SI0948541T1 - PTHrP analogi - Google Patents
PTHrP analogiInfo
- Publication number
- SI0948541T1 SI0948541T1 SI9730730T SI9730730T SI0948541T1 SI 0948541 T1 SI0948541 T1 SI 0948541T1 SI 9730730 T SI9730730 T SI 9730730T SI 9730730 T SI9730730 T SI 9730730T SI 0948541 T1 SI0948541 T1 SI 0948541T1
- Authority
- SI
- Slovenia
- Prior art keywords
- pthrp
- analogs
- Prior art date
Links
- 108700020797 Parathyroid Hormone-Related Proteins 0.000 title 1
- 102000043299 Parathyroid hormone-related Human genes 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/635—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Endocrinology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Diabetes (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/779,768 US5969095A (en) | 1995-07-13 | 1997-01-07 | Analogs of parathyroid hormone |
US08/813,534 US5955574A (en) | 1995-07-13 | 1997-03-07 | Analogs of parathyroid hormone |
PCT/US1997/022498 WO1998030590A2 (en) | 1997-01-07 | 1997-12-08 | Analogs of parathyroid hormone |
EP97951595A EP0948541B1 (en) | 1997-01-07 | 1997-12-08 | Analogs of PTHrP |
Publications (1)
Publication Number | Publication Date |
---|---|
SI0948541T1 true SI0948541T1 (sl) | 2006-06-30 |
Family
ID=27119618
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI9730730T SI0948541T1 (sl) | 1997-01-07 | 1997-12-08 | PTHrP analogi |
SI9730795T SI1645566T1 (sl) | 1997-01-07 | 1997-12-08 | Analogi paratioridnega hormona |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI9730795T SI1645566T1 (sl) | 1997-01-07 | 1997-12-08 | Analogi paratioridnega hormona |
Country Status (24)
Country | Link |
---|---|
US (1) | US5955574A (sl) |
EP (3) | EP1645566B1 (sl) |
JP (1) | JP3963482B2 (sl) |
KR (2) | KR100699422B1 (sl) |
CN (1) | CN1137898C (sl) |
AR (3) | AR011517A1 (sl) |
AT (2) | ATE471342T1 (sl) |
AU (1) | AU741584B2 (sl) |
BR (1) | BR9714200A (sl) |
CA (1) | CA2276614C (sl) |
CZ (2) | CZ301497B6 (sl) |
DE (2) | DE69739912D1 (sl) |
DK (2) | DK0948541T3 (sl) |
ES (2) | ES2347154T3 (sl) |
HK (1) | HK1026215A1 (sl) |
HU (1) | HUP9904596A3 (sl) |
IL (1) | IL130794A0 (sl) |
NO (1) | NO993341L (sl) |
NZ (1) | NZ336610A (sl) |
PL (1) | PL191898B1 (sl) |
PT (2) | PT948541E (sl) |
RU (1) | RU2198182C2 (sl) |
SI (2) | SI0948541T1 (sl) |
WO (1) | WO1998030590A2 (sl) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6544949B1 (en) * | 1995-07-13 | 2003-04-08 | Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S. | Analogs of parathyroid hormone |
US7410948B2 (en) * | 1995-07-13 | 2008-08-12 | Societe De Conseils De Recherches Et D'applications Scientifiques, Sas | Analogs of parathyroid hormone |
EP1005359B1 (en) | 1997-09-09 | 2005-06-15 | F. Hoffmann-La Roche Ag | FRACTURE HEALING USING PTHrP ANALOGS |
AU3673699A (en) * | 1998-05-05 | 1999-11-23 | Beth Israel Deaconess Medical Center | Pth2 receptor selective compounds |
CA2335341A1 (en) * | 1998-07-20 | 2000-02-03 | Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R | Peptide analogues of pacap |
US6660843B1 (en) † | 1998-10-23 | 2003-12-09 | Amgen Inc. | Modified peptides as therapeutic agents |
