NO20092960L - Krystallinsk minocycline base og framgangsmater for framstilling av denne - Google Patents
Krystallinsk minocycline base og framgangsmater for framstilling av denneInfo
- Publication number
- NO20092960L NO20092960L NO20092960A NO20092960A NO20092960L NO 20092960 L NO20092960 L NO 20092960L NO 20092960 A NO20092960 A NO 20092960A NO 20092960 A NO20092960 A NO 20092960A NO 20092960 L NO20092960 L NO 20092960L
- Authority
- NO
- Norway
- Prior art keywords
- minocycline base
- processes
- preparation
- crystalline
- crystalline minocycline
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/24—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton
- C07C237/26—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton of a ring being part of a condensed ring system formed by at least four rings, e.g. tetracycline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/65—Tetracyclines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PT103661A PT103661B (pt) | 2007-02-23 | 2007-02-23 | Processo de preparação de minociclina base cristalina |
PCT/GB2008/000625 WO2008102161A2 (en) | 2007-02-23 | 2008-02-22 | Crystalline minocycline base and processes for its preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20092960L true NO20092960L (no) | 2009-11-20 |
Family
ID=39432804
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20092960A NO20092960L (no) | 2007-02-23 | 2009-09-04 | Krystallinsk minocycline base og framgangsmater for framstilling av denne |
Country Status (20)
Country | Link |
---|---|
US (2) | US8258327B2 (pt) |
EP (1) | EP2125705B1 (pt) |
JP (4) | JP2010519247A (pt) |
KR (1) | KR101391132B1 (pt) |
CN (1) | CN101679218B (pt) |
AU (1) | AU2008217619B2 (pt) |
BR (2) | BRPI0807319B1 (pt) |
CA (2) | CA2835788C (pt) |
DK (1) | DK2125705T3 (pt) |
ES (1) | ES2610434T3 (pt) |
HU (1) | HUE033030T2 (pt) |
IL (1) | IL200544A0 (pt) |
MX (2) | MX2009008980A (pt) |
NO (1) | NO20092960L (pt) |
NZ (1) | NZ579626A (pt) |
PL (1) | PL2125705T3 (pt) |
PT (1) | PT103661B (pt) |
RU (2) | RU2485095C2 (pt) |
WO (1) | WO2008102161A2 (pt) |
ZA (1) | ZA200906517B (pt) |
Families Citing this family (33)
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IL152486A0 (en) | 2002-10-25 | 2003-05-29 | Meir Eini | Alcohol-free cosmetic and pharmaceutical foam carrier |
US9668972B2 (en) | 2002-10-25 | 2017-06-06 | Foamix Pharmaceuticals Ltd. | Nonsteroidal immunomodulating kit and composition and uses thereof |
US7704518B2 (en) | 2003-08-04 | 2010-04-27 | Foamix, Ltd. | Foamable vehicle and pharmaceutical compositions thereof |
US7700076B2 (en) | 2002-10-25 | 2010-04-20 | Foamix, Ltd. | Penetrating pharmaceutical foam |
US20080138296A1 (en) | 2002-10-25 | 2008-06-12 | Foamix Ltd. | Foam prepared from nanoemulsions and uses |
CA2502986C (en) | 2002-10-25 | 2011-08-23 | Foamix Ltd. | Cosmetic and pharmaceutical foam |
US9265725B2 (en) | 2002-10-25 | 2016-02-23 | Foamix Pharmaceuticals Ltd. | Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof |
US10117812B2 (en) | 2002-10-25 | 2018-11-06 | Foamix Pharmaceuticals Ltd. | Foamable composition combining a polar solvent and a hydrophobic carrier |
US9211259B2 (en) | 2002-11-29 | 2015-12-15 | Foamix Pharmaceuticals Ltd. | Antibiotic kit and composition and uses thereof |
US8722650B1 (en) | 2005-06-24 | 2014-05-13 | Medicis Pharmaceutical Corporation | Extended-release minocycline dosage forms |
US20080242642A1 (en) | 2007-04-02 | 2008-10-02 | Medicis Pharmaceutical Corporation | Minocycline oral dosage forms for the treatment of acne |
US20080260655A1 (en) | 2006-11-14 | 2008-10-23 | Dov Tamarkin | Substantially non-aqueous foamable petrolatum based pharmaceutical and cosmetic compositions and their uses |
PT103661B (pt) | 2007-02-23 | 2010-09-07 | Hovione Farmaciencia S A | Processo de preparação de minociclina base cristalina |
