DK592589D0 - Kondenserede heterocycliske derivater af 1,2,3,4-tetrahydroacridin, deres fremstilling og anvendelse - Google Patents
Kondenserede heterocycliske derivater af 1,2,3,4-tetrahydroacridin, deres fremstilling og anvendelseInfo
- Publication number
- DK592589D0 DK592589D0 DK592589A DK592589A DK592589D0 DK 592589 D0 DK592589 D0 DK 592589D0 DK 592589 A DK592589 A DK 592589A DK 592589 A DK592589 A DK 592589A DK 592589 D0 DK592589 D0 DK 592589D0
- Authority
- DK
- Denmark
- Prior art keywords
- loweralkyl
- hydrogen
- preparation
- tetrahydroacridine
- condensed heterocyclic
- Prior art date
Links
- RXBYRTSOWREATF-UHFFFAOYSA-N 1,2,3,4-tetrahydroacridine Chemical class C1=CC=C2C=C(CCCC3)C3=NC2=C1 RXBYRTSOWREATF-UHFFFAOYSA-N 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 239000001257 hydrogen Substances 0.000 abstract 4
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 2
- 208000024827 Alzheimer disease Diseases 0.000 abstract 1
- 101100097467 Arabidopsis thaliana SYD gene Chemical group 0.000 abstract 1
- 101100495925 Schizosaccharomyces pombe (strain 972 / ATCC 24843) chr3 gene Chemical group 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 230000006949 cholinergic function Effects 0.000 abstract 1
- 230000003247 decreasing effect Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 230000007074 memory dysfunction Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/06—Peri-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/276,259 US4927820A (en) | 1988-11-25 | 1988-11-25 | Fused heterocyclic derivatives of 1,2,3,4-tetrahydroacridine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK592589D0 true DK592589D0 (da) | 1989-11-24 |
| DK592589A DK592589A (da) | 1990-05-26 |
Family
ID=23055896
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK592589A DK592589A (da) | 1988-11-25 | 1989-11-24 | Kondenserede heterocycliske derivater af 1,2,3,4-tetrahydroacridin, deres fremstilling og anvendelse |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US4927820A (da) |
| EP (1) | EP0370449B1 (da) |
| JP (1) | JPH085881B2 (da) |
| KR (1) | KR0143235B1 (da) |
| AT (1) | ATE104298T1 (da) |
| AU (1) | AU623452B2 (da) |
| CA (1) | CA2003837C (da) |
| DE (1) | DE68914600T2 (da) |
| DK (1) | DK592589A (da) |
| ES (1) | ES2051965T3 (da) |
| FI (1) | FI90871C (da) |
| HU (1) | HU203551B (da) |
| IE (1) | IE63120B1 (da) |
| IL (1) | IL92420A (da) |
| NO (1) | NO173783C (da) |
| NZ (1) | NZ231494A (da) |
| PT (1) | PT92389B (da) |
| ZA (1) | ZA898989B (da) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4920117A (en) * | 1989-06-09 | 1990-04-24 | Hoechst-Roussel Pharmaceuticals Inc. | 4,5,5a,6-tetrahydro-3H-isoxazolo(5,4,3-kl)acridines, pharmaceutical compositions and use |
| US4994452A (en) * | 1989-11-28 | 1991-02-19 | Hoechst-Roussel Pharmaceuticals Inc. | Hexahydro-1H-quino[4,3,2-ef][1,4]benzoxazepines and related compounds |
| US5112829A (en) * | 1989-11-28 | 1992-05-12 | Hoechst-Roussel Pharmaceuticals Inc. | Hexahydro-1H-quino[4,3,2-ef][1,4]benzoxazepines and related compounds |
| US5861398A (en) * | 1996-08-26 | 1999-01-19 | Alanex Corporation | Benzoperimidine-carboxylic acids and derivatives thereof |
