NO178432C - Tetrazolmellomprodukt - Google Patents

Tetrazolmellomprodukt

Info

Publication number
NO178432C
NO178432C NO880802A NO880802A NO178432C NO 178432 C NO178432 C NO 178432C NO 880802 A NO880802 A NO 880802A NO 880802 A NO880802 A NO 880802A NO 178432 C NO178432 C NO 178432C
Authority
NO
Norway
Prior art keywords
tetrazole
Prior art date
Application number
NO880802A
Other languages
English (en)
Norwegian (no)
Other versions
NO178432B (no
NO880802D0 (no
NO880802L (no
Inventor
John Jessen Wright
Sing-Yuen Sit
Neelakantan Balasubramanian
Peter J Brown
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of NO880802D0 publication Critical patent/NO880802D0/no
Publication of NO880802L publication Critical patent/NO880802L/no
Priority to NO924942A priority Critical patent/NO178190C/no
Priority to NO924941A priority patent/NO179207C/no
Priority to NO942083A priority patent/NO178767C/no
Publication of NO178432B publication Critical patent/NO178432B/no
Publication of NO178432C publication Critical patent/NO178432C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6524Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having four or more nitrogen atoms as the only ring hetero atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D257/00Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04Five-membered rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
NO880802A 1987-02-25 1988-02-24 Tetrazolmellomprodukt NO178432C (no)

Priority Applications (3)

Application Number Priority Date Filing Date Title
NO924942A NO178190C (no) 1987-02-25 1992-12-21 3,3-bis-(eventuelt substituert)-fenyl-2-(1-metyl-1H-tetrazol-5-yl)-1-propenal
NO924941A NO179207C (no) 1987-02-25 1992-12-21 Analogifremgangsmåte til fremstilling av en terapeutisk aktiv forbindelse
NO942083A NO178767C (no) 1987-02-25 1994-06-06 Tetrazolmellomprodukt og fremgangsmåte til fremstilling derav

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1855887A 1987-02-25 1987-02-25
US07/151,512 US4898949A (en) 1987-02-25 1988-02-18 Intermediates for the preparation of antihypercholesterolemic tetrazole compounds

Publications (4)

Publication Number Publication Date
NO880802D0 NO880802D0 (no) 1988-02-24
NO880802L NO880802L (no) 1988-08-26
NO178432B NO178432B (no) 1995-12-18
NO178432C true NO178432C (no) 1996-03-27

Family

ID=26691250

Family Applications (1)

Application Number Title Priority Date Filing Date
NO880802A NO178432C (no) 1987-02-25 1988-02-24 Tetrazolmellomprodukt

Country Status (27)

Country Link
US (1) US4898949A (fr)
JP (1) JP2603284B2 (fr)
KR (1) KR960007167B1 (fr)
CN (1) CN1030077C (fr)
AT (1) AT395588B (fr)
AU (1) AU610562B2 (fr)
BE (1) BE1002115A3 (fr)
CA (1) CA1328269C (fr)
CH (1) CH678182A5 (fr)
DE (1) DE3805789C2 (fr)
DK (2) DK97388A (fr)
ES (1) ES2009547A6 (fr)
FI (1) FI96600C (fr)
FR (1) FR2611201B1 (fr)
GB (1) GB2202845B (fr)
GR (1) GR1000473B (fr)
HU (3) HU201534B (fr)
IE (1) IE61608B1 (fr)
IT (1) IT1216752B (fr)
LU (1) LU87143A1 (fr)
MY (1) MY102290A (fr)
NL (1) NL8800468A (fr)
NO (1) NO178432C (fr)
NZ (1) NZ223621A (fr)
PT (1) PT86821B (fr)
SE (3) SE504553C2 (fr)
YU (1) YU46781B (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4870187A (en) * 1988-08-23 1989-09-26 Bristol-Myers Company Antihypercholesterolemic tetrazol-1-yl compounds
FI94339C (fi) 1989-07-21 1995-08-25 Warner Lambert Co Menetelmä farmaseuttisesti käyttökelpoisen /R-(R*,R*)/-2-(4-fluorifenyyli)- , -dihydroksi-5-(1-metyylietyyli)-3-fenyyli-4-/(fenyyliamino)karbonyyli/-1H-pyrroli-1-heptaanihapon ja sen farmaseuttisesti hyväksyttävien suolojen valmistamiseksi
US5260325A (en) * 1991-08-19 1993-11-09 E. I. Du Pont De Nemours And Company Angiotensin II receptor blocking tertiary amides
CA2137049A1 (fr) * 1993-12-15 1995-06-16 John K. Thottathil Sels d'acides amines de composes antihypercholesterolemiques a base de tetrazole et leur methode de preparation
KR100681366B1 (ko) * 1997-12-19 2007-02-12 워너-램버트 익스포트 리미티드 1,3-디올의 합성방법

