FI920192A0 - Substituerade 1,2,3,4-tetrahydro -cyklopent/b/indoler, 1,2,3,3a,4,8a-hexahydrocyklopent/b/indoler och motsvarande foereningar, mellanprodukter och foerfarande foer deras framstaellning och deras anvaendning som laekemedel. - Google Patents
Substituerade 1,2,3,4-tetrahydro -cyklopent/b/indoler, 1,2,3,3a,4,8a-hexahydrocyklopent/b/indoler och motsvarande foereningar, mellanprodukter och foerfarande foer deras framstaellning och deras anvaendning som laekemedel.Info
- Publication number
- FI920192A0 FI920192A0 FI920192A FI920192A FI920192A0 FI 920192 A0 FI920192 A0 FI 920192A0 FI 920192 A FI920192 A FI 920192A FI 920192 A FI920192 A FI 920192A FI 920192 A0 FI920192 A0 FI 920192A0
- Authority
- FI
- Finland
- Prior art keywords
- indoler
- hexahydrocyklopent
- substituerade
- cyclopent
- tetrahydro
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Psychiatry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FI970397A FI106713B (fi) | 1991-01-18 | 1997-01-30 | Substituoituja 1,4-dihydrosyklopent[b]indol-3(2H)-onijohdannaisia |
FI970396A FI107150B (fi) | 1991-01-18 | 1997-01-30 | Menetelmä terapeuttisesti aktiivisten iminosubstituoitujen syklopent[b]indolijohdannaisten valmistamiseksi |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US64295291 | 1991-01-18 | ||
US07/642,952 US5100891A (en) | 1991-01-18 | 1991-01-18 | Substituted 1,2,3,4-tetrahydrocyclopent[b]indoles, 1,2,3,3a,4,8a-hexahydrocyclopent[B]indoles and related compounds |
Publications (4)
Publication Number | Publication Date |
---|---|
FI920192A0 true FI920192A0 (fi) | 1992-01-16 |
FI920192A FI920192A (fi) | 1992-07-19 |
FI102174B1 FI102174B1 (fi) | 1998-10-30 |
FI102174B FI102174B (fi) | 1998-10-30 |
Family
ID=24578739
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI920192A FI102174B (fi) | 1991-01-18 | 1992-01-16 | Menetelmä 1,2,3,4-tetrahydro- ja 1,2,3,3a,4,8b-heksahydrosyklopent£b|i ndolijohdannaisten valmistamiseksi |
FI20001775A FI107919B (fi) | 1991-01-18 | 2000-08-10 | Välituotteina käyttökelpoisia iminosubstituoituja syklopent[b]indolijohdannaisia |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI20001775A FI107919B (fi) | 1991-01-18 | 2000-08-10 | Välituotteina käyttökelpoisia iminosubstituoituja syklopent[b]indolijohdannaisia |
Country Status (26)
Country | Link |
---|---|
US (1) | US5100891A (fi) |
EP (1) | EP0496314B1 (fi) |
JP (1) | JP2665422B2 (fi) |
KR (1) | KR100230881B1 (fi) |
AT (1) | ATE158790T1 (fi) |
AU (1) | AU650315B2 (fi) |
BR (1) | BR9200171A (fi) |
CA (1) | CA2059610C (fi) |
CZ (1) | CZ282732B6 (fi) |
DE (1) | DE69222444T2 (fi) |
DK (1) | DK0496314T3 (fi) |
ES (1) | ES2109953T3 (fi) |
FI (2) | FI102174B (fi) |
GR (1) | GR3025318T3 (fi) |
HU (1) | HUT67027A (fi) |
IE (1) | IE920149A1 (fi) |
IL (1) | IL100693A0 (fi) |
MX (1) | MX9200206A (fi) |
NO (1) | NO178397C (fi) |
NZ (1) | NZ241305A (fi) |
PH (1) | PH31429A (fi) |
PL (2) | PL169417B1 (fi) |
RO (1) | RO112505B1 (fi) |
RU (1) | RU2077530C1 (fi) |
TW (1) | TW198024B (fi) |
ZA (1) | ZA92341B (fi) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5298626A (en) * | 1991-01-18 | 1994-03-29 | Hoechst-Roussel Pharmaceuticals Incorporated | Select cyclopent[b]indoles |
US5350762A (en) * | 1993-03-08 | 1994-09-27 | Hoechst-Roussel Pharmaceuticals Incorporated | Tetrahydrocyclopent[B]indole methanamines and related compounds |
ES2149742T1 (es) * | 1997-07-03 | 2000-11-16 | Asahi Chemical Ind | Nuevos compuestos triciclicos que tienen anillos saturados y composiciones medicinales que contienen los mismos. |
UA70961C2 (uk) * | 1998-10-06 | 2004-11-15 | Янссен Фармацевтика Н.В. | ТРИЦИКЛІЧНІ <font face="Symbol">D</font>3-ПІПЕРИДИНИ, КОМПОЗИЦІЯ НА ЇХ ОСНОВІ ТА СПОСІБ ЇХ ОДЕРЖАННЯ (ВАРІАНТИ) |
UA70334C2 (en) * | 1998-10-06 | 2004-10-15 | Janssen Pharmaceutica N V Jans | BENZOTHIENO[3,2-c]PYRIDINES AS a2 ANTAGONISTS BENZOTHIENO[3,2-c]PYRIDINES AS a2 ANTAGONISTS |
UA69420C2 (uk) * | 1998-10-06 | 2004-09-15 | Янссен Фармацевтика Н.В. | ТРИЦИКЛІЧНІ <font face="Symbol">D3</font>-ПІПЕРИДИНИ ЯК <font face="Symbol">a<sub></font>2</sub>-АНТАГОНІСТИ |
