FI880868A - Välituotteina käyttökelpoisia tetratsoliyhdisteitä - Google Patents
Välituotteina käyttökelpoisia tetratsoliyhdisteitä Download PDFInfo
- Publication number
- FI880868A FI880868A FI880868A FI880868A FI880868A FI 880868 A FI880868 A FI 880868A FI 880868 A FI880868 A FI 880868A FI 880868 A FI880868 A FI 880868A FI 880868 A FI880868 A FI 880868A
- Authority
- FI
- Finland
- Prior art keywords
- intermediates
- compounds useful
- tetrazole compounds
- tetrazole
- useful
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D257/04—Five-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6524—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having four or more nitrogen atoms as the only ring hetero atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hematology (AREA)
- Pharmacology & Pharmacy (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FI931579A FI96953C (fi) | 1987-02-25 | 1993-04-07 | Tetratsolijohdannaisia ja menetelmä niiden valmistamiseksi |
FI931580A FI96602C (fi) | 1987-02-25 | 1993-04-07 | Menetelmä terapeuttisesti aktiivisten tetratsolijohdannaisten valmistamiseksi |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US1855887A | 1987-02-25 | 1987-02-25 | |
US1855887 | 1987-02-25 | ||
US07/151,512 US4898949A (en) | 1987-02-25 | 1988-02-18 | Intermediates for the preparation of antihypercholesterolemic tetrazole compounds |
US15151288 | 1988-02-18 |
Publications (4)
Publication Number | Publication Date |
---|---|
FI880868A0 FI880868A0 (fi) | 1988-02-24 |
FI880868A true FI880868A (fi) | 1988-08-26 |
FI96600B FI96600B (fi) | 1996-04-15 |
FI96600C FI96600C (fi) | 1996-07-25 |
Family
ID=26691250
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI880868A FI96600C (fi) | 1987-02-25 | 1988-02-24 | Välituotteina käyttökelpoisia tetratsoliyhdisteitä |
Country Status (27)
Country | Link |
---|---|
US (1) | US4898949A (fi) |
JP (1) | JP2603284B2 (fi) |
KR (1) | KR960007167B1 (fi) |
CN (1) | CN1030077C (fi) |
AT (1) | AT395588B (fi) |
AU (1) | AU610562B2 (fi) |
BE (1) | BE1002115A3 (fi) |
CA (1) | CA1328269C (fi) |
CH (1) | CH678182A5 (fi) |
DE (1) | DE3805789C2 (fi) |
DK (2) | DK97388A (fi) |
ES (1) | ES2009547A6 (fi) |
FI (1) | FI96600C (fi) |
FR (1) | FR2611201B1 (fi) |
GB (1) | GB2202845B (fi) |
GR (1) | GR1000473B (fi) |
HU (3) | HU201532B (fi) |
IE (1) | IE61608B1 (fi) |
IT (1) | IT1216752B (fi) |
LU (1) | LU87143A1 (fi) |
MY (1) | MY102290A (fi) |
NL (1) | NL8800468A (fi) |
NO (1) | NO178432C (fi) |
NZ (1) | NZ223621A (fi) |
PT (1) | PT86821B (fi) |
SE (3) | SE504553C2 (fi) |
YU (1) | YU46781B (fi) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4870187A (en) * | 1988-08-23 | 1989-09-26 | Bristol-Myers Company | Antihypercholesterolemic tetrazol-1-yl compounds |
FI94339C (fi) | 1989-07-21 | 1995-08-25 | Warner Lambert Co | Menetelmä farmaseuttisesti käyttökelpoisen /R-(R*,R*)/-2-(4-fluorifenyyli)- , -dihydroksi-5-(1-metyylietyyli)-3-fenyyli-4-/(fenyyliamino)karbonyyli/-1H-pyrroli-1-heptaanihapon ja sen farmaseuttisesti hyväksyttävien suolojen valmistamiseksi |
US5260325A (en) * | 1991-08-19 | 1993-11-09 | E. I. Du Pont De Nemours And Company | Angiotensin II receptor blocking tertiary amides |
CA2137049A1 (en) * | 1993-12-15 | 1995-06-16 | John K. Thottathil | Amino acid salts of and methods for preparing antihypercholesterolemic tetrazole compounds |
PT1054860E (pt) * | 1997-12-19 | 2007-06-22 | Pfizer Ireland Pharmaceuticals | Processo para a síntese 1, 2 dióis |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4160100A (en) * | 1973-03-23 | 1979-07-03 | American Home Products Corporation | Oxamic acid derivatives |
US4013647A (en) * | 1976-03-23 | 1977-03-22 | American Home Products Corporation | Morpholine containing tetrazole-5-carboxamide derivatives |
JPS53147073A (en) * | 1977-05-24 | 1978-12-21 | Sankyo Co Ltd | Mevalonolactone derivatives |
IL60751A (en) * | 1979-08-17 | 1985-04-30 | Merck & Co Inc | 6-(2'-((substituted phenyl)ethyl and-ethenyl)-4-hydroxy-tetrahydro-2h-pyran-2-one derivatives,their preparation and pharmaceutical compositions containing them |
US4567289A (en) * | 1979-08-17 | 1986-01-28 | Merck & Co., Inc. | Substituted pyranone inhibitors of cholesterol synthesis |
US4375475A (en) * | 1979-08-17 | 1983-03-01 | Merck & Co., Inc. | Substituted pyranone inhibitors of cholesterol synthesis |
EP0068038B1 (en) * | 1981-06-29 | 1985-09-25 | Merck & Co. Inc. | (+)-(4r,6s)-(e)-6-(2-(4'-fluoro-3,3',5-trimethyl-(1,1'-biphenyl)-2-yl)ethenyl)-3,4,5,6-tetrahydro-4-hydroxy-2h-pyran-2-one, a process for preparing and a pharmaceutical composition containing the same |
