LUC00133I2 - - Google Patents

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Publication number
LUC00133I2
LUC00133I2 LU00133C LUC00133C LUC00133I2 LU C00133 I2 LUC00133 I2 LU C00133I2 LU 00133 C LU00133 C LU 00133C LU C00133 C LUC00133 C LU C00133C LU C00133 I2 LUC00133 I2 LU C00133I2
Authority
LU
Luxembourg
Application number
LU00133C
Original Assignee
Biomarin Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39868905&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LUC00133(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Biomarin Pharm Inc filed Critical Biomarin Pharm Inc
Publication of LUC00133I1 publication Critical patent/LUC00133I1/fr
Publication of LUC00133I2 publication Critical patent/LUC00133I2/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/51Lyases (4)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88Lyases (4.)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
LU00133C 2007-05-25 2019-10-14 LUC00133I2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/807,227 US7534595B2 (en) 2006-06-12 2007-05-25 Compositions of prokaryotic phenylalanine ammonia-lyase and methods of using compositions thereof
LU2008006661 2008-05-23

Publications (2)

Publication Number Publication Date
LUC00133I1 LUC00133I1 (fr) 2019-10-16
LUC00133I2 true LUC00133I2 (fr) 2020-07-16

Family

ID=39868905

Family Applications (1)

Application Number Title Priority Date Filing Date
LU00133C LUC00133I2 (fr) 2007-05-25 2019-10-14

Country Status (30)

Country Link
US (1) US7534595B2 (fr)
EP (2) EP2152868B1 (fr)
JP (1) JP5670183B2 (fr)
KR (2) KR20150038753A (fr)
CN (1) CN101842482B (fr)
AR (2) AR066716A1 (fr)
AU (1) AU2008263190B2 (fr)
BR (1) BRPI0811267B8 (fr)
CA (1) CA2687450C (fr)
CL (1) CL2008001497A1 (fr)
CY (2) CY1116894T1 (fr)
DK (1) DK2152868T3 (fr)
EA (1) EA018443B1 (fr)
ES (1) ES2551315T3 (fr)
HK (1) HK1135141A1 (fr)
HR (1) HRP20151268T1 (fr)
HU (2) HUE025784T2 (fr)
IL (1) IL202132A (fr)
LT (1) LTC2152868I2 (fr)
LU (1) LUC00133I2 (fr)
MX (1) MX2009012453A (fr)
MY (1) MY151413A (fr)
NL (1) NL301011I2 (fr)
NO (1) NO2019037I1 (fr)
PE (1) PE20090315A1 (fr)
PL (1) PL2152868T3 (fr)
PT (1) PT2152868E (fr)
SI (1) SI2152868T1 (fr)
TW (1) TWI418633B (fr)
WO (1) WO2008153776A1 (fr)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7534595B2 (en) * 2006-06-12 2009-05-19 Biomarin Pharmaceutical Inc. Compositions of prokaryotic phenylalanine ammonia-lyase and methods of using compositions thereof
US7531341B1 (en) 2006-06-12 2009-05-12 Biomarin Pharmaceutical Inc. Compositions of prokaryotic phenylalanine ammonia-lyase and methods of using compositions thereof
US7537923B2 (en) * 2007-08-17 2009-05-26 Biomarin Pharmaceutical Inc. Compositions of prokaryotic phenylalanine ammonia-lyase and methods of treating cancer using compositions thereof
WO2010014225A2 (fr) 2008-07-30 2010-02-04 Biomarin Pharmaceutical Inc. Dosages permettant la détection de la phénylalanine ammoniac-lyase et des anticorps contre la phénylalanine ammoniac-lyase
CA2782444C (fr) * 2010-02-04 2018-10-23 Biomarin Pharmaceutical Inc. Compositions de variants procaryotes de phenylalanine ammonia-lyase et procedes d'utilisation de compositions les comprenant
WO2014018832A1 (fr) * 2012-07-27 2014-01-30 University Of North Texas Probiotique génétiquement modifié (gmp) pour le traitement de la phénylcétonurie (pku)
MY193198A (en) 2013-04-18 2022-09-26 Codexis Inc Engineered phenylalanine ammonia lyase polypeptides
WO2015073587A2 (fr) 2013-11-18 2015-05-21 Rubius Therapeutics, Inc. Complexes membrane synthétique- récepteur
MA39819A (fr) 2014-04-01 2017-02-08 Rubius Therapeutics Inc Méthodes et compositions d'immunomodulation
HUE056444T2 (hu) 2014-04-16 2022-02-28 Codexis Inc Génmódosított tirozin-ammónia-liáz
KR102438885B1 (ko) 2014-12-22 2022-09-01 코덱시스, 인코포레이티드 인간 알파-갈락토시다제 변이체
TW202340452A (zh) * 2015-08-04 2023-10-16 美商再生元醫藥公司 補充牛磺酸之細胞培養基及用法
WO2018022608A2 (fr) 2016-07-26 2018-02-01 Biomarin Pharmaceutical Inc. Nouvelles protéines de capside de virus adéno-associés
MY190749A (en) * 2016-08-30 2022-05-12 Mitsubishi Chem Corp Method for producing mutant enzyme, and mutant alcohol acyltransferase
CN106497905A (zh) * 2016-12-14 2017-03-15 江南大学 一株鱼腥藻来源的苯丙氨酸脱氨酶的突变体
BR112019016634A2 (pt) 2017-02-13 2020-04-07 Codexis Inc polipeptídeos, sequência de polinucleotídeos modificados por engenharia, vetor de expressão, célula hospedeira, métodos para produzir um polipeptídeo de fenilalanina amônia liase modificado por engenharia em uma célula hospedeira e para tratar e/ou prevenir os sintomas de fenilcetonúria em um indivíduo, composição, e, uso
CN107653275A (zh) * 2017-10-30 2018-02-02 安徽工程大学 D‑苯丙氨酸的制备方法
CN108004225B (zh) * 2017-12-19 2020-05-08 江南大学 一种成团泛菌来源的苯丙氨酸氨基变位酶的突变体
EP3790627A2 (fr) 2018-05-09 2021-03-17 BioMarin Pharmaceutical Inc. Méthodes de traitement de la grippe
TW202005978A (zh) 2018-05-14 2020-02-01 美商拜奧馬林製藥公司 新穎肝靶向腺相關病毒載體
WO2019241132A1 (fr) 2018-06-12 2019-12-19 Codexis, Inc. Tyrosine ammonia-lyase modifiée
US11198861B2 (en) * 2018-07-12 2021-12-14 Codexis, Inc. Engineered phenylalanine ammonia lyase polypeptides
SG11202105668PA (en) 2018-12-14 2021-06-29 Codexis Inc Engineered tyrosine ammonia lyase
EP3898960A4 (fr) 2018-12-20 2022-11-30 Codexis, Inc. Variants d'alpha-galactosidase humaine
CN110456056A (zh) * 2019-07-22 2019-11-15 浙江大学 一种新生儿苯丙酮尿症无创筛查试纸的制备方法
AR122409A1 (es) 2020-04-03 2022-09-07 Biomarin Pharm Inc Tratamiento de la fenilcetonuria con aav y formulaciones terapéuticas
BR112023003643A2 (pt) 2020-08-28 2023-03-28 Codexis Inc Amilase recombinante, composição, sequência de polinucleotídeo recombinante, vetor de expressão, célula hospedeira, métodos para produzir uma amilase recombinante e para tratar e/ou prevenir os sintomas de insuficiência pancreática, composição farmacêutica para o tratamento de insuficiência pancreática, e, uso
US11959108B2 (en) 2020-08-28 2024-04-16 Codexis, Inc. Engineered protease variants
EP4341394A1 (fr) * 2021-05-19 2024-03-27 BioMarin Pharmaceutical Inc. Compositions de phénylalanine ammonia-lyase procaryotique et méthodes de traitement de sujets adolescents
WO2023044381A1 (fr) * 2021-09-16 2023-03-23 Arcturus Therapeutics, Inc. Compositions et procédés de traitement de la phénylcétonurie
CN117417925A (zh) * 2022-07-18 2024-01-19 浙江泽科塔生物医药有限公司 Pal变体、包含该pal变体的药物组合物以及用于制备该pal变体的方法
CN116478975B (zh) * 2023-06-16 2023-09-01 苏州优信合生技术有限公司 高活性苯丙氨酸解氨酶突变体及其表达菌株

