NO20002789D0 - Hydrofobisk-modifiserte proteinpreparater og fremgangsmÕter for fremstilling derav - Google Patents

Hydrofobisk-modifiserte proteinpreparater og fremgangsmÕter for fremstilling derav

Info

Publication number
NO20002789D0
NO20002789D0 NO20002789A NO20002789A NO20002789D0 NO 20002789 D0 NO20002789 D0 NO 20002789D0 NO 20002789 A NO20002789 A NO 20002789A NO 20002789 A NO20002789 A NO 20002789A NO 20002789 D0 NO20002789 D0 NO 20002789D0
Authority
NO
Norway
Prior art keywords
protein
processes
preparation
hydrophobically modified
modified protein
Prior art date
Application number
NO20002789A
Other languages
English (en)
Other versions
NO20002789L (no
Inventor
R Blake Pepinsky
Darren P Baker
Dingyi Wen
Kevin P Williams
Ellen A Garber
Frederick R Taylor
Alphonse Galdes
Jeffrey Porter
Original Assignee
Biogen Inc
Ontogeny Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogen Inc, Ontogeny Inc filed Critical Biogen Inc
Publication of NO20002789D0 publication Critical patent/NO20002789D0/no
Publication of NO20002789L publication Critical patent/NO20002789L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
    • C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Analytical Chemistry (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Graft Or Block Polymers (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
NO20002789A 1997-12-03 2000-05-31 Hydrofobisk-modifiserte proteinpreparater og fremgangsmater for fremstilling derav NO20002789L (no)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US6742397P 1997-12-03 1997-12-03
US7893598P 1998-03-20 1998-03-20
US8968598P 1998-06-17 1998-06-17
US9980098P 1998-09-10 1998-09-10
PCT/US1998/025676 WO1999028343A2 (en) 1997-12-03 1998-12-03 Hydrophobically-modified protein compositions and methods

Publications (2)

Publication Number Publication Date
NO20002789D0 true NO20002789D0 (no) 2000-05-31
NO20002789L NO20002789L (no) 2000-08-02

Family

ID=27490628

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20002789A NO20002789L (no) 1997-12-03 2000-05-31 Hydrofobisk-modifiserte proteinpreparater og fremgangsmater for fremstilling derav

Country Status (26)

Country Link
US (1) US6444793B1 (no)
EP (1) EP1036092B1 (no)
JP (1) JP4289788B2 (no)
KR (1) KR20010032753A (no)
CN (1) CN1294595A (no)
AT (1) ATE295372T1 (no)
AU (1) AU757497B2 (no)
BR (1) BR9815142A (no)
CA (1) CA2309806A1 (no)
CZ (1) CZ20002008A3 (no)
DE (1) DE69830192T2 (no)
DK (1) DK1036092T3 (no)
EA (1) EA003739B1 (no)
EE (1) EE200000308A (no)
ES (1) ES2243018T3 (no)
HK (1) HK1030953A1 (no)
HU (1) HUP0100535A3 (no)
IL (2) IL136137A0 (no)
IS (1) IS2163B (no)
MX (1) MXPA00005494A (no)
NO (1) NO20002789L (no)
NZ (1) NZ504752A (no)
PL (1) PL197833B1 (no)
PT (1) PT1036092E (no)
TR (1) TR200001612T2 (no)
WO (1) WO1999028343A2 (no)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1034269A1 (en) * 1997-11-28 2000-09-13 Roche Diagnostics GmbH An active hedgehog-protein-mutant, a process for its preparation and its use for pharmaceutical purposes
IL136137A0 (en) 1997-12-03 2001-05-20 Biogen Inc Hydrophobically-modified protein compositions and methods
US6897297B1 (en) 1997-12-03 2005-05-24 Curis, Inc. Hydrophobically-modified protein compositions and methods
EP0953576B1 (en) * 1998-04-30 2005-11-02 Curis, Inc. Active hedgehog protein conjugate, process for its production and use
TW570805B (en) 1998-09-01 2004-01-11 Hoffmann La Roche Water-soluble pharmaceutical composition in an ionic complex
JP4574012B2 (ja) * 1998-11-02 2010-11-04 キュリス，インコーポレイテッド ヘッジホッグ活性の機能的アンタゴニスト
JP2003524388A (ja) * 1998-12-03 2003-08-19 バイオジェン インコーポレイテッド 興奮毒性を含む疾患を治療するための方法及び組成物
EP1025861A1 (de) * 1999-02-04 2000-08-09 Roche Diagnostics GmbH Pharmazeutische Zusammensetzung von hydrophob modifizierten Hedgehog-Proteinen und deren Verwendung
AU782493B2 (en) * 1999-06-01 2005-08-04 Curis, Inc. Polymer conjugates of hedgehog proteins and uses
IL149202A0 (en) * 1999-11-05 2002-11-10 Biogen Inc Hedgehog fusion proteins and uses
AU2005203058C1 (en) * 1999-11-05 2009-07-02 Curis, Inc. Hedgehog fusion proteins and uses
WO2001082994A1 (en) * 2000-04-28 2001-11-08 Curis, Inc. Methods and reagents for tissue engineering of cartilage in vitro
WO2003089454A2 (en) * 2002-04-19 2003-10-30 California Institute Of Technology Unnatural amino acid containing display libraries
EP1773375A1 (en) 2004-07-14 2007-04-18 University of Utah Research Foundation Netrin-related compositions and uses
EP1862180A4 (en) * 2005-03-25 2010-09-15 Takeda Pharmaceutical PROPHYLACTIC AND THERAPEUTIC AGENT AGAINST CANCER
RU2420580C2 (ru) * 2005-11-11 2011-06-10 Протеоджен Био С.Р.Л. Способ преобразования водорастворимых активных белков в гидрофобные активные белки, их применение для получения мономолекулярных слоев ориентированных активных белков и устройства, включающие водорастворимые активные белки, преобразованные в гидрофобные активные белки
US8273747B2 (en) 2006-11-02 2012-09-25 Curis, Inc. Small organic molecule regulators of cell proliferation
KR100876657B1 (ko) * 2007-10-15 2009-01-07 한국기계연구원 표면개질된 마이크로비드와 마이크로비드 어레이칩의제조방법과 마이크로비드 어레이칩을 이용한 질병특이항원의 확인방법
CA2716255C (en) * 2008-02-21 2016-11-29 Dermacare Neuroscience Institute Cosmetic and dermatological formulations of mntf peptides
US20100316566A1 (en) * 2008-02-27 2010-12-16 Radiomedix Inc. Radiolabeled hedgehog derivatives for imaging and therapy
UA107571C2 (xx) * 2009-04-03 2015-01-26 Фармацевтична композиція
CN103665095A (zh) * 2012-09-11 2014-03-26 中国人民解放军军事医学科学院卫生学环境医学研究所 一种疏水性多肽修饰抗体的合成方法
CN106928454B (zh) * 2015-12-30 2021-07-20 北京大学 聚氨基酸化合物
CN108147990B (zh) * 2016-12-02 2023-01-24 上海中医药大学 一种膜锚定元件及其应用
IL302108A (en) 2017-10-25 2023-06-01 Ac Immune Sa Preparations of phosphorylated tau peptides and uses thereof