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4160100A (en) * 1973-03-23 1979-07-03 American Home Products Corporation Oxamic acid derivatives
US4013647A (en) * 1976-03-23 1977-03-22 American Home Products Corporation Morpholine containing tetrazole-5-carboxamide derivatives
JPS53147073A (en) * 1977-05-24 1978-12-21 Sankyo Co Ltd Mevalonolactone derivatives
NZ194557A (en) * 1979-08-17 1984-09-28 Merck & Co Inc Substituted pyranone derivatives;dihydroxy acids therefrom;pharmaceutical compositions
US4567289A (en) * 1979-08-17 1986-01-28 Merck & Co., Inc. Substituted pyranone inhibitors of cholesterol synthesis
US4375475A (en) * 1979-08-17 1983-03-01 Merck & Co., Inc. Substituted pyranone inhibitors of cholesterol synthesis
EP0068038B1 (fr) * 1981-06-29 1985-09-25 Merck & Co. Inc. (+)-(4R.6S)-(E)-6-(2-(4'-fluoro-3,3',5-triméthyl-(1,1'-biphényl)-2-yle)éthenyl)-3,4,5,6-tétrahydro-4-hydroxy-2H-pyran-2-one, un procédé pour sa fabrication et une composition pharmaceutique la contenant
AU570021B2 (en) * 1982-11-22 1988-03-03 Novartis Ag Analogs of mevalolactone
US4739073A (en) * 1983-11-04 1988-04-19 Sandoz Pharmaceuticals Corp. Intermediates in the synthesis of indole analogs of mevalonolactone and derivatives thereof
PT77996B (en) * 1983-01-24 1986-05-30 Sandoz Sa Process of the preparations of mevalonelactone analogs and derivatives thereof and of pharmaceutical compositions containing them
US5105017A (en) * 1983-07-18 1992-04-14 Eli Lilly And Company Leukotriene antagonist intermediates
CA1327360C (fr) * 1983-11-14 1994-03-01 William F. Hoffman Analogues oxo d'agents antihypercholesterolemiants ayant les caracteristiques de la mevinoline
US4613610A (en) * 1984-06-22 1986-09-23 Sandoz Pharmaceuticals Corp. Cholesterol biosynthesis inhibiting pyrazole analogs of mevalonolactone and its derivatives
JPS61502467A (ja) * 1984-06-22 1986-10-30 サンド・アクチエンゲゼルシヤフト メバロノラクトンのピラゾ−ル同族体およびその誘導体、それらの製造方法ならびに用途
US4668794A (en) * 1985-05-22 1987-05-26 Sandoz Pharm. Corp. Intermediate imidazole acrolein analogs
US4621099A (en) * 1985-09-23 1986-11-04 Usv Pharmaceutical Corporation Polyene compounds useful in the treatment of allergic responses
US4681893A (en) * 1986-05-30 1987-07-21 Warner-Lambert Company Trans-6-[2-(3- or 4-carboxamido-substituted pyrrol-1-yl)alkyl]-4-hydroxypyran-2-one inhibitors of cholesterol synthesis
US4678806A (en) * 1986-09-02 1987-07-07 Merck & Co., Inc. Prodrugs of antihypercholesterolemic compounds
AU601264B2 (en) * 1987-02-25 1990-09-06 Bristol-Myers Squibb Company Antihypercholesterolemic tetrazole compounds

Also Published As

Publication number Publication date
AU1213288A (en) 1988-09-01
FI96600B (fi) 1996-04-15
DK97388D0 (da) 1988-02-24
ES2009547A6 (es) 1989-10-01
SE503201C2 (sv) 1996-04-15
IT8819526A0 (it) 1988-02-24
LU87143A1 (fr) 1988-09-20
JPS63290872A (ja) 1988-11-28
FR2611201A1 (fr) 1988-08-26
GB8804281D0 (en) 1988-03-23
FI880868A0 (fi) 1988-02-24
NZ223621A (en) 1991-06-25
ATA46088A (de) 1992-06-15
AT395588B (de) 1993-01-25
DE3805789C2 (de) 2001-05-31
CN1030077C (zh) 1995-10-18
MY102290A (en) 1992-05-15
GR880100100A (en) 1988-12-16
GB2202845B (en) 1991-05-22
SE9300977L (fr)
PT86821B (pt) 1992-05-29
IT1216752B (it) 1990-03-08
YU36488A (en) 1990-02-28
PT86821A (pt) 1988-03-01
HU201532B (en) 1990-11-28
GB2202845A (en) 1988-10-05
JP2603284B2 (ja) 1997-04-23
NO178432B (no) 1995-12-18
SE512485C2 (sv) 2000-03-20
CA1328269C (fr) 1994-04-05
NO880802D0 (no) 1988-02-24
GR1000473B (el) 1992-07-30
FI880868A (fi) 1988-08-26
IE880502L (en) 1988-08-18
HU201533B (en) 1990-11-28
KR960007167B1 (ko) 1996-05-29
YU46781B (sh) 1994-05-10
IE61608B1 (en) 1994-11-16
KR880009946A (ko) 1988-10-06
DK97388A (da) 1988-08-26
FR2611201B1 (fr) 1991-01-11
FI96600C (fi) 1996-07-25
HUT47258A (en) 1989-02-28
AU610562B2 (en) 1991-05-23
SE8800637L (sv) 1988-08-26
NO880802L (no) 1988-08-26
SE9300976D0 (sv) 1993-03-24
CH678182A5 (fr) 1991-08-15
BE1002115A3 (fr) 1990-07-10
DE3805789A1 (de) 1988-09-15
SE9300977D0 (sv) 1993-03-24
SE9300976L (fr) 1993-03-24
SE504553C2 (sv) 1997-03-03
US4898949A (en) 1990-02-06
SE8800637D0 (sv) 1988-02-24
NL8800468A (nl) 1988-09-16
HU201534B (en) 1990-11-28
CN1070642A (zh) 1993-04-07
HU895124D0 (fr) 1990-01-28
DK113897A (da) 1997-10-06

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