DK0614888T3 - Tetrahydrocyclopentab indol-methanaminer og beslægtede forbindelser, en fremgangsmåde til deres fremstilling og deres anvendelse som lægemidler. - Google Patents

Tetrahydrocyclopentab indol-methanaminer og beslægtede forbindelser, en fremgangsmåde til deres fremstilling og deres anvendelse som lægemidler.

Info

Publication number
DK0614888T3
DK0614888T3 DK94102993.6T DK94102993T DK0614888T3 DK 0614888 T3 DK0614888 T3 DK 0614888T3 DK 94102993 T DK94102993 T DK 94102993T DK 0614888 T3 DK0614888 T3 DK 0614888T3
Authority
DK
Denmark
Prior art keywords
tetrahydrocyclopentab
methanamines
indole
drugs
preparation
Prior art date
Application number
DK94102993.6T
Other languages
English (en)
Inventor
Lawrence Leo Martin
Larry Davis
Original Assignee
Hoechst Marion Roussel Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel Inc
Application granted granted Critical
Publication of DK0614888T3 publication Critical patent/DK0614888T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/58—[b]- or [c]-condensed
    • C07D209/62—Naphtho [c] pyrroles; Hydrogenated naphtho [c] pyrroles
    • C07D209/64—Naphtho [c] pyrroles; Hydrogenated naphtho [c] pyrroles with an oxygen atom in position 1
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Psychiatry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK94102993.6T 1993-03-08 1994-02-28 Tetrahydrocyclopentab indol-methanaminer og beslægtede forbindelser, en fremgangsmåde til deres fremstilling og deres anvendelse som lægemidler. DK0614888T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/028,110 US5350762A (en) 1993-03-08 1993-03-08 Tetrahydrocyclopent[B]indole methanamines and related compounds

Publications (1)

Publication Number Publication Date
DK0614888T3 true DK0614888T3 (da) 1997-11-03

Family

ID=21841633

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94102993.6T DK0614888T3 (da) 1993-03-08 1994-02-28 Tetrahydrocyclopentab indol-methanaminer og beslægtede forbindelser, en fremgangsmåde til deres fremstilling og deres anvendelse som lægemidler.

Country Status (9)

Country Link
US (1) US5350762A (da)
EP (1) EP0614888B1 (da)
JP (1) JP2749259B2 (da)
AT (1) ATE152709T1 (da)
CA (1) CA2117164A1 (da)
DE (1) DE69403015T2 (da)
DK (1) DK0614888T3 (da)
ES (1) ES2101373T3 (da)
GR (1) GR3024187T3 (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5756743A (en) 1996-04-10 1998-05-26 Hoechst Marion Roussel Inc. Spiro cyclopent b!indole-piperidines!
US5665880A (en) * 1996-10-31 1997-09-09 Hoechst Marion Roussel, Inc. Method of preparation of physostigmine carbamate derivatives from eseretholes
US6251938B1 (en) 1996-12-18 2001-06-26 Teva Pharmaceutical Industries, Ltd., Phenylethylamine derivatives
CA2275425C (en) 1996-12-18 2009-08-04 Michael Chorev Aminoindan derivatives
US5677457A (en) * 1996-12-19 1997-10-14 Hoechst Marion Roussel, Inc. Method of preparation of physostigmine carbamate derivatives from eseroline ethers
IT1317926B1 (it) * 2000-11-03 2003-07-15 Sigma Tau Ind Farmaceuti Derivati triciclici dell'indolo ad attivita' antiangiogenica.
AU2006326642B2 (en) 2005-12-09 2012-05-03 Technion Research And Development Foundation Ltd. Use of low-dose ladostigil for neuroprotection
TW200744576A (en) 2006-02-24 2007-12-16 Teva Pharma Propargylated aminoindans, processes for preparation, and uses thereof
DK2051962T3 (da) * 2006-08-07 2012-01-02 Actelion Pharmaceuticals Ltd (3-amino-1,2,3,4-tetrahydro-9H-carbazol-9-yl)-eddikesyrederivater

