 2016-09-13 Biomarin Pharmaceutical Inc. Composiciones de variantes de fenilalanina amoníaco-liasa de procariotas y métodos de uso de sus composiciones
US20150246083A1 (en) * 2012-07-27 2015-09-03 University Of North Texas Genetically modified probiotic for the treatment of phenylketonuria (pku) disease
HUE043549T2 (hu) 2013-04-18 2019-08-28 Codexis Inc Átszerkesztett fenilalanin-ammónia-liáz polipeptidek
CA2930665A1 (en) 2013-11-18 2015-05-21 Rubius Therapeutics, Inc. Synthetic membrane-receiver complexes
US10869898B2 (en) 2014-04-01 2020-12-22 Rubius Therapeutics, Inc. Methods and compositions for immunomodulation
WO2015161019A1 (en) * 2014-04-16 2015-10-22 Codexis, Inc. Engineered tyrosine ammonia lyase
LT3237621T (lt) 2014-12-22 2023-09-25 Codexis, Inc. Žmogaus alfa-galaktozidazės variantai
TW202330904A (zh) 2015-08-04 2023-08-01 美商再生元醫藥公司 補充牛磺酸之細胞培養基及用法
US11584780B2 (en) 2016-07-26 2023-02-21 Biomarin Pharmaceutical Inc. Adeno-associated virus capsid proteins
WO2018043546A1 (ja) * 2016-08-30 2018-03-08 三菱ケミカル株式会社 変異型酵素の製造方法及び変異型アルコールアシルトランスフェラーゼ
CN106497905A (zh) * 2016-12-14 2017-03-15 江南大学 一株鱼腥藻来源的苯丙氨酸脱氨酶的突变体
SG11201906880VA (en) * 2017-02-13 2019-08-27 Codexis Inc Engineered phenylalanine ammonia lyase polypeptides
CN107653275A (zh) * 2017-10-30 2018-02-02 安徽工程大学 D‑苯丙氨酸的制备方法
CN108004225B (zh) * 2017-12-19 2020-05-08 江南大学 一种成团泛菌来源的苯丙氨酸氨基变位酶的突变体
KR20210008501A (ko) 2018-05-09 2021-01-22 바이오마린 파머수티컬 인크. 페닐케톤뇨증을 치료하는 방법
TW202005978A (zh) 2018-05-14 2020-02-01 美商拜奧馬林製藥公司 新穎肝靶向腺相關病毒載體
CA3102968A1 (en) * 2018-06-12 2019-12-19 Codexis, Inc. Engineered tyrosine ammonia lyase
EP3820833A4 (en) * 2018-07-12 2022-08-03 Codexis, Inc. MODIFIED AMMONIA-LYASE PHENYLALANINE POLYPEPTIDES
SG11202105668PA (en) 2018-12-14 2021-06-29 Codexis Inc Engineered tyrosine ammonia lyase
CA3123598A1 (en) 2018-12-20 2020-06-25 Codexis, Inc. Human alpha-galactosidase variants
CN110456056A (zh) * 2019-07-22 2019-11-15 浙江大学 一种新生儿苯丙酮尿症无创筛查试纸的制备方法
JP2022545718A (ja) 2019-08-30 2022-10-28 コデクシス， インコーポレイテッド 操作されたリパーゼ改変体
EP4077679A4 (en) 2019-12-20 2024-04-24 Codexis Inc MODIFIED ACID ALPHA-GLUCOSIDASE VARIANTS
AR122409A1 (es) 2020-04-03 2022-09-07 Biomarin Pharm Inc Tratamiento de la fenilcetonuria con aav y formulaciones terapéuticas
BR112023003643A2 (pt) 2020-08-28 2023-03-28 Codexis Inc Amilase recombinante, composição, sequência de polinucleotídeo recombinante, vetor de expressão, célula hospedeira, métodos para produzir uma amilase recombinante e para tratar e/ou prevenir os sintomas de insuficiência pancreática, composição farmacêutica para o tratamento de insuficiência pancreática, e, uso
JP2023539632A (ja) 2020-08-28 2023-09-15 コデクシス， インコーポレイテッド 操作されたプロテアーゼバリアント
EP4341394A1 (en) * 2021-05-19 2024-03-27 BioMarin Pharmaceutical Inc. Compositions of prokaryotic phenylalanine ammonia-lyase and methods of treating adolescent subjects
WO2023044381A1 (en) * 2021-09-16 2023-03-23 Arcturus Therapeutics, Inc. Compositions and methods for treating phenylketonuria
CN117417925A (zh) * 2022-07-18 2024-01-19 浙江泽科塔生物医药有限公司 Pal变体、包含该pal变体的药物组合物以及用于制备该pal变体的方法
CN116478975B (zh) * 2023-06-16 2023-09-01 苏州优信合生技术有限公司 高活性苯丙氨酸解氨酶突变体及其表达菌株