AU570021B2 (en) * | 1982-11-22 | 1988-03-03 | Novartis Ag | Analogs of mevalolactone |
US4739073A (en) * | 1983-11-04 | 1988-04-19 | Sandoz Pharmaceuticals Corp. | Intermediates in the synthesis of indole analogs of mevalonolactone and derivatives thereof |
DE3461180D1 (en) * | 1983-01-24 | 1986-12-11 | Sandoz Ag | Analogs of mevalonolactone and derivatives thereof, processes for their production, pharmaceutical compositions containing them and their use as pharmaceuticals |
US5105017A (en) * | 1983-07-18 | 1992-04-14 | Eli Lilly And Company | Leukotriene antagonist intermediates |
CA1327360C (en) * | 1983-11-14 | 1994-03-01 | William F. Hoffman | Oxo-analogs of mevinolin-like antihypercholesterolemic agents |
EP0200736B1 (en) * | 1984-06-22 | 1991-04-24 | Sandoz Ag | Pyrazole analogs of mevalonolactone and derivatives thereof, processes for their production and their use |
US4613610A (en) * | 1984-06-22 | 1986-09-23 | Sandoz Pharmaceuticals Corp. | Cholesterol biosynthesis inhibiting pyrazole analogs of mevalonolactone and its derivatives |
US4668794A (en) * | 1985-05-22 | 1987-05-26 | Sandoz Pharm. Corp. | Intermediate imidazole acrolein analogs |
US4621099A (en) * | 1985-09-23 | 1986-11-04 | Usv Pharmaceutical Corporation | Polyene compounds useful in the treatment of allergic responses |
US4681893A (en) * | 1986-05-30 | 1987-07-21 | Warner-Lambert Company | Trans-6-[2-(3- or 4-carboxamido-substituted pyrrol-1-yl)alkyl]-4-hydroxypyran-2-one inhibitors of cholesterol synthesis |
US4678806A (en) * | 1986-09-02 | 1987-07-07 | Merck & Co., Inc. | Prodrugs of antihypercholesterolemic compounds |
AU601264B2 (en) * | 1987-02-25 | 1990-09-06 | Bristol-Myers Squibb Company | Antihypercholesterolemic tetrazole compounds |
-
1988
- 1988-02-18 US US07/151,512 patent/US4898949A/en not_active Expired - Lifetime
- 1988-02-24 NO NO880802A patent/NO178432C/no not_active IP Right Cessation
- 1988-02-24 CA CA000559671A patent/CA1328269C/en not_active Expired - Fee Related
- 1988-02-24 JP JP63041828A patent/JP2603284B2/ja not_active Expired - Fee Related
- 1988-02-24 SE SE8800637A patent/SE504553C2/sv not_active IP Right Cessation
- 1988-02-24 AU AU12132/88A patent/AU610562B2/en not_active Ceased
- 1988-02-24 AT AT0046088A patent/AT395588B/de not_active IP Right Cessation
- 1988-02-24 NZ NZ223621A patent/NZ223621A/en unknown
- 1988-02-24 PT PT86821A patent/PT86821B/pt not_active IP Right Cessation
- 1988-02-24 KR KR1019880001915A patent/KR960007167B1/ko not_active IP Right Cessation
- 1988-02-24 HU HU88885A patent/HU201532B/hu not_active IP Right Cessation
- 1988-02-24 IE IE50288A patent/IE61608B1/en not_active IP Right Cessation
- 1988-02-24 FI FI880868A patent/FI96600C/fi not_active IP Right Cessation
- 1988-02-24 ES ES8800533A patent/ES2009547A6/es not_active Expired
- 1988-02-24 HU HU895133A patent/HU201534B/hu not_active IP Right Cessation
- 1988-02-24 DK DK097388A patent/DK97388A/da not_active Application Discontinuation
- 1988-02-24 NL NL8800468A patent/NL8800468A/nl not_active Application Discontinuation
- 1988-02-24 IT IT8819526A patent/IT1216752B/it active
- 1988-02-24 HU HU895124A patent/HU201533B/hu not_active IP Right Cessation
- 1988-02-24 FR FR888802212A patent/FR2611201B1/fr not_active Expired - Fee Related
- 1988-02-24 GR GR880100100A patent/GR1000473B/el not_active IP Right Cessation
- 1988-02-24 GB GB8804281A patent/GB2202845B/en not_active Expired - Fee Related
- 1988-02-24 CH CH691/88A patent/CH678182A5/de not_active IP Right Cessation
- 1988-02-24 MY MYPI88000180A patent/MY102290A/en unknown
- 1988-02-24 DE DE3805789A patent/DE3805789C2/de not_active Expired - Fee Related
- 1988-02-25 LU LU87143A patent/LU87143A1/fr unknown
- 1988-02-25 YU YU36488A patent/YU46781B/sh unknown
- 1988-02-25 BE BE8800219A patent/BE1002115A3/fr not_active IP Right Cessation
-
1992
- 1992-10-20 CN CN92111551A patent/CN1030077C/zh not_active Expired - Fee Related
-
1993
- 1993-03-24 SE SE9300977A patent/SE512485C2/sv not_active IP Right Cessation
- 1993-03-24 SE SE9300976A patent/SE503201C2/sv not_active IP Right Cessation
-
1997
- 1997-10-06 DK DK113897A patent/DK113897A/da not_active Application Discontinuation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
BB | Publication of examined application | ||
FG | Patent granted |
Owner name: BRISTOL-MYERS SQUIBB COMPANY |
|
MA | Patent expired |