NO20003139D0 - FremgangsmÕte for syntese av 1,3-dioler - Google Patents

FremgangsmÕte for syntese av 1,3-dioler

Info

Publication number
NO20003139D0
NO20003139D0 NO20003139A NO20003139A NO20003139D0 NO 20003139 D0 NO20003139 D0 NO 20003139D0 NO 20003139 A NO20003139 A NO 20003139A NO 20003139 A NO20003139 A NO 20003139A NO 20003139 D0 NO20003139 D0 NO 20003139D0
Authority
NO
Norway
Prior art keywords
diols
synthesis
Prior art date
Application number
NO20003139A
Other languages
English (en)
Norwegian (no)
Other versions
NO20003139L (no
Inventor
Richard Joseph Mccabe
Thomas Norman Nanninga
Robert Lee Bosch
Robert Joseph Stahl
Original Assignee
Warner Lambert Export Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Export Ltd filed Critical Warner Lambert Export Ltd
Publication of NO20003139L publication Critical patent/NO20003139L/no
Publication of NO20003139D0 publication Critical patent/NO20003139D0/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36Oxygen or sulfur atoms
    • C07D207/402,5-Pyrrolidine-diones
    • C07D207/4162,5-Pyrrolidine-diones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B41/00Formation or introduction of functional groups containing oxygen
    • C07B41/02Formation or introduction of functional groups containing oxygen of hydroxy or O-metal groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00Preparation of carboxylic acid nitriles
    • C07C253/30Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • C07C255/01Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/19Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and carboxyl groups, other than cyano groups, bound to the same saturated acyclic carbon skeleton
    • C07C255/20Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and carboxyl groups, other than cyano groups, bound to the same saturated acyclic carbon skeleton the carbon skeleton being further substituted by singly-bound oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • C07C255/01Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/19Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and carboxyl groups, other than cyano groups, bound to the same saturated acyclic carbon skeleton
    • C07C255/21Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and carboxyl groups, other than cyano groups, bound to the same saturated acyclic carbon skeleton the carbon skeleton being further substituted by doubly-bound oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07Optical isomers
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Pyrrole Compounds (AREA)
NO20003139A 1997-12-19 2000-06-16 FremgangsmÕte for syntese av 1,3-dioler NO20003139D0 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6819397P 1997-12-19 1997-12-19
PCT/US1998/025493 WO1999032434A1 (en) 1997-12-19 1998-12-02 Process for the synthesis of 1,3-diols

Publications (2)

Publication Number Publication Date
NO20003139L NO20003139L (no) 2000-06-16
NO20003139D0 true NO20003139D0 (no) 2000-06-16

Family

ID=22081016

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20003139A NO20003139D0 (no) 1997-12-19 2000-06-16 FremgangsmÕte for syntese av 1,3-dioler

Country Status (31)

Country Link
US (4) US6433213B1 (es)
EP (1) EP1054860B1 (es)
JP (1) JP2001526256A (es)
KR (2) KR100681366B1 (es)
AR (1) AR014943A1 (es)
AT (1) ATE360608T1 (es)
AU (1) AU755543B2 (es)
BR (1) BR9813760A (es)
CA (1) CA2305618C (es)
CO (1) CO4990941A1 (es)
CU (1) CU22939A3 (es)
CY (1) CY1106612T1 (es)
DE (1) DE69837681T2 (es)
DK (1) DK1054860T3 (es)
ES (1) ES2284219T3 (es)
GT (2) GT199800197AA (es)
HN (1) HN1998000187A (es)
HU (1) HUP0100252A3 (es)
IL (1) IL135562A (es)
IS (1) IS5447A (es)
MY (1) MY118726A (es)
NO (1) NO20003139D0 (es)
NZ (1) NZ504346A (es)
PA (1) PA8464901A1 (es)
PE (1) PE20000136A1 (es)
PL (1) PL193678B1 (es)
PT (1) PT1054860E (es)
SV (1) SV1998000153A (es)
TW (1) TW444000B (es)
WO (1) WO1999032434A1 (es)
ZA (1) ZA9811586B (es)

