NO20044999L - Polymorf av 4-[2-[4-[1-(2-etoksyetyl)-1H-benzimidazol-2-yl]-1-piperidinyl]etyl]-alfa,alfa-dimetyl-benzeneddiksyre - Google Patents

Polymorf av 4-[2-[4-[1-(2-etoksyetyl)-1H-benzimidazol-2-yl]-1-piperidinyl]etyl]-alfa,alfa-dimetyl-benzeneddiksyre

Info

Publication number
NO20044999L
NO20044999L NO20044999A NO20044999A NO20044999L NO 20044999 L NO20044999 L NO 20044999L NO 20044999 A NO20044999 A NO 20044999A NO 20044999 A NO20044999 A NO 20044999A NO 20044999 L NO20044999 L NO 20044999L
Authority
NO
Norway
Prior art keywords
alpha
benzimidazol
polymorph
ethoxyethyl
piperidinyl
Prior art date
Application number
NO20044999A
Other languages
English (en)
Other versions
NO329327B1 (no
Inventor
Aurelio Orjales Venero
Ramon Mosquera Pestana
Victor Rubio Royo
Maravillas Bordell Martin
Gonzalo Canal Mori
Haydee Blanco Fuente
Maria Luisa Lucero De Pablo
Martin Maravillas Bordell
Mori Gonzalo Canal
Fuente Haydc Blanco
De Pablo Maria Luisa Lucero
Original Assignee
Faes Farma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=29225789&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20044999(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Faes Farma Sa filed Critical Faes Farma Sa
Publication of NO20044999L publication Critical patent/NO20044999L/no
Publication of NO329327B1 publication Critical patent/NO329327B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO20044999A 2002-04-19 2004-11-17 Polymorf av 4-[2-[4-[1-(2-etoksyetyl)-1H-benzimidazol-2-yl]-1-piperidinyl]etyl]-¿,¿-dimetyl-benzeneddiksyre, fremgangsmate til fremstilling derav, farmasoytiske preparater som inneholder nevnte polymorf, og anvendelse derav NO329327B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/ES2002/000194 WO2003089425A1 (es) 2002-04-19 2002-04-19 POLIMORFO DEL ÁCIDO 4-[2-[4-[1-(2-ETOXIETIL)-1H-BENCIMIDAZOL-2-IL]-1-PIPERIDINIL]ETIL]-α, α-DIMETIL-BENCENOACÉTICO

Publications (2)

Publication Number Publication Date
NO20044999L true NO20044999L (no) 2005-01-14
NO329327B1 NO329327B1 (no) 2010-09-27

Family

ID=29225789

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20044999A NO329327B1 (no) 2002-04-19 2004-11-17 Polymorf av 4-[2-[4-[1-(2-etoksyetyl)-1H-benzimidazol-2-yl]-1-piperidinyl]etyl]-¿,¿-dimetyl-benzeneddiksyre, fremgangsmate til fremstilling derav, farmasoytiske preparater som inneholder nevnte polymorf, og anvendelse derav

Country Status (31)

