DK0401779T3 - 4,5,5a,6-Tetrahydro-3H-isoazolo(5,4,3-kl)acridinderivater, en fremgangsmåde til deres fremstilling og deres anvendelse som lægemidler - Google Patents
4,5,5a,6-Tetrahydro-3H-isoazolo(5,4,3-kl)acridinderivater, en fremgangsmåde til deres fremstilling og deres anvendelse som lægemidlerInfo
- Publication number
- DK0401779T3 DK0401779T3 DK90110684.9T DK90110684T DK0401779T3 DK 0401779 T3 DK0401779 T3 DK 0401779T3 DK 90110684 T DK90110684 T DK 90110684T DK 0401779 T3 DK0401779 T3 DK 0401779T3
- Authority
- DK
- Denmark
- Prior art keywords
- chem
- loweralkyl
- isoazolo
- tetrahydro
- pharmaceuticals
- Prior art date
Links
- 125000000641 acridinyl group Chemical class C1(=CC=CC2=NC3=CC=CC=C3C=C12)* 0.000 title 1
- 229940027998 antiseptic and disinfectant acridine derivative Drugs 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 150000002431 hydrogen Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 abstract 1
- 208000024827 Alzheimer disease Diseases 0.000 abstract 1
- 239000000730 antalgic agent Substances 0.000 abstract 1
- 230000006949 cholinergic function Effects 0.000 abstract 1
- 230000003247 decreasing effect Effects 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- -1 loweralkyl Chemical group 0.000 abstract 1
- 230000007074 memory dysfunction Effects 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/06—Peri-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Steroid Compounds (AREA)
- Liquid Crystal Substances (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/364,420 US4920117A (en) | 1989-06-09 | 1989-06-09 | 4,5,5a,6-tetrahydro-3H-isoxazolo(5,4,3-kl)acridines, pharmaceutical compositions and use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0401779T3 true DK0401779T3 (da) | 1995-10-16 |
Family
ID=23434459
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK90110684.9T DK0401779T3 (da) | 1989-06-09 | 1990-06-06 | 4,5,5a,6-Tetrahydro-3H-isoazolo(5,4,3-kl)acridinderivater, en fremgangsmåde til deres fremstilling og deres anvendelse som lægemidler |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US4920117A (da) |
| EP (1) | EP0401779B1 (da) |
| JP (1) | JPH089624B2 (da) |
| KR (1) | KR0148365B1 (da) |
| AT (1) | ATE122047T1 (da) |
| AU (1) | AU619985B2 (da) |
| CA (1) | CA2018564C (da) |
| DE (1) | DE69019066T2 (da) |
| DK (1) | DK0401779T3 (da) |
| ES (1) | ES2072334T3 (da) |
| FI (1) | FI902851A7 (da) |
| IE (1) | IE67074B1 (da) |
| IL (1) | IL94664A (da) |
| NO (1) | NO902556L (da) |
| NZ (1) | NZ233971A (da) |
| PT (1) | PT94298B (da) |
| ZA (1) | ZA904442B (da) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4927820A (en) * | 1988-11-25 | 1990-05-22 | Hoechst Roussel Pharmaceuticals Inc. | Fused heterocyclic derivatives of 1,2,3,4-tetrahydroacridine |
| US5236930A (en) * | 1989-11-13 | 1993-08-17 | Mitbushi Gas Chemical Company, Inc. | Oxazopyrroloquinolines and use of oxazopyrroloquinolines |
| EP1484325B1 (en) * | 2002-03-08 | 2014-06-18 | Japan Science and Technology Agency | Isoxazole derivatives and process for producing the same |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8314391D0 (en) * | 1983-05-24 | 1983-06-29 | Kefalas As | Heterocyclic compounds |
| FR2566407B1 (fr) * | 1984-06-25 | 1986-09-26 | Roussel Uclaf | Nouveaux derives de l'isoxazoloquinoleine, procede de preparation, application a titre de medicaments, et compositions les renfermant |
| US4927820A (en) * | 1988-11-25 | 1990-05-22 | Hoechst Roussel Pharmaceuticals Inc. | Fused heterocyclic derivatives of 1,2,3,4-tetrahydroacridine |
-
1989
- 1989-06-09 US US07/364,420 patent/US4920117A/en not_active Expired - Fee Related
-
1990
- 1990-06-06 EP EP90110684A patent/EP0401779B1/en not_active Expired - Lifetime
- 1990-06-06 DK DK90110684.9T patent/DK0401779T3/da active
- 1990-06-06 ES ES90110684T patent/ES2072334T3/es not_active Expired - Lifetime
- 1990-06-06 DE DE69019066T patent/DE69019066T2/de not_active Expired - Fee Related
- 1990-06-06 AT AT90110684T patent/ATE122047T1/de not_active IP Right Cessation
- 1990-06-07 NZ NZ233971A patent/NZ233971A/en unknown
- 1990-06-07 FI FI902851A patent/FI902851A7/fi not_active Application Discontinuation
- 1990-06-07 PT PT94298A patent/PT94298B/pt not_active IP Right Cessation
- 1990-06-07 IL IL9466490A patent/IL94664A/en not_active IP Right Cessation
- 1990-06-08 AU AU56917/90A patent/AU619985B2/en not_active Ceased
- 1990-06-08 KR KR1019900008392A patent/KR0148365B1/ko not_active Expired - Fee Related
- 1990-06-08 NO NO90902556A patent/NO902556L/no unknown
- 1990-06-08 CA CA002018564A patent/CA2018564C/en not_active Expired - Fee Related
- 1990-06-08 IE IE207890A patent/IE67074B1/en not_active IP Right Cessation
- 1990-06-08 JP JP2148885A patent/JPH089624B2/ja not_active Expired - Fee Related
- 1990-06-08 ZA ZA904442A patent/ZA904442B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU619985B2 (en) | 1992-02-06 |
| FI902851A0 (fi) | 1990-06-07 |
| JPH089624B2 (ja) | 1996-01-31 |
| FI902851A7 (fi) | 1990-12-10 |
| DE69019066D1 (de) | 1995-06-08 |
| KR0148365B1 (ko) | 1998-11-02 |
| IL94664A0 (en) | 1991-04-15 |
| US4920117A (en) | 1990-04-24 |
| ATE122047T1 (de) | 1995-05-15 |
| ES2072334T3 (es) | 1995-07-16 |
| IE67074B1 (en) | 1996-02-21 |
| JPH0324085A (ja) | 1991-02-01 |
| CA2018564C (en) | 2002-11-12 |
| KR910000744A (ko) | 1991-01-30 |
| DE69019066T2 (de) | 1995-10-19 |
| NZ233971A (en) | 1992-11-25 |
| PT94298A (pt) | 1991-02-08 |
| PT94298B (pt) | 1997-01-31 |
| CA2018564A1 (en) | 1990-12-09 |
| IL94664A (en) | 1994-11-11 |
| EP0401779B1 (en) | 1995-05-03 |
| NO902556D0 (no) | 1990-06-08 |
| NO902556L (no) | 1990-12-10 |
| ZA904442B (en) | 1991-03-27 |
| EP0401779A1 (en) | 1990-12-12 |
| IE902078L (en) | 1990-12-09 |
| AU5691790A (en) | 1990-12-13 |
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