| JP5406215B2 (ja) * | 2008-01-25 | 2014-02-05 | ハイ ポイント ファーマシューティカルズ，リミティド ライアビリティ カンパニー | ＴＮＦ−α合成の調節因子及びＰＤＥ４阻害剤としての三環系化合物 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4695573A (en) * | 1984-10-25 | 1987-09-22 | Hoechst-Roussel Pharmaceuticals Inc. | 9-amino-1,2,3,4-tetrahydroacridin-1-ol and related compounds |
| DE3582995D1 (de) * | 1984-10-25 | 1991-07-04 | Hoechst Roussel Pharma | 9-amino-1,2,3,4-tetrahydroacridin-1-ol und verwandte verbindungen, verfahren zu ihrer herstellung und verwendung als arzneimittel. |
| WO1989002739A1 (en) * | 1987-10-05 | 1989-04-06 | Pfizer Inc. | 4-aminopyridine derivatives |
| US4920117A (en) * | 1989-06-09 | 1990-04-24 | Hoechst-Roussel Pharmaceuticals Inc. | 4,5,5a,6-tetrahydro-3H-isoxazolo(5,4,3-kl)acridines, pharmaceutical compositions and use |
-
1988
- 1988-11-25 US US07/276,259 patent/US4927820A/en not_active Expired - Fee Related
-
1989
- 1989-11-21 EP EP89121488A patent/EP0370449B1/en not_active Expired - Lifetime
- 1989-11-21 DE DE68914600T patent/DE68914600T2/de not_active Expired - Fee Related
- 1989-11-21 ES ES89121488T patent/ES2051965T3/es not_active Expired - Lifetime
- 1989-11-21 AT AT89121488T patent/ATE104298T1/de not_active IP Right Cessation
- 1989-11-23 PT PT92389A patent/PT92389B/pt not_active IP Right Cessation
- 1989-11-23 NZ NZ231494A patent/NZ231494A/en unknown
- 1989-11-23 FI FI895605A patent/FI90871C/fi not_active IP Right Cessation
- 1989-11-23 IL IL9242089A patent/IL92420A/en not_active IP Right Cessation
- 1989-11-23 KR KR1019890017024A patent/KR0143235B1/ko not_active IP Right Cessation
- 1989-11-24 NO NO894698A patent/NO173783C/no not_active IP Right Cessation
- 1989-11-24 IE IE375889A patent/IE63120B1/en not_active IP Right Cessation
- 1989-11-24 JP JP1303465A patent/JPH085881B2/ja not_active Expired - Fee Related
- 1989-11-24 DK DK592589A patent/DK592589A/da not_active Application Discontinuation
- 1989-11-24 ZA ZA898989A patent/ZA898989B/xx unknown
- 1989-11-24 HU HU896174A patent/HU203551B/hu not_active IP Right Cessation
- 1989-11-24 CA CA002003837A patent/CA2003837C/en not_active Expired - Fee Related
- 1989-11-24 AU AU45480/89A patent/AU623452B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| IE63120B1 (en) | 1995-03-22 |
| AU4548089A (en) | 1990-05-31 |
| EP0370449B1 (en) | 1994-04-13 |
| KR900007848A (ko) | 1990-06-02 |
| KR0143235B1 (ko) | 1998-07-15 |
| EP0370449A1 (en) | 1990-05-30 |
| JPH085881B2 (ja) | 1996-01-24 |
| ZA898989B (en) | 1990-08-29 |
| ES2051965T3 (es) | 1994-07-01 |
| IE893758L (en) | 1990-05-25 |
| FI895605A0 (fi) | 1989-11-23 |
| NO173783C (no) | 1994-02-02 |
| IL92420A (en) | 1994-02-27 |
| AU623452B2 (en) | 1992-05-14 |
| HU203551B (en) | 1991-08-28 |
| IL92420A0 (en) | 1990-07-26 |
| NO173783B (no) | 1993-10-25 |
| CA2003837C (en) | 2000-01-18 |
| FI90871B (fi) | 1993-12-31 |
| ATE104298T1 (de) | 1994-04-15 |
| US4927820A (en) | 1990-05-22 |
| HU896174D0 (en) | 1990-02-28 |
| HUT53107A (en) | 1990-09-28 |
| PT92389B (pt) | 1995-07-18 |
| JPH02193996A (ja) | 1990-07-31 |
| DE68914600T2 (de) | 1994-09-15 |
| NZ231494A (en) | 1992-04-28 |
| DK592589A (da) | 1990-05-26 |
| PT92389A (pt) | 1990-05-31 |
| CA2003837A1 (en) | 1990-05-25 |
| NO894698D0 (no) | 1989-11-24 |
| DE68914600D1 (de) | 1994-05-19 |
| NO894698L (no) | 1990-05-28 |
| FI90871C (fi) | 1994-04-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHS | Application shelved for other reasons than non-payment |