US8636982B2 (en) | 2007-08-07 | 2014-01-28 | Foamix Ltd. | Wax foamable vehicle and pharmaceutical compositions thereof |
US9439857B2 (en) | 2007-11-30 | 2016-09-13 | Foamix Pharmaceuticals Ltd. | Foam containing benzoyl peroxide |
WO2009090495A2 (en) | 2007-12-07 | 2009-07-23 | Foamix Ltd. | Oil and liquid silicone foamable carriers and formulations |
WO2010017310A1 (en) | 2008-08-06 | 2010-02-11 | Medicis Pharmaceutical Corporation | Method for the treatment of acne and certain dosage forms thereof |
PT104350A (pt) * | 2009-01-23 | 2010-07-23 | Hovione Farmaci Ncia S A | Processo de isolamento de tigeciclina |
CA2760186C (en) | 2009-04-28 | 2019-10-29 | Foamix Ltd. | Foamable vehicle and pharmaceutical compositions comprising aprotic polar solvents and uses thereof |
PT104644B (pt) | 2009-06-26 | 2012-11-06 | Hovione Farmaciencia S A | Formulação tópica contendo uma tetraciclina e método de tratamento de infecções cutâneas usando a mesma |
WO2011013009A2 (en) | 2009-07-29 | 2011-02-03 | Foamix Ltd. | Non surfactant hydro-alcoholic foamable compositions, breakable foams and their uses |
CA2769677A1 (en) | 2009-07-29 | 2011-02-03 | Foamix Ltd. | Non surface active agent non polymeric agent hydro-alcoholic foamable compositions, breakable foams and their uses |
MX359879B (es) | 2009-10-02 | 2018-10-12 | Foamix Pharmaceuticals Ltd | Composiciones tópicas de tetraciclina. |
US9849142B2 (en) | 2009-10-02 | 2017-12-26 | Foamix Pharmaceuticals Ltd. | Methods for accelerated return of skin integrity and for the treatment of impetigo |
US9561241B1 (en) | 2011-06-28 | 2017-02-07 | Medicis Pharmaceutical Corporation | Gastroretentive dosage forms for minocycline |
PT106063B (pt) * | 2011-12-19 | 2017-05-30 | Inst Superior Técnico | Minociclina cristalina termorresistente produzida por recristalização com dióxido de carbono |
CN104151186B (zh) * | 2014-08-11 | 2016-06-15 | 重庆福安药业(集团)股份有限公司 | 替加环素杂质的立体选择性制备方法 |
PT108223B (pt) * | 2015-02-13 | 2018-05-08 | Hovione Farm S A | Novas formas polimórficas de minociclina base e processos para a sua preparação |
TW201705962A (zh) | 2015-03-23 | 2017-02-16 | 生物製藥X公司 | 皮膚用四環素醫藥組成物 |
WO2017097891A1 (en) * | 2015-12-10 | 2017-06-15 | Sandoz Ag | Crystalline eravacycline |
MX2020012139A (es) | 2016-09-08 | 2021-01-29 | Vyne Pharmaceuticals Inc | Composiciones y metodos para tratar rosacea y acne. |
WO2021191273A1 (en) | 2020-03-24 | 2021-09-30 | Hovione Scientia Limited | Compositions for use in treating meibomian gland dysfunction |
WO2022043457A1 (en) | 2020-08-27 | 2022-03-03 | Hovione Scientia Limited | Methods and compositions for treating rosacea |
Family Cites Families (21)
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US299111A (en) * | 1884-05-27 | Process of and apparatus | ||
US3148212A (en) | 1961-12-22 | 1964-09-08 | American Cyanamid Co | Reductive alkylation process |
USRE26253E (en) | 1963-05-17 | 1967-08-15 | And z-alkylamino-g-deoxytetracycline | |
US3526629A (en) * | 1968-04-02 | 1970-09-01 | American Cyanamid Co | Beta-hydroxyethylpiperazinocarboxymethyl - 7 - dimethylamino - 6 - deoxy-6-demethyltetracycline |
JPS5245716B1 (pt) * | 1970-07-10 | 1977-11-17 | ||
CA999855A (en) * | 1972-09-18 | 1976-11-16 | Societa' Farmaceutici Italia S.P.A. | Process for the preparation of tetracyclines derivatives in the 7 position |
CN85101404A (zh) * | 1985-05-16 | 1987-01-17 | 帝人株式会社 | 头孢菌素衍生物的生产过程 |
JPH0737433B2 (ja) | 1987-06-11 | 1995-04-26 | 協和醗酵工業株式会社 | 7−アミノ−6−デメチル−6−デオキシテトラサイクリンの製造法 |
US5202449A (en) * | 1987-07-28 | 1993-04-13 | Nippon Kayaku Kabushiki Kaisha | Process for purifying 7-dimethylamino-6-demethyl-6-deoxytetracycline |
US4918208A (en) * | 1987-07-28 | 1990-04-17 | Nippon Kayaku Kabushiki Kaisha | Process for producing 7-dimethylamino-6-demethyl-6-deoxytetracycline |