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE757404A (da) * 1969-10-13 1971-04-13 Sandoz Sa
BE793493A (fr) * 1971-12-30 1973-06-29 Hoffmann La Roche Composes tricycliques
US4009181A (en) * 1973-01-22 1977-02-22 Hoffmann-La Roche Inc. Cyclopenta[b]indole-2-carboxylic acids and derivatives thereof
FR2275202A1 (fr) * 1974-06-18 1976-01-16 Ayerst Mckenna & Harrison Derives tricycliques d'alcoylamines et preparation de ceux-ci
JPS5283736A (en) * 1976-01-01 1977-07-12 Ayerst Mckenna & Harrison Tricyclic alkylamine derivatives
US4235903A (en) * 1979-08-06 1980-11-25 American Home Products Corporation 1-Hydroxyalkanamine tetrahydrocarbazoles and cyclopent[b]indoles, compositions and method of use
US5100891A (en) * 1991-01-18 1992-03-31 Hoechst-Roussel Pharmaceuticals Inc. Substituted 1,2,3,4-tetrahydrocyclopent[b]indoles, 1,2,3,3a,4,8a-hexahydrocyclopent[B]indoles and related compounds

Also Published As

Publication number Publication date
DE69403015D1 (de) 1997-06-12
ES2101373T3 (es) 1997-07-01
GR3024187T3 (en) 1997-10-31
CA2117164A1 (en) 1994-09-09
EP0614888A1 (en) 1994-09-14
JP2749259B2 (ja) 1998-05-13
EP0614888B1 (en) 1997-05-07
JPH06321898A (ja) 1994-11-22
DE69403015T2 (de) 1997-10-09
ATE152709T1 (de) 1997-05-15
US5350762A (en) 1994-09-27

Similar Documents

Publication Publication Date Title
CY1110745T1 (el) Παραγωγα πυρρολιδονης ως αναστολεις μαοβ
NO992821L (no) Ketobenzamider som calpain-inhibitorer
RS53704A (en) Alpha-(n-sulphonamido)acetamide derivatives as betha- amyloid inhibitors
FI961809A0 (fi) Uudet (R)-5-karbamoyyli-8-fluori-3-N,N-disubstituoitu-amino 3,4-dihydro-2H-1-bentsopyraanit
ES2188584T3 (es) Derivados heterociclicos de amina.
PT1263730E (pt) Derivados amina para o tratamento de apoptose
NO941937L (no) Sakarinderivater som inhiberer proteolytiske enzymer
ATE248837T1 (de) Chinuclidin-acrylamide
NO20054787D0 (no) Indenderivater som farmasotiske midler
PT669920E (pt) 3-aminoalquilamino-1,2-benzoxazoles substituidos ecompostos relacionados
DK0404283T3 (da) 11alfa-aryl-4-estrener, fremgangsmåde til fremstilling af disse samt deres anvendelse som lægemidler
MX9804226A (es) Derivados novedosos de 2,3,5-trimetil-4-hidroxianilida, su preparacion y su aplicacion de terapeutica.
YU29300A (sh) Katalizovane reakcije prelaznog metala bazirane na hiralnim amin oksazolinil ligandima
DK0614888T3 (da) Tetrahydrocyclopentab indol-methanaminer og beslægtede forbindelser, en fremgangsmåde til deres fremstilling og deres anvendelse som lægemidler.
DK0649846T3 (da) Galanthaminderivater, en fremgangsmåde til deres fremstilling og deres anvendelse som lægemidler
NO178397C (no) Substituerte 1,2,3,4-tetrahydrocyklopent[bÅindoler, 1,2,3,3a,4,8a-heksahydrocyklopent[bÅindoler og beslektede forbindelser, mellomprodukter og deres bruk som medikamenter
DK0632026T3 (da) Alfa-aminosyrederivater, en fremgangsmåde til deres fremstilling og farmaceutiske sammensætninger, der indeholder dem
PT870761E (pt) Derivados de tiocolchicina com actividades anti-inflamatoria e relaxante muscular
DK0998471T3 (da) Heterocykliske forbindelser, fremgangsmåde til fremstilling heraf og farmaceutiske sammensætninger, som indeholder disse
BR9707004A (pt) Composto processo para preparar o mesmo composição farmacêutica utilização do composto e processos para tratamento de doenças do sistema endocinológico e para a manufatura de um medicamento
GEP19991780B (en) Use of Pyrrolidine Derivatives for Treating Alcoholism
DK0703232T3 (da) 2,3-Dihydro-1H-isoindolderivater, fremgangsmåde til deres fremstilling og deres anvendelse som hæmmere af serotoningenoptagelsen
DK0709378T3 (da) Aminoalkyloximer, en fremgangsmåde til deres fremstilling, deres anvendelse som lægemidler og mellemproduktforbindelser
DK0627432T3 (da) 6-Piperazinyl-1H-pyrazolo(3,4-b)pyridin-3-carboxylsyrer, deres estere, amider og beslægtede forbindelser, en fremgangsmåde til deres fremstilling og deres anvendelse som lægemidler
BG105247A (en) N-substituted azabicycloheptane derivatives, production and use thereof