SI0948541T1 - PTHrP analogi - Google Patents

PTHrP analogi

Info

Publication number
SI0948541T1
SI0948541T1 SI9730730T SI9730730T SI0948541T1 SI 0948541 T1 SI0948541 T1 SI 0948541T1 SI 9730730 T SI9730730 T SI 9730730T SI 9730730 T SI9730730 T SI 9730730T SI 0948541 T1 SI0948541 T1 SI 0948541T1
Authority
SI
Slovenia
Prior art keywords
pthrp
analogs
Prior art date
Application number
SI9730730T
Other languages
English (en)
Inventor
Zheng Xin Dong
Original Assignee
Sod Conseils Rech Applic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/779,768 external-priority patent/US5969095A/en
Application filed by Sod Conseils Rech Applic filed Critical Sod Conseils Rech Applic
Publication of SI0948541T1 publication Critical patent/SI0948541T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/635—Parathyroid hormone (parathormone); Parathyroid hormone-related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
SI9730730T 1997-01-07 1997-12-08 PTHrP analogi SI0948541T1 (sl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US08/779,768 US5969095A (en) 1995-07-13 1997-01-07 Analogs of parathyroid hormone
US08/813,534 US5955574A (en) 1995-07-13 1997-03-07 Analogs of parathyroid hormone
EP97951595A EP0948541B1 (en) 1997-01-07 1997-12-08 Analogs of PTHrP
PCT/US1997/022498 WO1998030590A2 (en) 1997-01-07 1997-12-08 Analogs of parathyroid hormone

Publications (1)

Publication Number Publication Date
SI0948541T1 true SI0948541T1 (sl) 2006-06-30

Family

ID=27119618

Family Applications (2)

Application Number Title Priority Date Filing Date
SI9730730T SI0948541T1 (sl) 1997-01-07 1997-12-08 PTHrP analogi
SI9730795T SI1645566T1 (sl) 1997-01-07 1997-12-08 Analogi paratioridnega hormona

Family Applications After (1)

Application Number Title Priority Date Filing Date
SI9730795T SI1645566T1 (sl) 1997-01-07 1997-12-08 Analogi paratioridnega hormona

Country Status (24)

