NO20050860L - Fremgangsmate for fremstilling av krystallinske nanopartikkeldispersjoner - Google Patents

Fremgangsmate for fremstilling av krystallinske nanopartikkeldispersjoner

Info

Publication number
NO20050860L
NO20050860L NO20050860A NO20050860A NO20050860L NO 20050860 L NO20050860 L NO 20050860L NO 20050860 A NO20050860 A NO 20050860A NO 20050860 A NO20050860 A NO 20050860A NO 20050860 L NO20050860 L NO 20050860L
Authority
NO
Norway
Prior art keywords
preparation
dispersion
water
insoluble substance
amorphous particles
Prior art date
Application number
NO20050860A
Other languages
English (en)
Norwegian (no)
Inventor
Per Lennart Lindfors
Tommy Urban Skantze
Sara Forssen
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of NO20050860L publication Critical patent/NO20050860L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5138—Organic macromolecular compounds; Dendrimers obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y40/00—Manufacture or treatment of nanostructures

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Biomedical Technology (AREA)
  • Dispersion Chemistry (AREA)
  • Colloid Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Medicinal Preparation (AREA)
  • Iron Core Of Rotating Electric Machines (AREA)
  • Glass Compositions (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
  • Mixers With Rotating Receptacles And Mixers With Vibration Mechanisms (AREA)
  • Pigments, Carbon Blacks, Or Wood Stains (AREA)
NO20050860A 2002-07-18 2005-02-17 Fremgangsmate for fremstilling av krystallinske nanopartikkeldispersjoner NO20050860L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0216700.5A GB0216700D0 (en) 2002-07-18 2002-07-18 Process
PCT/GB2003/003044 WO2004009057A1 (en) 2002-07-18 2003-07-14 Process for the preparation of crystalline nano-particle dispersions

Publications (1)

Publication Number Publication Date
NO20050860L true NO20050860L (no) 2005-04-18

Family

ID=9940704

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20050860A NO20050860L (no) 2002-07-18 2005-02-17 Fremgangsmate for fremstilling av krystallinske nanopartikkeldispersjoner

Country Status (18)