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WO2001044181A1 (en) 1999-12-17 2001-06-21 Warner Lambert Research And Development Ireland Limited A process for producing crystalline atorvastatin calcium
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AU2004272365A1 (en) * 2003-09-17 2005-03-24 Warner-Lambert Company Llc Crystalline forms of `R-(R*,R*))-2-(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-`(phenylamino)carbonyl!-1H-pyrrole-1-heptanoic acid
AU2003272080A1 (en) * 2003-09-18 2005-04-06 Biocon Limited Novel process for the preparation of tert-butyl 6-cyano-5-hydroxy-3-oxohexanoate
CA2550742A1 (en) * 2003-12-24 2005-07-14 Teva Pharmaceutical Industries Ltd. Process for preparation of statins with high syn to anti ratio
US7851624B2 (en) * 2003-12-24 2010-12-14 Teva Pharamaceutical Industries Ltd. Triol form of rosuvastatin and synthesis of rosuvastatin
RU2330840C1 (ru) * 2004-04-16 2008-08-10 Пфайзер Продактс Инк. Способ получения аморфного кальций аторвастатина
ES2739493T3 (es) 2004-05-05 2020-01-31 Pfizer Prod Inc Formas de sal de de atorvastatina con benetamina
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CA2589537A1 (en) * 2004-12-02 2006-06-08 Stephen Craig Dyar Pharmaceutical compositions of amorphous atorvastatin and process for preparing same
US20090221852A1 (en) * 2005-09-09 2009-09-03 Pfizer Inc. Preparation of an Atorvastatin Intermediate
DE602005014686D1 (de) * 2005-09-09 2009-07-09 Pfizer Science & Tech Ltd Herstellung eines atorvastatin-zwischenprodukts
CA2547216A1 (en) 2005-09-21 2007-03-21 Renuka D. Reddy Process for annealing amorphous atorvastatin
DE602006014193D1 (de) 2005-11-21 2010-06-17 Warner Lambert Co Neue formen von är-(r*,r*)ü-2-(4-fluorphenyl)-b,d-dihydroxy-5-(1-methylethyl)-3-phenyl-4-ä(phenylamino)carbonylü-1h-pyrrol-1-heptansäure-magnesium
CN101528917B (zh) 2006-10-02 2015-07-29 科德克希思公司 用于制备立体异构纯的他汀类及其合成中间体的组合物和方法
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EP2379713A4 (en) * 2008-12-18 2013-07-10 Codexis Inc RECOMBINANT HALOHYDRIN DEHALOGENASE POLYPEPTIDES
SI2373609T1 (sl) 2008-12-19 2013-12-31 Krka, D.D., Novo Mesto Uporaba amfifilnih spojin za kontrolirano kristalizacijo statinov in intermediatov statinov
EP2327682A1 (en) 2009-10-29 2011-06-01 KRKA, D.D., Novo Mesto Use of amphiphilic compounds for controlled crystallization of statins and statin intermediates
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CN111978286A (zh) * 2020-08-21 2020-11-24 江苏万年长药业有限公司 一种制备ats-8的方法

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Also Published As

Publication number Publication date
KR100668575B1 (ko) 2007-01-17
MY118726A (en) 2005-01-31
PT1054860E (pt) 2007-06-22
AU1707499A (en) 1999-07-12
DK1054860T3 (da) 2007-07-02
AU755543B2 (en) 2002-12-12
IL135562A (en) 2005-08-31
HUP0100252A3 (en) 2002-12-28
CY1106612T1 (el) 2012-01-25
US20050197500A1 (en) 2005-09-08
US6962994B2 (en) 2005-11-08
HN1998000187A (es) 1999-10-22
BR9813760A (pt) 2000-10-03
NO20003139L (no) 2000-06-16
CA2305618C (en) 2004-08-17
PL341294A1 (en) 2001-04-09
CA2305618A1 (en) 1999-07-01
ZA9811586B (en) 1999-06-17
CO4990941A1 (es) 2000-12-26
KR20010033315A (ko) 2001-04-25
EP1054860A1 (en) 2000-11-29
SV1998000153A (es) 1999-09-30
GT199800197AA (es) 2000-06-06
PE20000136A1 (es) 2000-03-11
DE69837681D1 (de) 2007-06-06
PL193678B1 (pl) 2007-03-30
WO1999032434A1 (en) 1999-07-01
NZ504346A (en) 2001-11-30
TW444000B (en) 2001-07-01
ES2284219T3 (es) 2007-11-01
IS5447A (is) 2000-04-14
DE69837681T2 (de) 2008-01-10
JP2001526256A (ja) 2001-12-18
ATE360608T1 (de) 2007-05-15
US7232915B2 (en) 2007-06-19
GT199800197A (es) 2000-06-06
US6596879B2 (en) 2003-07-22
AR014943A1 (es) 2001-04-11
HUP0100252A1 (hu) 2001-07-30
CU22939A3 (es) 2004-04-13
EP1054860B1 (en) 2007-04-25
US20020161021A1 (en) 2002-10-31
IL135562A0 (en) 2001-05-20
US6433213B1 (en) 2002-08-13
PA8464901A1 (es) 2000-05-24
KR100681366B1 (ko) 2007-02-12
US20040006231A1 (en) 2004-01-08
KR20060080941A (ko) 2006-07-11

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