PT94878A - Processo para a preparacao de 1-(piridinilamino)-2-pirrolidinonas e de composicoes farmaceuticas que os contem - Google Patents
Processo para a preparacao de 1-(piridinilamino)-2-pirrolidinonas e de composicoes farmaceuticas que os contemInfo
- Publication number
- PT94878A PT94878A PT94878A PT9487890A PT94878A PT 94878 A PT94878 A PT 94878A PT 94878 A PT94878 A PT 94878A PT 9487890 A PT9487890 A PT 9487890A PT 94878 A PT94878 A PT 94878A
- Authority
- PT
- Portugal
- Prior art keywords
- pyridinylamino
- pyrrolidinones
- loweralkyl
- preparing
- contain
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/388,413 US4994472A (en) | 1989-08-02 | 1989-08-02 | 1-(pyridinylamino)-2-pyrrolidinones as pain relievers |
Publications (2)
Publication Number | Publication Date |
---|---|
PT94878A true PT94878A (pt) | 1991-04-18 |
PT94878B PT94878B (pt) | 1997-08-29 |
Family
ID=23534027
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT94878A PT94878B (pt) | 1989-08-02 | 1990-08-01 | Processo para a preparacao de 1-(piridinilamino)-2-pirrolidinonas e de composicoes farmaceuticas que os contem |
Country Status (17)
Country | Link |
---|---|
US (1) | US4994472A (pt) |
EP (1) | EP0413191B1 (pt) |
JP (1) | JPH0674264B2 (pt) |
KR (1) | KR0164437B1 (pt) |
AT (1) | ATE109142T1 (pt) |
AU (1) | AU635051B2 (pt) |
CA (1) | CA2022484C (pt) |
DE (1) | DE69011013T2 (pt) |
DK (1) | DK0413191T3 (pt) |
ES (1) | ES2059929T3 (pt) |
FI (1) | FI903818A0 (pt) |
IE (1) | IE65117B1 (pt) |
IL (1) | IL95250A (pt) |
NO (1) | NO903388L (pt) |
NZ (1) | NZ234724A (pt) |
PT (1) | PT94878B (pt) |
ZA (1) | ZA906049B (pt) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5356908A (en) * | 1989-04-21 | 1994-10-18 | E. I. Du Pont De Nemours And Company | Fungicidal oxazolidinones |
DK0435843T3 (da) * | 1989-12-27 | 1994-07-04 | Monsanto Co | Substituerede pyridinforbindelser |
AUPM656594A0 (en) * | 1994-06-30 | 1994-07-21 | Orbital Engine Company (Australia) Proprietary Limited | A method and apparatus relating to control of the operation of an internal combustion engine |
ATE207483T1 (de) * | 1996-04-12 | 2001-11-15 | Aventis Pharma Inc | Isatinderivate als acetylcholinesterase- inhibitoren und analgetika |
US6100276A (en) * | 1996-04-12 | 2000-08-08 | Aventis Pharmaceuticals Inc. | Isatin derivatives as acetylcholinesterase inhibitors and analgesics |
US6825229B2 (en) | 2002-03-07 | 2004-11-30 | Blanchette Rockefeller Neurosciences Institute | Methods for Alzheimer's Disease treatment and cognitive enhancement |
US20050065205A1 (en) | 2002-03-07 | 2005-03-24 | Daniel Alkon | Methods for Alzheimer's disease treatment and cognitive enhance |
KR20050094761A (ko) * | 2002-07-02 | 2005-09-28 | 블랜체트 록펠러 뉴로사이언시즈 인스티튜트 | 브리오스타틴형 화합물을 사용한 sAPPα 분비의 증진및 인지 개선을 위한 수단으로서의 PKC 활성화 |
TW201207390A (en) | 2004-05-18 | 2012-02-16 | Brni Neurosciences Inst | Method for screening agent for antidepressant activity |
GB0412019D0 (en) * | 2004-05-28 | 2004-06-30 | Novartis Ag | Organic compounds |
WO2007016202A1 (en) | 2005-07-29 | 2007-02-08 | Blanchette Rockefeller Neurosciences Institute | Use of a pkc activator, alone or combined with a pkc inhibitor to enhance long term memory |
CN101848726A (zh) | 2007-02-09 | 2010-09-29 | 布朗歇特洛克菲勒神经科学研究所 | 苔藓抑素、苔藓抑素类似物和其它相关物质对头部创伤引起的记忆缺陷和脑损伤的疗效 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1670184A1 (de) * | 1967-01-20 | 1971-01-21 | Boehringer Sohn Ingelheim | Verfahren zur Herstellung heterocyclisch substituierter Hydrazino-imidazoline-(2) |
