DK0709378T3 - Aminoalkyloximer, en fremgangsmåde til deres fremstilling, deres anvendelse som lægemidler og mellemproduktforbindelser - Google Patents
Aminoalkyloximer, en fremgangsmåde til deres fremstilling, deres anvendelse som lægemidler og mellemproduktforbindelserInfo
- Publication number
- DK0709378T3 DK0709378T3 DK95111895T DK95111895T DK0709378T3 DK 0709378 T3 DK0709378 T3 DK 0709378T3 DK 95111895 T DK95111895 T DK 95111895T DK 95111895 T DK95111895 T DK 95111895T DK 0709378 T3 DK0709378 T3 DK 0709378T3
- Authority
- DK
- Denmark
- Prior art keywords
- preparation
- aminoalkyloxymes
- drugs
- intermediate compounds
- aminoalkyloxines
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
- C07D211/14—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/30—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom
- C07D211/32—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/285,668 US5665756A (en) | 1994-08-03 | 1994-08-03 | Aminoalkyloximes useful in the treatment of depression and obsessive compulsive disorders |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0709378T3 true DK0709378T3 (da) | 2003-07-14 |
Family
ID=23095223
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK95111895T DK0709378T3 (da) | 1994-08-03 | 1995-07-28 | Aminoalkyloximer, en fremgangsmåde til deres fremstilling, deres anvendelse som lægemidler og mellemproduktforbindelser |
Country Status (9)
Country | Link |
---|---|
US (8) | US5665756A (da) |
EP (1) | EP0709378B1 (da) |
JP (1) | JP3947238B2 (da) |
AT (1) | ATE234820T1 (da) |
CA (1) | CA2155275C (da) |
DE (1) | DE69529958T2 (da) |
DK (1) | DK0709378T3 (da) |
ES (1) | ES2194033T3 (da) |
PT (1) | PT709378E (da) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2670236C (en) * | 1999-09-30 | 2012-06-05 | Hollis-Eden Pharmaceuticals, Inc. | Therapeutic treatment of androgen receptor driven conditions |
DE19952146A1 (de) * | 1999-10-29 | 2001-06-07 | Boehringer Ingelheim Pharma | Arylalkane, Arylalkene und Aryl-azaalkane, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung |
US7256191B2 (en) * | 2000-04-24 | 2007-08-14 | Aryx Therapeutics | Materials and methods for the treatment of depression |
JP2003531169A (ja) | 2000-04-24 | 2003-10-21 | アリックス セラピューティクス | うつ病治療のための材料と方法 |
US8193768B2 (en) * | 2008-02-28 | 2012-06-05 | Jason S. Hallett | Contactless charging system for musical instruments |
US11498903B2 (en) | 2017-08-17 | 2022-11-15 | Bristol-Myers Squibb Company | 2-(1,1′-biphenyl)-1H-benzodimidazole derivatives and related compounds as apelin and APJ agonists for treating cardiovascular diseases |
Family Cites Families (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3692835A (en) * | 1967-04-05 | 1972-09-19 | Jan Van Dijk | Pharmacologically active amino-ethyl oximes |
BE759128R (fr) * | 1969-11-18 | 1971-05-18 | Usv Pharma Corp | Carbamoyl oximes et leur methode de |
FR2162312B1 (da) * | 1971-12-10 | 1975-02-07 | Buzas Andre | |
FR2215953B2 (da) * | 1973-02-05 | 1976-05-14 | Buzas Andre | |
US4192893A (en) * | 1975-03-20 | 1980-03-11 | U.S. Philips Corporation | Anti-depressive compounds |
NL7503313A (en) * | 1975-03-20 | 1976-09-22 | Philips Nv | Antiaggressive oxime ethers - viz 4-nitro-2-butyl(oxy)-acetophenone O-aminoalkyl-oximes |
NL7503310A (nl) * | 1975-03-20 | 1976-09-22 | Philips Nv | Verbindingen met antidepressieve werking. |
NL7610399A (en) * | 1976-09-20 | 1978-03-22 | Philips Nv | O-Aminoethyl oxime derivs. of halophenyl ketone cpds. - are selective nor-adrenalin potentiators useful as antidepressants |
GR61620B (en) * | 1976-10-14 | 1978-12-04 | Byk Gulden Lomberg Chem Fab | Preparation process of pyrazol-1-yl-phenyloxic acids |
DE2658762A1 (de) * | 1976-12-24 | 1978-06-29 | Hoechst Ag | Neue o-alkylierte oxime, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
