FI880868A0 - Välituotteina käyttökelpoisia tetratsoliyhdisteitä - Google Patents
Välituotteina käyttökelpoisia tetratsoliyhdisteitäInfo
- Publication number
- FI880868A0 FI880868A0 FI880868A FI880868A FI880868A0 FI 880868 A0 FI880868 A0 FI 880868A0 FI 880868 A FI880868 A FI 880868A FI 880868 A FI880868 A FI 880868A FI 880868 A0 FI880868 A0 FI 880868A0
- Authority
- FI
- Finland
- Prior art keywords
- intermediates
- compounds useful
- tetrazole compounds
- tetrazole
- useful
- Prior art date
Links
- -1 Tetrazole compounds Chemical class 0.000 title 1
- 239000000543 intermediate Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6524—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having four or more nitrogen atoms as the only ring hetero atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D257/04—Five-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hematology (AREA)
- Pharmacology & Pharmacy (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FI931579A FI96953C (fi) | 1987-02-25 | 1993-04-07 | Tetratsolijohdannaisia ja menetelmä niiden valmistamiseksi |
FI931580A FI96602C (fi) | 1987-02-25 | 1993-04-07 | Menetelmä terapeuttisesti aktiivisten tetratsolijohdannaisten valmistamiseksi |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US1855887A | 1987-02-25 | 1987-02-25 | |
US1855887 | 1987-02-25 | ||
US07/151,512 US4898949A (en) | 1987-02-25 | 1988-02-18 | Intermediates for the preparation of antihypercholesterolemic tetrazole compounds |
US15151288 | 1988-02-18 |
Publications (4)
Publication Number | Publication Date |
---|---|
FI880868A0 true FI880868A0 (fi) | 1988-02-24 |
FI880868A FI880868A (fi) | 1988-08-26 |
FI96600B FI96600B (fi) | 1996-04-15 |
FI96600C FI96600C (fi) | 1996-07-25 |
Family
ID=26691250
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI880868A FI96600C (fi) | 1987-02-25 | 1988-02-24 | Välituotteina käyttökelpoisia tetratsoliyhdisteitä |
Country Status (27)
Country | Link |
---|---|
US (1) | US4898949A (fi) |
JP (1) | JP2603284B2 (fi) |
KR (1) | KR960007167B1 (fi) |
CN (1) | CN1030077C (fi) |
AT (1) | AT395588B (fi) |
AU (1) | AU610562B2 (fi) |
BE (1) | BE1002115A3 (fi) |
CA (1) | CA1328269C (fi) |
CH (1) | CH678182A5 (fi) |
DE (1) | DE3805789C2 (fi) |
DK (2) | DK97388A (fi) |
ES (1) | ES2009547A6 (fi) |
FI (1) | FI96600C (fi) |
FR (1) | FR2611201B1 (fi) |
GB (1) | GB2202845B (fi) |
GR (1) | GR1000473B (fi) |
HU (3) | HU201534B (fi) |
IE (1) | IE61608B1 (fi) |
IT (1) | IT1216752B (fi) |
LU (1) | LU87143A1 (fi) |
MY (1) | MY102290A (fi) |
NL (1) | NL8800468A (fi) |
NO (1) | NO178432C (fi) |
NZ (1) | NZ223621A (fi) |
PT (1) | PT86821B (fi) |
SE (3) | SE504553C2 (fi) |
YU (1) | YU46781B (fi) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4870187A (en) * | 1988-08-23 | 1989-09-26 | Bristol-Myers Company | Antihypercholesterolemic tetrazol-1-yl compounds |
FI94339C (fi) | 1989-07-21 | 1995-08-25 | Warner Lambert Co | Menetelmä farmaseuttisesti käyttökelpoisen /R-(R*,R*)/-2-(4-fluorifenyyli)- , -dihydroksi-5-(1-metyylietyyli)-3-fenyyli-4-/(fenyyliamino)karbonyyli/-1H-pyrroli-1-heptaanihapon ja sen farmaseuttisesti hyväksyttävien suolojen valmistamiseksi |