EP1257576B1 (en) | 2000-02-18 | 2004-09-15 | Dabur Research Foundation | Vasoactive intestinal peptide analogs |
US20050124537A1 (en) * | 2000-04-27 | 2005-06-09 | Amgen Inc. | Modulators of receptors for parathyroid hormone and parathyroid hormone-related protein |
US6756480B2 (en) * | 2000-04-27 | 2004-06-29 | Amgen Inc. | Modulators of receptors for parathyroid hormone and parathyroid hormone-related protein |
CN101837120A (zh) | 2001-06-01 | 2010-09-22 | 诺瓦提斯公司 | 口服施用甲状旁腺激素和降钙素 |
US7572765B2 (en) | 2001-07-23 | 2009-08-11 | The General Hospital Corporation | Conformationally constrained parathyroid hormone (PTH) analogs |
KR20060056975A (ko) * | 2003-08-06 | 2006-05-25 | 로디아 인코포레이티드 | 뼈 성장 촉진방법 |
JP2009515535A (ja) | 2005-11-10 | 2009-04-16 | ボード オブ コントロール オブ ミシガン テクノロジカル ユニヴァーシティー | クロクマの副甲状腺ホルモン及びクロクマの副甲状腺ホルモンを使用する方法 |
AU2007322334B2 (en) * | 2006-10-03 | 2011-12-22 | Ipsen Pharma S.A.S. | Method of drug delivery for bone anabolic protein |
USRE49444E1 (en) | 2006-10-03 | 2023-03-07 | Radius Health, Inc. | Method of treating osteoporosis comprising administration of PTHrP analog |
US7803770B2 (en) * | 2006-10-03 | 2010-09-28 | Radius Health, Inc. | Method of treating osteoporosis comprising administration of PTHrP analog |
BRPI0719885B8 (pt) * | 2006-10-13 | 2021-05-25 | Lilly Co Eli | peptídeos peguilados como moduladores de receptores de pth, seus usos, e composição. |
AU2008282805B2 (en) | 2007-08-01 | 2014-05-01 | Chugai Pharmaceutical Co., Ltd. | Screening methods using G-protein coupled receptors and related compositions |
WO2010111617A2 (en) | 2009-03-27 | 2010-09-30 | Van Andel Research Institute | Parathyroid hormone peptides and parathyroid hormone-related protein peptides and methods of use |
JP2013512688A (ja) | 2009-12-07 | 2013-04-18 | ミシガン テクノロジカル ユニバーシティ | クロクマの副甲状腺ホルモン及びクロクマの副甲状腺ホルモンを使用する方法 |
MX342898B (es) | 2010-05-12 | 2016-10-18 | Radius Health Inc * | Regimen terapéutico de la sal de diclorhidrato del (r) -6-(2-(etil (4-2(etilamino) etil) bencil) amino)-4-metoxifenil)-5, 6,7,8-tetrahidronaftaleno-2-ol. |
CN103002906B (zh) | 2010-05-13 | 2017-12-29 | 总医院有限公司 | 甲状旁腺激素类似物及其应用 |
BR112013007685B1 (pt) | 2010-09-28 | 2021-11-09 | Radius Pharmaceuticals, Inc | Compostos moduladores de receptor andrógeno seletivos, composição farmacêutica compreendendo os referidos compostos, método de identificação de um composto capaz de modular um receptor andrógeno, usos de um composto ou da composição e processo para a preparação de um composto |
EP4039253A1 (en) | 2015-04-29 | 2022-08-10 | Radius Pharmaceuticals, Inc. | Methods of treating cancer |
CN108025042A (zh) * | 2015-07-06 | 2018-05-11 | 董正欣 | PTHrP类似物的新型制剂 |
AU2017281038B2 (en) | 2016-06-22 | 2021-09-09 | Ellipses Pharma Ltd | AR+ breast cancer treatment methods |
KR20230109795A (ko) | 2017-01-05 | 2023-07-20 | 래디어스 파마슈티컬스, 인코포레이티드 | Rad1901-2hcl의 다형 형태 |
US10996208B2 (en) | 2017-04-28 | 2021-05-04 | Radius Health, Inc. | Abaloparatide formulations and methods of testing, storing, modifying, and using same |
SG11202013177WA (en) | 2018-07-04 | 2021-01-28 | Radius Pharmaceuticals Inc | Polymorphic forms of rad 1901-2hcl |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3773919A (en) | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