Country Link
US (1) US7780989B2 (es)
EP (1) EP1524964B1 (es)
JP (1) JP2006504511A (es)
KR (1) KR101061309B1 (es)
CN (1) CN100594885C (es)
AT (1) ATE489939T1 (es)
BR (1) BR0312631A (es)
CA (1) CA2492709C (es)
DE (1) DE60335189D1 (es)
ES (1) ES2355137T3 (es)
GB (1) GB0216700D0 (es)
HK (1) HK1075199A1 (es)
IL (1) IL165930A0 (es)
MX (1) MXPA05000595A (es)
NO (1) NO20050860L (es)
NZ (1) NZ537654A (es)
WO (1) WO2004009057A1 (es)
ZA (1) ZA200410343B (es)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002317409B2 (en) * 2001-08-06 2007-06-21 Astrazeneca Ab Aqueous dispersion comprising stable nanoparticles of a water-insoluble active and an excipient like middle chain triglycerides (MCT)
GB0230087D0 (en) * 2002-12-24 2003-01-29 Astrazeneca Ab Therapeutic agents
GB0230088D0 (en) * 2002-12-24 2003-01-29 Astrazeneca Ab Therapeutic agents
GB0302673D0 (en) * 2003-02-06 2003-03-12 Astrazeneca Ab Pharmaceutical formulations
GB0302671D0 (en) * 2003-02-06 2003-03-12 Astrazeneca Ab Pharmaceutical formulations
GB0302672D0 (en) * 2003-02-06 2003-03-12 Astrazeneca Ab Pharmaceutical formulations
US20050008691A1 (en) * 2003-05-14 2005-01-13 Arturo Siles Ortega Bicalutamide compositions
GB0314057D0 (en) * 2003-06-18 2003-07-23 Astrazeneca Ab Therapeutic agents
JP2006527770A (ja) * 2003-06-18 2006-12-07 アストラゼネカ アクチボラグ Ｃｂ１モジュレーターとしての２−置換５，６−ジアリール−ピラジン誘導体
GB0314261D0 (en) * 2003-06-19 2003-07-23 Astrazeneca Ab Therapeutic agents
US7326706B2 (en) * 2003-08-15 2008-02-05 Bristol-Myers Squibb Company Pyrazine modulators of cannabinoid receptors
FR2861992B1 (fr) * 2003-11-10 2007-07-20 Sanofi Synthelabo Composition pharmaceutique destinee a l'administration orale d'un derive de pyrazole-3-carboxamide.
IL160858A (en) * 2004-03-14 2015-09-24 Adama Makhteshim Ltd Nano-pesticide pesticide preparation and process for preparation
WO2005123721A2 (en) * 2004-06-18 2005-12-29 Ranbaxy Laboratories Limited Amorphous and polymorphic forms of candesartan cilexetil
AU2005260816B2 (en) * 2004-07-14 2010-12-16 Sumitomo Chemical Company, Limited Method of crystallizing bicalutamide
US20060159767A1 (en) * 2004-12-22 2006-07-20 Elan Pharma International Limited Nanoparticulate bicalutamide formulations
EP1835890A2 (en) * 2005-01-06 2007-09-26 Elan Pharma International Limited Nanoparticulate candesartan formulations
WO2006113309A1 (en) * 2005-04-15 2006-10-26 Dr. Reddy's Laboratories Ltd. Lacidipine particles
JP2007038117A (ja) * 2005-08-02 2007-02-15 Fujifilm Holdings Corp 粒子製造方法
JP2009519125A (ja) * 2005-12-13 2009-05-14 コミッサリア タ レネルジー アトミーク ナノメータ規模及びサブマイクロメータ規模の微粒子の浮遊体を生成するためのデバイス及び方法
JPWO2007072869A1 (ja) * 2005-12-21 2009-06-04 エーザイ・アール・アンド・ディー・マネジメント株式会社 １，２−ジヒドロピリジン化合物の非晶質体
WO2007103711A2 (en) * 2006-03-01 2007-09-13 Dr. Reddy's Laboratories Ltd. Polymorphic forms of rimonabant
MX2009002425A (es) * 2006-09-05 2009-03-20 Astrazeneca Ab Composicion farmaceutica que comprende candesartan cilexetilo.
US20080217583A1 (en) * 2006-10-20 2008-09-11 James Hayes Aerosol formulations comprising semiconductor nanocrystal compositions and methods of making the same
