ATE115133T1 - (1,2,3,4-tetrahydro-9-acridinimino)cyclohexan- carbonsäure und verwandte verbindungen, ein verfahren zu ihrer herstellung und ihre verwendung als medikamente. - Google Patents

(1,2,3,4-tetrahydro-9-acridinimino)cyclohexan- carbonsäure und verwandte verbindungen, ein verfahren zu ihrer herstellung und ihre verwendung als medikamente.

Info

Publication number
ATE115133T1
ATE115133T1 AT90111814T AT90111814T ATE115133T1 AT E115133 T1 ATE115133 T1 AT E115133T1 AT 90111814 T AT90111814 T AT 90111814T AT 90111814 T AT90111814 T AT 90111814T AT E115133 T1 ATE115133 T1 AT E115133T1
Authority
AT
Austria
Prior art keywords
acridinimino
medications
tetrahydro
preparation
carbonic acid
Prior art date
Application number
AT90111814T
Other languages
English (en)
Inventor
Lawrence Leo Martin
Joseph Francis Payack
Helen Hu Ong
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Application granted granted Critical
Publication of ATE115133T1 publication Critical patent/ATE115133T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C07D219/08—Nitrogen atoms
    • C07D219/10—Nitrogen atoms attached in position 9

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Psychiatry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT90111814T 1989-06-26 1990-06-22 (1,2,3,4-tetrahydro-9-acridinimino)cyclohexan- carbonsäure und verwandte verbindungen, ein verfahren zu ihrer herstellung und ihre verwendung als medikamente. ATE115133T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/371,228 US4999358A (en) 1989-06-26 1989-06-26 (1,2,3,4-tetrahydro-9-acridinimino)cyclohexane carboxylic acid and related compounds

Publications (1)

Publication Number Publication Date
ATE115133T1 true ATE115133T1 (de) 1994-12-15

Family

ID=23463058

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90111814T ATE115133T1 (de) 1989-06-26 1990-06-22 (1,2,3,4-tetrahydro-9-acridinimino)cyclohexan- carbonsäure und verwandte verbindungen, ein verfahren zu ihrer herstellung und ihre verwendung als medikamente.

Country Status (17)

Country Link
US (1) US4999358A (de)
EP (1) EP0405342B1 (de)
JP (1) JP2600013B2 (de)
KR (1) KR0163186B1 (de)
AT (1) ATE115133T1 (de)
AU (1) AU625221B2 (de)
CA (1) CA2019717C (de)
DE (1) DE69014730T2 (de)
DK (1) DK0405342T3 (de)
ES (1) ES2064533T3 (de)
FI (1) FI96307C (de)
IE (1) IE65462B1 (de)
IL (3) IL94854A (de)
NO (1) NO177053C (de)
NZ (1) NZ234199A (de)
PT (1) PT94472B (de)
ZA (1) ZA904914B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2640508B1 (fr) * 1988-12-19 1994-07-01 Dietlin Francois Nouvelles compositions et nouveaux produits pharmaceutiques assurant la regeneration de leucocytes et leur emploi pour le traitement du syndrome immuno-deficitaire
US5149813A (en) * 1989-06-26 1992-09-22 Hoechst-Roussel Pharmaceuticals Incorporated Process for (1,2,3,4-tetrahydro-9-acridinimino)cyclohexane carboxylic acid and related compounds
US6100276A (en) * 1996-04-12 2000-08-08 Aventis Pharmaceuticals Inc. Isatin derivatives as acetylcholinesterase inhibitors and analgesics
US5968517A (en) * 1996-05-23 1999-10-19 Duncan; Kelvin Winston Process for extraction of proanthocyanidins from botanical material
CN1535682A (zh) 1998-09-30 2004-10-13 ����ҩƷ��ҵ��ʽ���� 改善膀胱排泄能力的药物
US8328939B2 (en) * 2004-05-12 2012-12-11 Applied Materials, Inc. Diffuser plate with slit valve compensation
WO2012154879A2 (en) * 2011-05-09 2012-11-15 Van Andel Research Institute Autophagy inhibitors

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB595603A (en) * 1944-08-21 1947-12-10 Ward Blenkinsop & Co Ltd Process for the production of arylamino acridine derivatives
DK569087A (da) * 1986-10-31 1988-05-01 Sumitomo Pharma Quinolin-derivater, deres fremstilling og anvendelse
US4851536A (en) * 1987-05-07 1989-07-25 American Home Products Corporation Cyclohexylquinolines as inhibitors of interleukin 1
EP0306826A1 (de) * 1987-09-08 1989-03-15 Hoechst-Roussel Pharmaceuticals Incorporated N-(substituierte alkyliden) kondensierte Bicycloalkyliden- und Heteroalkyliden-Chinolinamine, Verfahren zu deren Herstellung und deren Verwendung als Medikamente
IL87861A0 (en) * 1987-10-05 1989-03-31 Pfizer 4-aminopyridine derivatives

Also Published As

Publication number Publication date
CA2019717A1 (en) 1990-12-26
IE902290A1 (en) 1991-01-16
IE902290L (en) 1990-12-26
DE69014730D1 (de) 1995-01-19
IL94854A (en) 1994-08-26
EP0405342A1 (de) 1991-01-02
FI96307B (fi) 1996-02-29
ZA904914B (en) 1992-02-26
IL107001A (en) 1994-10-21
ES2064533T3 (es) 1995-02-01
FI903181A0 (fi) 1990-06-25
KR910000652A (ko) 1991-01-29
JP2600013B2 (ja) 1997-04-16
NO177053C (no) 1995-07-12
EP0405342B1 (de) 1994-12-07
DE69014730T2 (de) 1995-05-11
KR0163186B1 (ko) 1998-12-01
IL94854A0 (en) 1991-04-15
NO902813L (no) 1990-12-27
NZ234199A (en) 1992-05-26
US4999358A (en) 1991-03-12
AU625221B2 (en) 1992-07-02
CA2019717C (en) 2001-01-23
IL107001A0 (en) 1993-12-28
PT94472B (pt) 1997-05-28
JPH0395161A (ja) 1991-04-19
FI96307C (fi) 1996-06-10
DK0405342T3 (da) 1995-05-15
NO177053B (no) 1995-04-03
NO902813D0 (no) 1990-06-25
IE65462B1 (en) 1995-11-01
AU5775390A (en) 1991-01-03
PT94472A (pt) 1991-02-08

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee