BR9200171A - Compostos e processos para a sua preparacao,composicao farmaceutica e usos dos ditos compostos - Google Patents

Compostos e processos para a sua preparacao,composicao farmaceutica e usos dos ditos compostos

Info

Publication number
BR9200171A
BR9200171A BR929200171A BR9200171A BR9200171A BR 9200171 A BR9200171 A BR 9200171A BR 929200171 A BR929200171 A BR 929200171A BR 9200171 A BR9200171 A BR 9200171A BR 9200171 A BR9200171 A BR 9200171A
Authority
BR
Brazil
Prior art keywords
compounds
preparation
processes
pharmaceutical composition
useful
Prior art date
Application number
BR929200171A
Other languages
English (en)
Inventor
Helen Hu Ong
Gerard Joseph O'malley
Michael Clayton Merriman
Mark Gabriel Palermo
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of BR9200171A publication Critical patent/BR9200171A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Epidemiology (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
BR929200171A 1991-01-18 1992-01-21 Compostos e processos para a sua preparacao,composicao farmaceutica e usos dos ditos compostos BR9200171A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/642,952 US5100891A (en) 1991-01-18 1991-01-18 Substituted 1,2,3,4-tetrahydrocyclopent[b]indoles, 1,2,3,3a,4,8a-hexahydrocyclopent[B]indoles and related compounds

Publications (1)

Publication Number Publication Date
BR9200171A true BR9200171A (pt) 1992-10-06

Family

ID=24578739

Family Applications (1)

Application Number Title Priority Date Filing Date
BR929200171A BR9200171A (pt) 1991-01-18 1992-01-21 Compostos e processos para a sua preparacao,composicao farmaceutica e usos dos ditos compostos

Country Status (26)

Country Link
US (1) US5100891A (pt)
EP (1) EP0496314B1 (pt)
JP (1) JP2665422B2 (pt)
KR (1) KR100230881B1 (pt)
AT (1) ATE158790T1 (pt)
AU (1) AU650315B2 (pt)
BR (1) BR9200171A (pt)
CA (1) CA2059610C (pt)
CZ (1) CZ282732B6 (pt)
DE (1) DE69222444T2 (pt)
DK (1) DK0496314T3 (pt)
ES (1) ES2109953T3 (pt)
FI (2) FI102174B1 (pt)
GR (1) GR3025318T3 (pt)
HU (1) HUT67027A (pt)
IE (1) IE920149A1 (pt)
IL (1) IL100693A0 (pt)
MX (1) MX9200206A (pt)
NO (1) NO178397C (pt)
NZ (1) NZ241305A (pt)
PH (1) PH31429A (pt)
PL (2) PL167465B1 (pt)
RO (1) RO112505B1 (pt)
RU (1) RU2077530C1 (pt)
TW (1) TW198024B (pt)
ZA (1) ZA92341B (pt)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5298626A (en) * 1991-01-18 1994-03-29 Hoechst-Roussel Pharmaceuticals Incorporated Select cyclopent[b]indoles
US5350762A (en) * 1993-03-08 1994-09-27 Hoechst-Roussel Pharmaceuticals Incorporated Tetrahydrocyclopent[B]indole methanamines and related compounds
ES2149742T1 (es) * 1997-07-03 2000-11-16 Asahi Chemical Ind Nuevos compuestos triciclicos que tienen anillos saturados y composiciones medicinales que contienen los mismos.
IL142444A0 (en) * 1998-10-06 2002-03-10 Janssen Pharmaceutica Nv TRICYCLIC δ3-PIPERIDINES AS PHARMACEUTICALS
UA69420C2 (uk) * 1998-10-06 2004-09-15 Янссен Фармацевтика Н.В. ТРИЦИКЛІЧНІ <font face="Symbol">D3</font>-ПІПЕРИДИНИ ЯК <font face="Symbol">a<sub></font>2</sub>-АНТАГОНІСТИ
UA70334C2 (en) * 1998-10-06 2004-10-15 Janssen Pharmaceutica N V Jans BENZOTHIENO[3,2-c]PYRIDINES AS a2 ANTAGONISTS BENZOTHIENO[3,2-c]PYRIDINES AS a2 ANTAGONISTS
IT1317926B1 (it) 2000-11-03 2003-07-15 Sigma Tau Ind Farmaceuti Derivati triciclici dell'indolo ad attivita' antiangiogenica.
ES2314446T3 (es) 2003-06-10 2009-03-16 Smithkline Beecham Corporation Derivados de tetrahidrocarbazol y su uso farmaceutico.
CA2528336A1 (en) 2003-06-12 2005-01-20 Smithkline Beecham Corporation Tetrahydrocarbazole derivatives and their pharmaceutical use
MX2007006178A (es) * 2004-11-23 2007-06-20 Ptc Therapeutics Inc Fenoles substituidos como agentes activos que inhiben la produccion del factor de crecimiento endotelial vascular.
GB2422828A (en) * 2005-02-03 2006-08-09 Hunter Fleming Ltd Tricyclic cytoprotective compounds comprising an indole residue
WO2013139929A1 (en) * 2012-03-22 2013-09-26 Ludwig-Maximilians-Universität München Novel means and methods for treating diseases of the central nervous system, metabolic and cardiac diseases and aging
KR20140013471A (ko) 2012-07-24 2014-02-05 주식회사 쎄코 진공증착용 발열조립체 및 이를 구비하는 진공증착장치
US10882821B1 (en) 2017-09-26 2021-01-05 The Board Of Trustees Of The Leland Stanford Junior University Enantiomeric compound for the reduction of the deleterious activity of extended nucleotide repeat containing genes