Country Link
US (2) US7612095B2 (no)
EP (1) EP1505066B1 (no)
JP (1) JP5142448B2 (no)
KR (1) KR100673140B1 (no)
CN (1) CN1290843C (no)
AR (1) AR039423A1 (no)
AT (1) ATE347550T1 (no)
AU (1) AU2002255017B2 (no)
BG (1) BG66302B1 (no)
BR (1) BRPI0215703B8 (no)
CA (1) CA2484460C (no)
CY (2) CY1107564T1 (no)
CZ (1) CZ305162B6 (no)
DE (1) DE60216641T2 (no)
DK (1) DK1505066T3 (no)
ES (1) ES2278018T3 (no)
HK (1) HK1072772A1 (no)
HR (1) HRP20041048B1 (no)
HU (1) HU230032B1 (no)
IL (1) IL164645A (no)
MX (1) MXPA04010313A (no)
NO (1) NO329327B1 (no)
NZ (1) NZ536551A (no)
PA (1) PA8571201A1 (no)
PE (1) PE20040086A1 (no)
PT (1) PT1505066E (no)
SI (1) SI1505066T1 (no)
SK (1) SK288052B6 (no)
UA (1) UA76866C2 (no)
UY (1) UY27762A1 (no)
WO (1) WO2003089425A1 (no)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010013472A (ja) * 2009-09-09 2010-01-21 Faes Farma Sa ４−［２−［１−（２−エトキシエチル）−１Ｈ−ベンズイミダゾール−２−イル］−１−ピペリジニル］エチル］−α，α−ジメチルベンゼノ酢酸の多形体
WO2013001731A1 (ja) * 2011-06-30 2013-01-03 パナソニック株式会社 通信システム、ユーザ端末並びに通信装置
CN102675101B (zh) * 2012-05-16 2014-01-29 王蕾 2-(4-卤乙基)苯基-2-甲基丙酸酯的制备方法及合成比拉斯汀的方法
CZ307500B6 (cs) 2012-08-15 2018-10-24 Zentiva, K.S. Způsob přípravy derivátu 2-methyl-2´-fenylpropionové kyseliny využívající nové intermediáty
CN103214454A (zh) * 2013-03-30 2013-07-24 北京万全德众医药生物技术有限公司 一种比拉斯汀晶型及制备方法
WO2014188453A2 (en) * 2013-05-24 2014-11-27 Msn Laboratories Private Limited Novel process for the preparation of 2-[4-(2-{4-[1-(2-ethoxyethyl)-1h-benzimidazol-2-yl]-1-piperidinyl}ethyl) phenyl]-2-methylpropanoic acid
CN103356616A (zh) * 2013-06-29 2013-10-23 北京万全德众医药生物技术有限公司 一种含有比拉斯汀的药物组合物及其制备方法
CN104447682A (zh) * 2013-09-12 2015-03-25 天津市汉康医药生物技术有限公司 比拉斯汀化合物
CN104398481A (zh) * 2014-10-29 2015-03-11 万全万特制药江苏有限公司 比拉斯汀口崩片及其制备方法
CA2993134A1 (en) * 2015-07-24 2017-02-02 Urquima, S.A. Crystalline forms of bilastine and preparation methods thereof
EP3170816A1 (en) * 2015-11-20 2017-05-24 Faes Farma, S.A. Supersaturated compositions of benzimidazole compounds
EP3170817A1 (en) * 2015-11-20 2017-05-24 Faes Farma, S.A. Co-crystals of benzimidazole compounds
WO2017167949A1 (en) 2016-04-01 2017-10-05 Krka, D.D., Novo Mesto Crystalline forms of bilastine
EP3452462A4 (en) * 2016-05-05 2019-10-23 MSN Laboratories Private Limited, R&D Center SOLID STATE FORMS OF 2- [4- (2- {4- [1- (2-ETHOXYETHYL) -1H-BENZIMIDAZOL-2-YL] -1-PIPERIDINYL} ETHYL) PHENYL] -2-METHYLPROPANOIC ACID AND PREPARATION METHOD THEREOF
EP3453384B1 (en) 2017-09-07 2020-05-27 Alfred E. Tiefenbacher (GmbH & Co. KG) Pharmaceutical tablet composition comprising bilastine
PL3641735T3 (pl) 2017-12-18 2021-09-06 Alfred E. Tiefenbacher (Gmbh & Co. Kg) Kompozycja farmaceutyczna tabletki zawierająca bilastynę w postaci 3 i rozpuszczalny w wodzie wypełniacz
EP3470062B1 (en) 2017-12-18 2020-10-28 Alfred E. Tiefenbacher (GmbH & Co. KG) Pharmaceutical tablet composition comprising bilastine polymorphic form 3 and magnesium aluminometasilicate
CN111727035B (zh) 2018-01-18 2024-05-28 费斯制药股份有限公司 包含比拉斯汀、β-环糊精和至少一种胶凝剂的眼用组合物
WO2022135863A1 (en) 2020-12-23 2022-06-30 Biohorm, S.L. A non-micronized bilastine composition

