ATE122047T1 - 4,5,5a,6-tetrahydro-3h-isoxyzolo(5,4,3- k1)acridinderivate, ein verfahren zu ihrer herstellung und ihre verwendung als medikamente. - Google Patents

4,5,5a,6-tetrahydro-3h-isoxyzolo(5,4,3- k1)acridinderivate, ein verfahren zu ihrer herstellung und ihre verwendung als medikamente.

Info

Publication number
ATE122047T1
ATE122047T1 AT90110684T AT90110684T ATE122047T1 AT E122047 T1 ATE122047 T1 AT E122047T1 AT 90110684 T AT90110684 T AT 90110684T AT 90110684 T AT90110684 T AT 90110684T AT E122047 T1 ATE122047 T1 AT E122047T1
Authority
AT
Austria
Prior art keywords
chem
loweralkyl
isoxyzolo
medications
tetrahydro
Prior art date
Application number
AT90110684T
Other languages
English (en)
Inventor
Gregory Michael Shutske
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Application granted granted Critical
Publication of ATE122047T1 publication Critical patent/ATE122047T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Liquid Crystal Substances (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT90110684T 1989-06-09 1990-06-06 4,5,5a,6-tetrahydro-3h-isoxyzolo(5,4,3- k1)acridinderivate, ein verfahren zu ihrer herstellung und ihre verwendung als medikamente. ATE122047T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/364,420 US4920117A (en) 1989-06-09 1989-06-09 4,5,5a,6-tetrahydro-3H-isoxazolo(5,4,3-kl)acridines, pharmaceutical compositions and use

Publications (1)

Publication Number Publication Date
ATE122047T1 true ATE122047T1 (de) 1995-05-15

Family

ID=23434459

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90110684T ATE122047T1 (de) 1989-06-09 1990-06-06 4,5,5a,6-tetrahydro-3h-isoxyzolo(5,4,3- k1)acridinderivate, ein verfahren zu ihrer herstellung und ihre verwendung als medikamente.

Country Status (17)

Country Link
US (1) US4920117A (de)
EP (1) EP0401779B1 (de)
JP (1) JPH089624B2 (de)
KR (1) KR0148365B1 (de)
AT (1) ATE122047T1 (de)
AU (1) AU619985B2 (de)
CA (1) CA2018564C (de)
DE (1) DE69019066T2 (de)
DK (1) DK0401779T3 (de)
ES (1) ES2072334T3 (de)
FI (1) FI902851A0 (de)
IE (1) IE67074B1 (de)
IL (1) IL94664A (de)
NO (1) NO902556L (de)
NZ (1) NZ233971A (de)
PT (1) PT94298B (de)
ZA (1) ZA904442B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4927820A (en) * 1988-11-25 1990-05-22 Hoechst Roussel Pharmaceuticals Inc. Fused heterocyclic derivatives of 1,2,3,4-tetrahydroacridine
US5236930A (en) * 1989-11-13 1993-08-17 Mitbushi Gas Chemical Company, Inc. Oxazopyrroloquinolines and use of oxazopyrroloquinolines
EP1484325B1 (de) * 2002-03-08 2014-06-18 Japan Science and Technology Agency Isoxazolderivate und verfahren zu deren herstellung

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8314391D0 (en) * 1983-05-24 1983-06-29 Kefalas As Heterocyclic compounds
FR2566407B1 (fr) * 1984-06-25 1986-09-26 Roussel Uclaf Nouveaux derives de l'isoxazoloquinoleine, procede de preparation, application a titre de medicaments, et compositions les renfermant
US4927820A (en) * 1988-11-25 1990-05-22 Hoechst Roussel Pharmaceuticals Inc. Fused heterocyclic derivatives of 1,2,3,4-tetrahydroacridine

Also Published As

Publication number Publication date
DE69019066D1 (de) 1995-06-08
ZA904442B (en) 1991-03-27
AU619985B2 (en) 1992-02-06
JPH089624B2 (ja) 1996-01-31
IE902078L (en) 1990-12-09
US4920117A (en) 1990-04-24
IE67074B1 (en) 1996-02-21
JPH0324085A (ja) 1991-02-01
DE69019066T2 (de) 1995-10-19
EP0401779A1 (de) 1990-12-12
IL94664A (en) 1994-11-11
FI902851A0 (fi) 1990-06-07
DK0401779T3 (da) 1995-10-16
PT94298B (pt) 1997-01-31
ES2072334T3 (es) 1995-07-16
NO902556D0 (no) 1990-06-08
PT94298A (pt) 1991-02-08
NO902556L (no) 1990-12-10
AU5691790A (en) 1990-12-13
NZ233971A (en) 1992-11-25
IL94664A0 (en) 1991-04-15
EP0401779B1 (de) 1995-05-03
CA2018564A1 (en) 1990-12-09
CA2018564C (en) 2002-11-12
KR0148365B1 (ko) 1998-11-02
KR910000744A (ko) 1991-01-30

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee