ZA904442B - 4,5,5a,6-tetrahydro-3h-isoxazolo(5,4,3-kl)acridines derivatives,a process for their preparation and their use as medicaments - Google Patents

4,5,5a,6-tetrahydro-3h-isoxazolo(5,4,3-kl)acridines derivatives,a process for their preparation and their use as medicaments

Info

Publication number
ZA904442B
ZA904442B ZA904442A ZA904442A ZA904442B ZA 904442 B ZA904442 B ZA 904442B ZA 904442 A ZA904442 A ZA 904442A ZA 904442 A ZA904442 A ZA 904442A ZA 904442 B ZA904442 B ZA 904442B
Authority
ZA
South Africa
Prior art keywords
chem
loweralkyl
isoxazolo
acridines
medicaments
Prior art date
Application number
ZA904442A
Other languages
English (en)
Inventor
Gregory Michael Shutske
Michael Shutske Gregory
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of ZA904442B publication Critical patent/ZA904442B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Liquid Crystal Substances (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA904442A 1989-06-09 1990-06-08 4,5,5a,6-tetrahydro-3h-isoxazolo(5,4,3-kl)acridines derivatives,a process for their preparation and their use as medicaments ZA904442B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/364,420 US4920117A (en) 1989-06-09 1989-06-09 4,5,5a,6-tetrahydro-3H-isoxazolo(5,4,3-kl)acridines, pharmaceutical compositions and use

Publications (1)

Publication Number Publication Date
ZA904442B true ZA904442B (en) 1991-03-27

Family

ID=23434459

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA904442A ZA904442B (en) 1989-06-09 1990-06-08 4,5,5a,6-tetrahydro-3h-isoxazolo(5,4,3-kl)acridines derivatives,a process for their preparation and their use as medicaments

Country Status (17)

Country Link
US (1) US4920117A (pt)
EP (1) EP0401779B1 (pt)
JP (1) JPH089624B2 (pt)
KR (1) KR0148365B1 (pt)
AT (1) ATE122047T1 (pt)
AU (1) AU619985B2 (pt)
CA (1) CA2018564C (pt)
DE (1) DE69019066T2 (pt)
DK (1) DK0401779T3 (pt)
ES (1) ES2072334T3 (pt)
FI (1) FI902851A0 (pt)
IE (1) IE67074B1 (pt)
IL (1) IL94664A (pt)
NO (1) NO902556L (pt)
NZ (1) NZ233971A (pt)
PT (1) PT94298B (pt)
ZA (1) ZA904442B (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4927820A (en) * 1988-11-25 1990-05-22 Hoechst Roussel Pharmaceuticals Inc. Fused heterocyclic derivatives of 1,2,3,4-tetrahydroacridine
US5236930A (en) * 1989-11-13 1993-08-17 Mitbushi Gas Chemical Company, Inc. Oxazopyrroloquinolines and use of oxazopyrroloquinolines
JP4544864B2 (ja) 2002-03-08 2010-09-15 独立行政法人科学技術振興機構 イソキサゾール誘導体及びその製造方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8314391D0 (en) * 1983-05-24 1983-06-29 Kefalas As Heterocyclic compounds
FR2566407B1 (fr) * 1984-06-25 1986-09-26 Roussel Uclaf Nouveaux derives de l'isoxazoloquinoleine, procede de preparation, application a titre de medicaments, et compositions les renfermant
US4927820A (en) * 1988-11-25 1990-05-22 Hoechst Roussel Pharmaceuticals Inc. Fused heterocyclic derivatives of 1,2,3,4-tetrahydroacridine

Also Published As

Publication number Publication date
PT94298A (pt) 1991-02-08
FI902851A0 (fi) 1990-06-07
NO902556D0 (no) 1990-06-08
EP0401779A1 (en) 1990-12-12
IE67074B1 (en) 1996-02-21
IL94664A0 (en) 1991-04-15
AU619985B2 (en) 1992-02-06
NZ233971A (en) 1992-11-25
JPH089624B2 (ja) 1996-01-31
ATE122047T1 (de) 1995-05-15
KR910000744A (ko) 1991-01-30
CA2018564C (en) 2002-11-12
NO902556L (no) 1990-12-10
CA2018564A1 (en) 1990-12-09
DK0401779T3 (da) 1995-10-16
DE69019066D1 (de) 1995-06-08
IL94664A (en) 1994-11-11
JPH0324085A (ja) 1991-02-01
US4920117A (en) 1990-04-24
IE902078L (en) 1990-12-09
AU5691790A (en) 1990-12-13
ES2072334T3 (es) 1995-07-16
EP0401779B1 (en) 1995-05-03
DE69019066T2 (de) 1995-10-19
KR0148365B1 (ko) 1998-11-02
PT94298B (pt) 1997-01-31

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