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4810789A (en) * 1987-08-28 1989-03-07 Bristol-Myers Company Process for buspirone hydrochloride polymorphic crystalline form conversion
ES2124167B1 (es) * 1996-06-04 1999-09-16 Espanola Prod Quimicos Nuevos derivados del bencimidazol con actividad antihistaminica.
RU2001130883A (ru) * 1999-04-16 2004-03-20 Др. Редди`З Лабораториз Лимитед (In) Новые полиморфные формы антидиабетического средства, способ их получения и содержащие их фармацевтические композиции
EP1173435B1 (en) * 1999-04-23 2003-07-30 SmithKline Beecham plc Polymorph of 5-[4-[2-(n-methyl-n-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione maleic acid salt

Also Published As

Publication number Publication date
CN1290843C (zh) 2006-12-20
UA76866C2 (uk) 2006-09-15
CY2013015I1 (el) 2015-08-05
US7612095B2 (en) 2009-11-03
CY1107564T1 (el) 2013-03-13
BRPI0215703B1 (pt) 2017-06-27
CA2484460C (en) 2009-09-29
JP5142448B2 (ja) 2013-02-13
CZ20041122A3 (cs) 2005-03-16
MXPA04010313A (es) 2005-06-08
IL164645A0 (en) 2005-12-18
HRP20041048A2 (en) 2005-02-28
DK1505066T3 (da) 2007-03-19
SK50202004A3 (sk) 2005-05-05
UY27762A1 (es) 2003-09-30
CA2484460A1 (en) 2003-10-30
US20050203141A1 (en) 2005-09-15
ES2278018T3 (es) 2007-08-01
AU2002255017A1 (en) 2003-11-03
BRPI0215703B8 (pt) 2021-05-25
DE60216641D1 (de) 2007-01-18
PT1505066E (pt) 2007-03-30
AU2002255017B2 (en) 2008-11-13
CN1628112A (zh) 2005-06-15
ATE347550T1 (de) 2006-12-15
BR0215703A (pt) 2005-02-01
NO329327B1 (no) 2010-09-27
KR100673140B1 (ko) 2007-01-22
HRP20041048A9 (hr) 2013-01-31
HU230032B1 (hu) 2015-05-28
BG66302B1 (bg) 2013-03-29
PA8571201A1 (es) 2003-12-10
WO2003089425A1 (es) 2003-10-30
EP1505066A1 (en) 2005-02-09
NZ536551A (en) 2006-08-31
HRP20041048B1 (hr) 2013-04-30
CY2013015I2 (el) 2015-08-05
IL164645A (en) 2010-11-30
EP1505066B1 (en) 2006-12-06
HK1072772A1 (en) 2005-09-09
US20100004285A1 (en) 2010-01-07
BG108941A (en) 2005-12-30
KR20050005448A (ko) 2005-01-13
SK288052B6 (sk) 2013-03-01
CZ305162B6 (cs) 2015-05-27
SI1505066T1 (sl) 2007-04-30
HUP0500241A2 (hu) 2005-06-28
PE20040086A1 (es) 2004-04-27
DE60216641T2 (de) 2007-09-27
AR039423A1 (es) 2005-02-16
JP2005529120A (ja) 2005-09-29

