NO20012489L - Antagonistiske analoger av GH-RH-inhiberende IGF-I og II - Google Patents

Antagonistiske analoger av GH-RH-inhiberende IGF-I og II

Info

Publication number
NO20012489L
NO20012489L NO20012489A NO20012489A NO20012489L NO 20012489 L NO20012489 L NO 20012489L NO 20012489 A NO20012489 A NO 20012489A NO 20012489 A NO20012489 A NO 20012489A NO 20012489 L NO20012489 L NO 20012489L
Authority
NO
Norway
Prior art keywords
inhibiting igf
antagonistic analogs
antagonistic
analogs
igf
Prior art date
Application number
NO20012489A
Other languages
English (en)
Other versions
NO20012489D0 (no
Inventor
Andrew V Schally
Jozsef Varga
Marta Zarandi
Original Assignee
Univ Tulane
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Tulane filed Critical Univ Tulane
Publication of NO20012489D0 publication Critical patent/NO20012489D0/no
Publication of NO20012489L publication Critical patent/NO20012489L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/60Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/02Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • A61P5/04Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin for decreasing, blocking or antagonising the activity of the hypothalamic hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/06Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/06Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • A61P5/08Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH for decreasing, blocking or antagonising the activity of the anterior pituitary hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
NO20012489A 1998-11-25 2001-05-21 Antagonistiske analoger av GH-RH-inhiberende IGF-I og II NO20012489L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/199,381 US6057422A (en) 1998-11-25 1998-11-25 Antagonistic analogs of GH-RH inhibiting IGF-I and -II
PCT/US1999/027822 WO2000031136A1 (en) 1998-11-25 1999-11-23 Antagonistic analogs of gh-rh inhibiting igf-i and -ii

Publications (2)

Publication Number Publication Date
NO20012489D0 NO20012489D0 (no) 2001-05-21
NO20012489L true NO20012489L (no) 2001-07-04

Family

ID=22737273

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20012489A NO20012489L (no) 1998-11-25 2001-05-21 Antagonistiske analoger av GH-RH-inhiberende IGF-I og II

Country Status (29)