IE52535B1 (en) | 1981-02-16 | 1987-12-09 | Ici Plc | Continuous release pharmaceutical compositions |
FR2550204B1 (fr) * | 1983-08-05 | 1987-11-13 | Toyo Jozo Kk | Derives peptidiques de (nle8,nle1b, tyr34)-h-pth |
EP0293158A3 (en) * | 1987-05-26 | 1990-05-09 | Merck & Co. Inc. | Parathyroid hormone antagonists |
JPH03504201A (ja) * | 1989-02-23 | 1991-09-19 | ゲゼルシャフト・フュア・ビオテクノロギッシェ・フォルシュンク・ミット・ベシュレンクテル・ハフツング (ゲー・ベー・エフ) | Pth変種をコードするdna配列、pth変種、発現ベクター、細菌宿主、利用と治療用組成物 |
CA2040264A1 (en) * | 1990-04-12 | 1991-10-13 | Tatsuhiko Kanmera | Parathyroid hormone antagonists |
JPH0532696A (ja) * | 1990-09-28 | 1993-02-09 | Takeda Chem Ind Ltd | 副甲状腺ホルモン誘導体 |
WO1993006846A1 (en) * | 1991-10-10 | 1993-04-15 | Pang Peter K T | Parathyroid hormone analogues and use in osteoporosis treatment |
US5434246A (en) * | 1992-03-19 | 1995-07-18 | Takeda Chemical Industries, Ltd. | Parathyroid hormone derivatives |
CA2098639A1 (en) * | 1992-06-19 | 1993-12-20 | K. Anne Kronis | Bone stimulating, non-vasoactive parathyroid hormone variants |
US5589452A (en) * | 1992-07-14 | 1996-12-31 | Syntex (U.S.A.) Inc. | Analogs of parathyroid hormone and parathyroid hormone related peptide: synthesis and use for the treatment of osteoporosis |
US5821225A (en) * | 1992-07-14 | 1998-10-13 | Syntex (U.S.A.) Inc. | Method for the treatment of corticosteroid induced osteopenia comprising administration of modified PTH or PTHrp |
AU672790B2 (en) * | 1992-07-15 | 1996-10-17 | Novartis Ag | Variants of parathyroid hormone and its fragments |
HU220137B (hu) | 1993-01-06 | 2001-11-28 | Kinerton Ltd. | Biológiailag lebontható poliészterek és biológiailag aktív polipeptidek ionos molekuláris konjugátumai, eljárás ezek előállítására és eljárás mikrorészecskék előállítására |
CN1070500C (zh) * | 1993-07-13 | 2001-09-05 | 森德克斯(美国)股份有限公司 | 甲状旁腺激素类似物和甲状旁腺激素相关肽:合成和治疗骨质疏松症的用途 |
JPH10511095A (ja) * | 1994-12-19 | 1998-10-27 | ベス イスラエル ディーコネス メディカル センター インコーポレイテッド | 副甲状腺ホルモン又はその作動薬の低用量継続投与 |
CA2178894A1 (en) * | 1995-06-15 | 1996-12-16 | Tsunehiko Fukuda | Parathyroid hormone derivatives and their use |
US5723577A (en) * | 1995-07-13 | 1998-03-03 | Biomeasure Inc. | Analogs of parathyroid hormone |
-
1997
- 1997-03-07 US US08/813,534 patent/US5955574A/en not_active Expired - Lifetime
- 1997-12-08 BR BR9714200-0A patent/BR9714200A/pt not_active IP Right Cessation
- 1997-12-08 EP EP05026436A patent/EP1645566B1/en not_active Expired - Lifetime
- 1997-12-08 AT AT05026436T patent/ATE471342T1/de active
- 1997-12-08 PT PT97951595T patent/PT948541E/pt unknown
- 1997-12-08 SI SI9730730T patent/SI0948541T1/sl unknown
- 1997-12-08 CZ CZ20050594A patent/CZ301497B6/cs not_active IP Right Cessation
- 1997-12-08 DK DK97951595T patent/DK0948541T3/da active
- 1997-12-08 WO PCT/US1997/022498 patent/WO1998030590A2/en active IP Right Grant
- 1997-12-08 EP EP10156965A patent/EP2206725A1/en not_active Withdrawn
- 1997-12-08 RU RU99117145/04A patent/RU2198182C2/ru not_active IP Right Cessation
- 1997-12-08 IL IL13079497A patent/IL130794A0/xx not_active IP Right Cessation