Country Link
US (1) US5955574A (sl)
EP (3) EP1645566B1 (sl)
JP (1) JP3963482B2 (sl)
KR (2) KR100497709B1 (sl)
CN (1) CN1137898C (sl)
AR (3) AR011517A1 (sl)
AT (2) ATE471342T1 (sl)
AU (1) AU741584B2 (sl)
BR (1) BR9714200A (sl)
CA (1) CA2276614C (sl)
CZ (2) CZ298937B6 (sl)
DE (2) DE69739912D1 (sl)
DK (2) DK0948541T3 (sl)
ES (2) ES2258286T3 (sl)
HK (1) HK1026215A1 (sl)
HU (1) HUP9904596A3 (sl)
IL (1) IL130794A0 (sl)
NO (1) NO993341L (sl)
NZ (1) NZ336610A (sl)
PL (1) PL191898B1 (sl)
PT (2) PT1645566E (sl)
RU (1) RU2198182C2 (sl)
SI (2) SI0948541T1 (sl)
WO (1) WO1998030590A2 (sl)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
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US7410948B2 (en) * 1995-07-13 2008-08-12 Societe De Conseils De Recherches Et D'applications Scientifiques, Sas Analogs of parathyroid hormone
US6544949B1 (en) 1995-07-13 2003-04-08 Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S. Analogs of parathyroid hormone
HU226866B1 (en) * 1997-09-09 2009-12-28 Hoffmann La Roche Fracture healing using pthrp analogs
WO1999057139A2 (en) * 1998-05-05 1999-11-11 Societe De Conseils De Recherches Et D'applications Scientifiques Sas Pth2 receptor selective compounds
CZ2001253A3 (cs) * 1998-07-20 2001-11-14 Societe De Conseils De Recherches Et D'application Peptidové analogy PACAP
US6660843B1 (en) † 1998-10-23 2003-12-09 Amgen Inc. Modified peptides as therapeutic agents
US6489297B1 (en) 2000-02-18 2002-12-03 Dabur Research Foundation Vasoactive intestinal peptide analogs
US20050124537A1 (en) * 2000-04-27 2005-06-09 Amgen Inc. Modulators of receptors for parathyroid hormone and parathyroid hormone-related protein
US6756480B2 (en) 2000-04-27 2004-06-29 Amgen Inc. Modulators of receptors for parathyroid hormone and parathyroid hormone-related protein
KR101320817B1 (ko) 2001-06-01 2013-10-21 노파르티스 아게 부갑상선 호르몬 및 칼시토닌의 경구 투여
WO2003009804A2 (en) 2001-07-23 2003-02-06 The General Hospital Corporation Conformationally constrained parathyroid hormone (pth) analogs
WO2005016265A2 (en) * 2003-08-06 2005-02-24 Rhodia Inc. Method for promoting bone growth
CA2628945A1 (en) 2005-11-10 2007-05-24 Board Of Control Of Michigan Technological University Black bear parathyroid hormone and methods of using black bear parathyroid hormone
US7803770B2 (en) * 2006-10-03 2010-09-28 Radius Health, Inc. Method of treating osteoporosis comprising administration of PTHrP analog
USRE49444E1 (en) 2006-10-03 2023-03-07 Radius Health, Inc. Method of treating osteoporosis comprising administration of PTHrP analog
CN102274492B (zh) * 2006-10-03 2014-11-26 半径健康公司 骨合成代谢蛋白质的药物递送方法
PL2084183T3 (pl) * 2006-10-13 2010-10-29 Lilly Co Eli Pegylowane pth jako modulatory receptora pth i ich zastosowania
US8568737B2 (en) 2007-08-01 2013-10-29 The General Hospital Corporation Screening methods using G-protein coupled receptors and related compositions
EP2411038B1 (en) 2009-03-27 2016-12-28 Van Andel Research Institute Parathyroid hormone peptides and parathyroid hormone-related protein peptides and methods of use
AU2009356227A1 (en) 2009-12-07 2012-06-21 Michigan Technological University Black bear parathyroid hormone and methods of using black bear parathyroid hormone
US20130053448A1 (en) 2010-05-12 2013-02-28 Louis O'Dea Therapeutic Regimens
US9492508B2 (en) 2010-05-13 2016-11-15 The General Hospital Corporation Parathyroid hormone analogs and uses thereof
US9133182B2 (en) 2010-09-28 2015-09-15 Radius Health, Inc. Selective androgen receptor modulators
EP4039253A1 (en) 2015-04-29 2022-08-10 Radius Pharmaceuticals, Inc. Methods of treating cancer
WO2017007777A2 (en) * 2015-07-06 2017-01-12 Zhengxin Dong NOVEL FORMULATIONS OF PTHrP ANALOGUE
WO2017223115A1 (en) 2016-06-22 2017-12-28 Radius Health, Inc. Ar+ breast cancer treatment methods
EP3565542B1 (en) 2017-01-05 2024-04-10 Radius Pharmaceuticals, Inc. Polymorphic forms of rad1901-2hcl
US10996208B2 (en) 2017-04-28 2021-05-04 Radius Health, Inc. Abaloparatide formulations and methods of testing, storing, modifying, and using same
JP7473486B2 (ja) 2018-07-04 2024-04-23 ラジウス ファーマシューティカルズ，インコーポレイテッド Ｒａｄ１９０１－２ｈｃｌの多形形態