Country Link
US (2) US6057422A (no)
EP (1) EP1133522B1 (no)
JP (1) JP2002530432A (no)
KR (1) KR100629013B1 (no)
CN (1) CN100422211C (no)
AR (1) AR022392A1 (no)
AT (1) ATE332310T1 (no)
AU (1) AU757222B2 (no)
BG (1) BG65137B1 (no)
BR (1) BR9915512A (no)
CA (1) CA2351665C (no)
CO (1) CO5180565A1 (no)
CZ (1) CZ20011794A3 (no)
DE (1) DE69932255T2 (no)
DK (1) DK1133522T3 (no)
ES (1) ES2264279T3 (no)
HK (1) HK1036461A1 (no)
HU (1) HUP0105094A3 (no)
IL (1) IL142899A0 (no)
NO (1) NO20012489L (no)
NZ (1) NZ511307A (no)
PL (1) PL197471B1 (no)
PT (1) PT1133522E (no)
RU (1) RU2235099C2 (no)
SK (1) SK7252001A3 (no)
TR (1) TR200101492T2 (no)
TW (1) TW585873B (no)
UA (1) UA68407C2 (no)
WO (1) WO2000031136A1 (no)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060121041A1 (en) * 2001-07-12 2006-06-08 Lori Friedman Gpcs as modifiers of the irrtk p21 pathways and methods of use
US20040121407A1 (en) * 2002-09-06 2004-06-24 Elixir Pharmaceuticals, Inc. Regulation of the growth hormone/IGF-1 axis
JP2006504694A (ja) * 2002-09-18 2006-02-09 サントル・オスピタリエ・ドゥ・リュニヴェルシテ・ドゥ・モントリオール・(シー・エイチ・ユー・エム) Ghrh類似体
TW200517400A (en) * 2003-08-05 2005-06-01 Univ Tulane Antagonistic analogs of GH-RH (2003)
US8691942B2 (en) 2008-03-28 2014-04-08 University Of Miami N- and C- terminal substituted antagonistic analogs of GH-RH
MX2010010642A (es) * 2008-03-28 2011-03-29 The Univ Of Miami Nuevos analogos antagonistas, sustituidos, n- y c- terminales, de hormona liberadora de hormona de crecimiento (gh-rh).
EP2310029B1 (en) 2008-06-12 2019-04-03 Ipsen Bioinnovation Limited Fusion proteins for use in the treatment of cancer
CN102112145B (zh) 2008-06-12 2014-07-30 辛它可辛有限公司 神经内分泌病的抑制
GB0820970D0 (en) 2008-11-17 2008-12-24 Syntaxin Ltd Suppression of cancer
US8227421B2 (en) 2009-09-17 2012-07-24 University Of Miami Fluorinated GHRH antagonists
JP6113144B2 (ja) 2011-04-21 2017-04-12 セラテクノロジーズ・インコーポレーテッド 成長ホルモン放出因子(grf)類似体およびその使用
US9079974B2 (en) * 2011-12-21 2015-07-14 The University Of Miami GH-RH analogs with potent agonistic effects
US9855312B2 (en) 2012-12-21 2018-01-02 University Of Miami GHRH agonists for the treatment of ischemic disorders
EP2935317B1 (en) 2012-12-21 2019-03-27 University of Miami Ghrh agonists for islet cell transplantation and function and the treatment of diabetes
AU2015346277B2 (en) 2014-11-12 2020-03-26 Centre Hospitalier Universitaire De Liège Treatment of hormonal disorders of growth
WO2020163833A2 (en) 2019-02-08 2020-08-13 United States Government As Represented By The Department Of Veterans Affairs Growth hormone-releasing hormone antagonists and uses thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4659693A (en) * 1984-04-30 1987-04-21 Syntex (U.S.A.) Inc. N,N'-dialkyl substituted guanidino amino acyl residue substituted GRF-analog peptides
CA2082059A1 (en) * 1990-05-04 1991-11-05 David H. Coy Synthetic grf analogs
US5550212A (en) * 1993-12-17 1996-08-27 The Administrators Of The Tulane Educational Fund Analogues of hGH-RH(1-29)NH2 having antagonistic activity
US5942489A (en) * 1996-05-03 1999-08-24 The Administrators Of The Tulane Educational Fund HGH-RH(1-29)NH2 analogues having antagonistic activity

Also Published As

Publication number Publication date
AR022392A1 (es) 2002-09-04
BG65137B1 (bg) 2007-03-30
ATE332310T1 (de) 2006-07-15
BG105638A (en) 2002-01-31
PL349877A1 (en) 2002-09-23
HUP0105094A2 (hu) 2002-04-29
RU2235099C2 (ru) 2004-08-27
BR9915512A (pt) 2001-08-07
CO5180565A1 (es) 2002-07-30
CN1328570A (zh) 2001-12-26
DE69932255T2 (de) 2007-05-31
UA68407C2 (en) 2004-08-16
AU757222B2 (en) 2003-02-06
EP1133522A1 (en) 2001-09-19
SK7252001A3 (en) 2002-02-05
CN100422211C (zh) 2008-10-01
PT1133522E (pt) 2006-11-30
DE69932255D1 (de) 2006-08-17
NO20012489D0 (no) 2001-05-21
NZ511307A (en) 2005-01-28
HK1036461A1 (en) 2002-01-04
EP1133522B1 (en) 2006-07-05
US7026281B1 (en) 2006-04-11
CZ20011794A3 (cs) 2002-02-13
KR20010101079A (ko) 2001-11-14
TW585873B (en) 2004-05-01
DK1133522T3 (da) 2006-11-06
WO2000031136A9 (en) 2001-07-19
US6057422A (en) 2000-05-02
WO2000031136A1 (en) 2000-06-02
TR200101492T2 (tr) 2001-11-21
JP2002530432A (ja) 2002-09-17
CA2351665A1 (en) 2000-06-02
PL197471B1 (pl) 2008-04-30
KR100629013B1 (ko) 2006-09-26
AU2029100A (en) 2000-06-13
CA2351665C (en) 2008-09-02
HUP0105094A3 (en) 2002-05-28
ES2264279T3 (es) 2006-12-16
IL142899A0 (en) 2002-04-21

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Legal Events

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