JP5004333B2 (ja) * 2006-12-08 2012-08-22 日機装株式会社 ナノオーダ粒子製造装置
CN101605533B (zh) * 2007-02-09 2012-04-18 阿斯利康(瑞典)有限公司 制备固体非晶亚微米颗粒在水性介质中的稳定分散体的方法
FR2913018A1 (fr) * 2007-02-23 2008-08-29 Sanofi Aventis Sa Solution solide amorphe contenant un derive de pyrazole-3-carboxamide sous forme amorphe et des excipients stabilisateurs
JP5428058B2 (ja) * 2007-12-28 2014-02-26 ライオン株式会社 微粒化エラグ酸化合物の製造方法
KR20100052262A (ko) * 2008-11-10 2010-05-19 (주)아모레퍼시픽 난용성 약물의 나노입자를 포함하는 분말의 제조방법, 그에의해 제조된 분말 및 이를 포함하는 약학적 조성물
EP2442794A1 (en) * 2009-06-19 2012-04-25 Nanoform Hungary Ltd. Nanoparticulate telmisartan compositions and process for the preparation thereof
HUP0900384A2 (en) * 2009-06-19 2011-01-28 Nangenex Nanotechnologiai Zartkoerueen Muekoedoe Reszvenytarsasag Nanoparticulate olmesartan medoxomil compositions
HUP0900376A2 (en) * 2009-06-19 2011-01-28 Nangenex Nanotechnologiai Zartkoerueen Muekoedoe Reszvenytarsasag Nanoparticulate candesartan cilexetil composition
RU2411133C1 (ru) * 2009-08-07 2011-02-10 Общество С Ограниченной Ответственностью "Новые Энергетические Технологии" Вещество метки подлинности банкнот, ценных бумаг и документов и способ его приготовления
GB0918431D0 (en) 2009-10-21 2009-12-09 Prosonix Ltd Process for improving crystallinity
US8920682B2 (en) * 2010-03-19 2014-12-30 Eastern Michigan University Nanoparticle dispersions with ionic liquid-based stabilizers
WO2012000757A1 (en) * 2010-06-30 2012-01-05 Unilever Nv Particles comprising hydrophobic polymer and hydrophobic phenolic compound
CN102048702B (zh) * 2010-12-03 2012-05-23 山东大学 一种联苯双酯纳米结晶制剂及其制备方法
CN102746215A (zh) * 2011-04-18 2012-10-24 张兆勇 一种制备高纯度盐酸贝尼地平的方法
US20140031557A1 (en) * 2011-04-18 2014-01-30 Hefeibeinie Medical Technology Company, Ltd. Method for purification of calcium channel blockers of dihydorpyridine type and preparation of nanoparticles thereof
WO2013041944A1 (en) 2011-09-19 2013-03-28 Ranbaxy Laboratories Limited Process for the preparation of micronized candesartan cilexetil
WO2013066735A1 (en) * 2011-10-31 2013-05-10 Merck Sharp & Dohme Corp. Nano-suspension process
CN102846554B (zh) * 2012-09-28 2014-11-26 山东大学 一种h2纳米结晶制剂及其制备方法
KR102045732B1 (ko) * 2012-12-28 2019-11-18 엘지디스플레이 주식회사 온도감응형 계면활성제를 이용한 수용성 나노입자의 제조방법
CN103145594B (zh) * 2013-03-26 2014-12-17 四川农业大学 一种制备氟苯尼考微晶体的方法
US20170014352A1 (en) * 2014-03-10 2017-01-19 The University Of Tokyo Water-dispersible amorphous particles and method for preparing same
KR102424025B1 (ko) * 2014-12-15 2022-07-22 엠. 테크닉 가부시키가이샤 유기물 미립자의 제조 방법 및 유기물 미립자의 개질 방법
CN107541209B (zh) * 2016-06-28 2020-09-01 苏州大学 一种将油相纳米粒子转移至水相的方法
CN109020807B (zh) * 2017-06-09 2022-06-24 鲁南制药集团股份有限公司 一种肉豆蔻酸钠晶型及其制备方法
CN107595772B (zh) * 2017-09-26 2020-09-18 山东省药学科学院 一种他克莫司纳米混悬滴眼液的制备方法
CN108383887A (zh) * 2018-03-14 2018-08-10 广东润华药业有限公司 一种替米考星纳米结晶的制备方法
CN109260159B (zh) * 2018-11-29 2021-07-23 沈阳药科大学 一种含有艾地苯醌的药物组合物及其制备方法
US20230077636A1 (en) * 2021-08-31 2023-03-16 Natsar Pharmaceuticals, Inc. Intravenous formulations of rk-33