US5260325A (en) * | 1991-08-19 | 1993-11-09 | E. I. Du Pont De Nemours And Company | Angiotensin II receptor blocking tertiary amides |
CA2137049A1 (en) * | 1993-12-15 | 1995-06-16 | John K. Thottathil | Amino acid salts of and methods for preparing antihypercholesterolemic tetrazole compounds |
IL135562A (en) * | 1997-12-19 | 2005-08-31 | Warner Lambert Exp Ltd | Process for the synthesis of cis-1,3-diols and a synergistic combination of trialkylborane and dialkylalkoxyborane for such synthesis |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4160100A (en) * | 1973-03-23 | 1979-07-03 | American Home Products Corporation | Oxamic acid derivatives |
US4013647A (en) * | 1976-03-23 | 1977-03-22 | American Home Products Corporation | Morpholine containing tetrazole-5-carboxamide derivatives |
JPS53147073A (en) * | 1977-05-24 | 1978-12-21 | Sankyo Co Ltd | Mevalonolactone derivatives |
US4375475A (en) * | 1979-08-17 | 1983-03-01 | Merck & Co., Inc. | Substituted pyranone inhibitors of cholesterol synthesis |
NZ194557A (en) * | 1979-08-17 | 1984-09-28 | Merck & Co Inc | Substituted pyranone derivatives;dihydroxy acids therefrom;pharmaceutical compositions |
US4567289A (en) * | 1979-08-17 | 1986-01-28 | Merck & Co., Inc. | Substituted pyranone inhibitors of cholesterol synthesis |
EP0068038B1 (en) * | 1981-06-29 | 1985-09-25 | Merck & Co. Inc. | (+)-(4r,6s)-(e)-6-(2-(4'-fluoro-3,3',5-trimethyl-(1,1'-biphenyl)-2-yl)ethenyl)-3,4,5,6-tetrahydro-4-hydroxy-2h-pyran-2-one, a process for preparing and a pharmaceutical composition containing the same |
US4739073A (en) * | 1983-11-04 | 1988-04-19 | Sandoz Pharmaceuticals Corp. | Intermediates in the synthesis of indole analogs of mevalonolactone and derivatives thereof |
WO1984002131A1 (en) * | 1982-11-22 | 1984-06-07 | Sandoz Ag | Analogs of mevalolactone and derivatives thereof, processes for their production, pharmaceutical compositions containing them and their use as pharmaceuticals |
ATE23326T1 (de) * | 1983-01-24 | 1986-11-15 | Sandoz Ag | Mevalonslakton-analoge und ihre derivate, verfahren zu ihrer herstellung, diese enthaltende pharmazeutische zusammensetzungen sowie deren verwendung als heilmittel. |
US5105017A (en) * | 1983-07-18 | 1992-04-14 | Eli Lilly And Company | Leukotriene antagonist intermediates |
CA1327360C (en) * | 1983-11-14 | 1994-03-01 | William F. Hoffman | Oxo-analogs of mevinolin-like antihypercholesterolemic agents |
US4613610A (en) * | 1984-06-22 | 1986-09-23 | Sandoz Pharmaceuticals Corp. | Cholesterol biosynthesis inhibiting pyrazole analogs of mevalonolactone and its derivatives |
DE3582674D1 (de) * | 1984-06-22 | 1991-05-29 | Sandoz Ag | Pyrazolanaloge von mevalonolakton und abkoemmlinge davon, verfahren zu deren herstellung und deren verwendung. |
US4668794A (en) * | 1985-05-22 | 1987-05-26 | Sandoz Pharm. Corp. | Intermediate imidazole acrolein analogs |
US4621099A (en) * | 1985-09-23 | 1986-11-04 | Usv Pharmaceutical Corporation | Polyene compounds useful in the treatment of allergic responses |