US4260767A (en) * | 1979-12-26 | 1981-04-07 | American Cyanamid Company | 2-Pyridylhydrazides |
US4324884A (en) * | 1980-09-25 | 1982-04-13 | General Electric Company | Organic amine catalyzed method for making polyetherimide |
US4752610A (en) * | 1985-12-04 | 1988-06-21 | Hoechst-Roussel Pharmaceuticals Inc. | N-(pyrrol-1-yl)pyridinamines having memory enhancing properties |
US4792562A (en) * | 1985-12-04 | 1988-12-20 | Hoechst-Roussel Pharmaceuticals, Inc. | N-(pyrrol-1-yl)pyridinamines having memory enhancing activity |
JPH0699307B2 (ja) * | 1987-08-20 | 1994-12-07 | キッセイ薬品工業株式会社 | 抗痴呆剤 |
US4868190A (en) * | 1988-12-27 | 1989-09-19 | Hoechst-Roussel Pharmaceuticals, Inc. | N-pyridinyl-9H-carbazol-9-amines |
-
1989
- 1989-08-02 US US07/388,413 patent/US4994472A/en not_active Expired - Lifetime
-
1990
- 1990-07-31 IL IL9525090A patent/IL95250A/en active IP Right Revival
- 1990-07-31 DE DE69011013T patent/DE69011013T2/de not_active Expired - Lifetime
- 1990-07-31 ES ES90114659T patent/ES2059929T3/es not_active Expired - Lifetime
- 1990-07-31 AT AT90114659T patent/ATE109142T1/de not_active IP Right Cessation
- 1990-07-31 FI FI903818A patent/FI903818A0/fi not_active Application Discontinuation
- 1990-07-31 NZ NZ234724A patent/NZ234724A/en unknown
- 1990-07-31 EP EP90114659A patent/EP0413191B1/en not_active Expired - Lifetime
- 1990-07-31 DK DK90114659.7T patent/DK0413191T3/da active
- 1990-08-01 AU AU60002/90A patent/AU635051B2/en not_active Ceased
- 1990-08-01 PT PT94878A patent/PT94878B/pt not_active IP Right Cessation
- 1990-08-01 IE IE278690A patent/IE65117B1/en not_active IP Right Cessation
- 1990-08-01 ZA ZA906049A patent/ZA906049B/xx unknown
- 1990-08-01 CA CA002022484A patent/CA2022484C/en not_active Expired - Fee Related
- 1990-08-01 JP JP2202617A patent/JPH0674264B2/ja not_active Expired - Lifetime
- 1990-08-01 KR KR1019900011816A patent/KR0164437B1/ko not_active IP Right Cessation
- 1990-08-01 NO NO90903388A patent/NO903388L/no unknown
Also Published As
Publication number | Publication date |
---|---|
ATE109142T1 (de) | 1994-08-15 |
JPH0368572A (ja) | 1991-03-25 |
NO903388D0 (no) | 1990-08-01 |
KR910004597A (ko) | 1991-03-29 |
NO903388L (no) | 1991-02-04 |
ZA906049B (en) | 1991-04-24 |
IL95250A (en) | 1994-01-25 |
JPH0674264B2 (ja) | 1994-09-21 |
PT94878B (pt) | 1997-08-29 |
DE69011013T2 (de) | 1994-12-22 |
DE69011013D1 (de) | 1994-09-01 |
KR0164437B1 (ko) | 1999-01-15 |
EP0413191B1 (en) | 1994-07-27 |
CA2022484A1 (en) | 1991-02-03 |
CA2022484C (en) | 2000-10-17 |
EP0413191A1 (en) | 1991-02-20 |
US4994472A (en) | 1991-02-19 |
IE65117B1 (en) | 1995-10-04 |
ES2059929T3 (es) | 1994-11-16 |
AU6000290A (en) | 1991-02-07 |
IE902786A1 (en) | 1991-02-27 |
DK0413191T3 (da) | 1994-10-24 |
AU635051B2 (en) | 1993-03-11 |
IL95250A0 (en) | 1991-06-10 |
FI903818A0 (fi) | 1990-07-31 |
NZ234724A (en) | 1992-01-29 |
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PT94878A (pt) | Processo para a preparacao de 1-(piridinilamino)-2-pirrolidinonas e de composicoes farmaceuticas que os contem | |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
BB1A | Laying open of patent application |
Effective date: 19901026 |
|
MM4A | Annulment/lapse due to non-payment of fees, searched and examined patent |
Free format text: MAXIMUM VALIDITY LIMIT REACHED Effective date: 20120523 |