Family Cites Families (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4348385A (en) * 1980-11-17 1982-09-07 Mobay Chemical Corporation Flowable pesticides
DE3119383A1 (de) * 1981-05-15 1982-12-02 Basf Ag, 6700 Ludwigshafen Verfahren zur herstellung von feinverteilten, pulverfoermigen carotinodpraeparaten
JPS5851934A (ja) * 1981-09-21 1983-03-26 Kingo Yoshida 超音波によるアモルフアス物質製造法
US4610868A (en) * 1984-03-20 1986-09-09 The Liposome Company, Inc. Lipid matrix carriers for use in drug delivery systems
US4826689A (en) 1984-05-21 1989-05-02 University Of Rochester Method for making uniformly sized particles from water-insoluble organic compounds
CA1282405C (en) * 1984-05-21 1991-04-02 Michael R. Violante Method for making uniformly sized particles from water-insoluble organic compounds
FR2608988B1 (fr) 1986-12-31 1991-01-11 Centre Nat Rech Scient Procede de preparation de systemes colloidaux dispersibles d'une substance, sous forme de nanoparticules
SE8700213L (sv) 1987-01-21 1988-07-22 Nobel Kemi Ab Sett att framstella kristallina substanser
JP3003148B2 (ja) 1989-01-05 2000-01-24 藤沢薬品工業株式会社 チアゾール化合物、その製造法およびそれを含有する医薬組成物
JPH03188438A (ja) 1989-12-18 1991-08-16 Fuji Photo Film Co Ltd ハロゲン化銀写真感光材料
DE69112917T2 (de) 1990-06-15 1996-05-15 Merck & Co Inc Kristallisationsverfahren zur Verbesserung der Kristallstruktur und -grösse.
US5145684A (en) 1991-01-25 1992-09-08 Sterling Drug Inc. Surface modified drug nanoparticles
MX9201782A (es) 1991-04-19 1992-10-01 Sandoz Ag Particulas de sustancias biologicamente activas, sustancialmente insolubles en agua, proceso para su produccion y composicion farmaceutica que las contiene.
AU671965B2 (en) 1991-12-05 1996-09-19 Alfatec-Pharma Gmbh Pharmaceutically Applicable Nanosol and Process for Preparing The Same
FR2692575B1 (fr) 1992-06-23 1995-06-30 Sanofi Elf Nouveaux derives du pyrazole, procede pour leur preparation et compositions pharmaceutiques les contenant.
US5674514A (en) 1992-09-21 1997-10-07 Ciba-Geigy Corporation Storage stable pesticidal aqueous emulsions
US5468604A (en) * 1992-11-18 1995-11-21 Eastman Kodak Company Photographic dispersion
US5916596A (en) * 1993-02-22 1999-06-29 Vivorx Pharmaceuticals, Inc. Protein stabilized pharmacologically active agents, methods for the preparation thereof and methods for the use thereof
DE19609538A1 (de) * 1996-03-11 1997-09-18 Basf Ag Feinverteilte Carotinoid- und Retinoidsuspensionen und Verfahren zu ihrer Herstellung
GB2276567B (en) 1993-04-03 1996-11-27 Atomic Energy Authority Uk Processing vessel
GB9319129D0 (en) 1993-09-15 1993-11-03 Dowelanco Ltd Storage and dilution of stable aqueous dispersions
SE9303281D0 (sv) 1993-10-07 1993-10-07 Astra Ab New formulation
SE9403846D0 (sv) 1994-11-09 1994-11-09 Univ Ohio State Res Found Small particle formation
DE4440337A1 (de) * 1994-11-11 1996-05-15 Dds Drug Delivery Services Ges Pharmazeutische Nanosuspensionen zur Arzneistoffapplikation als Systeme mit erhöhter Sättigungslöslichkeit und Lösungsgeschwindigkeit
US5665331A (en) * 1995-01-10 1997-09-09 Nanosystems L.L.C. Co-microprecipitation of nanoparticulate pharmaceutical agents with crystal growth modifiers
US5534270A (en) 1995-02-09 1996-07-09 Nanosystems Llc Method of preparing stable drug nanoparticles
SE9501384D0 (sv) 1995-04-13 1995-04-13 Astra Ab Process for the preparation of respirable particles
TW493991B (en) 1995-05-08 2002-07-11 Novartis Ag Pharmaceutical composition for oral administration of active agent having low water solubility and process for preparation of the same