IT1317926B1 (it) * | 2000-11-03 | 2003-07-15 | Sigma Tau Ind Farmaceuti | Derivati triciclici dell'indolo ad attivita' antiangiogenica. |
DE602004017326D1 (de) | 2003-06-10 | 2008-12-04 | Smithkline Beecham Corp | Tetrahydrocarbazolderivate und deren pharmazeutische verwendung |
EP1646610B1 (en) * | 2003-06-12 | 2009-07-22 | SmithKline Beecham Corporation | Tetrahydrocarbazole derivatives and their pharmaceutical use |
CA2588384A1 (en) * | 2004-11-23 | 2006-06-22 | Ptc Therapeutics, Inc. | Tetrahydrocarbazoles as active agents for inhibiting vegf production by translational control |
GB2422828A (en) * | 2005-02-03 | 2006-08-09 | Hunter Fleming Ltd | Tricyclic cytoprotective compounds comprising an indole residue |
WO2013139929A1 (en) * | 2012-03-22 | 2013-09-26 | Ludwig-Maximilians-Universität München | Novel means and methods for treating diseases of the central nervous system, metabolic and cardiac diseases and aging |
KR20140013471A (ko) | 2012-07-24 | 2014-02-05 | 주식회사 쎄코 | 진공증착용 발열조립체 및 이를 구비하는 진공증착장치 |
US10882821B1 (en) | 2017-09-26 | 2021-01-05 | The Board Of Trustees Of The Leland Stanford Junior University | Enantiomeric compound for the reduction of the deleterious activity of extended nucleotide repeat containing genes |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3514462A (en) * | 1966-10-21 | 1970-05-26 | Upjohn Co | 1 and 2 ethoxy 3,4,5,10 - tetrahydroazepino(3,4-b) and (2,3-b)indoles and corresponding amino derivatives thereof |
US3595874A (en) * | 1969-02-28 | 1971-07-27 | Upjohn Co | 3,4,5,10-tetrahydroazepino(2,3-b)indol-5a (2h)-ols |
BE787537A (fr) * | 1971-08-16 | 1973-02-14 | Sterling Drug Inc | Tetrahydrocarbazoles |
SU482086A1 (ru) * | 1973-11-30 | 1976-03-15 | Всесоюзный Научно-Исследовательски% Химико-Фармацевтический Институт Им.С.Орджоникидзе | Способ получени производных 1- -амино1,2,3,4-тетрагидрокарбазола |
FR2275202A1 (fr) * | 1974-06-18 | 1976-01-16 | Ayerst Mckenna & Harrison | Derives tricycliques d'alcoylamines et preparation de ceux-ci |
US4254134A (en) * | 1978-03-17 | 1981-03-03 | Endo Laboratories, Inc. | Antidepressant 2-amino- and -2-(substituted amino)-cis-hexahydro-carbazoles |
-
1991
- 1991-01-18 US US07/642,952 patent/US5100891A/en not_active Expired - Lifetime
-
1992
- 1992-01-15 RO RO149168A patent/RO112505B1/ro unknown
- 1992-01-15 NZ NZ241305A patent/NZ241305A/en unknown
- 1992-01-16 FI FI920192A patent/FI102174B/fi active
- 1992-01-16 PL PL92293209A patent/PL169417B1/pl unknown
- 1992-01-16 PL PL92296651A patent/PL167465B1/pl unknown
- 1992-01-16 CZ CS92129A patent/CZ282732B6/cs not_active IP Right Cessation
- 1992-01-16 KR KR1019920000543A patent/KR100230881B1/ko not_active IP Right Cessation
- 1992-01-17 IL IL100693A patent/IL100693A0/xx unknown
- 1992-01-17 HU HU9200172A patent/HUT67027A/hu unknown
- 1992-01-17 JP JP4006681A patent/JP2665422B2/ja not_active Expired - Lifetime
- 1992-01-17 MX MX9200206A patent/MX9200206A/es unknown
- 1992-01-17 RU SU925010763A patent/RU2077530C1/ru active
- 1992-01-17 CA CA002059610A patent/CA2059610C/en not_active Expired - Lifetime
- 1992-01-17 ZA ZA92341A patent/ZA92341B/xx unknown
- 1992-01-17 AU AU10279/92A patent/AU650315B2/en not_active Ceased
- 1992-01-17 IE IE014992A patent/IE920149A1/en not_active IP Right Cessation
- 1992-01-17 NO NO920235A patent/NO178397C/no unknown
- 1992-01-18 DE DE69222444T patent/DE69222444T2/de not_active Expired - Lifetime
- 1992-01-18 AT AT92100816T patent/ATE158790T1/de not_active IP Right Cessation
- 1992-01-18 EP EP92100816A patent/EP0496314B1/en not_active Expired - Lifetime
- 1992-01-18 ES ES92100816T patent/ES2109953T3/es not_active Expired - Lifetime
- 1992-01-18 DK DK92100816.5T patent/DK0496314T3/da active
- 1992-01-21 BR BR929200171A patent/BR9200171A/pt not_active Application Discontinuation
- 1992-02-20 TW TW081101228A patent/TW198024B/zh active
- 1992-11-20 PH PH43793A patent/PH31429A/en unknown
-
1997
- 1997-11-07 GR GR970402960T patent/GR3025318T3/el unknown
-
2000
- 2000-08-10 FI FI20001775A patent/FI107919B/fi active
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
GB | Transfer or assigment of application |
Owner name: HOECHST MARION ROUSSEL, INC. |