PT94298A - Processo para a preparacao de derivados de 4, 5, 5a, 6-tetra-hidro-3h-isoxazolo{5,4,3-k1}acridinas e de composicoes farmaceuticas que os contem - Google Patents

Processo para a preparacao de derivados de 4, 5, 5a, 6-tetra-hidro-3h-isoxazolo{5,4,3-k1}acridinas e de composicoes farmaceuticas que os contem

Info

Publication number
PT94298A
PT94298A PT94298A PT9429890A PT94298A PT 94298 A PT94298 A PT 94298A PT 94298 A PT94298 A PT 94298A PT 9429890 A PT9429890 A PT 9429890A PT 94298 A PT94298 A PT 94298A
Authority
PT
Portugal
Prior art keywords
chem
loweralkyl
acridines
isoxazole
tetrahydro
Prior art date
Application number
PT94298A
Other languages
English (en)
Other versions
PT94298B (pt
Inventor
Gregory Michael Shutske
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of PT94298A publication Critical patent/PT94298A/pt
Publication of PT94298B publication Critical patent/PT94298B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Liquid Crystal Substances (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PT94298A 1989-06-09 1990-06-07 Processo para a preparacao de derivados de 4, 5, 5a, 6-tetra-hidro-3h-isoxazolo{5,4,3-k1}acridinas e de composicoes farmaceuticas que os contem PT94298B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/364,420 US4920117A (en) 1989-06-09 1989-06-09 4,5,5a,6-tetrahydro-3H-isoxazolo(5,4,3-kl)acridines, pharmaceutical compositions and use

Publications (2)

Publication Number Publication Date
PT94298A true PT94298A (pt) 1991-02-08
PT94298B PT94298B (pt) 1997-01-31

Family

ID=23434459

Family Applications (1)

Application Number Title Priority Date Filing Date
PT94298A PT94298B (pt) 1989-06-09 1990-06-07 Processo para a preparacao de derivados de 4, 5, 5a, 6-tetra-hidro-3h-isoxazolo{5,4,3-k1}acridinas e de composicoes farmaceuticas que os contem

Country Status (17)

Country Link
US (1) US4920117A (pt)
EP (1) EP0401779B1 (pt)
JP (1) JPH089624B2 (pt)
KR (1) KR0148365B1 (pt)
AT (1) ATE122047T1 (pt)
AU (1) AU619985B2 (pt)
CA (1) CA2018564C (pt)
DE (1) DE69019066T2 (pt)
DK (1) DK0401779T3 (pt)
ES (1) ES2072334T3 (pt)
FI (1) FI902851A0 (pt)
IE (1) IE67074B1 (pt)
IL (1) IL94664A (pt)
NO (1) NO902556L (pt)
NZ (1) NZ233971A (pt)
PT (1) PT94298B (pt)
ZA (1) ZA904442B (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4927820A (en) * 1988-11-25 1990-05-22 Hoechst Roussel Pharmaceuticals Inc. Fused heterocyclic derivatives of 1,2,3,4-tetrahydroacridine
US5236930A (en) * 1989-11-13 1993-08-17 Mitbushi Gas Chemical Company, Inc. Oxazopyrroloquinolines and use of oxazopyrroloquinolines
EP1484325B1 (en) * 2002-03-08 2014-06-18 Japan Science and Technology Agency Isoxazole derivatives and process for producing the same

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8314391D0 (en) * 1983-05-24 1983-06-29 Kefalas As Heterocyclic compounds
FR2566407B1 (fr) * 1984-06-25 1986-09-26 Roussel Uclaf Nouveaux derives de l'isoxazoloquinoleine, procede de preparation, application a titre de medicaments, et compositions les renfermant
US4927820A (en) * 1988-11-25 1990-05-22 Hoechst Roussel Pharmaceuticals Inc. Fused heterocyclic derivatives of 1,2,3,4-tetrahydroacridine

Also Published As

Publication number Publication date
DE69019066D1 (de) 1995-06-08
ZA904442B (en) 1991-03-27
AU619985B2 (en) 1992-02-06
JPH089624B2 (ja) 1996-01-31
IE902078L (en) 1990-12-09
US4920117A (en) 1990-04-24
IE67074B1 (en) 1996-02-21
JPH0324085A (ja) 1991-02-01
DE69019066T2 (de) 1995-10-19
EP0401779A1 (en) 1990-12-12
IL94664A (en) 1994-11-11
FI902851A0 (fi) 1990-06-07
DK0401779T3 (da) 1995-10-16
PT94298B (pt) 1997-01-31
ES2072334T3 (es) 1995-07-16
NO902556D0 (no) 1990-06-08
NO902556L (no) 1990-12-10
AU5691790A (en) 1990-12-13
NZ233971A (en) 1992-11-25
IL94664A0 (en) 1991-04-15
EP0401779B1 (en) 1995-05-03
CA2018564A1 (en) 1990-12-09
ATE122047T1 (de) 1995-05-15
CA2018564C (en) 2002-11-12
KR0148365B1 (ko) 1998-11-02
KR910000744A (ko) 1991-01-30

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19961007

MM3A Annulment or lapse

Effective date: 20060407