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3514462A (en) * 1966-10-21 1970-05-26 Upjohn Co 1 and 2 ethoxy 3,4,5,10 - tetrahydroazepino(3,4-b) and (2,3-b)indoles and corresponding amino derivatives thereof
US3595874A (en) * 1969-02-28 1971-07-27 Upjohn Co 3,4,5,10-tetrahydroazepino(2,3-b)indol-5a (2h)-ols
BE787537A (fr) * 1971-08-16 1973-02-14 Sterling Drug Inc Tetrahydrocarbazoles
SU482086A1 (ru) * 1973-11-30 1976-03-15 Всесоюзный Научно-Исследовательски% Химико-Фармацевтический Институт Им.С.Орджоникидзе Способ получени производных 1- -амино1,2,3,4-тетрагидрокарбазола
JPS5111760A (pt) * 1974-06-18 1976-01-30 Ayerst Mckenna & Harrison
US4254134A (en) * 1978-03-17 1981-03-03 Endo Laboratories, Inc. Antidepressant 2-amino- and -2-(substituted amino)-cis-hexahydro-carbazoles

Also Published As

Publication number Publication date
FI107919B (fi) 2001-10-31
HU9200172D0 (en) 1992-04-28
FI920192A0 (fi) 1992-01-16
ZA92341B (en) 1992-09-30
PL169417B1 (pl) 1996-07-31
KR100230881B1 (ko) 1999-11-15
NO178397C (no) 1996-03-20
KR920014777A (ko) 1992-08-25
IL100693A0 (en) 1992-09-06
NO920235D0 (no) 1992-01-17
PL167465B1 (pl) 1995-09-30
DE69222444T2 (de) 1998-06-04
CA2059610C (en) 2002-04-02
MX9200206A (es) 1992-08-01
US5100891A (en) 1992-03-31
RO112505B1 (ro) 1997-10-30
CA2059610A1 (en) 1992-07-19
FI20001775A (fi) 2000-08-10
DK0496314T3 (da) 1998-05-18
AU1027992A (en) 1992-07-23
FI920192A (fi) 1992-07-19
ATE158790T1 (de) 1997-10-15
NO178397B (no) 1995-12-11
CZ282732B6 (cs) 1997-09-17
JP2665422B2 (ja) 1997-10-22
EP0496314B1 (en) 1997-10-01
FI102174B (fi) 1998-10-30
NO920235L (no) 1992-07-20
PH31429A (en) 1998-11-03
RU2077530C1 (ru) 1997-04-20
TW198024B (pt) 1993-01-11
JPH04334367A (ja) 1992-11-20
NZ241305A (en) 1994-10-26
HUT67027A (en) 1995-01-30
ES2109953T3 (es) 1998-02-01
PL293209A1 (en) 1993-04-05
PL296651A1 (en) 1993-07-26
EP0496314A1 (en) 1992-07-29
IE920149A1 (en) 1992-07-29
DE69222444D1 (de) 1997-11-06
CS12992A3 (en) 1992-08-12
FI102174B1 (fi) 1998-10-30
GR3025318T3 (en) 1998-02-27
AU650315B2 (en) 1994-06-16

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Legal Events

Date Code Title Description
EG Technical examination (opinion): publication of technical examination (opinion)
PC Transfer

Free format text: HOECHST MARION ROUSSEL, INC. (US)

FC Decision: refusal