NO178397C - Substituerte 1,2,3,4-tetrahydrocyklopent[bÅindoler, 1,2,3,3a,4,8a-heksahydrocyklopent[bÅindoler og beslektede forbindelser, mellomprodukter og deres bruk som medikamenter - Google Patents
Substituerte 1,2,3,4-tetrahydrocyklopent[bÅindoler, 1,2,3,3a,4,8a-heksahydrocyklopent[bÅindoler og beslektede forbindelser, mellomprodukter og deres bruk som medikamenterInfo
- Publication number
- NO178397C NO178397C NO920235A NO920235A NO178397C NO 178397 C NO178397 C NO 178397C NO 920235 A NO920235 A NO 920235A NO 920235 A NO920235 A NO 920235A NO 178397 C NO178397 C NO 178397C
- Authority
- NO
- Norway
- Prior art keywords
- indole
- intermediates
- tetrahydrocyclopentic
- hexahydrocyclopentic
- drugs
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Epidemiology (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/642,952 US5100891A (en) | 1991-01-18 | 1991-01-18 | Substituted 1,2,3,4-tetrahydrocyclopent[b]indoles, 1,2,3,3a,4,8a-hexahydrocyclopent[B]indoles and related compounds |
Publications (4)
Publication Number | Publication Date |
---|---|
NO920235D0 NO920235D0 (no) | 1992-01-17 |
NO920235L NO920235L (no) | 1992-07-20 |
NO178397B NO178397B (no) | 1995-12-11 |
NO178397C true NO178397C (no) | 1996-03-20 |
Family
ID=24578739
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO920235A NO178397C (no) | 1991-01-18 | 1992-01-17 | Substituerte 1,2,3,4-tetrahydrocyklopent[bÅindoler, 1,2,3,3a,4,8a-heksahydrocyklopent[bÅindoler og beslektede forbindelser, mellomprodukter og deres bruk som medikamenter |
Country Status (26)
Country | Link |
---|---|
US (1) | US5100891A (no) |
EP (1) | EP0496314B1 (no) |
JP (1) | JP2665422B2 (no) |
KR (1) | KR100230881B1 (no) |
AT (1) | ATE158790T1 (no) |
AU (1) | AU650315B2 (no) |
BR (1) | BR9200171A (no) |
CA (1) | CA2059610C (no) |
CZ (1) | CZ282732B6 (no) |
DE (1) | DE69222444T2 (no) |
DK (1) | DK0496314T3 (no) |
ES (1) | ES2109953T3 (no) |
FI (2) | FI102174B (no) |
GR (1) | GR3025318T3 (no) |
HU (1) | HUT67027A (no) |
IE (1) | IE920149A1 (no) |
IL (1) | IL100693A0 (no) |
MX (1) | MX9200206A (no) |
NO (1) | NO178397C (no) |
NZ (1) | NZ241305A (no) |
PH (1) | PH31429A (no) |
PL (2) | PL169417B1 (no) |
RO (1) | RO112505B1 (no) |
RU (1) | RU2077530C1 (no) |
TW (1) | TW198024B (no) |
ZA (1) | ZA92341B (no) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5298626A (en) * | 1991-01-18 | 1994-03-29 | Hoechst-Roussel Pharmaceuticals Incorporated | Select cyclopent[b]indoles |
US5350762A (en) * | 1993-03-08 | 1994-09-27 | Hoechst-Roussel Pharmaceuticals Incorporated | Tetrahydrocyclopent[B]indole methanamines and related compounds |
DE997458T1 (de) * | 1997-07-03 | 2001-03-01 | Asahi Chemical Ind | Tricyclische verbindungen mit gesättigten ringen und diese enthaltende medizinische zubereitungen |
UA70334C2 (en) * | 1998-10-06 | 2004-10-15 | Janssen Pharmaceutica N V Jans | BENZOTHIENO[3,2-c]PYRIDINES AS a2 ANTAGONISTS BENZOTHIENO[3,2-c]PYRIDINES AS a2 ANTAGONISTS |
UA69420C2 (uk) * | 1998-10-06 | 2004-09-15 | Янссен Фармацевтика Н.В. | ТРИЦИКЛІЧНІ <font face="Symbol">D3</font>-ПІПЕРИДИНИ ЯК <font face="Symbol">a<sub></font>2</sub>-АНТАГОНІСТИ |
DE69918148T2 (de) * | 1998-10-06 | 2005-07-28 | Janssen Pharmaceutica N.V. | Trizyclische delta3-pyridine als arzneimittel |
IT1317926B1 (it) * | 2000-11-03 | 2003-07-15 | Sigma Tau Ind Farmaceuti | Derivati triciclici dell'indolo ad attivita' antiangiogenica. |
US7351733B2 (en) | 2003-06-10 | 2008-04-01 | Smithkline Beecham Corporation | Tetrahydrocarbazole derivatives and their pharmaceutical use |
ES2327416T3 (es) * | 2003-06-12 | 2009-10-29 | Smithkline Beecham Corporation | Derivados de tetraidrocarbazol y su uso farmaceutico. |