WO1997004756A2 (en) 1995-07-26 1997-02-13 Nanosystems L.L.C. Methacrylate backbone surfactants in nanoparticulate formulations
TW487582B (en) * 1995-08-11 2002-05-21 Nissan Chemical Ind Ltd Method for converting sparingly water-soluble medical substance to amorphous state
US5834025A (en) 1995-09-29 1998-11-10 Nanosystems L.L.C. Reduction of intravenously administered nanoparticulate-formulation-induced adverse physiological reactions
WO1997013503A1 (en) 1995-10-13 1997-04-17 The Penn State Research Foundation Synthesis of drug nanoparticles by spray drying
ATE257698T1 (de) 1996-10-03 2004-01-15 Hermes Biosciences Inc Hydrophile mikropartikel und verfahren zu deren herstellung
GB9624615D0 (en) 1996-11-26 1997-01-15 Zeneca Ltd Chrystallisation process
CN100462066C (zh) 1997-06-27 2009-02-18 美国生物科学有限公司 药剂的新制剂及其制备和应用方法
FR2766368B1 (fr) 1997-07-24 2000-03-31 Univ Claude Bernard Lyon Procede de preparation de nanocapsules de type vesiculaire, utilisables notamment comme vecteurs colloidaux de principes actifs pharmaceutiques ou autres
GB9810859D0 (en) 1998-05-20 1998-07-22 Zeneca Ltd Crystallisation process
DE19856432A1 (de) 1998-12-08 2000-06-15 Basf Ag Nanopartikuläre Kern-Schale Systeme sowie deren Verwendung in pharmazeutischen und kosmetischen Zubereitungen
GB9828721D0 (en) 1998-12-24 1999-02-17 Glaxo Group Ltd Novel apparatus and process
BR0007396A (pt) 1999-01-29 2001-10-30 Bristol Myers Squibb Co Aparelho e processo de cristalização por jato deimpacto sÈnico
FR2789079B3 (fr) 1999-02-01 2001-03-02 Sanofi Synthelabo Derive d'acide pyrazolecarboxylique, sa preparation, les compositions pharmaceutiques en contenant
US6383471B1 (en) 1999-04-06 2002-05-07 Lipocine, Inc. Compositions and methods for improved delivery of ionizable hydrophobic therapeutic agents
WO2000071079A2 (en) 1999-05-21 2000-11-30 American Bioscience, Inc. Protein stabilized pharmacologically active agents, methods for the preparation thereof and methods for the use thereof
GB9925934D0 (en) * 1999-11-03 1999-12-29 Glaxo Group Ltd Novel apparatus and process
DE60124685T2 (de) 2000-03-23 2007-03-29 Solvay Pharmaceuticals B.V. 4,5-dihydro-1h-pyrazolderivate mit cb1-antagonistischer aktivität
WO2001092293A2 (en) 2000-05-31 2001-12-06 Universiteit Leiden Methods for identifying crystallization conditions for biomolecules
GB0016002D0 (en) * 2000-06-29 2000-08-23 Glaxo Group Ltd Novel process for preparing crystalline particles
GB0016040D0 (en) * 2000-06-29 2000-08-23 Glaxo Group Ltd Novel process for preparing crystalline particles
DK1347747T3 (da) * 2000-12-22 2006-04-10 Baxter Int Fremgangsmåde til behandling af submikropartikelsuspensioner af farmaceutiske midler
US6869617B2 (en) * 2000-12-22 2005-03-22 Baxter International Inc. Microprecipitation method for preparing submicron suspensions
AU2002317409B2 (en) * 2001-08-06 2007-06-21 Astrazeneca Ab Aqueous dispersion comprising stable nanoparticles of a water-insoluble active and an excipient like middle chain triglycerides (MCT)
US20060003012A9 (en) 2001-09-26 2006-01-05 Sean Brynjelsen Preparation of submicron solid particle suspensions by sonication of multiphase systems
GB0125604D0 (en) 2001-10-25 2001-12-19 Glaxo Group Ltd Novel process
SE0104330D0 (sv) 2001-12-19 2001-12-19 Astrazeneca Ab Therapeutic agents
SE0104332D0 (sv) 2001-12-19 2001-12-19 Astrazeneca Ab Therapeutic agents
GB0302673D0 (en) * 2003-02-06 2003-03-12 Astrazeneca Ab Pharmaceutical formulations
GB0302672D0 (en) * 2003-02-06 2003-03-12 Astrazeneca Ab Pharmaceutical formulations
GB0302671D0 (en) * 2003-02-06 2003-03-12 Astrazeneca Ab Pharmaceutical formulations

