HK1036461A1 - Antagonistic analogs of gh-rh inhibiting igf-i and-ii - Google Patents
Antagonistic analogs of gh-rh inhibiting igf-i and-iiInfo
- Publication number
- HK1036461A1 HK1036461A1 HK01107515A HK01107515A HK1036461A1 HK 1036461 A1 HK1036461 A1 HK 1036461A1 HK 01107515 A HK01107515 A HK 01107515A HK 01107515 A HK01107515 A HK 01107515A HK 1036461 A1 HK1036461 A1 HK 1036461A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- inhibiting igf
- antagonistic analogs
- antagonistic
- analogs
- igf
- Prior art date
Links
- 230000003042 antagnostic effect Effects 0.000 title 1
- 230000002401 inhibitory effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/60—Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
- A61P5/04—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin for decreasing, blocking or antagonising the activity of the hypothalamic hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
- A61P5/08—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH for decreasing, blocking or antagonising the activity of the anterior pituitary hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Endocrinology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/199,381 US6057422A (en) | 1998-11-25 | 1998-11-25 | Antagonistic analogs of GH-RH inhibiting IGF-I and -II |
| PCT/US1999/027822 WO2000031136A1 (en) | 1998-11-25 | 1999-11-23 | Antagonistic analogs of gh-rh inhibiting igf-i and -ii |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1036461A1 true HK1036461A1 (en) | 2002-01-04 |
Family
ID=22737273
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK01107515A HK1036461A1 (en) | 1998-11-25 | 2001-10-29 | Antagonistic analogs of gh-rh inhibiting igf-i and-ii |
Country Status (29)
| Country | Link |
|---|---|
| US (2) | US6057422A (no) |
| EP (1) | EP1133522B1 (no) |
| JP (1) | JP2002530432A (no) |
| KR (1) | KR100629013B1 (no) |
| CN (1) | CN100422211C (no) |
| AR (1) | AR022392A1 (no) |
| AT (1) | ATE332310T1 (no) |
| AU (1) | AU757222B2 (no) |
| BG (1) | BG65137B1 (no) |
| BR (1) | BR9915512A (no) |
| CA (1) | CA2351665C (no) |
| CO (1) | CO5180565A1 (no) |
| CZ (1) | CZ20011794A3 (no) |
| DE (1) | DE69932255T2 (no) |
| DK (1) | DK1133522T3 (no) |
| ES (1) | ES2264279T3 (no) |
| HK (1) | HK1036461A1 (no) |
| HU (1) | HUP0105094A3 (no) |
| IL (1) | IL142899A0 (no) |
| NO (1) | NO20012489L (no) |
| NZ (1) | NZ511307A (no) |
| PL (1) | PL197471B1 (no) |
| PT (1) | PT1133522E (no) |
| RU (1) | RU2235099C2 (no) |
| SK (1) | SK7252001A3 (no) |
| TR (1) | TR200101492T2 (no) |
| TW (1) | TW585873B (no) |
| UA (1) | UA68407C2 (no) |
| WO (1) | WO2000031136A1 (no) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2454135A1 (en) * | 2001-07-12 | 2003-01-23 | Exelixis, Inc. | Gpcs as modifiers of the irrtk and p21 pathways and methods of use |
| US20040121407A1 (en) * | 2002-09-06 | 2004-06-24 | Elixir Pharmaceuticals, Inc. | Regulation of the growth hormone/IGF-1 axis |
| CN1688696A (zh) * | 2002-09-18 | 2005-10-26 | 蒙特利尔大学医疗中心 | Ghrh类似物 |
| TW200517400A (en) * | 2003-08-05 | 2005-06-01 | Univ Tulane | Antagonistic analogs of GH-RH (2003) |
| BRPI0910873A2 (pt) * | 2008-03-28 | 2015-10-06 | Us Of America Represented By The Dept Of Veterans Affairs | análogos antagonistas de gh-rh substituídos nos terminais n e c |
| US8691942B2 (en) | 2008-03-28 | 2014-04-08 | University Of Miami | N- and C- terminal substituted antagonistic analogs of GH-RH |
| JP5728380B2 (ja) | 2008-06-12 | 2015-06-03 | シンタクシン リミテッドＳｙｎｔａｘｉｎ Ｌｉｍｉｔｅｄ | 神経内分泌疾患の抑制 |
| EP3473643A1 (en) | 2008-06-12 | 2019-04-24 | Ipsen Bioinnovation Limited | Fusion proteins for use in the treatemnt of cancer |
| GB0820970D0 (en) | 2008-11-17 | 2008-12-24 | Syntaxin Ltd | Suppression of cancer |
| US8227421B2 (en) * | 2009-09-17 | 2012-07-24 | University Of Miami | Fluorinated GHRH antagonists |