US4681893A (en) * | 1986-05-30 | 1987-07-21 | Warner-Lambert Company | Trans-6-[2-(3- or 4-carboxamido-substituted pyrrol-1-yl)alkyl]-4-hydroxypyran-2-one inhibitors of cholesterol synthesis |
US4678806A (en) * | 1986-09-02 | 1987-07-07 | Merck & Co., Inc. | Prodrugs of antihypercholesterolemic compounds |
AU601264B2 (en) * | 1987-02-25 | 1990-09-06 | Bristol-Myers Squibb Company | Antihypercholesterolemic tetrazole compounds |
-
1988
- 1988-02-18 US US07/151,512 patent/US4898949A/en not_active Expired - Lifetime
- 1988-02-24 HU HU895133A patent/HU201534B/hu not_active IP Right Cessation
- 1988-02-24 PT PT86821A patent/PT86821B/pt not_active IP Right Cessation
- 1988-02-24 JP JP63041828A patent/JP2603284B2/ja not_active Expired - Fee Related
- 1988-02-24 GR GR880100100A patent/GR1000473B/el not_active IP Right Cessation
- 1988-02-24 ES ES8800533A patent/ES2009547A6/es not_active Expired
- 1988-02-24 HU HU895124A patent/HU201533B/hu not_active IP Right Cessation
- 1988-02-24 SE SE8800637A patent/SE504553C2/sv not_active IP Right Cessation
- 1988-02-24 HU HU88885A patent/HU201532B/hu not_active IP Right Cessation
- 1988-02-24 AU AU12132/88A patent/AU610562B2/en not_active Ceased
- 1988-02-24 CA CA000559671A patent/CA1328269C/en not_active Expired - Fee Related
- 1988-02-24 GB GB8804281A patent/GB2202845B/en not_active Expired - Fee Related
- 1988-02-24 IT IT8819526A patent/IT1216752B/it active
- 1988-02-24 FI FI880868A patent/FI96600C/fi not_active IP Right Cessation
- 1988-02-24 KR KR1019880001915A patent/KR960007167B1/ko not_active IP Right Cessation
- 1988-02-24 CH CH691/88A patent/CH678182A5/de not_active IP Right Cessation
- 1988-02-24 DK DK097388A patent/DK97388A/da not_active Application Discontinuation
- 1988-02-24 MY MYPI88000180A patent/MY102290A/en unknown
- 1988-02-24 DE DE3805789A patent/DE3805789C2/de not_active Expired - Fee Related
- 1988-02-24 IE IE50288A patent/IE61608B1/en not_active IP Right Cessation
- 1988-02-24 NL NL8800468A patent/NL8800468A/nl not_active Application Discontinuation
- 1988-02-24 NZ NZ223621A patent/NZ223621A/en unknown
- 1988-02-24 NO NO880802A patent/NO178432C/no not_active IP Right Cessation
- 1988-02-24 AT AT0046088A patent/AT395588B/de not_active IP Right Cessation
- 1988-02-24 FR FR888802212A patent/FR2611201B1/fr not_active Expired - Fee Related
- 1988-02-25 LU LU87143A patent/LU87143A1/fr unknown
- 1988-02-25 YU YU36488A patent/YU46781B/sh unknown
- 1988-02-25 BE BE8800219A patent/BE1002115A3/fr not_active IP Right Cessation
-
1992
- 1992-10-20 CN CN92111551A patent/CN1030077C/zh not_active Expired - Fee Related
-
1993
- 1993-03-24 SE SE9300977A patent/SE512485C2/sv not_active IP Right Cessation
- 1993-03-24 SE SE9300976A patent/SE503201C2/sv not_active IP Right Cessation
-
1997
- 1997-10-06 DK DK113897A patent/DK113897A/da not_active Application Discontinuation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
BB | Publication of examined application | ||
FG | Patent granted |
Owner name: BRISTOL-MYERS SQUIBB COMPANY |
|
MA | Patent expired |