Also Published As

Publication number Publication date
IL165930A0 (en) 2006-01-15
CN1668280A (zh) 2005-09-14
EP1524964B1 (en) 2010-12-01
DE60335189D1 (de) 2011-01-13
JP2006504511A (ja) 2006-02-09
MXPA05000595A (es) 2005-04-19
CN100594885C (zh) 2010-03-24
CA2492709A1 (en) 2004-01-29
ATE489939T1 (de) 2010-12-15
GB0216700D0 (en) 2002-08-28
ZA200410343B (en) 2005-10-17
NZ537654A (en) 2006-08-31
CA2492709C (en) 2012-01-24
WO2004009057A1 (en) 2004-01-29
AU2003244871A1 (en) 2004-02-09
HK1075199A1 (en) 2005-12-09
KR101061309B1 (ko) 2011-08-31
BR0312631A (pt) 2005-04-19
KR20050023432A (ko) 2005-03-09
EP1524964A1 (en) 2005-04-27
US20050202092A1 (en) 2005-09-15
US7780989B2 (en) 2010-08-24
ES2355137T3 (es) 2011-03-23

Similar Documents

Publication Publication Date Title
NO20050860L (no) Fremgangsmate for fremstilling av krystallinske nanopartikkeldispersjoner
Scharff et al. Structure of C60 fullerene in water: spectroscopic data
Prasad et al. Biosynthesis of CdS nanoparticles: an improved green and rapid procedure
Zhang et al. Biogenic synthesis of gold nanoparticles by yeast Magnusiomyces ingens LH-F1 for catalytic reduction of nitrophenols
Korbekandi et al. Optimization of biological synthesis of silver nanoparticles using Lactobacillus casei subsp. casei
Brant et al. Aggregation and deposition characteristics of fullerene nanoparticles in aqueous systems
Chowdhury et al. Container to characterization: impacts of metal oxide handling, preparation, and solution chemistry on particle stability
Wang et al. Transport of titanium dioxide nanoparticles in saturated porous media under various solution chemistry conditions
DE60220923D1 (de) Wässrige dispersion stabiler nanopartikel eines wasserunlöslichen wirkstoffs und ein hilfsstoff wie mittelkettige triglyceride (mct)
BRPI0719483A8 (pt) processo para produção de nanoparticula sestáveis e monodispersas de prata metálica e pasta de nanoparticulas de prata metálica
Yamazaki et al. Selective adsorption of bilirubin against albumin to oxidized single-wall carbon nanohorns
Kong et al. Facile synthesis of nickel nanowires with controllable morphology
Roto et al. Effect of reducing agents on physical and chemical properties of silver nanoparticles
Chen et al. Synthesis of porous structured ZnO/Ag composite fibers with enhanced photocatalytic performance under visible irradiation
CN109950014A (zh) 一种弱水解体系制备磁性介孔二氧化硅复合微球的方法
Choi et al. γ-ray synthesis and size characterization of CdS quantum dot (QD) particles using flow and sedimentation field-flow fractionation (FFF)
CN101953817B (zh) 一种载油溶性物质的微胶囊及其制备方法
CN108126199B (zh) 一种可降解双响应智能高分子/硫化钼药物载体的制备方法
Gigault et al. Selection of an appropriate aqueous nano-fullerene (nC60) preparation protocol for studying its environmental fate and behavior
CN102416180B (zh) 一种功能集成药物载体及其制备方法
Bai et al. Effects of silica-based nanostructures with raspberry-like morphology and surfactant on the interfacial behavior of light, medium, and heavy crude oils at oil-aqueous interfaces
Wang et al. Influence of polyvinyl pyrrolidone on the dispersion of multi-walled carbon nanotubes in aqueous solution
CN104741618A (zh) 利用棉铃虫核型多角体蛋白提取物制备铂纳米线的方法
CN104001933B (zh) 利用棉铃虫核型多角体蛋白提取物制备金纳米线的方法
Razack et al. A way to create a sustainable environment: Green nanotechnology–with an emphasis on noble metals

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application