CA2588389A1 (en) * | 2004-11-23 | 2006-06-22 | Ptc Therapeutics, Inc. | Substituted phenols as active agents inhibiting vegf production |
GB2422828A (en) * | 2005-02-03 | 2006-08-09 | Hunter Fleming Ltd | Tricyclic cytoprotective compounds comprising an indole residue |
WO2013139929A1 (en) * | 2012-03-22 | 2013-09-26 | Ludwig-Maximilians-Universität München | Novel means and methods for treating diseases of the central nervous system, metabolic and cardiac diseases and aging |
KR20140013471A (ko) | 2012-07-24 | 2014-02-05 | 주식회사 쎄코 | 진공증착용 발열조립체 및 이를 구비하는 진공증착장치 |
US10882821B1 (en) | 2017-09-26 | 2021-01-05 | The Board Of Trustees Of The Leland Stanford Junior University | Enantiomeric compound for the reduction of the deleterious activity of extended nucleotide repeat containing genes |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3514462A (en) * | 1966-10-21 | 1970-05-26 | Upjohn Co | 1 and 2 ethoxy 3,4,5,10 - tetrahydroazepino(3,4-b) and (2,3-b)indoles and corresponding amino derivatives thereof |
US3595874A (en) * | 1969-02-28 | 1971-07-27 | Upjohn Co | 3,4,5,10-tetrahydroazepino(2,3-b)indol-5a (2h)-ols |
BE787537A (fr) * | 1971-08-16 | 1973-02-14 | Sterling Drug Inc | Tetrahydrocarbazoles |
SU482086A1 (ru) * | 1973-11-30 | 1976-03-15 | Всесоюзный Научно-Исследовательски% Химико-Фармацевтический Институт Им.С.Орджоникидзе | Способ получени производных 1- -амино1,2,3,4-тетрагидрокарбазола |
FR2275202A1 (fr) * | 1974-06-18 | 1976-01-16 | Ayerst Mckenna & Harrison | Derives tricycliques d'alcoylamines et preparation de ceux-ci |
US4254134A (en) * | 1978-03-17 | 1981-03-03 | Endo Laboratories, Inc. | Antidepressant 2-amino- and -2-(substituted amino)-cis-hexahydro-carbazoles |
-
1991
- 1991-01-18 US US07/642,952 patent/US5100891A/en not_active Expired - Lifetime
-
1992
- 1992-01-15 NZ NZ241305A patent/NZ241305A/en unknown
- 1992-01-15 RO RO149168A patent/RO112505B1/ro unknown
- 1992-01-16 PL PL92293209A patent/PL169417B1/pl unknown
- 1992-01-16 PL PL92296651A patent/PL167465B1/pl unknown
- 1992-01-16 CZ CS92129A patent/CZ282732B6/cs not_active IP Right Cessation
- 1992-01-16 KR KR1019920000543A patent/KR100230881B1/ko not_active IP Right Cessation
- 1992-01-16 FI FI920192A patent/FI102174B/fi active
- 1992-01-17 NO NO920235A patent/NO178397C/no unknown
- 1992-01-17 IL IL100693A patent/IL100693A0/xx unknown
- 1992-01-17 MX MX9200206A patent/MX9200206A/es unknown
- 1992-01-17 AU AU10279/92A patent/AU650315B2/en not_active Ceased
- 1992-01-17 RU SU925010763A patent/RU2077530C1/ru active
- 1992-01-17 JP JP4006681A patent/JP2665422B2/ja not_active Expired - Lifetime
- 1992-01-17 ZA ZA92341A patent/ZA92341B/xx unknown
- 1992-01-17 IE IE014992A patent/IE920149A1/en not_active IP Right Cessation
- 1992-01-17 CA CA002059610A patent/CA2059610C/en not_active Expired - Lifetime
- 1992-01-17 HU HU9200172A patent/HUT67027A/hu unknown
- 1992-01-18 DK DK92100816.5T patent/DK0496314T3/da active
- 1992-01-18 EP EP92100816A patent/EP0496314B1/en not_active Expired - Lifetime
- 1992-01-18 DE DE69222444T patent/DE69222444T2/de not_active Expired - Lifetime
- 1992-01-18 ES ES92100816T patent/ES2109953T3/es not_active Expired - Lifetime
- 1992-01-18 AT AT92100816T patent/ATE158790T1/de not_active IP Right Cessation
- 1992-01-21 BR BR929200171A patent/BR9200171A/pt not_active Application Discontinuation
- 1992-02-20 TW TW081101228A patent/TW198024B/zh active
- 1992-11-20 PH PH43793A patent/PH31429A/en unknown
-
1997
- 1997-11-07 GR GR970402960T patent/GR3025318T3/el unknown
-
2000
- 2000-08-10 FI FI20001775A patent/FI107919B/fi active
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