Similar Documents

Publication Publication Date Title
NO20044999L (no) Polymorf av 4-[2-[4-[1-(2-etoksyetyl)-1H-benzimidazol-2-yl]-1-piperidinyl]etyl]-alfa,alfa-dimetyl-benzeneddiksyre
NO20061420L (no) 3-[(2-{4-Heksyloksykarbonylamino-Imino-metyl)-Fenylamino]-Metyl}-1-Metyl-1H-Benzimidazol-5-Karbonyl)-Pyridin-2-yl-Amino]-Propansyre Etylester Metansulfonat og
SI1870100T1 (sl) Metansulfonat etil estra heksiloksikarbonilamino imino metil fenilamino metil metil H benzimidazol karbonil piridin il amino propionske kisline
NO2017035I1 (no) Nintedanib, 3-Z-{1-(4-(N-((4-metyl-piperazin-1-y-metylkarbonyl)-N-metyl-amino)-anilino)-1-fenylmetylenj- 6-metoksykarbonyl-2-indolinon
EP1828143A4 (en) 1H-PHENANTHRO [9,10-D] IMIDAZOLES SUBSTITUTED INTO 2 BY PHENYL OR HETEROCYCLE AS INHIBITORS OF MPGES-1
EP1954683A4 (en) 2- (PHENYL OR HETEROCYCLIC) -1H-PHENANTRHO (9,10-D) IMIDAZOLES AS INHIBITORS OF MPGES-1
ATE433968T1 (de) Imidazolverbindungen als inhibitoren des transformierenden wachstumsfaktors (twf)
EP3045175B8 (en) Polymorphic forms of 3-(4-amino-1-oxo-1,3 dihydroisoindol-2-yl)-piperidine-2,6-dione
ZA200407985B (en) 1-(4-Piperidinyl) benzimidazolones as histamine H3antagonists.
ATE504567T1 (de) 1-heterocyclylsulfonyl, 2-aminomethyl, 5- (hetero-) aryl-substitutierte 1-h-pyrrolderivate als säuresekretionshemmer
DE60330227D1 (de) N3-alkylierte benzimidazol-derivate als mek-hemmer
ATE307128T1 (de) 3-(4-amidopyrrol-2-ylmethylidene)-2-indolinon- derivative als protein-kinase inhibitoren
DE60319813D1 (de) 1-(4-piperidinyl)benzimidazole als histamin h3 antagonisten
IL192024A0 (en) 3,5-substituted piperidine compounds as renin inhibitors
NO20050676L (no) Krystallinsk 2,5-dion-3-(1-metyl-lH-indol-3-yl)-4-[1-(pyridin-2-ylmetyl)piperidin-4-yl]-1H-indol-3-yl]-IH-pyrrol monohydroklorid.
IL178031A0 (en) [4-(5-aminomethyl-2-fluoro-phenyl)-piperidin-1-yl]-(4-bromo-3-methyl-5-propoxy-thiophen-2-yl)-methanone hydrochloride as an inhibitor of mast cell tryptase
IL174926A0 (en) Crystalline forms of {2-[1-(3,5-bis-trifluoromethylbenzyl)-5-pyridin-4-yl-1h-[1,2,3]triazol-4-yl]-pyridin-3-yl}-(-2-chlorophenyl)-methanone
IL184885A0 (en) 7-{4-[2-(2,6-dihydro-4-methylphenoxy)ethoxyl]phenyl}-3,9-diazabicyclo[3.3.31]non-6-ene-s-carboxylic acid cyclopropyl-(2,3-dimethylbenzyd amide as inhibitors of renin for the treatment of hypertension
ATE491692T1 (de) 1-(imidazolin-2-yl)amino-1,2-diphenylethan- verbindungen zur bekämpfung von tierpestkrankheiten
IL180336A0 (en) Crystal forms of (3r) -1 - (2 - methylalanyl - d - tryptophyl) - 3 -(phenylmethyl)-3- piperidinecarboxylic acid 1, 2, 2 - trimethylhydrazide
NL1025709A1 (nl) 3-(1-[3-(1,3-Benzothiazol-6-yI)propylcarbamoyl]cycloalkyI)propaanzuurderivaten Derivatives als NEP-remmers.
NO20043457L (no) 3-(imidazolyl)-2-alkoksypropansyrer som TAFIA inhibitorer
DE60319836D1 (de) Heterocyclische kondensierte pyrazolderivate als kinaseinhibitoren
NO20043400L (no) Fremgangsmater for nukleinsyreamplifisering
ZA200804956B (en) 3,5-substituted piperidine compounds as renin inhibitors

Legal Events

Date Code Title Description
MK1K Patent expired