DK0405342T3 - (1,2,3,4-Tetrahydro-9-acridinimino)cyclohexancarboxylsyre og beslægtede forbindelser, en fremgangsmåde til deres fremstilling og deres anvendelse som lægemidler - Google Patents
(1,2,3,4-Tetrahydro-9-acridinimino)cyclohexancarboxylsyre og beslægtede forbindelser, en fremgangsmåde til deres fremstilling og deres anvendelse som lægemidlerInfo
- Publication number
- DK0405342T3 DK0405342T3 DK90111814.1T DK90111814T DK0405342T3 DK 0405342 T3 DK0405342 T3 DK 0405342T3 DK 90111814 T DK90111814 T DK 90111814T DK 0405342 T3 DK0405342 T3 DK 0405342T3
- Authority
- DK
- Denmark
- Prior art keywords
- acridinimino
- tetrahydro
- drugs
- preparation
- related compounds
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 3
- NZNMSOFKMUBTKW-UHFFFAOYSA-N cyclohexanecarboxylic acid Chemical compound OC(=O)C1CCCCC1 NZNMSOFKMUBTKW-UHFFFAOYSA-N 0.000 title 2
- VZFUCHSFHOYXIS-UHFFFAOYSA-N cycloheptane carboxylic acid Natural products OC(=O)C1CCCCCC1 VZFUCHSFHOYXIS-UHFFFAOYSA-N 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 239000001257 hydrogen Substances 0.000 abstract 4
- 150000002431 hydrogen Chemical group 0.000 abstract 3
- 208000024827 Alzheimer disease Diseases 0.000 abstract 1
- 230000006949 cholinergic function Effects 0.000 abstract 1
- 230000003247 decreasing effect Effects 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 230000007074 memory dysfunction Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
- C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
- C07D219/08—Nitrogen atoms
- C07D219/10—Nitrogen atoms attached in position 9
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Pyridine Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/371,228 US4999358A (en) | 1989-06-26 | 1989-06-26 | (1,2,3,4-tetrahydro-9-acridinimino)cyclohexane carboxylic acid and related compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0405342T3 true DK0405342T3 (da) | 1995-05-15 |
Family
ID=23463058
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK90111814.1T DK0405342T3 (da) | 1989-06-26 | 1990-06-22 | (1,2,3,4-Tetrahydro-9-acridinimino)cyclohexancarboxylsyre og beslægtede forbindelser, en fremgangsmåde til deres fremstilling og deres anvendelse som lægemidler |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US4999358A (da) |
| EP (1) | EP0405342B1 (da) |
| JP (1) | JP2600013B2 (da) |
| KR (1) | KR0163186B1 (da) |
| AT (1) | ATE115133T1 (da) |
| AU (1) | AU625221B2 (da) |
| CA (1) | CA2019717C (da) |
| DE (1) | DE69014730T2 (da) |
| DK (1) | DK0405342T3 (da) |
| ES (1) | ES2064533T3 (da) |
| FI (1) | FI96307C (da) |
| IE (1) | IE65462B1 (da) |
| IL (3) | IL107001A (da) |
| NO (1) | NO177053C (da) |
| NZ (1) | NZ234199A (da) |
| PT (1) | PT94472B (da) |
| ZA (1) | ZA904914B (da) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2640508B1 (fr) * | 1988-12-19 | 1994-07-01 | Dietlin Francois | Nouvelles compositions et nouveaux produits pharmaceutiques assurant la regeneration de leucocytes et leur emploi pour le traitement du syndrome immuno-deficitaire |
| US5149813A (en) * | 1989-06-26 | 1992-09-22 | Hoechst-Roussel Pharmaceuticals Incorporated | Process for (1,2,3,4-tetrahydro-9-acridinimino)cyclohexane carboxylic acid and related compounds |
| US6100276A (en) * | 1996-04-12 | 2000-08-08 | Aventis Pharmaceuticals Inc. | Isatin derivatives as acetylcholinesterase inhibitors and analgesics |
| US5968517A (en) * | 1996-05-23 | 1999-10-19 | Duncan; Kelvin Winston | Process for extraction of proanthocyanidins from botanical material |
| EP1891954A3 (en) | 1998-09-30 | 2009-01-14 | Takeda Pharmaceutical Company Limited | Acetylcholinesterase inhibitors for improving excretory potency of urinary bladder |