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US3773919A (en) 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
IE52535B1 (en) 1981-02-16 1987-12-09 Ici Plc Continuous release pharmaceutical compositions
FR2550204B1 (fr) * 1983-08-05 1987-11-13 Toyo Jozo Kk Derives peptidiques de (nle8,nle1b, tyr34)-h-pth
EP0293158A3 (en) * 1987-05-26 1990-05-09 Merck & Co. Inc. Parathyroid hormone antagonists
WO1990010067A1 (de) * 1989-02-23 1990-09-07 GESELLSCHAFT FüR BIOTECHNOLOGISCHE FORSCHUNG MBH (GBF) Pth-varianten kodierende dna-sequenzen, pth-varianten, expressionsvektor, bakterieller wirt, verwendung und therapeutische zusammensetzung
CA2040264A1 (en) * 1990-04-12 1991-10-13 Tatsuhiko Kanmera Parathyroid hormone antagonists
JPH0532696A (ja) * 1990-09-28 1993-02-09 Takeda Chem Ind Ltd 副甲状腺ホルモン誘導体
WO1993006846A1 (en) * 1991-10-10 1993-04-15 Pang Peter K T Parathyroid hormone analogues and use in osteoporosis treatment
US5434246A (en) * 1992-03-19 1995-07-18 Takeda Chemical Industries, Ltd. Parathyroid hormone derivatives
CA2098639A1 (en) * 1992-06-19 1993-12-20 K. Anne Kronis Bone stimulating, non-vasoactive parathyroid hormone variants
US5821225A (en) * 1992-07-14 1998-10-13 Syntex (U.S.A.) Inc. Method for the treatment of corticosteroid induced osteopenia comprising administration of modified PTH or PTHrp
US5589452A (en) * 1992-07-14 1996-12-31 Syntex (U.S.A.) Inc. Analogs of parathyroid hormone and parathyroid hormone related peptide: synthesis and use for the treatment of osteoporosis
AU672790B2 (en) * 1992-07-15 1996-10-17 Novartis Ag Variants of parathyroid hormone and its fragments
PL174772B1 (pl) 1993-01-06 1998-09-30 Kinerton Ltd Kompozycja farmaceutyczna zawierająca jonowy konjugat cząsteczkowy
WO1995002610A1 (en) * 1993-07-13 1995-01-26 Syntex (U.S.A.) Inc. Analogs of parathyroid hormone and parathyroid hormone related peptide: synthesis and use for the treatment of osteoporosis
WO1996019246A1 (en) * 1994-12-19 1996-06-27 Beth Israel Hospital Association Continuous low-dose administration of parathyroid hormone or its agonist
CA2178894A1 (en) * 1995-06-15 1996-12-16 Tsunehiko Fukuda Parathyroid hormone derivatives and their use
US5723577A (en) * 1995-07-13 1998-03-03 Biomeasure Inc. Analogs of parathyroid hormone

Also Published As

Publication number Publication date
AR038552A2 (es) 2005-01-19
CN1137898C (zh) 2004-02-11
AR051906A2 (es) 2007-02-14
ES2258286T3 (es) 2006-08-16
DK1645566T3 (da) 2010-09-27
CZ301497B6 (cs) 2010-03-24
ES2347154T3 (es) 2010-10-26
DE69735603D1 (de) 2006-05-18
DK0948541T3 (da) 2006-07-17
CZ239899A3 (cs) 2000-01-12
EP1645566A2 (en) 2006-04-12
NO993341D0 (no) 1999-07-06
PL191898B1 (pl) 2006-07-31
NZ336610A (en) 2001-07-27
JP2001508439A (ja) 2001-06-26
NO993341L (no) 1999-09-06
CZ298937B6 (cs) 2008-03-19
EP2206725A1 (en) 2010-07-14
IL130794A0 (en) 2001-01-28
PT948541E (pt) 2006-07-31
KR20060030006A (ko) 2006-04-07
ATE321784T1 (de) 2006-04-15
EP1645566B1 (en) 2010-06-16
RU2198182C2 (ru) 2003-02-10
CA2276614A1 (en) 1998-07-16
DE69735603T2 (de) 2006-11-30
SI1645566T1 (sl) 2010-11-30
HK1026215A1 (en) 2000-12-08
ATE471342T1 (de) 2010-07-15
EP0948541A2 (en) 1999-10-13
CA2276614C (en) 2002-06-11
AU5519998A (en) 1998-08-03
KR100699422B1 (ko) 2007-03-28
BR9714200A (pt) 2000-03-28
PT1645566E (pt) 2010-08-31
WO1998030590A2 (en) 1998-07-16
AU741584B2 (en) 2001-12-06
AR011517A1 (es) 2000-08-30
EP0948541B1 (en) 2006-03-29
KR100497709B1 (ko) 2005-06-23
US5955574A (en) 1999-09-21
HUP9904596A1 (hu) 2000-06-28
DE69739912D1 (de) 2010-07-29
EP1645566A3 (en) 2006-10-11
KR20000069952A (ko) 2000-11-25
PL334438A1 (en) 2000-02-28
CN1254347A (zh) 2000-05-24
HUP9904596A3 (en) 2000-07-28
WO1998030590A9 (en) 1999-08-19
JP3963482B2 (ja) 2007-08-22
WO1998030590A3 (en) 1998-12-10

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