| EP2699591A4 (en) | 2011-04-21 | 2014-05-07 | Theratechnologies Inc | ANALOGS OF THE GROWTH HORMONE-RELATED FACTOR (GRF) AND USES THEREOF |
| US9079974B2 (en) * | 2011-12-21 | 2015-07-14 | The University Of Miami | GH-RH analogs with potent agonistic effects |
| EP2934565B1 (en) | 2012-12-21 | 2019-03-13 | University of Miami | Ghrh agonists for the treatment of ischemic disorders |
| WO2014100816A2 (en) | 2012-12-21 | 2014-06-26 | University Of Miami | Ghrh agonists for islet cell transplantation and function and the treatment of diabetes |
| AU2015346277B2 (en) | 2014-11-12 | 2020-03-26 | Centre Hospitalier Universitaire De Liège | Treatment of hormonal disorders of growth |
| AU2020218272A1 (en) | 2019-02-08 | 2021-09-02 | United States Government As Represented By The Department Of Veterans Affairs | Growth hormone-releasing hormone antagonists and uses thereof |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4659693A (en) * | 1984-04-30 | 1987-04-21 | Syntex (U.S.A.) Inc. | N,N'-dialkyl substituted guanidino amino acyl residue substituted GRF-analog peptides |
| AU651976B2 (en) * | 1990-05-04 | 1994-08-11 | The Administrators Of The Tulane Eductional Fund | Novel synthetic GRF analogs |
| US5550212A (en) * | 1993-12-17 | 1996-08-27 | The Administrators Of The Tulane Educational Fund | Analogues of hGH-RH(1-29)NH2 having antagonistic activity |
| US5942489A (en) * | 1996-05-03 | 1999-08-24 | The Administrators Of The Tulane Educational Fund | HGH-RH(1-29)NH2 analogues having antagonistic activity |
-
1998
- 1998-11-25 US US09/199,381 patent/US6057422A/en not_active Expired - Fee Related
-
1999
- 1999-11-16 CO CO99072002A patent/CO5180565A1/es not_active Application Discontinuation
- 1999-11-23 IL IL14289999A patent/IL142899A0/xx not_active IP Right Cessation
- 1999-11-23 CZ CZ20011794A patent/CZ20011794A3/cs unknown
- 1999-11-23 JP JP2000583962A patent/JP2002530432A/ja not_active Ceased
- 1999-11-23 DE DE69932255T patent/DE69932255T2/de not_active Expired - Fee Related
- 1999-11-23 NZ NZ511307A patent/NZ511307A/en unknown
- 1999-11-23 ES ES99963962T patent/ES2264279T3/es not_active Expired - Lifetime
- 1999-11-23 PL PL349877A patent/PL197471B1/pl unknown
- 1999-11-23 DK DK99963962T patent/DK1133522T3/da active
- 1999-11-23 SK SK725-2001A patent/SK7252001A3/sk unknown
- 1999-11-23 AT AT99963962T patent/ATE332310T1/de not_active IP Right Cessation
- 1999-11-23 TR TR2001/01492T patent/TR200101492T2/xx unknown
- 1999-11-23 EP EP99963962A patent/EP1133522B1/en not_active Expired - Lifetime
- 1999-11-23 AU AU20291/00A patent/AU757222B2/en not_active Ceased
- 1999-11-23 PT PT99963962T patent/PT1133522E/pt unknown
- 1999-11-23 CN CNB998137359A patent/CN100422211C/zh not_active Expired - Fee Related
- 1999-11-23 BR BR9915512-5A patent/BR9915512A/pt not_active Application Discontinuation
- 1999-11-23 RU RU2001117218/04A patent/RU2235099C2/ru not_active IP Right Cessation
- 1999-11-23 HU HU0105094A patent/HUP0105094A3/hu unknown
- 1999-11-23 UA UA2001064393A patent/UA68407C2/uk unknown
- 1999-11-23 WO PCT/US1999/027822 patent/WO2000031136A1/en active IP Right Grant
- 1999-11-23 KR KR1020017006568A patent/KR100629013B1/ko not_active IP Right Cessation
- 1999-11-23 CA CA002351665A patent/CA2351665C/en not_active Expired - Fee Related
- 1999-11-24 TW TW088120503A patent/TW585873B/zh not_active IP Right Cessation
- 1999-11-24 AR ARP990105977A patent/AR022392A1/es active IP Right Grant
-
2000
- 2000-04-11 US US09/547,215 patent/US7026281B1/en not_active Expired - Fee Related
-
2001
- 2001-05-21 NO NO20012489A patent/NO20012489L/no not_active Application Discontinuation
- 2001-06-22 BG BG105638A patent/BG65137B1/bg unknown
- 2001-10-29 HK HK01107515A patent/HK1036461A1/xx not_active IP Right Cessation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20091123 |