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5374548A (en) * 1986-05-02 1994-12-20 Genentech, Inc. Methods and compositions for the attachment of proteins to liposomes using a glycophospholipid anchor
US5399347A (en) 1987-06-24 1995-03-21 Autoimmune, Inc. Method of treating rheumatoid arthritis with type II collagen
US5409611A (en) * 1988-03-24 1995-04-25 Terrapin Technoogies, Inc. Method to identify analyte-binding ligands
US5130297A (en) 1988-06-23 1992-07-14 Anergen, Inc. Conjugates useful in ameliorating autoimmunity MHC-II-peptide
US5824315A (en) * 1993-10-25 1998-10-20 Anergen, Inc. Binding affinity of antigenic peptides for MHC molecules
US6281332B1 (en) * 1994-12-02 2001-08-28 The Johns Hopkins University School Of Medicine Hedgehog-derived polypeptides
US5869602A (en) * 1995-03-17 1999-02-09 Novo Nordisk A/S Peptide derivatives
AU728541B2 (en) * 1996-10-07 2001-01-11 Johns Hopkins University School Of Medicine, The Novel hedgehog-derived polypeptides
IL136137A0 (en) 1997-12-03 2001-05-20 Biogen Inc Hydrophobically-modified protein compositions and methods

Also Published As

Publication number Publication date
NZ504752A (en) 2002-10-25
IS5499A (is) 2000-05-15
EP1036092B1 (en) 2005-05-11
CA2309806A1 (en) 1999-06-10
EE200000308A (et) 2001-10-15
PL197833B1 (pl) 2008-04-30
WO1999028343A2 (en) 1999-06-10
JP2001525336A (ja) 2001-12-11
AU1996699A (en) 1999-06-16
DK1036092T3 (da) 2005-08-15
WO1999028343A3 (en) 1999-08-12
NO20002789L (no) 2000-08-02
ATE295372T1 (de) 2005-05-15
WO1999028343A9 (en) 1999-10-14
KR20010032753A (ko) 2001-04-25
DE69830192D1 (de) 2005-06-16
DE69830192T2 (de) 2006-01-12
HK1030953A1 (en) 2001-05-25
IS2163B (is) 2006-11-15
AU757497B2 (en) 2003-02-20
EA003739B1 (ru) 2003-08-28
JP4289788B2 (ja) 2009-07-01
PT1036092E (pt) 2005-09-30
EP1036092A2 (en) 2000-09-20
EA200000605A1 (ru) 2000-12-25
CZ20002008A3 (cs) 2001-11-14
IL136137A (en) 2009-09-22
MXPA00005494A (es) 2003-05-19
CN1294595A (zh) 2001-05-09
IL136137A0 (en) 2001-05-20
HUP0100535A2 (hu) 2001-06-28
US6444793B1 (en) 2002-09-03
TR200001612T2 (tr) 2001-01-22
ES2243018T3 (es) 2005-11-16
PL341430A1 (en) 2001-04-09
HUP0100535A3 (en) 2003-09-29
BR9815142A (pt) 2000-10-10

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