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US4562151A (en) * 1983-09-06 1985-12-31 Monsanto Company Stabilization of L-phenylalanine ammonia-lyase enzyme
US5206344A (en) * 1985-06-26 1993-04-27 Cetus Oncology Corporation Interleukin-2 muteins and polymer conjugation thereof
US5166322A (en) 1989-04-21 1992-11-24 Genetics Institute Cysteine added variants of interleukin-3 and chemical modifications thereof
US5766897A (en) * 1990-06-21 1998-06-16 Incyte Pharmaceuticals, Inc. Cysteine-pegylated proteins
PT668933E (pt) * 1992-11-19 2003-02-28 Anticancer Inc Utilizacao de metioninase como agente anti-tumor em qimioterapia anti-metionina
CA2149922C (en) * 1992-12-04 2007-05-15 Thomas W. Macallister Genetically engineered glutaminase and its use in antiviral and anticancer therapy
DK75593D0 (no) * 1993-06-25 1993-06-25 Novo Nordisk As
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AU2001294774A1 (en) * 2000-09-26 2002-04-08 The Regents Of The University Of California Characterization of phenylalanine ammonia-lyase (pal) gene in wounded lettuce
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US7537923B2 (en) * 2007-08-17 2009-05-26 Biomarin Pharmaceutical Inc. Compositions of prokaryotic phenylalanine ammonia-lyase and methods of treating cancer using compositions thereof

Also Published As

Publication number Publication date
AU2008263190A1 (en) 2008-12-18
TW200902052A (en) 2009-01-16
WO2008153776A1 (en) 2008-12-18
HRP20151268T1 (hr) 2015-12-18
US7534595B2 (en) 2009-05-19
CY2019039I2 (el) 2020-05-29
DK2152868T3 (en) 2015-11-16
EP2657335A1 (en) 2013-10-30
AU2008263190B2 (en) 2014-04-17
SI2152868T1 (sl) 2015-12-31
AR110834A2 (es) 2019-05-08
AR066716A1 (es) 2009-09-09
NL301011I2 (nl) 2020-05-13
KR101603796B1 (ko) 2016-03-17
CN101842482A (zh) 2010-09-22
LUC00133I2 (no) 2020-07-16
ES2551315T3 (es) 2015-11-18
US20080008695A1 (en) 2008-01-10
PE20090315A1 (es) 2009-03-19
CY2019039I1 (el) 2020-05-29
IL202132A (en) 2017-06-29
EA018443B1 (ru) 2013-08-30
TWI418633B (zh) 2013-12-11
PL2152868T3 (pl) 2016-01-29
HUE025784T2 (en) 2016-05-30
WO2008153776A8 (en) 2009-07-30
JP2010529835A (ja) 2010-09-02
PT2152868E (pt) 2015-11-13
BRPI0811267B8 (pt) 2021-05-25
LTC2152868I2 (lt) 2020-09-25
HK1135141A1 (zh) 2010-05-28
KR20150038753A (ko) 2015-04-08
LTPA2019517I1 (lt) 2019-10-25
BRPI0811267A2 (pt) 2014-10-07
CA2687450C (en) 2019-03-26
HUS1900049I1 (hu) 2019-11-28
NL301011I1 (nl) 2019-10-16
CL2008001497A1 (es) 2009-01-09
KR20100024437A (ko) 2010-03-05
EA200970980A1 (ru) 2010-04-30
LUC00133I1 (no) 2019-10-16
MX2009012453A (es) 2010-01-25
IL202132A0 (en) 2010-06-16
CY1116894T1 (el) 2017-04-05
EP2152868B1 (en) 2015-09-02
JP5670183B2 (ja) 2015-02-18
CA2687450A1 (en) 2008-12-18
CN101842482B (zh) 2014-10-22
MY151413A (en) 2014-05-30
BRPI0811267B1 (pt) 2020-11-10
EP2152868A1 (en) 2010-02-17

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