- 1997-12-08 AU AU55199/98A patent/AU741584B2/en not_active Ceased
- 1997-12-08 DE DE69739912T patent/DE69739912D1/de not_active Expired - Lifetime
- 1997-12-08 AT AT97951595T patent/ATE321784T1/de active
- 1997-12-08 CA CA002276614A patent/CA2276614C/en not_active Expired - Fee Related
- 1997-12-08 DK DK05026436.5T patent/DK1645566T3/da active
- 1997-12-08 ES ES05026436T patent/ES2347154T3/es not_active Expired - Lifetime
- 1997-12-08 CN CNB971819157A patent/CN1137898C/zh not_active Expired - Fee Related
- 1997-12-08 PL PL334438A patent/PL191898B1/pl not_active IP Right Cessation
- 1997-12-08 ES ES97951595T patent/ES2258286T3/es not_active Expired - Lifetime
- 1997-12-08 PT PT05026436T patent/PT1645566E/pt unknown
- 1997-12-08 EP EP97951595A patent/EP0948541B1/en not_active Expired - Lifetime
- 1997-12-08 DE DE69735603T patent/DE69735603T2/de not_active Expired - Lifetime
- 1997-12-08 HU HU9904596A patent/HUP9904596A3/hu unknown
- 1997-12-08 NZ NZ336610A patent/NZ336610A/en not_active IP Right Cessation
- 1997-12-08 SI SI9730795T patent/SI1645566T1/sl unknown
- 1997-12-08 KR KR1020057003295A patent/KR100699422B1/ko not_active IP Right Cessation
- 1997-12-08 KR KR10-1999-7006165A patent/KR100497709B1/ko not_active IP Right Cessation
- 1997-12-08 CZ CZ0239899A patent/CZ298937B6/cs not_active IP Right Cessation
- 1997-12-08 JP JP53086598A patent/JP3963482B2/ja not_active Expired - Fee Related
-
1998
- 1998-01-06 AR ARP980100058A patent/AR011517A1/es active IP Right Grant
-
1999
- 1999-07-06 NO NO993341A patent/NO993341L/no not_active Application Discontinuation
-
2000
- 2000-09-01 HK HK00105467A patent/HK1026215A1/xx not_active IP Right Cessation
-
2003
- 2003-02-17 AR ARP030100515A patent/AR038552A2/es active IP Right Grant
-
2006
- 2006-01-18 AR ARP060100191A patent/AR051906A2/es unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
SI0948541T1 (sl) | PTHrP analogi | |
PL339551A1 (en) | Derivatives of rezorcin | |
IL134719A0 (en) | FRACTURE HEALING USING PTHrP ANALOGS | |
PL334846A1 (en) | Sulphamidic inhibitors of metaloproteases | |
EP1033994A4 (en) | METHOD FOR PRODUCING BIOGINKGO | |
EP0996458A4 (en) | SANDRAMYCIN ANALOG | |
SG67408A1 (en) | Synthesis of analogs of pth and pthrp | |
PL334769A1 (en) | Derivatives of 5-aroylnaphtene | |
PL337612A1 (en) | Crystalline form of roxyfiban | |
ZA985064B (en) | Derivatives of pentaerythrits | |
IL124387A0 (en) | Preparation of 5-Methyleneoxazolines | |
ZA986465B (en) | Preparation of fluorinated compounds | |
GB2329384B (en) | Preparation of 1-chloro-1-cyclopropylethene | |
TW319017U (en) | Improved structure of mousetraps | |
TW312301U (en) | Improved structure of earmask | |
PL327430A1 (en) | Set of shaped components | |
GB9722026D0 (en) | Use of compounds | |
TW357554U (en) | Improvement of shinguards | |
HU9700442D0 (en) | Compounds of pharmaceutical activity | |
TW323471U (en) | Improved structure of hairclip | |
TW312131U (en) | Improved structure of earflaps | |
TW317745U (en) | Improved structure of mini-duster | |
IL125503A0 (en) | Crystalline forms of progestagens | |
TW313845U (en) | Improved structure of pacifier | |
TW314733U (en) | Structure of hairclip |