| US8328939B2 (en) * | 2004-05-12 | 2012-12-11 | Applied Materials, Inc. | Diffuser plate with slit valve compensation |
| WO2012154879A2 (en) * | 2011-05-09 | 2012-11-15 | Van Andel Research Institute | Autophagy inhibitors |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB595603A (en) * | 1944-08-21 | 1947-12-10 | Ward Blenkinsop & Co Ltd | Process for the production of arylamino acridine derivatives |
| EP0268871A1 (en) * | 1986-10-31 | 1988-06-01 | Sumitomo Pharmaceuticals Company, Limited | Quinoline derivatives |
| US4851536A (en) * | 1987-05-07 | 1989-07-25 | American Home Products Corporation | Cyclohexylquinolines as inhibitors of interleukin 1 |
| EP0306826A1 (en) * | 1987-09-08 | 1989-03-15 | Hoechst-Roussel Pharmaceuticals Incorporated | N-(substituted alkylidene)fused bicycloalkylidene and hetero-alkylidene quinolinamines, a process for their preparation and their use as medicaments |
| IL87861A0 (en) * | 1987-10-05 | 1989-03-31 | Pfizer | 4-aminopyridine derivatives |
-
1989
- 1989-06-26 US US07/371,228 patent/US4999358A/en not_active Expired - Fee Related
-
1990
- 1990-06-22 AT AT90111814T patent/ATE115133T1/de not_active IP Right Cessation
- 1990-06-22 DE DE69014730T patent/DE69014730T2/de not_active Expired - Fee Related
- 1990-06-22 ES ES90111814T patent/ES2064533T3/es not_active Expired - Lifetime
- 1990-06-22 NZ NZ234199A patent/NZ234199A/en unknown
- 1990-06-22 EP EP90111814A patent/EP0405342B1/en not_active Expired - Lifetime
- 1990-06-22 DK DK90111814.1T patent/DK0405342T3/da active
- 1990-06-24 IL IL10700190A patent/IL107001A/en not_active IP Right Cessation
- 1990-06-24 IL IL9485490A patent/IL94854A/en not_active IP Right Cessation
- 1990-06-25 KR KR1019900009374A patent/KR0163186B1/ko not_active Expired - Fee Related
- 1990-06-25 AU AU57753/90A patent/AU625221B2/en not_active Ceased
- 1990-06-25 PT PT94472A patent/PT94472B/pt not_active IP Right Cessation
- 1990-06-25 IE IE229090A patent/IE65462B1/en not_active IP Right Cessation
- 1990-06-25 CA CA002019717A patent/CA2019717C/en not_active Expired - Fee Related
- 1990-06-25 FI FI903181A patent/FI96307C/fi active IP Right Grant
- 1990-06-25 ZA ZA904914A patent/ZA904914B/xx unknown
- 1990-06-25 NO NO902813A patent/NO177053C/no not_active IP Right Cessation
- 1990-06-25 JP JP2164371A patent/JP2600013B2/ja not_active Expired - Fee Related
-
1993
- 1993-09-14 IL IL107001A patent/IL107001A0/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2064533T3 (es) | 1995-02-01 |
| IL94854A0 (en) | 1991-04-15 |
| PT94472B (pt) | 1997-05-28 |
| FI96307B (fi) | 1996-02-29 |
| DE69014730T2 (de) | 1995-05-11 |
| CA2019717C (en) | 2001-01-23 |
| ATE115133T1 (de) | 1994-12-15 |
| DE69014730D1 (de) | 1995-01-19 |
| FI96307C (fi) | 1996-06-10 |
| JPH0395161A (ja) | 1991-04-19 |
| IL94854A (en) | 1994-08-26 |
| IE902290L (en) | 1990-12-26 |
| PT94472A (pt) | 1991-02-08 |
| NO902813L (no) | 1990-12-27 |
| KR0163186B1 (ko) | 1998-12-01 |
| AU5775390A (en) | 1991-01-03 |
| AU625221B2 (en) | 1992-07-02 |
| KR910000652A (ko) | 1991-01-29 |
| IL107001A0 (en) | 1993-12-28 |
| IL107001A (en) | 1994-10-21 |
| CA2019717A1 (en) | 1990-12-26 |
| ZA904914B (en) | 1992-02-26 |
| US4999358A (en) | 1991-03-12 |
| JP2600013B2 (ja) | 1997-04-16 |
| NO902813D0 (no) | 1990-06-25 |
| NO177053C (no) | 1995-07-12 |
| EP0405342A1 (en) | 1991-01-02 |
| NO177053B (no) | 1995-04-03 |
| EP0405342B1 (en) | 1994-12-07 |
| IE65462B1 (en) | 1995-11-01 |
| IE902290A1 (en) | 1991-01-16 |
| FI903181A0 (fi) | 1990-06-25 |
| NZ234199A (en) | 1992-05-26 |
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