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Also Published As

Publication number Publication date
CY1116894T1 (el) 2017-04-05
EA018443B1 (ru) 2013-08-30
MY151413A (en) 2014-05-30
EP2657335A1 (fr) 2013-10-30
JP2010529835A (ja) 2010-09-02
CA2687450C (fr) 2019-03-26
LTPA2019517I1 (lt) 2019-10-25
CN101842482B (zh) 2014-10-22
US7534595B2 (en) 2009-05-19
EP2152868B1 (fr) 2015-09-02
AU2008263190A1 (en) 2008-12-18
BRPI0811267B1 (pt) 2020-11-10
EP2152868A1 (fr) 2010-02-17
NO2019037I1 (no) 2019-10-16
AR066716A1 (es) 2009-09-09
KR20150038753A (ko) 2015-04-08
WO2008153776A8 (fr) 2009-07-30
BRPI0811267B8 (pt) 2021-05-25
SI2152868T1 (sl) 2015-12-31
PL2152868T3 (pl) 2016-01-29
CL2008001497A1 (es) 2009-01-09
IL202132A (en) 2017-06-29
KR101603796B1 (ko) 2016-03-17
AR110834A2 (es) 2019-05-08
LUC00133I1 (fr) 2019-10-16
ES2551315T3 (es) 2015-11-18
EA200970980A1 (ru) 2010-04-30
DK2152868T3 (en) 2015-11-16
CA2687450A1 (fr) 2008-12-18
HRP20151268T1 (hr) 2015-12-18
NL301011I2 (nl) 2020-05-13
MX2009012453A (es) 2010-01-25
LTC2152868I2 (lt) 2020-09-25
TWI418633B (zh) 2013-12-11
CY2019039I2 (el) 2020-05-29
JP5670183B2 (ja) 2015-02-18
TW200902052A (en) 2009-01-16
BRPI0811267A2 (pt) 2014-10-07
PT2152868E (pt) 2015-11-13
AU2008263190B2 (en) 2014-04-17
HUS1900049I1 (hu) 2019-11-28
CN101842482A (zh) 2010-09-22
WO2008153776A1 (fr) 2008-12-18
KR20100024437A (ko) 2010-03-05
US20080008695A1 (en) 2008-01-10
PE20090315A1 (es) 2009-03-19
IL202132A0 (en) 2010-06-16
HK1135141A1 (zh) 2010-05-28
NL301011I1 (nl) 2019-10-16
CY2019039I1 (el) 2020-05-29
HUE025784T2 (en) 2016-05-30

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