DE2658938A1 (de) * | 1976-12-24 | 1978-07-06 | Hoechst Ag | Neue basisch substituierte 0-propyloxime, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
US4297359A (en) * | 1978-07-25 | 1981-10-27 | Acf Chemiefarma Nv | Anti-ulcer compositions containing certain pyridyl oxime ethers |
US4352804A (en) * | 1978-07-25 | 1982-10-05 | Acf Chemiefarma Nv | Oxime ethers, their preparation and pharmaceutical compositions containing them |
AU532700B2 (en) * | 1979-04-02 | 1983-10-13 | Sumitomo Chemical Company, Limited | Diphenylalkanoether |
DE3019497A1 (de) * | 1980-05-22 | 1981-11-26 | Bayer Ag, 5090 Leverkusen | Aminopropiophenon-derivate, verfahren zu ihrer herstellung und ihre verwendung als fungizide |
WO1981003579A1 (en) * | 1980-06-07 | 1981-12-10 | Hell R Gmbh | High stability electron gun for the shaping of materials |
EP0053017B1 (en) * | 1980-11-24 | 1985-02-20 | Imperial Chemical Industries Plc | Amide derivatives |
US4851423A (en) * | 1986-12-10 | 1989-07-25 | Schering Corporation | Pharmaceutically active compounds |
JPS6463574A (en) * | 1987-09-03 | 1989-03-09 | Mitsubishi Chem Ind | Ethanone oximes |
GB8811056D0 (en) * | 1988-05-10 | 1988-06-15 | Ici Plc | Antibiotic compounds |
HU207988B (en) * | 1988-10-20 | 1993-07-28 | Biorex Kutato Fejlesztoe Kft | Process for producing halogenides of o-/3-amino-2-hydroxy-propyl/hydroximic acid and pharmaceutical compositions containing them as active components |
DE3927483A1 (de) * | 1989-08-19 | 1991-02-21 | Boehringer Ingelheim Kg | Neue substituierte heterocyclische fuenfringe, ihre herstellung und verwendung |
IL97144A (en) * | 1990-02-27 | 1994-11-28 | Erba Carlo Spa | History of 1-) Alkoxy-Iminoalkyl (Imidazole Transformed Preparation and Pharmaceutical Preparations Containing Them |
-
1994
- 1994-08-03 US US08/285,668 patent/US5665756A/en not_active Expired - Lifetime
-
1995
- 1995-06-01 US US08/457,681 patent/US5686446A/en not_active Expired - Lifetime
- 1995-06-01 US US08/457,422 patent/US5686483A/en not_active Expired - Lifetime
- 1995-06-01 US US08/457,259 patent/US5684021A/en not_active Expired - Lifetime
- 1995-06-01 US US08/458,147 patent/US5686447A/en not_active Expired - Lifetime
- 1995-06-01 US US08/456,969 patent/US5696142A/en not_active Expired - Lifetime
- 1995-06-01 US US08/457,081 patent/US5648367A/en not_active Expired - Lifetime
- 1995-07-28 EP EP95111895A patent/EP0709378B1/en not_active Expired - Lifetime
- 1995-07-28 DE DE69529958T patent/DE69529958T2/de not_active Expired - Fee Related
- 1995-07-28 AT AT95111895T patent/ATE234820T1/de not_active IP Right Cessation
- 1995-07-28 DK DK95111895T patent/DK0709378T3/da active
- 1995-07-28 PT PT95111895T patent/PT709378E/pt unknown
- 1995-07-28 ES ES95111895T patent/ES2194033T3/es not_active Expired - Lifetime
- 1995-08-02 JP JP19720995A patent/JP3947238B2/ja not_active Expired - Fee Related
- 1995-08-02 CA CA002155275A patent/CA2155275C/en not_active Expired - Fee Related
-
1997
- 1997-07-29 US US08/902,462 patent/US5770740A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
US5648367A (en) | 1997-07-15 |
US5696142A (en) | 1997-12-09 |
PT709378E (pt) | 2003-06-30 |
JPH0859617A (ja) | 1996-03-05 |
US5665756A (en) | 1997-09-09 |
ES2194033T3 (es) | 2003-11-16 |
US5686483A (en) | 1997-11-11 |
US5686447A (en) | 1997-11-11 |
EP0709378A2 (en) | 1996-05-01 |
ATE234820T1 (de) | 2003-04-15 |
EP0709378A3 (en) | 1996-10-02 |
CA2155275A1 (en) | 1996-02-04 |
US5686446A (en) | 1997-11-11 |
JP3947238B2 (ja) | 2007-07-18 |
US5684021A (en) | 1997-11-04 |
US5770740A (en) | 1998-06-23 |
EP0709378B1 (en) | 2003-03-19 |
CA2155275C (en) | 2007-05-15 |
DE69529958D1 (de) | 2003-04-24 |
DE69529958T2 (de) | 2004-01-08 |
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