JPH04235188A (ja) * | 1990-06-19 | 1992-08-24 | Takeda Chem Ind Ltd | ペネム化合物の結晶、その製造方法および抗菌剤 |
US5262173A (en) * | 1992-03-02 | 1993-11-16 | American Cyanamid Company | Pulsatile once-a-day delivery systems for minocycline |
DE4235133A1 (de) * | 1992-10-19 | 1994-04-21 | Bayer Ag | Kristallines (R)-(-)-2-Cycloheptyl-N-methylsulfonyl-[4-(2-chinolinyl-methoxy)-phenyl]-acetamid |
JP3623531B2 (ja) * | 1993-06-07 | 2005-02-23 | ビーエーエスエフ アクチェンゲゼルシャフト | 結晶質l−アスコルビン酸−2−燐酸エステルマグネシウム塩の製造法 |
CZ294108B6 (cs) * | 1995-07-17 | 2004-10-13 | Warner@Lambertácompany | Krystalická forma I hydrátu atorvastatinuŹ tj@ semivápenaté soli kyseliny [R@}RgŹRgB]@}@fluorfenylB@betaŹdelta@dihydroxy@Q@}�@methylethylB@fenyl[}fenylaminoBkarbonyl]@�H@pyrrol@�@heptanové |
IL136460A0 (en) | 1997-12-22 | 2001-06-14 | Schering Corp | Molecular dispersion composition with enhanced bioavailability |
AU1405400A (en) * | 1998-12-01 | 2000-06-19 | Atropos Limited | A medical device comprising an evertable sleeve |
CL2004001884A1 (es) * | 2003-08-04 | 2005-06-03 | Pfizer Prod Inc | Procedimiento de secado por pulverizacion para la formacion de dispersiones solidas amorfas de un farmaco y polimeros. |
AR057649A1 (es) * | 2005-05-27 | 2007-12-12 | Wyeth Corp | Formas solidas cristalinas de tigeciclina y metodos para preparar las mismas |
US20070093455A1 (en) * | 2005-07-21 | 2007-04-26 | Paul Abato | 10-substituted tetracyclines and methods of use thereof |
PT103661B (pt) | 2007-02-23 | 2010-09-07 | Hovione Farmaciencia S A | Processo de preparação de minociclina base cristalina |
-
2007
- 2007-02-23 PT PT103661A patent/PT103661B/pt active IP Right Grant
-
2008
- 2008-02-22 CA CA2835788A patent/CA2835788C/en active Active
- 2008-02-22 BR BRPI0807319-8A patent/BRPI0807319B1/pt active IP Right Grant
- 2008-02-22 WO PCT/GB2008/000625 patent/WO2008102161A2/en active Application Filing
- 2008-02-22 CA CA2722496A patent/CA2722496C/en active Active
- 2008-02-22 BR BR122021000846-9A patent/BR122021000846B1/pt active IP Right Grant
- 2008-02-22 EP EP08709507.1A patent/EP2125705B1/en active Active
- 2008-02-22 AU AU2008217619A patent/AU2008217619B2/en active Active
- 2008-02-22 NZ NZ579626A patent/NZ579626A/en unknown
- 2008-02-22 HU HUE08709507A patent/HUE033030T2/hu unknown
- 2008-02-22 ES ES08709507.1T patent/ES2610434T3/es active Active
- 2008-02-22 US US12/528,209 patent/US8258327B2/en active Active
- 2008-02-22 PL PL08709507T patent/PL2125705T3/pl unknown
- 2008-02-22 MX MX2009008980A patent/MX2009008980A/es active IP Right Grant
- 2008-02-22 KR KR1020097019750A patent/KR101391132B1/ko active IP Right Grant
- 2008-02-22 RU RU2009135403/04A patent/RU2485095C2/ru active
- 2008-02-22 RU RU2013112021/04A patent/RU2577331C2/ru active
- 2008-02-22 JP JP2009550320A patent/JP2010519247A/ja not_active Withdrawn
- 2008-02-22 DK DK08709507.1T patent/DK2125705T3/en active
- 2008-02-22 CN CN2008800059328A patent/CN101679218B/zh active Active
-
2009
- 2009-08-21 MX MX2012005474A patent/MX340539B/es unknown
- 2009-08-23 IL IL200544A patent/IL200544A0/en active IP Right Grant
- 2009-09-04 NO NO20092960A patent/NO20092960L/no not_active Application Discontinuation
- 2009-09-18 ZA ZA200906517A patent/ZA200906517B/en unknown
-
2012
- 2012-08-30 US US13/599,116 patent/US9416097B2/en active Active
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2014
- 2014-05-20 JP JP2014104022A patent/JP2014169319A/ja active Pending
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2016
- 2016-09-28 JP JP2016189162A patent/JP2017039742A/ja active Pending
-
2019
- 2019-03-27 JP JP2019059559A patent/JP2019142882A/ja active Pending
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
CHAD | Change of the owner's name or address (par. 44 patent law, par. patentforskriften) |
Owner name: HOVIONE SCIENTIA LIMITED, IE |
|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |